ES2660461T3 - Composición farmacéutica que comprende (1R,4R)-6'-fluor-N,N-dimetil-4-fenil-4',9'-dihidro-3'H-espiro[ciclohexan-1,1'-pirano[3,4,b]indol]-4-amina y duloxetina - Google Patents

Composición farmacéutica que comprende (1R,4R)-6'-fluor-N,N-dimetil-4-fenil-4',9'-dihidro-3'H-espiro[ciclohexan-1,1'-pirano[3,4,b]indol]-4-amina y duloxetina Download PDF

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Publication number
ES2660461T3
ES2660461T3 ES13723003.3T ES13723003T ES2660461T3 ES 2660461 T3 ES2660461 T3 ES 2660461T3 ES 13723003 T ES13723003 T ES 13723003T ES 2660461 T3 ES2660461 T3 ES 2660461T3
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pharmacologically active
active ingredient
pharmaceutical dosage
dosage form
pain
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ES13723003.3T
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English (en)
Spanish (es)
Inventor
Stefanie Frosch
Klaus Linz
Thomas Christoph
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Gruenenthal GmbH
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Gruenenthal GmbH
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES13723003.3T 2012-05-18 2013-05-16 Composición farmacéutica que comprende (1R,4R)-6'-fluor-N,N-dimetil-4-fenil-4',9'-dihidro-3'H-espiro[ciclohexan-1,1'-pirano[3,4,b]indol]-4-amina y duloxetina Active ES2660461T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12003937 2012-05-18
EP12003937 2012-05-18
PCT/EP2013/001464 WO2013170965A1 (en) 2012-05-18 2013-05-16 Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and antidepressants

Publications (1)

Publication Number Publication Date
ES2660461T3 true ES2660461T3 (es) 2018-03-22

Family

ID=48446243

Family Applications (1)

Application Number Title Priority Date Filing Date
ES13723003.3T Active ES2660461T3 (es) 2012-05-18 2013-05-16 Composición farmacéutica que comprende (1R,4R)-6'-fluor-N,N-dimetil-4-fenil-4',9'-dihidro-3'H-espiro[ciclohexan-1,1'-pirano[3,4,b]indol]-4-amina y duloxetina

Country Status (22)

Country Link
US (2) US20130310385A1 (enExample)
EP (1) EP2849744B1 (enExample)
JP (1) JP6116672B2 (enExample)
CN (1) CN104271131A (enExample)
AU (1) AU2013262071B2 (enExample)
BR (1) BR112014028562A2 (enExample)
CA (1) CA2873634A1 (enExample)
CY (1) CY1119825T1 (enExample)
DK (1) DK2849744T3 (enExample)
EA (1) EA027268B1 (enExample)
ES (1) ES2660461T3 (enExample)
HR (1) HRP20171922T1 (enExample)
HU (1) HUE037746T2 (enExample)
IL (1) IL235657B (enExample)
LT (1) LT2849744T (enExample)
MX (1) MX354684B (enExample)
NO (1) NO2849744T3 (enExample)
PL (1) PL2849744T3 (enExample)
PT (1) PT2849744T (enExample)
RS (1) RS56856B1 (enExample)
SI (1) SI2849744T1 (enExample)
WO (1) WO2013170965A1 (enExample)

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RU2246418C1 (ru) * 2003-06-19 2005-02-20 Общество с ограниченной ответственностью "ТехноМастер" Усилитель щитка передка кузова легкового автомобиля
CA2974578C (en) 2015-01-23 2020-11-17 Grunenthal Gmbh Cebranopadol for treating pain in subjects with impaired hepatic and/or impaired renal function
EP3870292A4 (en) 2018-10-26 2022-11-09 The Research Foundation for The State University of New York COMBINATION OF SEROTONIN-SPECIFIC RESUPPUT INHIBITOR AND SEROTONIN 1A RECEPTOR PARTIAL AGONIST TO REDUCE L-DOPA-INDUCED DYSKINESIA

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Also Published As

Publication number Publication date
JP2015520154A (ja) 2015-07-16
EP2849744A1 (en) 2015-03-25
JP6116672B2 (ja) 2017-04-19
IL235657B (en) 2018-08-30
HRP20171922T1 (hr) 2018-02-09
US20130310385A1 (en) 2013-11-21
US20170065560A1 (en) 2017-03-09
CY1119825T1 (el) 2018-06-27
HUE037746T2 (hu) 2018-09-28
PT2849744T (pt) 2018-02-28
HK1204944A1 (en) 2015-12-11
AU2013262071B2 (en) 2018-01-18
LT2849744T (lt) 2018-02-26
PL2849744T3 (pl) 2018-06-29
US10328055B2 (en) 2019-06-25
EA201401269A1 (ru) 2016-05-31
WO2013170965A1 (en) 2013-11-21
CN104271131A (zh) 2015-01-07
RS56856B1 (sr) 2018-04-30
NO2849744T3 (enExample) 2018-04-21
EA027268B1 (ru) 2017-07-31
CA2873634A1 (en) 2013-11-21
IL235657A0 (en) 2015-01-29
AU2013262071A1 (en) 2015-01-22
BR112014028562A2 (pt) 2017-06-27
EP2849744B1 (en) 2017-11-22
MX2014012859A (es) 2015-01-19
SI2849744T1 (en) 2018-01-31
DK2849744T3 (en) 2018-01-22
MX354684B (es) 2018-03-15

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