ES2659270T3 - Anticuerpo modificado, conjugado de anticuerpo y proceso de preparación de los mismos - Google Patents

Anticuerpo modificado, conjugado de anticuerpo y proceso de preparación de los mismos Download PDF

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Publication number
ES2659270T3
ES2659270T3 ES13786322.1T ES13786322T ES2659270T3 ES 2659270 T3 ES2659270 T3 ES 2659270T3 ES 13786322 T ES13786322 T ES 13786322T ES 2659270 T3 ES2659270 T3 ES 2659270T3
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antibody
group
glcnac
hetero
conjugate
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Spanish (es)
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Floris Louis Van Delft
Remon VAN GEEL
Maria Antonia WIJDEVEN
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Synaffix BV
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Synaffix BV
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    • A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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