PL2376499T3 - Sól cytrynianowa 11-(2-pirrolidyn-1-yloetoksy)-14,19-dioksa-5,7,26-triazatetracyklo[19.3.1.1(2,6).1(8,12)]heptakosa-1(25),2(26),3,5,8,10,12(27),16,21,23-dekaenu - Google Patents
Sól cytrynianowa 11-(2-pirrolidyn-1-yloetoksy)-14,19-dioksa-5,7,26-triazatetracyklo[19.3.1.1(2,6).1(8,12)]heptakosa-1(25),2(26),3,5,8,10,12(27),16,21,23-dekaenuInfo
- Publication number
- PL2376499T3 PL2376499T3 PL09788621T PL09788621T PL2376499T3 PL 2376499 T3 PL2376499 T3 PL 2376499T3 PL 09788621 T PL09788621 T PL 09788621T PL 09788621 T PL09788621 T PL 09788621T PL 2376499 T3 PL2376499 T3 PL 2376499T3
- Authority
- PL
- Poland
- Prior art keywords
- heptacosa
- tetracyclo
- triaza
- dioxa
- pyrrolidin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/22—Tricarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D201/00—Preparation, separation, purification or stabilisation of unsubstituted lactams
- C07D201/02—Preparation of lactams
- C07D201/10—Preparation of lactams from cycloaliphatic compounds by simultaneous nitrosylation and rearrangement
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12166808P | 2008-12-11 | 2008-12-11 | |
| PCT/SG2009/000473 WO2010068181A1 (en) | 2008-12-11 | 2009-12-09 | 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6)1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27)j16,21,23-decaene citrate salt |
| EP09788621.2A EP2376499B1 (en) | 2008-12-11 | 2009-12-09 | 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6)1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene citrate salt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2376499T3 true PL2376499T3 (pl) | 2015-07-31 |
Family
ID=41666397
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09788621T PL2376499T3 (pl) | 2008-12-11 | 2009-12-09 | Sól cytrynianowa 11-(2-pirrolidyn-1-yloetoksy)-14,19-dioksa-5,7,26-triazatetracyklo[19.3.1.1(2,6).1(8,12)]heptakosa-1(25),2(26),3,5,8,10,12(27),16,21,23-dekaenu |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US8980873B2 (pl) |
| EP (1) | EP2376499B1 (pl) |
| JP (1) | JP5669748B2 (pl) |
| KR (1) | KR101729918B1 (pl) |
| CN (1) | CN102282148B (pl) |
| AR (2) | AR074724A1 (pl) |
| AU (1) | AU2009325147B2 (pl) |
| BR (1) | BRPI0922736B1 (pl) |
| CA (1) | CA2746058C (pl) |
| DK (1) | DK2376499T3 (pl) |
| ES (1) | ES2536558T3 (pl) |
| HK (1) | HK1161877A1 (pl) |
| HR (1) | HRP20150428T1 (pl) |
| IL (3) | IL213418A0 (pl) |
| MX (1) | MX2011006206A (pl) |
| MY (1) | MY160005A (pl) |
| NZ (1) | NZ593223A (pl) |
| PL (1) | PL2376499T3 (pl) |
| PT (1) | PT2376499E (pl) |
| RU (1) | RU2527970C2 (pl) |
| SG (1) | SG171907A1 (pl) |
| TW (1) | TWI449705B (pl) |
| WO (1) | WO2010068181A1 (pl) |
| ZA (1) | ZA201104032B (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2376499E (pt) | 2008-12-11 | 2015-06-03 | Cti Biopharma Corp | Sal citrato de 11-(2-pirrolidin-1-il-etoxi)-14,19-dioxa- 5,7,26-triaza-tetraciclo[19.3.1.1(2,6)1(8,12)]heptacosa- 1(25),2(26),3,5,8,10,1 (27),16,21,23-decaeno |
| DK2376500T3 (en) * | 2008-12-11 | 2015-05-04 | Cti Biopharma Corp | 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaenmaleatsalt |
| JP5925381B2 (ja) | 2012-04-13 | 2016-05-25 | ▲連雲▼港金康和信▲薬業▼有限公司Ｌｉａｎｙｕｎｇａｎｇ Ｊｉｎｋａｎｇ Ｈｅｘｉｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｃｏ．， Ｌｔｄ． | 化合物［４−（２−アミノ−１０−メチル−４−オキソ−６，７，８，９−テトラヒドロ−４ａ，７−エピミノピリミド［４，５−ｂ］［１，４］ジアゼピン−５（４Ｈ）−イル）ベンゾイル］−グルタメート及びその製造 |
| CN105061467B (zh) * | 2015-08-28 | 2017-08-25 | 苏州立新制药有限公司 | 一种帕克替尼的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5728536A (en) | 1993-07-29 | 1998-03-17 | St. Jude Children's Research Hospital | Jak kinases and regulation of Cytokine signal transduction |
| US6136595A (en) | 1993-07-29 | 2000-10-24 | St. Jude Children's Research Hospital | Jak kinases and regulations of cytokine signal transduction |
| OA12600A (en) * | 2001-05-14 | 2006-06-09 | Pfizer Prod Inc | The citrate salt of 5,8,14-triazatetracyclo 10.3.1.o2,11.o49)-hexadeca-2(11)3,5,7,9-pentaene and pharmaceutical compositions thereof. |
| US6433018B1 (en) | 2001-08-31 | 2002-08-13 | The Research Foundation Of State University Of New York | Method for reducing hypertrophy and ischemia |
| AU2002341327A1 (en) * | 2001-11-29 | 2003-06-10 | Pfizer Products Inc. | Succinic acid salts of 5,8,14-triazatetracyclo'10.3.1.0<2,11>.0<4,9>-hexadeca-2(11),3,5,7,9-pentaene and pharmaceutical compositions thereof |
| KR101499594B1 (ko) * | 2005-11-16 | 2015-03-09 | 씨티아이 바이오파마 코포레이션 | 산소가 결합된 피리미딘 유도체 |
| PT2376499E (pt) | 2008-12-11 | 2015-06-03 | Cti Biopharma Corp | Sal citrato de 11-(2-pirrolidin-1-il-etoxi)-14,19-dioxa- 5,7,26-triaza-tetraciclo[19.3.1.1(2,6)1(8,12)]heptacosa- 1(25),2(26),3,5,8,10,1 (27),16,21,23-decaeno |
-
2009
- 2009-12-09 PT PT97886212T patent/PT2376499E/pt unknown
- 2009-12-09 JP JP2011540664A patent/JP5669748B2/ja active Active
- 2009-12-09 NZ NZ593223A patent/NZ593223A/xx unknown
- 2009-12-09 CA CA2746058A patent/CA2746058C/en active Active
- 2009-12-09 RU RU2011126173/04A patent/RU2527970C2/ru active
- 2009-12-09 CN CN200980150325.5A patent/CN102282148B/zh active Active
- 2009-12-09 MX MX2011006206A patent/MX2011006206A/es active IP Right Grant
- 2009-12-09 KR KR1020117015738A patent/KR101729918B1/ko active IP Right Grant
- 2009-12-09 MY MYPI2011002647A patent/MY160005A/en unknown
- 2009-12-09 US US13/133,297 patent/US8980873B2/en active Active
- 2009-12-09 WO PCT/SG2009/000473 patent/WO2010068181A1/en active Application Filing
- 2009-12-09 AU AU2009325147A patent/AU2009325147B2/en active Active
- 2009-12-09 PL PL09788621T patent/PL2376499T3/pl unknown
- 2009-12-09 BR BRPI0922736-9A patent/BRPI0922736B1/pt active IP Right Grant
- 2009-12-09 ES ES09788621.2T patent/ES2536558T3/es active Active
- 2009-12-09 EP EP09788621.2A patent/EP2376499B1/en active Active
- 2009-12-09 SG SG2011040060A patent/SG171907A1/en unknown
- 2009-12-09 DK DK09788621T patent/DK2376499T3/en active
- 2009-12-11 TW TW098142605A patent/TWI449705B/zh active
- 2009-12-11 AR ARP090104834A patent/AR074724A1/es not_active Application Discontinuation
-
2011
- 2011-05-31 ZA ZA2011/04032A patent/ZA201104032B/en unknown
- 2011-06-06 IL IL213418A patent/IL213418A0/en unknown
-
2012
- 2012-03-08 HK HK12102375.7A patent/HK1161877A1/xx unknown
-
2015
- 2015-02-13 US US14/621,726 patent/US9624242B2/en active Active
- 2015-04-20 HR HRP20150428TT patent/HRP20150428T1/hr unknown
-
2017
- 2017-01-26 IL IL250310A patent/IL250310A0/en unknown
-
2019
- 2019-03-20 AR ARP190100701A patent/AR114133A2/es unknown
-
2021
- 2021-12-26 IL IL289379A patent/IL289379A/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUS1800031I1 (hu) | Dioxa-biciklo[3.2.1.]oktán-2,3,4-triol származékok | |
| IL289379A (en) | Citrate salt of 11-(2-pyrrolidin-1-yl-ethoxy)-19,14-dioxa-26,7,5-triaza-tetracyclo[1.1.3.19(6,2)1(12,8)]hepatacosa- 1(25),2(26),12,10,8,5,3(27)j23,21,16–Decan | |
| IL242665B (en) | Processes for preparing anti-tricyclo[3.2.2.0]non-6-ene-endo-8,endo-9-dicarboxylic acid anhydride | |
| IL206765A0 (en) | 4,5-dihydro-oxazol-2-yl-amine derivatives | |
| IL213787A0 (en) | Substituted 5,6-dihydro-6-phenylbenzo[f] isoquinolin-2-amine compounds | |
| PL2013208T3 (pl) | Pirydyno[3,4-B]pirazynowy | |
| IL188431A0 (en) | Process for preparing 3-arylmethylthio-and 3-heteroarylmethylthio-4,5-dihydro- | |
| HRP20150413T8 (en) | 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene maleate salt | |
| HK1178159A1 (en) | 9e-15-(2-pyrrolidin-1-yl-ethoxy)-7,12,25-trioxa-19,21,24-triaza- tetracyclo[18.3.1.1(2,5).1(14)18)]hexacosa-1(24),2,4,9,14,16,18(26),20,22- nonaene citrate salt 9e-15-(2--1--)-71225--192124-- [18311(25)1(1418)]-1(24)249141618(26)20 22- | |
| MX285136B (es) | Metodo de produccion de polieteramina. | |
| IL206666A0 (en) | N-PHENYLIMIDAZO[1,2-a]PYRIDINE-2- | |
| IL206668A0 (en) | N-PHENYLIMIDAZO[1,2-a]PYRIDINE-2- | |
| IL200166A0 (en) | New process for preparing 3-methyl-4-phenylisoxazolo[3,4-d]pyridazin-7(6h)-one | |
| IL187673A0 (en) | Process for preparing 3,3-diarylpropylamines | |
| HK1151801A1 (en) | 15,16-methylene-17-hydroxy-19-nor-21-carboxylic acid | |
| ZA201101961B (en) | Method for preparing 1,6:2,3-dianhydro-beta-d-mannopyranose | |
| TH0901005537B (th) | 11-(2-ไพร์โรลิดิน-1-อิล-เอทอกซี)-14,19-ไดออกซา-5,7,26-ไตรอะซา-เตตราไซโคล[19.3.1.1(2,6).1(8,12)]เฮปทาโคซา-1(25),2(26),3,5,8,10,12(27),16,21,23-เดคาอีน มาลีเอท ซอลท์ | |
| IL198203A0 (en) | Process for preparing 5-alkyl-7h-pyrrolo[2,3-d]pyrimidine-2-ols | |
| IL180493A (en) | Process for preparing 1-methoxymethyl-5,5-diphenylbarbituric acid | |
| PL392579A1 (pl) | Nowy związek 7,7-dimetylo-3,4-epoksy-8-oksabicyklo[4.3.0]nonan-9-on i sposób jego otrzymywania |