AU2015223579B2 - Aminocarbonylcarbamate compounds - Google Patents

Aminocarbonylcarbamate compounds Download PDF

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Publication number
AU2015223579B2
AU2015223579B2 AU2015223579A AU2015223579A AU2015223579B2 AU 2015223579 B2 AU2015223579 B2 AU 2015223579B2 AU 2015223579 A AU2015223579 A AU 2015223579A AU 2015223579 A AU2015223579 A AU 2015223579A AU 2015223579 B2 AU2015223579 B2 AU 2015223579B2
Authority
AU
Australia
Prior art keywords
aminocarbonyl
amino
propyl
methylcarbamate
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2015223579A
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English (en)
Other versions
AU2015223579A1 (en
Inventor
Eun Hee Chae
Jin Yong Chung
Joon Heo
Young Soon Kang
Ki Ho Lee
Cheol Young Maeng
Yu Jin Shin
Han Ju Yi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SK Biopharmaceuticals Co Ltd
Original Assignee
SK Biopharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SK Biopharmaceuticals Co Ltd filed Critical SK Biopharmaceuticals Co Ltd
Publication of AU2015223579A1 publication Critical patent/AU2015223579A1/en
Application granted granted Critical
Publication of AU2015223579B2 publication Critical patent/AU2015223579B2/en
Priority to AU2019236666A priority Critical patent/AU2019236666B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/58—Y being a hetero atom
    • C07C275/60—Y being an oxygen atom, e.g. allophanic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2015223579A 2014-02-28 2015-02-27 Aminocarbonylcarbamate compounds Active AU2015223579B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2019236666A AU2019236666B2 (en) 2014-02-28 2019-09-25 Aminocarbonylcarbamate compounds

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461946142P 2014-02-28 2014-02-28
US61/946,142 2014-02-28
PCT/KR2015/001915 WO2015130121A1 (en) 2014-02-28 2015-02-27 Aminocarbonylcarbamate compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2019236666A Division AU2019236666B2 (en) 2014-02-28 2019-09-25 Aminocarbonylcarbamate compounds

Publications (2)

Publication Number Publication Date
AU2015223579A1 AU2015223579A1 (en) 2016-08-25
AU2015223579B2 true AU2015223579B2 (en) 2019-06-27

Family

ID=54006446

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2015223579A Active AU2015223579B2 (en) 2014-02-28 2015-02-27 Aminocarbonylcarbamate compounds
AU2019236666A Active AU2019236666B2 (en) 2014-02-28 2019-09-25 Aminocarbonylcarbamate compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2019236666A Active AU2019236666B2 (en) 2014-02-28 2019-09-25 Aminocarbonylcarbamate compounds

Country Status (15)

Country Link
US (4) US9403761B2 (enExample)
EP (2) EP3587394B1 (enExample)
JP (2) JP6452731B2 (enExample)
KR (2) KR102487051B1 (enExample)
CN (2) CN109627186B (enExample)
AR (1) AR099581A1 (enExample)
AU (2) AU2015223579B2 (enExample)
CA (1) CA2939835C (enExample)
CL (1) CL2016002165A1 (enExample)
ES (2) ES2759312T3 (enExample)
MX (2) MX2016010973A (enExample)
PL (1) PL3110792T3 (enExample)
RU (1) RU2688673C2 (enExample)
TW (2) TWI655179B (enExample)
WO (1) WO2015130121A1 (enExample)

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TWI655179B (zh) * 2014-02-28 2019-04-01 南韓商愛思開生物製藥股份有限公司 胺基羰基胺基甲酸酯化合物
US10888542B2 (en) * 2014-02-28 2021-01-12 Sk Biopharmaceuticals Co., Ltd. Aminocarbonylcarbamate compounds
CN121202730A (zh) * 2016-09-06 2025-12-26 爱尔兰贾兹制药有限公司 (r)-2-氨基-3-苯丙基氨基甲酸酯盐酸盐的制备方法、其组合物及用途
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
JP7074750B2 (ja) 2016-10-06 2022-05-24 ジャズ ファーマスティカルズ アイルランド リミテッド カルバモイルフェニルアラニノール化合物およびその使用
KR20200016889A (ko) 2017-06-02 2020-02-17 재즈 파마슈티칼즈 아일랜드 리미티드 과다 졸림증을 치료하기 위한 방법 및 조성물
CN111153863A (zh) * 2019-12-13 2020-05-15 浙江工业大学 一种合成动物用抗球虫药物妥曲珠利的方法
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function
KR102390194B1 (ko) 2020-08-03 2022-04-25 셀라이온바이오메드 주식회사 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물

Citations (1)

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CA2146755A1 (en) * 1992-10-28 1994-05-11 Kenji Takeda Novel 1,2-benzoisoxazole derivative or its salt and brain-protecting agent comprising the same
KR100197892B1 (ko) * 1994-09-09 1999-06-15 남창우 신규한 페닐알킬아미노 카바메이트 화합물과 그의 제조방법
US5756817C1 (en) 1995-02-11 2001-04-17 Sk Corp O-carbamoyl-phenylananinol compounds their pharmaceutically useful salts and process for preparing the same
KR0173862B1 (ko) * 1995-02-11 1999-04-01 조규향 O-카바모일-(d)-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법
KR0173863B1 (ko) 1995-04-10 1999-04-01 조규향 페닐에 치환체가 있는 o-카바모일-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법
JP2006527214A (ja) * 2003-06-12 2006-11-30 ノボ ノルディスク アクティーゼルスカブ パラ置換されたフェニルカルバメート
US20050080268A1 (en) 2003-10-08 2005-04-14 Yong-Moon Choi Process of preparing O-carbamoyl compounds in the presence of active amine group
US7897639B2 (en) * 2003-10-21 2011-03-01 Colucid Pharmaceuticals, Inc. Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents
RU2007119648A (ru) 2004-10-28 2008-12-10 СК Холдингз Ко. Способ лечения депрессии
US7598279B2 (en) * 2005-04-22 2009-10-06 Sk Holdings Co., Ltd. Neurotherapeutic azole compounds
PL1890684T3 (pl) * 2005-06-08 2014-05-30 Sk Biopharmaceuticals Co Ltd Leczenie zaburzeń snu i czuwania
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TW200820963A (en) * 2006-07-28 2008-05-16 Xenoport Inc Acyloxyalkyl carbamate prodrugs of α-amino acids, methods of synthesis and use
CN101631770A (zh) * 2007-02-02 2010-01-20 科露西德医药品公司 抑制胆碱酯酶的化合物
AU2010270971B2 (en) 2009-06-22 2015-08-20 Sk Biopharmaceuticals Co., Ltd. Methods for treating or preventing fatigue
EP2496227B1 (en) 2009-11-06 2019-05-22 SK Biopharmaceuticals Co., Ltd. Methods for treating fibromyalgia syndrome
ES2447295T3 (es) * 2009-11-06 2014-03-11 Sk Biopharmaceuticals Co., Ltd. Métodos para el tratamiento del trastorno de déficit de atención/hiperactividad
US9610274B2 (en) * 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
US8623913B2 (en) * 2010-06-30 2014-01-07 Sk Biopharmaceuticals Co., Ltd. Methods for treating restless legs syndrome
DK3021838T3 (da) * 2013-07-18 2020-08-24 Jazz Pharmaceuticals Ireland Ltd Behandling af fedme
TWI655179B (zh) * 2014-02-28 2019-04-01 南韓商愛思開生物製藥股份有限公司 胺基羰基胺基甲酸酯化合物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102695502A (zh) * 2009-06-26 2012-09-26 爱思开生物制药株式会社 用于治疗药瘾和改善药瘾相关行为的组合物

Also Published As

Publication number Publication date
US9833432B2 (en) 2017-12-05
AU2015223579A1 (en) 2016-08-25
AU2019236666B2 (en) 2021-03-25
RU2019113158A (ru) 2019-06-25
EP3110792B1 (en) 2019-09-04
JP2017512211A (ja) 2017-05-18
KR20210124520A (ko) 2021-10-14
MX2016010973A (es) 2016-11-29
RU2016136193A (ru) 2018-03-30
ES2968840T3 (es) 2024-05-14
TWI655179B (zh) 2019-04-01
CN106458866B (zh) 2018-12-07
JP6452731B2 (ja) 2019-01-16
EP3587394B1 (en) 2023-11-01
US20160303067A1 (en) 2016-10-20
EP3110792A1 (en) 2017-01-04
MX387796B (es) 2025-03-19
JP2019059764A (ja) 2019-04-18
EP3110792A4 (en) 2017-09-27
CA2939835C (en) 2022-11-01
TW201920086A (zh) 2019-06-01
CN106458866A (zh) 2017-02-22
CN109627186B (zh) 2021-10-29
CL2016002165A1 (es) 2017-06-09
US10485781B2 (en) 2019-11-26
CA2939835A1 (en) 2015-09-03
US10314808B2 (en) 2019-06-11
AU2019236666A1 (en) 2019-10-17
ES2759312T3 (es) 2020-05-08
US20190247356A1 (en) 2019-08-15
WO2015130121A1 (en) 2015-09-03
PL3110792T3 (pl) 2020-02-28
US20180085337A1 (en) 2018-03-29
RU2688673C2 (ru) 2019-05-22
KR102309903B1 (ko) 2021-10-06
US20150246874A1 (en) 2015-09-03
TWI698415B (zh) 2020-07-11
KR20160126988A (ko) 2016-11-02
RU2016136193A3 (enExample) 2018-10-29
CN109627186A (zh) 2019-04-16
AR099581A1 (es) 2016-08-03
TW201623224A (zh) 2016-07-01
KR102487051B1 (ko) 2023-01-09
MX2020003020A (es) 2021-11-11
EP3587394A1 (en) 2020-01-01
JP6595078B2 (ja) 2019-10-23
US9403761B2 (en) 2016-08-02

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