ES2980790T3 - Acidos grasos estructuralmente mejorados que contienen azufre para su uso en el tratamiento de la esteatohepatitis no alcohólica - Google Patents

Acidos grasos estructuralmente mejorados que contienen azufre para su uso en el tratamiento de la esteatohepatitis no alcohólica Download PDF

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Publication number
ES2980790T3
ES2980790T3 ES16717933T ES16717933T ES2980790T3 ES 2980790 T3 ES2980790 T3 ES 2980790T3 ES 16717933 T ES16717933 T ES 16717933T ES 16717933 T ES16717933 T ES 16717933T ES 2980790 T3 ES2980790 T3 ES 2980790T3
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Prior art keywords
compound
use according
ester
compound according
ethyl
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English (en)
Spanish (es)
Inventor
Hilde Steineger
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BASF AS
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BASF AS
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fats And Perfumes (AREA)
ES16717933T 2015-04-28 2016-04-21 Acidos grasos estructuralmente mejorados que contienen azufre para su uso en el tratamiento de la esteatohepatitis no alcohólica Active ES2980790T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NO20150514 2015-04-28
PCT/EP2016/058909 WO2016173923A1 (en) 2015-04-28 2016-04-21 Use of structurally enhanced fatty acids containing sulphur for preventing and/or treating non-alcoholic steatohepatitis

Publications (1)

Publication Number Publication Date
ES2980790T3 true ES2980790T3 (es) 2024-10-03

Family

ID=55806346

Family Applications (1)

Application Number Title Priority Date Filing Date
ES16717933T Active ES2980790T3 (es) 2015-04-28 2016-04-21 Acidos grasos estructuralmente mejorados que contienen azufre para su uso en el tratamiento de la esteatohepatitis no alcohólica

Country Status (10)

Country Link
US (5) US20180104201A1 (enExample)
EP (1) EP3288550B1 (enExample)
JP (3) JP6784696B2 (enExample)
KR (2) KR20240033300A (enExample)
CN (2) CN115025079A (enExample)
AU (2) AU2016256552B2 (enExample)
BR (1) BR112017023164A2 (enExample)
CA (1) CA2983377C (enExample)
ES (1) ES2980790T3 (enExample)
WO (1) WO2016173923A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20240033300A (ko) 2015-04-28 2024-03-12 바스프 에이에스 비알코올성 지방간염의 예방 및/또는 치료를 위한 구조적으로 강화된 함황 지방산의 용도
US20220257531A1 (en) * 2017-06-16 2022-08-18 Avexxin As Compositions and methods for treatment of a fibrotic disease
EP3720431B1 (en) 2017-12-06 2024-10-30 Basf As Fatty acid derivatives for treating non-alcoholic steatohepatitis
KR20210015883A (ko) * 2018-05-23 2021-02-10 노스씨 테라퓨틱스 비.브이. 당뇨 제어 및 염증성장질환 치료의 향상을 위한 구조적으로 변형된 지방산
KR102186416B1 (ko) 2019-01-16 2020-12-07 서울대학교산학협력단 12-lox 발현 촉진제를 포함하는 간 질환 예방 또는 치료용 조성물
AU2021405273A1 (en) 2020-12-22 2023-08-10 Northsea Therapeutics B.V. Combination therapies comprising oxygen-containing structurally enhanced fatty acids for treatment of non-alcoholic steatohepatitis

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Also Published As

Publication number Publication date
AU2016256552B2 (en) 2021-04-01
WO2016173923A1 (en) 2016-11-03
CN115025079A (zh) 2022-09-09
US20200085772A1 (en) 2020-03-19
CN107530306A (zh) 2018-01-02
BR112017023164A2 (en) 2018-07-24
JP2023116579A (ja) 2023-08-22
JP6784696B2 (ja) 2020-11-11
US20190314304A1 (en) 2019-10-17
JP2018515463A (ja) 2018-06-14
CA2983377C (en) 2023-08-29
JP7524411B2 (ja) 2024-07-29
KR20170140376A (ko) 2017-12-20
CA2983377A1 (en) 2016-11-03
AU2016256552A1 (en) 2017-11-16
AU2021204406B2 (en) 2023-08-10
US20240156760A1 (en) 2024-05-16
EP3288550A1 (en) 2018-03-07
US20180104201A1 (en) 2018-04-19
AU2021204406A1 (en) 2021-07-22
KR102644400B1 (ko) 2024-03-06
US10722481B2 (en) 2020-07-28
JP2021035956A (ja) 2021-03-04
US12465580B2 (en) 2025-11-11
US11911354B2 (en) 2024-02-27
EP3288550B1 (en) 2024-06-05
EP3288550C0 (en) 2024-06-05
US20220280459A1 (en) 2022-09-08
KR20240033300A (ko) 2024-03-12
US11234948B2 (en) 2022-02-01

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