ES2784685T3 - Productos conjugados de anticuerpo-fármaco específicos de AXL para el tratamiento del cáncer - Google Patents
Productos conjugados de anticuerpo-fármaco específicos de AXL para el tratamiento del cáncer Download PDFInfo
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- ES2784685T3 ES2784685T3 ES16739079T ES16739079T ES2784685T3 ES 2784685 T3 ES2784685 T3 ES 2784685T3 ES 16739079 T ES16739079 T ES 16739079T ES 16739079 T ES16739079 T ES 16739079T ES 2784685 T3 ES2784685 T3 ES 2784685T3
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- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
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RS60012B1 (sr) | 2014-07-11 | 2020-04-30 | Genmab As | Antitela koja vezuju axl |
CN108368171A (zh) * | 2015-07-10 | 2018-08-03 | 根马布股份公司 | 用于癌症治疗的axl特异性抗体-药物缀合物 |
EP3464275B1 (en) | 2016-05-26 | 2024-05-08 | Recurium IP Holdings, LLC | Egfr inhibitor compounds |
US20190233522A1 (en) | 2016-07-08 | 2019-08-01 | Genmab A/S | New dosage regimens for antibody drug conjugates based on anti-axl antibodies |
US10973829B2 (en) | 2016-09-19 | 2021-04-13 | Novartis Ag | Therapeutic uses of a C-RAF inhibitor |
AU2018209164B2 (en) | 2017-01-17 | 2021-11-04 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
TWI798218B (zh) | 2017-05-02 | 2023-04-11 | 瑞士商諾華公司 | 組合療法 |
EP3679159A1 (en) | 2017-09-08 | 2020-07-15 | H. Hoffnabb-La Roche Ag | Diagnostic and therapeutic methods for cancer |
SG11202002331QA (en) | 2017-09-13 | 2020-04-29 | Nat Res Council Canada | Axl-specific antibodies and uses thereof |
CN112218895A (zh) * | 2018-04-10 | 2021-01-12 | 健玛保 | 用于癌症治疗的axl特异性抗体 |
CN110483639A (zh) * | 2018-05-15 | 2019-11-22 | 复旦大学 | 靶向axl的抗体及抗体-药物偶联物及其制备方法和用途 |
CN110540592B (zh) * | 2018-05-29 | 2022-08-09 | 杭州尚健生物技术有限公司 | 结合axl蛋白的抗体及其应用 |
JP2022502411A (ja) * | 2018-09-26 | 2022-01-11 | ゲンマブ エー/エス | 非小細胞肺がんの処置のためのaxl特異的抗体 |
SG11202109932WA (en) * | 2019-03-20 | 2021-10-28 | Imcheck Therapeutics Sas | Antibodies having specificity for btn2 and uses thereof |
US20220177593A1 (en) * | 2019-03-29 | 2022-06-09 | Celldex Therapeutics, Inc. | Anti-axl antibodies and methods of use thereof |
WO2021154156A1 (en) * | 2020-01-31 | 2021-08-05 | Agency For Science, Technology And Research | Anti-axl antibody and uses thereof |
US11807688B2 (en) | 2020-02-28 | 2023-11-07 | Les Laboratoires Servier | Anti-AXL antibodies and compositions |
JP2023525100A (ja) * | 2020-05-12 | 2023-06-14 | ノバルティス アーゲー | Craf阻害剤を含む治療的組み合わせ |
WO2022026807A2 (en) * | 2020-07-30 | 2022-02-03 | Albert Einstein College Of Medicine | Antibodies targeting sars-cov-2 and uses thereof |
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