ES2536558T3 - Sal citrato de 11-(2-pirrolidin-1-il-etoxi)-14,19-dioxa-5,7,26-triaza-tetraciclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-deceno - Google Patents
Sal citrato de 11-(2-pirrolidin-1-il-etoxi)-14,19-dioxa-5,7,26-triaza-tetraciclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-deceno Download PDFInfo
- Publication number
- ES2536558T3 ES2536558T3 ES09788621.2T ES09788621T ES2536558T3 ES 2536558 T3 ES2536558 T3 ES 2536558T3 ES 09788621 T ES09788621 T ES 09788621T ES 2536558 T3 ES2536558 T3 ES 2536558T3
- Authority
- ES
- Spain
- Prior art keywords
- tetracycle
- heptacosa
- triaza
- dioxa
- decene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- -1 2-pyrrolidin-1-yl-ethoxy Chemical group 0.000 title abstract 2
- 150000001860 citric acid derivatives Chemical class 0.000 title abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/22—Tricarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D201/00—Preparation, separation, purification or stabilisation of unsubstituted lactams
- C07D201/02—Preparation of lactams
- C07D201/10—Preparation of lactams from cycloaliphatic compounds by simultaneous nitrosylation and rearrangement
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US121668P | 1999-02-25 | ||
| US12166808P | 2008-12-11 | 2008-12-11 | |
| PCT/SG2009/000473 WO2010068181A1 (en) | 2008-12-11 | 2009-12-09 | 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6)1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27)j16,21,23-decaene citrate salt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2536558T3 true ES2536558T3 (es) | 2015-05-26 |
Family
ID=41666397
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09788621.2T Active ES2536558T3 (es) | 2008-12-11 | 2009-12-09 | Sal citrato de 11-(2-pirrolidin-1-il-etoxi)-14,19-dioxa-5,7,26-triaza-tetraciclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-deceno |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US8980873B2 (enExample) |
| EP (1) | EP2376499B1 (enExample) |
| JP (1) | JP5669748B2 (enExample) |
| KR (1) | KR101729918B1 (enExample) |
| CN (1) | CN102282148B (enExample) |
| AR (2) | AR074724A1 (enExample) |
| AU (1) | AU2009325147B2 (enExample) |
| BR (1) | BRPI0922736B1 (enExample) |
| CA (1) | CA2746058C (enExample) |
| DK (1) | DK2376499T3 (enExample) |
| ES (1) | ES2536558T3 (enExample) |
| HR (1) | HRP20150428T1 (enExample) |
| IL (3) | IL213418A0 (enExample) |
| MX (1) | MX2011006206A (enExample) |
| MY (1) | MY160005A (enExample) |
| NZ (1) | NZ593223A (enExample) |
| PL (1) | PL2376499T3 (enExample) |
| PT (1) | PT2376499E (enExample) |
| RU (1) | RU2527970C2 (enExample) |
| SG (1) | SG171907A1 (enExample) |
| TW (1) | TWI449705B (enExample) |
| WO (1) | WO2010068181A1 (enExample) |
| ZA (1) | ZA201104032B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG171907A1 (en) | 2008-12-11 | 2011-07-28 | S Bio Pte Ltd | 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6)1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27)j16,21,23-decaene citrate salt |
| HRP20150413T8 (xx) * | 2008-12-11 | 2015-08-14 | Cti Biopharma Corp. | 11-(2-pirolidin-1-il-etoksi)-14,19-dioksa-5,7,26-triaza-tetraciklo[19.31.1(2,6).1(8,12)]heptakoza-1(25),2(26),3,5,8,10,12(27),16,21,23-dekaen maleatna sol |
| JP5925381B2 (ja) | 2012-04-13 | 2016-05-25 | ▲連雲▼港金康和信▲薬業▼有限公司Ｌｉａｎｙｕｎｇａｎｇ Ｊｉｎｋａｎｇ Ｈｅｘｉｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．， Ｌｔｄ． | 化合物［４−（２−アミノ−１０−メチル−４−オキソ−６，７，８，９−テトラヒドロ−４ａ，７−エピミノピリミド［４，５−ｂ］［１，４］ジアゼピン−５（４Ｈ）−イル）ベンゾイル］−グルタメート及びその製造 |
| CN105061467B (zh) * | 2015-08-28 | 2017-08-25 | 苏州立新制药有限公司 | 一种帕克替尼的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5728536A (en) | 1993-07-29 | 1998-03-17 | St. Jude Children's Research Hospital | Jak kinases and regulation of Cytokine signal transduction |
| US6136595A (en) | 1993-07-29 | 2000-10-24 | St. Jude Children's Research Hospital | Jak kinases and regulations of cytokine signal transduction |
| EP1390366B1 (en) * | 2001-05-14 | 2005-08-31 | Pfizer Products Inc. | The citrate salt of 5,8,14,-triazatetracyclo(10.3.1.02,11.04,9)-hexadeca-2(11),3,5,7,9-pentaene |
| US6433018B1 (en) | 2001-08-31 | 2002-08-13 | The Research Foundation Of State University Of New York | Method for reducing hypertrophy and ischemia |
| CA2468705A1 (en) * | 2001-11-29 | 2003-06-05 | Pfizer Products Inc. | Succinic acid salts of 5,8,14-triazatetracyclo'10.3.1.0<2,11>.0<4,9>-hexadeca-2(11),3,5,7,9-pentaene and pharmaceutical compositions thereof |
| ES2506040T3 (es) | 2005-11-16 | 2014-10-13 | Cti Biopharma Corp. | Derivados de pirimidina ligados a oxígeno |
| SG171907A1 (en) | 2008-12-11 | 2011-07-28 | S Bio Pte Ltd | 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6)1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27)j16,21,23-decaene citrate salt |
-
2009
- 2009-12-09 SG SG2011040060A patent/SG171907A1/en unknown
- 2009-12-09 WO PCT/SG2009/000473 patent/WO2010068181A1/en not_active Ceased
- 2009-12-09 MY MYPI2011002647A patent/MY160005A/en unknown
- 2009-12-09 MX MX2011006206A patent/MX2011006206A/es active IP Right Grant
- 2009-12-09 BR BRPI0922736-9A patent/BRPI0922736B1/pt active IP Right Grant
- 2009-12-09 CA CA2746058A patent/CA2746058C/en active Active
- 2009-12-09 PT PT97886212T patent/PT2376499E/pt unknown
- 2009-12-09 DK DK09788621T patent/DK2376499T3/en active
- 2009-12-09 AU AU2009325147A patent/AU2009325147B2/en active Active
- 2009-12-09 US US13/133,297 patent/US8980873B2/en active Active
- 2009-12-09 EP EP09788621.2A patent/EP2376499B1/en active Active
- 2009-12-09 KR KR1020117015738A patent/KR101729918B1/ko active Active
- 2009-12-09 JP JP2011540664A patent/JP5669748B2/ja active Active
- 2009-12-09 NZ NZ593223A patent/NZ593223A/xx unknown
- 2009-12-09 HR HRP20150428TT patent/HRP20150428T1/hr unknown
- 2009-12-09 RU RU2011126173/04A patent/RU2527970C2/ru active
- 2009-12-09 ES ES09788621.2T patent/ES2536558T3/es active Active
- 2009-12-09 PL PL09788621T patent/PL2376499T3/pl unknown
- 2009-12-09 CN CN200980150325.5A patent/CN102282148B/zh active Active
- 2009-12-11 TW TW098142605A patent/TWI449705B/zh active
- 2009-12-11 AR ARP090104834A patent/AR074724A1/es not_active Application Discontinuation
-
2011
- 2011-05-31 ZA ZA2011/04032A patent/ZA201104032B/en unknown
- 2011-06-06 IL IL213418A patent/IL213418A0/en unknown
-
2015
- 2015-02-13 US US14/621,726 patent/US9624242B2/en active Active
-
2017
- 2017-01-26 IL IL250310A patent/IL250310A0/en unknown
-
2019
- 2019-03-20 AR ARP190100701A patent/AR114133A2/es unknown
-
2021
- 2021-12-26 IL IL289379A patent/IL289379A/en unknown
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