ES3064674T3 - Heteroaryl-biphenyl amines for the treatment of pd-l1 diseases - Google Patents

Heteroaryl-biphenyl amines for the treatment of pd-l1 diseases

Info

Publication number
ES3064674T3
ES3064674T3 ES20877362T ES20877362T ES3064674T3 ES 3064674 T3 ES3064674 T3 ES 3064674T3 ES 20877362 T ES20877362 T ES 20877362T ES 20877362 T ES20877362 T ES 20877362T ES 3064674 T3 ES3064674 T3 ES 3064674T3
Authority
ES
Spain
Prior art keywords
group
methyl
compound
amino
biphenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES20877362T
Other languages
English (en)
Spanish (es)
Inventor
Pingchen Fan
Christopher W Lange
Rebecca M Lui
Darren J Mcmurtrie
Ryan J Scamp
Ju Yang
Yibin Zeng
Penglie Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemocentryx Inc
Original Assignee
Chemocentryx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemocentryx Inc filed Critical Chemocentryx Inc
Application granted granted Critical
Publication of ES3064674T3 publication Critical patent/ES3064674T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES20877362T 2019-10-16 2020-10-15 Heteroaryl-biphenyl amines for the treatment of pd-l1 diseases Active ES3064674T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962915771P 2019-10-16 2019-10-16
PCT/US2020/055669 WO2021076688A1 (en) 2019-10-16 2020-10-15 Heteroaryl-biphenyl amines for the treatment of pd-l1 diseases

Publications (1)

Publication Number Publication Date
ES3064674T3 true ES3064674T3 (en) 2026-04-28

Family

ID=75538872

Family Applications (1)

Application Number Title Priority Date Filing Date
ES20877362T Active ES3064674T3 (en) 2019-10-16 2020-10-15 Heteroaryl-biphenyl amines for the treatment of pd-l1 diseases

Country Status (20)

Country Link
US (3) US11866429B2 (enExample)
EP (1) EP4045037B1 (enExample)
JP (1) JP7686634B2 (enExample)
KR (1) KR20220083775A (enExample)
CN (1) CN114555080B (enExample)
AR (1) AR120246A1 (enExample)
AU (1) AU2020368392B2 (enExample)
BR (1) BR112022006279A2 (enExample)
CA (1) CA3152714A1 (enExample)
CL (2) CL2022000955A1 (enExample)
CO (1) CO2022004698A2 (enExample)
CR (1) CR20220216A (enExample)
EC (1) ECSP22038509A (enExample)
ES (1) ES3064674T3 (enExample)
IL (1) IL291735A (enExample)
MX (1) MX2022004450A (enExample)
PE (1) PE20221764A1 (enExample)
PH (1) PH12022550877A1 (enExample)
TW (1) TWI873207B (enExample)
WO (1) WO2021076688A1 (enExample)

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