ES2643640T3 - Agentes para tratamiento de enfermedad - Google Patents

Agentes para tratamiento de enfermedad Download PDF

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Publication number
ES2643640T3
ES2643640T3 ES10782326.2T ES10782326T ES2643640T3 ES 2643640 T3 ES2643640 T3 ES 2643640T3 ES 10782326 T ES10782326 T ES 10782326T ES 2643640 T3 ES2643640 T3 ES 2643640T3
Authority
ES
Spain
Prior art keywords
antibody
peptide
heavy chain
lymphocytes
light chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES10782326.2T
Other languages
English (en)
Spanish (es)
Inventor
Frank Osterroth
Christoph Uherek
Christoph Bruecher
Benjamin Daelken
André ENGLING
Chantal Zuber
Niklas Czeloth
Holger Wallmeier
Kirsten VÖLP
Gregor Schulz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biotest AG
Original Assignee
Biotest AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotest AG filed Critical Biotest AG
Application granted granted Critical
Publication of ES2643640T3 publication Critical patent/ES2643640T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70514—CD4

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ES10782326.2T 2009-11-30 2010-11-30 Agentes para tratamiento de enfermedad Active ES2643640T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0920944 2009-11-30
GBGB0920944.6A GB0920944D0 (en) 2009-11-30 2009-11-30 Agents for treating disease
PCT/EP2010/068579 WO2011064407A1 (en) 2009-11-30 2010-11-30 Agents for treating disease

Publications (1)

Publication Number Publication Date
ES2643640T3 true ES2643640T3 (es) 2017-11-23

Family

ID=41572903

Family Applications (1)

Application Number Title Priority Date Filing Date
ES10782326.2T Active ES2643640T3 (es) 2009-11-30 2010-11-30 Agentes para tratamiento de enfermedad

Country Status (17)

Country Link
US (1) US9995733B2 (enExample)
EP (1) EP2470902B1 (enExample)
JP (1) JP5959438B2 (enExample)
KR (1) KR101872746B1 (enExample)
CN (1) CN102687010B (enExample)
AU (1) AU2010323045B2 (enExample)
BR (1) BR112012012911A8 (enExample)
CA (1) CA2781836A1 (enExample)
ES (1) ES2643640T3 (enExample)
GB (1) GB0920944D0 (enExample)
IL (1) IL219956B (enExample)
MX (1) MX347247B (enExample)
NZ (1) NZ600889A (enExample)
RU (1) RU2598719C2 (enExample)
SG (2) SG10201407938TA (enExample)
WO (1) WO2011064407A1 (enExample)
ZA (1) ZA201204845B (enExample)

Families Citing this family (12)

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US20170232084A1 (en) 2013-04-26 2017-08-17 Enzo Biochem Inc. Immune modulation for the treatment of age-related macular degeneration
US20140322188A1 (en) 2013-04-26 2014-10-30 Enzo Biochem, Inc. Tolerizing treatments for autoimmune disease
GB201413899D0 (en) 2014-08-06 2014-09-17 Johnson Matthey Plc Catalyst and use therof
WO2016171980A1 (en) * 2015-04-24 2016-10-27 Bristol-Myers Squibb Company Polypeptides targeting hiv fusion
US20180126021A1 (en) * 2016-11-04 2018-05-10 Covidien Lp Sterilization system and method
CA3182945A1 (en) * 2020-07-06 2022-01-13 Israel Vlodavsky Heparanase-neutralizing a54 monoclonal antibody
GB202017681D0 (en) 2020-11-09 2020-12-23 T Balance Therapeutics Gmbh Anti-CD4 antibody or fragment thereof for medical use
AU2022492449A1 (en) * 2022-12-29 2025-07-10 Chang Gung Memorial Hospital, Linkou Antibodies specific to transmembrane and coiled-coil domain family 3 and uses thereof
GB202401501D0 (en) 2024-02-05 2024-03-20 T Balance Therapeutics Gmbh Medical use of regulatory t cell activator
GB202409801D0 (en) 2024-07-05 2024-08-21 T Balance Therapeutics Gmbh Products for use in the treatment and prevention of allergy and associated lung conditions/diseases

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Also Published As

Publication number Publication date
CN102687010B (zh) 2016-06-15
AU2010323045B2 (en) 2015-09-24
CN102687010A (zh) 2012-09-19
KR20120102733A (ko) 2012-09-18
JP2013511996A (ja) 2013-04-11
MX347247B (es) 2017-04-17
IL219956B (en) 2019-07-31
ZA201204845B (en) 2016-06-29
RU2598719C2 (ru) 2016-09-27
SG10201407938TA (en) 2015-01-29
GB0920944D0 (en) 2010-01-13
MX2012006199A (es) 2012-06-19
NZ600889A (en) 2015-09-25
US9995733B2 (en) 2018-06-12
KR101872746B1 (ko) 2018-06-29
EP2470902A1 (en) 2012-07-04
BR112012012911A2 (pt) 2016-10-25
JP5959438B2 (ja) 2016-08-02
SG181117A1 (en) 2012-07-30
US20130004513A1 (en) 2013-01-03
CA2781836A1 (en) 2011-06-03
EP2470902B1 (en) 2017-07-19
BR112012012911A8 (pt) 2018-02-27
WO2011064407A1 (en) 2011-06-03
AU2010323045A1 (en) 2012-07-19
RU2012127378A (ru) 2014-01-10
IL219956A0 (en) 2012-07-31

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