ES2774016T3 - Anticuerpos anti-cd40 y usos de los mismos - Google Patents

Anticuerpos anti-cd40 y usos de los mismos Download PDF

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Publication number
ES2774016T3
ES2774016T3 ES16728520T ES16728520T ES2774016T3 ES 2774016 T3 ES2774016 T3 ES 2774016T3 ES 16728520 T ES16728520 T ES 16728520T ES 16728520 T ES16728520 T ES 16728520T ES 2774016 T3 ES2774016 T3 ES 2774016T3
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Prior art keywords
antibody
antibodies
amino acid
seq
antigen
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English (en)
Spanish (es)
Inventor
Lorenzo Benatuil
Maria Argiriadi
Bradford Mcrae
Chung-Ming Hsieh
David A Egan
John E Harlan
Russell A Judge
Rui Wang
Gillian A Kingsbury
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AbbVie Inc
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AbbVie Inc
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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    • G01N2333/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30 CD40 or CD95

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  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
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ES16728520T 2015-05-29 2016-05-27 Anticuerpos anti-cd40 y usos de los mismos Active ES2774016T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562168425P 2015-05-29 2015-05-29
PCT/US2016/034716 WO2016196314A1 (en) 2015-05-29 2016-05-27 Anti-cd40 antibodies and uses thereof

Publications (1)

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ES2774016T3 true ES2774016T3 (es) 2020-07-16

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ES16728520T Active ES2774016T3 (es) 2015-05-29 2016-05-27 Anticuerpos anti-cd40 y usos de los mismos

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US (3) US10174121B2 (OSRAM)
EP (3) EP4047022A1 (OSRAM)
JP (3) JP6518917B2 (OSRAM)
KR (2) KR102661078B1 (OSRAM)
CN (2) CN107810198B (OSRAM)
AR (1) AR104809A1 (OSRAM)
AU (2) AU2016270640B2 (OSRAM)
CA (1) CA2987051A1 (OSRAM)
CL (1) CL2017003007A1 (OSRAM)
CO (1) CO2017012286A2 (OSRAM)
CR (1) CR20170592A (OSRAM)
CY (1) CY1122593T1 (OSRAM)
DK (1) DK3303395T3 (OSRAM)
DO (1) DOP2017000273A (OSRAM)
EC (1) ECSP17085333A (OSRAM)
ES (1) ES2774016T3 (OSRAM)
HR (1) HRP20200262T1 (OSRAM)
HU (1) HUE048284T2 (OSRAM)
IL (1) IL255961B (OSRAM)
LT (1) LT3303395T (OSRAM)
MX (1) MX392748B (OSRAM)
PE (1) PE20180193A1 (OSRAM)
PH (1) PH12017502161A1 (OSRAM)
PL (1) PL3303395T3 (OSRAM)
PT (1) PT3303395T (OSRAM)
RS (1) RS59935B1 (OSRAM)
RU (1) RU2715597C2 (OSRAM)
SI (1) SI3303395T1 (OSRAM)
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