KR102309903B1 - 아미노카보닐카바메이트 화합물 - Google Patents

아미노카보닐카바메이트 화합물 Download PDF

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Publication number
KR102309903B1
KR102309903B1 KR1020167022646A KR20167022646A KR102309903B1 KR 102309903 B1 KR102309903 B1 KR 102309903B1 KR 1020167022646 A KR1020167022646 A KR 1020167022646A KR 20167022646 A KR20167022646 A KR 20167022646A KR 102309903 B1 KR102309903 B1 KR 102309903B1
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South Korea
Prior art keywords
aminocarbonyl
amino
propyl
methylcarbamate
carbamate
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KR1020167022646A
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English (en)
Korean (ko)
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KR20160126988A (ko
Inventor
강영순
정진용
맹철영
이한주
이기호
허준
채은희
신유진
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에스케이바이오팜 주식회사
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Priority to KR1020217031464A priority Critical patent/KR102487051B1/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/58—Y being a hetero atom
    • C07C275/60—Y being an oxygen atom, e.g. allophanic acids

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020167022646A 2014-02-28 2015-02-27 아미노카보닐카바메이트 화합물 Active KR102309903B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020217031464A KR102487051B1 (ko) 2014-02-28 2015-02-27 아미노카보닐카바메이트 화합물

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461946142P 2014-02-28 2014-02-28
US61/946,142 2014-02-28
PCT/KR2015/001915 WO2015130121A1 (en) 2014-02-28 2015-02-27 Aminocarbonylcarbamate compounds

Related Child Applications (1)

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KR1020217031464A Division KR102487051B1 (ko) 2014-02-28 2015-02-27 아미노카보닐카바메이트 화합물

Publications (2)

Publication Number Publication Date
KR20160126988A KR20160126988A (ko) 2016-11-02
KR102309903B1 true KR102309903B1 (ko) 2021-10-06

Family

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KR1020167022646A Active KR102309903B1 (ko) 2014-02-28 2015-02-27 아미노카보닐카바메이트 화합물
KR1020217031464A Active KR102487051B1 (ko) 2014-02-28 2015-02-27 아미노카보닐카바메이트 화합물

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Country Status (15)

Country Link
US (4) US9403761B2 (enExample)
EP (2) EP3587394B1 (enExample)
JP (2) JP6452731B2 (enExample)
KR (2) KR102309903B1 (enExample)
CN (2) CN109627186B (enExample)
AR (1) AR099581A1 (enExample)
AU (2) AU2015223579B2 (enExample)
CA (1) CA2939835C (enExample)
CL (1) CL2016002165A1 (enExample)
ES (2) ES2968840T3 (enExample)
MX (2) MX387796B (enExample)
PL (1) PL3110792T3 (enExample)
RU (1) RU2688673C2 (enExample)
TW (2) TWI655179B (enExample)
WO (1) WO2015130121A1 (enExample)

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US10888542B2 (en) 2014-02-28 2021-01-12 Sk Biopharmaceuticals Co., Ltd. Aminocarbonylcarbamate compounds
TWI655179B (zh) * 2014-02-28 2019-04-01 南韓商愛思開生物製藥股份有限公司 胺基羰基胺基甲酸酯化合物
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
MY197630A (en) * 2016-09-06 2023-06-29 Sk Biopharmaceuticals Co Ltd Solvate form of (r)-2-amino-3-phenylpropyl carbamate
EP4316592A3 (en) 2016-10-06 2024-05-01 Axsome Malta Ltd. Carbamoyl phenylalaninol compounds and uses thereof
JP2020528075A (ja) 2017-06-02 2020-09-17 ジャズ ファーマシューティカルズ アイルランド リミテッド 過度の眠気を処置するための方法および組成物
CN111153863A (zh) * 2019-12-13 2020-05-15 浙江工业大学 一种合成动物用抗球虫药物妥曲珠利的方法
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function
KR102390194B1 (ko) 2020-08-03 2022-04-25 셀라이온바이오메드 주식회사 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물

Citations (1)

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AU674358B2 (en) * 1992-10-28 1996-12-19 Toyama Chemical Co. Ltd. Novel 1,2-benzoisoxazole derivative or its salt and brain -protecting agent comprising the same
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KR0173862B1 (ko) * 1995-02-11 1999-04-01 조규향 O-카바모일-(d)-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법
US5756817C1 (en) 1995-02-11 2001-04-17 Sk Corp O-carbamoyl-phenylananinol compounds their pharmaceutically useful salts and process for preparing the same
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TWI655179B (zh) * 2014-02-28 2019-04-01 南韓商愛思開生物製藥股份有限公司 胺基羰基胺基甲酸酯化合物

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Also Published As

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US20180085337A1 (en) 2018-03-29
AU2015223579A1 (en) 2016-08-25
TW201623224A (zh) 2016-07-01
AU2019236666B2 (en) 2021-03-25
US10314808B2 (en) 2019-06-11
AU2015223579B2 (en) 2019-06-27
EP3587394A1 (en) 2020-01-01
PL3110792T3 (pl) 2020-02-28
RU2016136193A3 (enExample) 2018-10-29
US20160303067A1 (en) 2016-10-20
EP3110792A1 (en) 2017-01-04
EP3110792A4 (en) 2017-09-27
JP2019059764A (ja) 2019-04-18
RU2019113158A (ru) 2019-06-25
CA2939835A1 (en) 2015-09-03
CN106458866B (zh) 2018-12-07
CL2016002165A1 (es) 2017-06-09
RU2688673C2 (ru) 2019-05-22
MX387796B (es) 2025-03-19
WO2015130121A1 (en) 2015-09-03
AU2019236666A1 (en) 2019-10-17
JP6595078B2 (ja) 2019-10-23
TWI698415B (zh) 2020-07-11
TW201920086A (zh) 2019-06-01
US10485781B2 (en) 2019-11-26
US9833432B2 (en) 2017-12-05
MX2016010973A (es) 2016-11-29
KR20160126988A (ko) 2016-11-02
ES2968840T3 (es) 2024-05-14
TWI655179B (zh) 2019-04-01
MX2020003020A (es) 2021-11-11
JP6452731B2 (ja) 2019-01-16
EP3587394B1 (en) 2023-11-01
US9403761B2 (en) 2016-08-02
CN106458866A (zh) 2017-02-22
CN109627186A (zh) 2019-04-16
KR102487051B1 (ko) 2023-01-09
AR099581A1 (es) 2016-08-03
EP3110792B1 (en) 2019-09-04
CN109627186B (zh) 2021-10-29
ES2759312T3 (es) 2020-05-08
JP2017512211A (ja) 2017-05-18
KR20210124520A (ko) 2021-10-14
US20190247356A1 (en) 2019-08-15
RU2016136193A (ru) 2018-03-30
CA2939835C (en) 2022-11-01
US20150246874A1 (en) 2015-09-03

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