ES2968840T3 - Compuestos de aminocarbonilcarbamato y su uso en el tratamiento de trastornos hipercinéticos tales como el TDAH - Google Patents

Compuestos de aminocarbonilcarbamato y su uso en el tratamiento de trastornos hipercinéticos tales como el TDAH Download PDF

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Publication number
ES2968840T3
ES2968840T3 ES19188405T ES19188405T ES2968840T3 ES 2968840 T3 ES2968840 T3 ES 2968840T3 ES 19188405 T ES19188405 T ES 19188405T ES 19188405 T ES19188405 T ES 19188405T ES 2968840 T3 ES2968840 T3 ES 2968840T3
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ES
Spain
Prior art keywords
acid
compound
pharmaceutical composition
amino
phenylpropyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES19188405T
Other languages
English (en)
Spanish (es)
Inventor
Young Soon Kang
Jin Yong Chung
Cheol Young Maeng
Han Ju Yi
Ki Ho Lee
Joon Heo
Eun Hee Chae
Yu Jin Shin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SK Biopharmaceuticals Co Ltd
Original Assignee
SK Biopharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by SK Biopharmaceuticals Co Ltd filed Critical SK Biopharmaceuticals Co Ltd
Application granted granted Critical
Publication of ES2968840T3 publication Critical patent/ES2968840T3/es
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/58Y being a hetero atom
    • C07C275/60Y being an oxygen atom, e.g. allophanic acids

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES19188405T 2014-02-28 2015-02-27 Compuestos de aminocarbonilcarbamato y su uso en el tratamiento de trastornos hipercinéticos tales como el TDAH Active ES2968840T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461946142P 2014-02-28 2014-02-28

Publications (1)

Publication Number Publication Date
ES2968840T3 true ES2968840T3 (es) 2024-05-14

Family

ID=54006446

Family Applications (2)

Application Number Title Priority Date Filing Date
ES19188405T Active ES2968840T3 (es) 2014-02-28 2015-02-27 Compuestos de aminocarbonilcarbamato y su uso en el tratamiento de trastornos hipercinéticos tales como el TDAH
ES15754658T Active ES2759312T3 (es) 2014-02-28 2015-02-27 Compuestos de aminocarbonilcarbamato

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES15754658T Active ES2759312T3 (es) 2014-02-28 2015-02-27 Compuestos de aminocarbonilcarbamato

Country Status (15)

Country Link
US (4) US9403761B2 (enExample)
EP (2) EP3110792B1 (enExample)
JP (2) JP6452731B2 (enExample)
KR (2) KR102487051B1 (enExample)
CN (2) CN106458866B (enExample)
AR (1) AR099581A1 (enExample)
AU (2) AU2015223579B2 (enExample)
CA (1) CA2939835C (enExample)
CL (1) CL2016002165A1 (enExample)
ES (2) ES2968840T3 (enExample)
MX (2) MX387796B (enExample)
PL (1) PL3110792T3 (enExample)
RU (1) RU2688673C2 (enExample)
TW (2) TWI698415B (enExample)
WO (1) WO2015130121A1 (enExample)

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* Cited by examiner, † Cited by third party
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TWI698415B (zh) * 2014-02-28 2020-07-11 南韓商愛思開生物製藥股份有限公司 胺基羰基胺基甲酸酯化合物
US10888542B2 (en) * 2014-02-28 2021-01-12 Sk Biopharmaceuticals Co., Ltd. Aminocarbonylcarbamate compounds
CA3036071A1 (en) 2016-09-06 2018-03-15 Jazz Pharmaceuticals International Iii Limited Solvate form of (r)-2-amino-3-phenylpropyl carbamate
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
CN110049966A (zh) 2016-10-06 2019-07-23 杰资制药国际三期有限公司 氨基甲酰基苯丙氨醇化合物及其用途
JP2020528075A (ja) 2017-06-02 2020-09-17 ジャズ ファーマシューティカルズ アイルランド リミテッド 過度の眠気を処置するための方法および組成物
CN111153863A (zh) * 2019-12-13 2020-05-15 浙江工业大学 一种合成动物用抗球虫药物妥曲珠利的方法
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function
KR102390194B1 (ko) 2020-08-03 2022-04-25 셀라이온바이오메드 주식회사 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물

Family Cites Families (23)

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US5077289A (en) * 1989-11-30 1991-12-31 Hoechst Roussel Pharmaceuticals Inc. Memory enhancing and analgesic aminocarbonylcarbamates related to physostigmine
WO1994010158A1 (fr) * 1992-10-28 1994-05-11 Toyama Chemical Co., Ltd. Nouveaux derives de 1,2-benzisoxazole ou sel dudit derive, et agent de protection cerebrale contenant ce derive
KR100197892B1 (ko) * 1994-09-09 1999-06-15 남창우 신규한 페닐알킬아미노 카바메이트 화합물과 그의 제조방법
KR0173862B1 (ko) * 1995-02-11 1999-04-01 조규향 O-카바모일-(d)-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법
US5756817C1 (en) 1995-02-11 2001-04-17 Sk Corp O-carbamoyl-phenylananinol compounds their pharmaceutically useful salts and process for preparing the same
KR0173863B1 (ko) 1995-04-10 1999-04-01 조규향 페닐에 치환체가 있는 o-카바모일-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법
WO2004111006A1 (en) * 2003-06-12 2004-12-23 Novo Nordisk A/S Para-subtituted phenyl carbamates as inhibitors of hormone sensitive lipase
US20050080268A1 (en) 2003-10-08 2005-04-14 Yong-Moon Choi Process of preparing O-carbamoyl compounds in the presence of active amine group
AU2004285893B2 (en) * 2003-10-21 2011-12-15 Colucid Pharmaceuticals, Inc. Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents
CA2587481A1 (en) 2004-10-28 2006-05-11 Sk Corporation Phenylalkylamino carbamates adjunctive therapy for depression
US7598279B2 (en) * 2005-04-22 2009-10-06 Sk Holdings Co., Ltd. Neurotherapeutic azole compounds
WO2006133393A1 (en) 2005-06-08 2006-12-14 Sk Holdings Co., Ltd. Treatment of sleep-wake disorders
CA2612672C (en) 2005-06-22 2014-10-14 Janssen Pharmaceutica, N.V. Treatment for sexual dysfunction
TW200820963A (en) * 2006-07-28 2008-05-16 Xenoport Inc Acyloxyalkyl carbamate prodrugs of α-amino acids, methods of synthesis and use
CN101631770A (zh) * 2007-02-02 2010-01-20 科露西德医药品公司 抑制胆碱酯酶的化合物
KR20120098578A (ko) 2009-06-22 2012-09-05 에스케이바이오팜 주식회사 피로의 치료 또는 예방 방법
US8232315B2 (en) * 2009-06-26 2012-07-31 Sk Biopharmaceuticals Co., Ltd. Methods for treating drug addiction and improving addiction-related behavior
US8895609B2 (en) * 2009-11-06 2014-11-25 Sk Biopharmaceuticals Co., Ltd. Methods for treating attention-deficit/hyperactivity disorder
ES2743153T3 (es) 2009-11-06 2020-02-18 Sk Biopharmaceuticals Co Ltd Métodos para tratar el síndrome de fibromialgia
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
US8623913B2 (en) * 2010-06-30 2014-01-07 Sk Biopharmaceuticals Co., Ltd. Methods for treating restless legs syndrome
CN110638804A (zh) * 2013-07-18 2020-01-03 爵士制药国际Iii有限公司 治疗肥胖
TWI698415B (zh) * 2014-02-28 2020-07-11 南韓商愛思開生物製藥股份有限公司 胺基羰基胺基甲酸酯化合物

Also Published As

Publication number Publication date
US20150246874A1 (en) 2015-09-03
EP3110792A1 (en) 2017-01-04
KR20160126988A (ko) 2016-11-02
TWI655179B (zh) 2019-04-01
RU2688673C2 (ru) 2019-05-22
KR20210124520A (ko) 2021-10-14
PL3110792T3 (pl) 2020-02-28
EP3587394A1 (en) 2020-01-01
US10314808B2 (en) 2019-06-11
ES2759312T3 (es) 2020-05-08
US10485781B2 (en) 2019-11-26
JP2019059764A (ja) 2019-04-18
AU2019236666B2 (en) 2021-03-25
CN106458866B (zh) 2018-12-07
KR102487051B1 (ko) 2023-01-09
AU2015223579B2 (en) 2019-06-27
AU2019236666A1 (en) 2019-10-17
CN106458866A (zh) 2017-02-22
CA2939835C (en) 2022-11-01
EP3110792A4 (en) 2017-09-27
RU2016136193A (ru) 2018-03-30
RU2016136193A3 (enExample) 2018-10-29
US20190247356A1 (en) 2019-08-15
AU2015223579A1 (en) 2016-08-25
US9403761B2 (en) 2016-08-02
MX2020003020A (es) 2021-11-11
CN109627186B (zh) 2021-10-29
KR102309903B1 (ko) 2021-10-06
AR099581A1 (es) 2016-08-03
CL2016002165A1 (es) 2017-06-09
US9833432B2 (en) 2017-12-05
CA2939835A1 (en) 2015-09-03
TWI698415B (zh) 2020-07-11
TW201920086A (zh) 2019-06-01
RU2019113158A (ru) 2019-06-25
JP6452731B2 (ja) 2019-01-16
US20160303067A1 (en) 2016-10-20
JP6595078B2 (ja) 2019-10-23
WO2015130121A1 (en) 2015-09-03
JP2017512211A (ja) 2017-05-18
MX2016010973A (es) 2016-11-29
TW201623224A (zh) 2016-07-01
MX387796B (es) 2025-03-19
CN109627186A (zh) 2019-04-16
US20180085337A1 (en) 2018-03-29
EP3587394B1 (en) 2023-11-01
EP3110792B1 (en) 2019-09-04

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