PL2454266T3 - Sól cytrynianowa 9E-15-(2-pirolidyn-1-ylo-etoksy)-7,12,25-trioksa-19,21,24-triaza-tetracyklo[18.3.1.1(2,5).1(14,18)]heksakoza-1(24),2,4,9,14,16,18(26),20,22-nonaenu - Google Patents
Sól cytrynianowa 9E-15-(2-pirolidyn-1-ylo-etoksy)-7,12,25-trioksa-19,21,24-triaza-tetracyklo[18.3.1.1(2,5).1(14,18)]heksakoza-1(24),2,4,9,14,16,18(26),20,22-nonaenuInfo
- Publication number
- PL2454266T3 PL2454266T3 PL10737645T PL10737645T PL2454266T3 PL 2454266 T3 PL2454266 T3 PL 2454266T3 PL 10737645 T PL10737645 T PL 10737645T PL 10737645 T PL10737645 T PL 10737645T PL 2454266 T3 PL2454266 T3 PL 2454266T3
- Authority
- PL
- Poland
- Prior art keywords
- nonaene
- hexacosa
- trioxa
- tetracyclo
- triaza
- Prior art date
Links
- 150000001860 citric acid derivatives Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22560909P | 2009-07-15 | 2009-07-15 | |
| PCT/SG2010/000265 WO2011008172A1 (en) | 2009-07-15 | 2010-07-14 | 9e-15-(2-pyrrolidin-1-yl-ethoxy)-7,12,25-trioxa-19,21,24-triaza- tetracyclo[18.3.1.1(2,5).1(14)18)]hexacosa-1(24),2,4,9,14,16,18(26),20,22-nonaene citrate salt |
| EP10737645.1A EP2454266B1 (en) | 2009-07-15 | 2010-07-14 | 9e-15-(2-pyrrolidin-1-yl-ethoxy)-7,12,25-trioxa-19,21,24-triaza- tetracyclo[18.3.1.1(2,5).1(14)18)]hexacosa-1(24),2,4,9,14,16,18(26),20,22-nonaene citrate salt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2454266T3 true PL2454266T3 (pl) | 2014-01-31 |
Family
ID=42790728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10737645T PL2454266T3 (pl) | 2009-07-15 | 2010-07-14 | Sól cytrynianowa 9E-15-(2-pirolidyn-1-ylo-etoksy)-7,12,25-trioksa-19,21,24-triaza-tetracyklo[18.3.1.1(2,5).1(14,18)]heksakoza-1(24),2,4,9,14,16,18(26),20,22-nonaenu |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9062074B2 (pl) |
| EP (1) | EP2454266B1 (pl) |
| JP (2) | JP6013911B2 (pl) |
| CN (1) | CN102762577B (pl) |
| AR (2) | AR077483A1 (pl) |
| BR (1) | BR112012000750B1 (pl) |
| CA (1) | CA2768210C (pl) |
| DK (1) | DK2454266T3 (pl) |
| ES (1) | ES2429525T3 (pl) |
| HR (1) | HRP20130941T1 (pl) |
| MX (1) | MX2012000680A (pl) |
| PL (1) | PL2454266T3 (pl) |
| PT (1) | PT2454266E (pl) |
| RU (1) | RU2543721C2 (pl) |
| SI (1) | SI2454266T1 (pl) |
| SM (1) | SMT201300112B (pl) |
| TW (1) | TWI537276B (pl) |
| WO (1) | WO2011008172A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113559075A (zh) | 2014-11-17 | 2021-10-29 | 康泰科思特生物制药公司 | 奥那司酮延长释放组合物和方法 |
| CA2998924A1 (en) | 2015-09-25 | 2017-03-30 | Context Biopharma Inc. | Methods of making onapristone intermediates |
| JP2019503353A (ja) | 2015-12-15 | 2019-02-07 | コンテキスト・バイオファーマ・インコーポレイテッド | 非晶質オナプリストン組成物およびそれを作製する方法 |
| US20180148471A1 (en) | 2016-11-30 | 2018-05-31 | Arno Therapeutics, Inc. | Methods for onapristone synthesis dehydration and deprotection |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY110603A (en) * | 1993-05-27 | 1998-08-29 | Novartis Ag | Tetrahydropyran derivatives |
| WO2004078682A2 (en) * | 2003-03-05 | 2004-09-16 | Irm Llc | Cyclic compounds and compositions as protein kinase inhibitors |
| EP1951729B1 (en) * | 2005-11-16 | 2014-06-25 | Cell Therapeutics, Inc. | Oxygen linked pyrimidine derivatives |
-
2010
- 2010-07-14 MX MX2012000680A patent/MX2012000680A/es active IP Right Grant
- 2010-07-14 ES ES10737645T patent/ES2429525T3/es active Active
- 2010-07-14 JP JP2012520571A patent/JP6013911B2/ja active Active
- 2010-07-14 CA CA2768210A patent/CA2768210C/en active Active
- 2010-07-14 DK DK10737645.1T patent/DK2454266T3/da active
- 2010-07-14 SI SI201030347T patent/SI2454266T1/sl unknown
- 2010-07-14 PT PT107376451T patent/PT2454266E/pt unknown
- 2010-07-14 PL PL10737645T patent/PL2454266T3/pl unknown
- 2010-07-14 WO PCT/SG2010/000265 patent/WO2011008172A1/en not_active Ceased
- 2010-07-14 BR BR112012000750-5A patent/BR112012000750B1/pt active IP Right Grant
- 2010-07-14 RU RU2012105044/04A patent/RU2543721C2/ru active
- 2010-07-14 HR HRP20130941AT patent/HRP20130941T1/hr unknown
- 2010-07-14 US US13/384,139 patent/US9062074B2/en active Active
- 2010-07-14 EP EP10737645.1A patent/EP2454266B1/en active Active
- 2010-07-14 CN CN201080032627.5A patent/CN102762577B/zh active Active
- 2010-07-15 TW TW099123331A patent/TWI537276B/zh active
- 2010-07-15 AR ARP100102594A patent/AR077483A1/es not_active Application Discontinuation
-
2013
- 2013-10-04 SM SM201300112T patent/SMT201300112B/xx unknown
-
2015
- 2015-05-07 JP JP2015094972A patent/JP2015164941A/ja active Pending
-
2019
- 2019-08-05 AR ARP190102219A patent/AR114987A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US9062074B2 (en) | 2015-06-23 |
| HK1178159A1 (en) | 2013-09-06 |
| EP2454266B1 (en) | 2013-07-10 |
| CA2768210A1 (en) | 2011-01-20 |
| TWI537276B (zh) | 2016-06-11 |
| CN102762577A (zh) | 2012-10-31 |
| DK2454266T3 (da) | 2013-09-08 |
| TW201107336A (en) | 2011-03-01 |
| CN102762577B (zh) | 2015-01-07 |
| JP2012533539A (ja) | 2012-12-27 |
| JP6013911B2 (ja) | 2016-10-25 |
| BR112012000750A8 (pt) | 2018-02-06 |
| BR112012000750B1 (pt) | 2021-05-25 |
| JP2015164941A (ja) | 2015-09-17 |
| AR114987A2 (es) | 2020-11-11 |
| MX2012000680A (es) | 2012-02-28 |
| EP2454266A1 (en) | 2012-05-23 |
| RU2543721C2 (ru) | 2015-03-10 |
| HRP20130941T1 (hr) | 2013-11-08 |
| US20120196876A1 (en) | 2012-08-02 |
| PT2454266E (pt) | 2013-10-10 |
| RU2012105044A (ru) | 2013-08-20 |
| ES2429525T3 (es) | 2013-11-15 |
| WO2011008172A1 (en) | 2011-01-20 |
| AR077483A1 (es) | 2011-08-31 |
| BR112012000750A2 (pt) | 2016-08-09 |
| CA2768210C (en) | 2017-08-15 |
| SI2454266T1 (sl) | 2013-10-30 |
| SMT201300112B (it) | 2013-11-08 |
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