JP6404242B2 - がんの治療のための併用療法としてのエリブリンおよびレンバチニブの使用 - Google Patents

がんの治療のための併用療法としてのエリブリンおよびレンバチニブの使用 Download PDF

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JP6404242B2
JP6404242B2 JP2015562231A JP2015562231A JP6404242B2 JP 6404242 B2 JP6404242 B2 JP 6404242B2 JP 2015562231 A JP2015562231 A JP 2015562231A JP 2015562231 A JP2015562231 A JP 2015562231A JP 6404242 B2 JP6404242 B2 JP 6404242B2
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cancer
pharmaceutically acceptable
acceptable salt
eribulin
lenvatinib
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JP2016528162A5 (enExample
JP2016528162A (ja
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野本　研一
研一 野本
ウ，ジアイ
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Eisai R&D Management Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dermatology (AREA)
JP2015562231A 2013-06-26 2014-06-26 がんの治療のための併用療法としてのエリブリンおよびレンバチニブの使用 Active JP6404242B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361839542P 2013-06-26 2013-06-26
US61/839,542 2013-06-26
PCT/JP2014/067723 WO2014208774A1 (en) 2013-06-26 2014-06-26 Use of eribulin and lenvatinib as combination therapy for treatment of cancer

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JP2016528162A JP2016528162A (ja) 2016-09-15
JP2016528162A5 JP2016528162A5 (enExample) 2017-08-03
JP6404242B2 true JP6404242B2 (ja) 2018-10-10

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US (1) US9549922B2 (enExample)
EP (1) EP3013335B1 (enExample)
JP (1) JP6404242B2 (enExample)
KR (1) KR102265952B1 (enExample)
CN (1) CN105338977B (enExample)
AU (1) AU2014299699B2 (enExample)
BR (1) BR112015029386B1 (enExample)
CA (1) CA2915005C (enExample)
ES (1) ES2705698T3 (enExample)
IL (1) IL242386B (enExample)
RU (1) RU2672585C2 (enExample)
WO (1) WO2014208774A1 (enExample)

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Also Published As

Publication number Publication date
ES2705698T3 (es) 2019-03-26
WO2014208774A1 (en) 2014-12-31
CN105338977B (zh) 2018-10-16
US20150005343A1 (en) 2015-01-01
KR20160023816A (ko) 2016-03-03
RU2672585C2 (ru) 2018-11-16
CN105338977A (zh) 2016-02-17
CA2915005C (en) 2021-12-28
RU2016102158A (ru) 2017-07-31
BR112015029386B1 (pt) 2023-11-14
JP2016528162A (ja) 2016-09-15
CA2915005A1 (en) 2014-12-31
US9549922B2 (en) 2017-01-24
IL242386B (en) 2019-06-30
AU2014299699A1 (en) 2015-12-10
BR112015029386A2 (pt) 2017-07-25
KR102265952B1 (ko) 2021-06-16
AU2014299699B2 (en) 2019-10-10
BR112015029386A8 (pt) 2020-03-17
EP3013335B1 (en) 2018-11-07
EP3013335A1 (en) 2016-05-04

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