CA2983377C - Use of structurally enhanced fatty acids containing sulphur for preventing and/or treating non-alcoholic steatohepatitis - Google Patents

Use of structurally enhanced fatty acids containing sulphur for preventing and/or treating non-alcoholic steatohepatitis Download PDF

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Publication number
CA2983377C
CA2983377C CA2983377A CA2983377A CA2983377C CA 2983377 C CA2983377 C CA 2983377C CA 2983377 A CA2983377 A CA 2983377A CA 2983377 A CA2983377 A CA 2983377A CA 2983377 C CA2983377 C CA 2983377C
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icosa
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French (fr)
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CA2983377A1 (en
Inventor
Hilde STEINEGER
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Pronova Biopharma Norge AS
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Pronova Biopharma Norge AS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fats And Perfumes (AREA)
CA2983377A 2015-04-28 2016-04-21 Use of structurally enhanced fatty acids containing sulphur for preventing and/or treating non-alcoholic steatohepatitis Active CA2983377C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO20150514 2015-04-28
NO20150514 2015-04-28
PCT/EP2016/058909 WO2016173923A1 (en) 2015-04-28 2016-04-21 Use of structurally enhanced fatty acids containing sulphur for preventing and/or treating non-alcoholic steatohepatitis

Publications (2)

Publication Number Publication Date
CA2983377A1 CA2983377A1 (en) 2016-11-03
CA2983377C true CA2983377C (en) 2023-08-29

Family

ID=55806346

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2983377A Active CA2983377C (en) 2015-04-28 2016-04-21 Use of structurally enhanced fatty acids containing sulphur for preventing and/or treating non-alcoholic steatohepatitis

Country Status (10)

Country Link
US (5) US20180104201A1 (enExample)
EP (1) EP3288550B1 (enExample)
JP (3) JP6784696B2 (enExample)
KR (2) KR102644400B1 (enExample)
CN (2) CN107530306A (enExample)
AU (2) AU2016256552B2 (enExample)
BR (1) BR112017023164A2 (enExample)
CA (1) CA2983377C (enExample)
ES (1) ES2980790T3 (enExample)
WO (1) WO2016173923A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016256552B2 (en) * 2015-04-28 2021-04-01 Pronova Biopharma Norge As Use of structurally enhanced fatty acids containing sulphur for preventing and/or treating non-alcoholic steatohepatitis
JP7305562B2 (ja) * 2017-06-16 2023-07-10 アヴェクシン エーエス 線維性疾患の治療のための組成物および方法
IL308604B2 (en) * 2017-12-06 2025-08-01 Basf As Fatty acid derivatives for treating non-alcoholic steatohepatitis
KR20210015883A (ko) * 2018-05-23 2021-02-10 노스씨 테라퓨틱스 비.브이. 당뇨 제어 및 염증성장질환 치료의 향상을 위한 구조적으로 변형된 지방산
KR102186416B1 (ko) 2019-01-16 2020-12-07 서울대학교산학협력단 12-lox 발현 촉진제를 포함하는 간 질환 예방 또는 치료용 조성물
JP2023554524A (ja) * 2020-12-22 2023-12-27 ノースシー セラピューティクス ベスローテン フェンノートシャップ 非アルコール性脂肪性肝炎の治療のための酸素含有構造強化脂肪酸を含む組合せ療法
KR20250136619A (ko) 2024-03-08 2025-09-16 주식회사 엘지에너지솔루션 배터리 관리 장치 및 방법

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Also Published As

Publication number Publication date
AU2016256552A1 (en) 2017-11-16
US11234948B2 (en) 2022-02-01
US12465580B2 (en) 2025-11-11
JP6784696B2 (ja) 2020-11-11
US20240156760A1 (en) 2024-05-16
EP3288550A1 (en) 2018-03-07
WO2016173923A1 (en) 2016-11-03
US10722481B2 (en) 2020-07-28
US20190314304A1 (en) 2019-10-17
ES2980790T3 (es) 2024-10-03
KR20170140376A (ko) 2017-12-20
CN115025079A (zh) 2022-09-09
JP2018515463A (ja) 2018-06-14
CA2983377A1 (en) 2016-11-03
KR102644400B1 (ko) 2024-03-06
BR112017023164A2 (en) 2018-07-24
JP2021035956A (ja) 2021-03-04
US20220280459A1 (en) 2022-09-08
AU2016256552B2 (en) 2021-04-01
AU2021204406A1 (en) 2021-07-22
US20180104201A1 (en) 2018-04-19
US20200085772A1 (en) 2020-03-19
EP3288550C0 (en) 2024-06-05
KR20240033300A (ko) 2024-03-12
US11911354B2 (en) 2024-02-27
JP2023116579A (ja) 2023-08-22
AU2021204406B2 (en) 2023-08-10
CN107530306A (zh) 2018-01-02
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