ES2705698T3 - Terapia de combinación para el tratamiento del cáncer que comprende eribulina y lenvatinib - Google Patents

Terapia de combinación para el tratamiento del cáncer que comprende eribulina y lenvatinib Download PDF

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Publication number
ES2705698T3
ES2705698T3 ES14739971T ES14739971T ES2705698T3 ES 2705698 T3 ES2705698 T3 ES 2705698T3 ES 14739971 T ES14739971 T ES 14739971T ES 14739971 T ES14739971 T ES 14739971T ES 2705698 T3 ES2705698 T3 ES 2705698T3
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Spain
Prior art keywords
cancer
pharmaceutically acceptable
acceptable salt
eribulin
lenvatinib
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ES14739971T
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English (en)
Spanish (es)
Inventor
Kenichi Nomoto
Jiayi Wu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai R&D Management Co Ltd
Original Assignee
Eisai R&D Management Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dermatology (AREA)
ES14739971T 2013-06-26 2014-06-26 Terapia de combinación para el tratamiento del cáncer que comprende eribulina y lenvatinib Active ES2705698T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361839542P 2013-06-26 2013-06-26
PCT/JP2014/067723 WO2014208774A1 (en) 2013-06-26 2014-06-26 Use of eribulin and lenvatinib as combination therapy for treatment of cancer

Publications (1)

Publication Number Publication Date
ES2705698T3 true ES2705698T3 (es) 2019-03-26

Family

ID=51210708

Family Applications (1)

Application Number Title Priority Date Filing Date
ES14739971T Active ES2705698T3 (es) 2013-06-26 2014-06-26 Terapia de combinación para el tratamiento del cáncer que comprende eribulina y lenvatinib

Country Status (12)

Country Link
US (1) US9549922B2 (enExample)
EP (1) EP3013335B1 (enExample)
JP (1) JP6404242B2 (enExample)
KR (1) KR102265952B1 (enExample)
CN (1) CN105338977B (enExample)
AU (1) AU2014299699B2 (enExample)
BR (1) BR112015029386B1 (enExample)
CA (1) CA2915005C (enExample)
ES (1) ES2705698T3 (enExample)
IL (1) IL242386B (enExample)
RU (1) RU2672585C2 (enExample)
WO (1) WO2014208774A1 (enExample)

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KR20170122810A (ko) 2015-03-04 2017-11-06 머크 샤프 앤드 돔 코포레이션 암을 치료하기 위한 pd-1 길항제 및 에리불린의 조합
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US10865212B2 (en) 2017-01-02 2020-12-15 Yonsung Fine Chemical Co.. Ltd. Intermediate for preparing eribulin mesylate and process for preparing the same
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EP4384550A4 (en) * 2021-08-10 2025-06-18 Merck Sharp & Dohme LLC THERAPEUTIC COMBINATION WITH A TIGIT ANTAGONIST, A PD-1 ANTAGONIST AND LENVATINIB

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Also Published As

Publication number Publication date
KR102265952B1 (ko) 2021-06-16
BR112015029386B1 (pt) 2023-11-14
US20150005343A1 (en) 2015-01-01
US9549922B2 (en) 2017-01-24
BR112015029386A2 (pt) 2017-07-25
EP3013335A1 (en) 2016-05-04
RU2672585C2 (ru) 2018-11-16
JP2016528162A (ja) 2016-09-15
AU2014299699A1 (en) 2015-12-10
BR112015029386A8 (pt) 2020-03-17
CN105338977B (zh) 2018-10-16
EP3013335B1 (en) 2018-11-07
IL242386B (en) 2019-06-30
WO2014208774A1 (en) 2014-12-31
CA2915005A1 (en) 2014-12-31
CN105338977A (zh) 2016-02-17
KR20160023816A (ko) 2016-03-03
CA2915005C (en) 2021-12-28
JP6404242B2 (ja) 2018-10-10
AU2014299699B2 (en) 2019-10-10
RU2016102158A (ru) 2017-07-31

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