ES2524723T3 - Fructosil peptidil oxidasa y un sensor para analizar una proteína glucosilada - Google Patents
Fructosil peptidil oxidasa y un sensor para analizar una proteína glucosilada Download PDFInfo
- Publication number
- ES2524723T3 ES2524723T3 ES10751788.0T ES10751788T ES2524723T3 ES 2524723 T3 ES2524723 T3 ES 2524723T3 ES 10751788 T ES10751788 T ES 10751788T ES 2524723 T3 ES2524723 T3 ES 2524723T3
- Authority
- ES
- Spain
- Prior art keywords
- glycosylated protein
- nitrosoaniline
- analyze
- sensor
- fructosyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/004—Enzyme electrodes mediator-assisted
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/723—Glycosylated haemoglobin
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09009968A EP2281900A1 (en) | 2009-08-03 | 2009-08-03 | Fructosyl peptidyl oxidase and sensor for assaying a glycated protein |
| EP09009968 | 2009-08-03 | ||
| PCT/EP2010/004707 WO2011015325A1 (en) | 2009-08-03 | 2010-08-02 | Fructosyl peptidyl oxidase and sensor for assaying a glycated protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2524723T3 true ES2524723T3 (es) | 2014-12-11 |
Family
ID=41448516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES10751788.0T Active ES2524723T3 (es) | 2009-08-03 | 2010-08-02 | Fructosil peptidil oxidasa y un sensor para analizar una proteína glucosilada |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8721853B2 (https=) |
| EP (2) | EP2281900A1 (https=) |
| JP (1) | JP5870027B2 (https=) |
| CN (1) | CN102575278B (https=) |
| ES (1) | ES2524723T3 (https=) |
| WO (1) | WO2011015325A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102171338B (zh) * | 2008-10-10 | 2014-08-13 | 东洋纺织株式会社 | 具有果糖基缬氨酰基组氨酸氧化酶活性的蛋白质及其修饰产物以及其应用 |
| US9708586B2 (en) | 2010-08-06 | 2017-07-18 | Kikkoman Corporation | Amadoriase having altered substrate specificity |
| WO2012018094A1 (ja) * | 2010-08-06 | 2012-02-09 | キッコーマン株式会社 | 基質特異性が改変されたアマドリアーゼ |
| JP6282115B2 (ja) | 2011-12-28 | 2018-02-21 | キッコーマン株式会社 | 熱安定性が向上したアマドリアーゼ、その遺伝子および組換えdnaならびに熱安定性が向上したアマドリアーゼの製造法 |
| WO2013162035A1 (ja) | 2012-04-27 | 2013-10-31 | キッコーマン株式会社 | フルクトシルヘキサペプチドに作用する改変型アマドリアーゼ |
| JP2014102144A (ja) * | 2012-11-20 | 2014-06-05 | Nipro Corp | 糖化ヘモグロビン測定キットおよび糖化ヘモグロビン測定方法 |
| ES2848705T3 (es) | 2013-08-09 | 2021-08-11 | Kikkoman Corp | Amadoriasa modificada y método para producirla, agente para mejorar la resistencia a tensioactivos de la amadoriasa y composición para medir la HbA1c usando la misma |
| CN105683390B (zh) | 2013-10-25 | 2021-02-26 | 龟甲万株式会社 | 使用作用于糖基化肽的阿马多里酶的HbA1c测定方法 |
| JP6542671B2 (ja) * | 2013-10-25 | 2019-07-10 | キッコーマン株式会社 | ヘモグロビンA1cの測定方法および測定キット |
| EP3786291B1 (en) | 2014-10-24 | 2023-10-18 | Kikkoman Corporation | Amadoriase having enhanced dehydrogenase activity |
| WO2016072520A1 (ja) | 2014-11-07 | 2016-05-12 | キッコーマン株式会社 | アニオン性界面活性剤耐性が向上したアマドリアーゼ |
| EP3279323B1 (en) | 2015-04-03 | 2023-03-08 | Kikkoman Corporation | Amadoriase having improved specific activity |
| KR102596402B1 (ko) | 2016-04-22 | 2023-10-31 | 기꼬만 가부시키가이샤 | HbA1c 디히드로게나아제 |
| WO2018012607A1 (ja) | 2016-07-13 | 2018-01-18 | キッコーマン株式会社 | 反応促進剤 |
| TWI668229B (zh) | 2016-12-13 | 2019-08-11 | 財團法人工業技術研究院 | 重組蛋白質及其製造方法與應用 |
| JP7157063B2 (ja) | 2017-08-31 | 2022-10-19 | キッコーマン株式会社 | 糖化ヘモグロビンオキシダーゼ改変体及び測定方法 |
| EP3887398A4 (en) * | 2018-11-29 | 2022-10-19 | Polymer Technology Systems, Inc. | SYSTEMS AND METHODS FOR ELECTROCHEMICAL DETECTION OF HEMOGLOBIN AT THE POINT OF SUPPLY |
| CN113075143B (zh) * | 2021-03-31 | 2023-01-03 | 奥研生物科技(南京)有限公司 | 一种糖化血红蛋白检测试剂及其检测方法 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3826922A1 (de) | 1988-08-09 | 1990-02-22 | Boehringer Mannheim Gmbh | Verfahren zur kolorimetrischen bestimmung eines analyten mittels enzymatischer oxidation |
| DE4003194A1 (de) * | 1990-02-03 | 1991-08-08 | Boehringer Mannheim Gmbh | Verfahren und sensorelektrodensystem zur elektrochemischen bestimmung eines analyts oder einer oxidoreduktase sowie verwendung hierfuer geeigneter verbindungen |
| US5286362A (en) * | 1990-02-03 | 1994-02-15 | Boehringer Mannheim Gmbh | Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor |
| DE19521019A1 (de) | 1995-06-13 | 1996-12-19 | Boehringer Mannheim Gmbh | Verfahren und Mittel zur gleichzeitigen kolorimetrischen und elektrochemischen Messung eines Analyten |
| DE19629656A1 (de) | 1996-07-23 | 1998-01-29 | Boehringer Mannheim Gmbh | Diagnostischer Testträger mit mehrschichtigem Testfeld und Verfahren zur Bestimmung von Analyt mit dessen Hilfe |
| JP3842391B2 (ja) * | 1997-08-05 | 2006-11-08 | アークレイ株式会社 | フルクトシルアミノ酸オキシダーゼをコードするdna |
| DE19753847A1 (de) | 1997-12-04 | 1999-06-10 | Roche Diagnostics Gmbh | Analytisches Testelement mit Kapillarkanal |
| US5997817A (en) | 1997-12-05 | 1999-12-07 | Roche Diagnostics Corporation | Electrochemical biosensor test strip |
| CN1620512B (zh) * | 2000-07-14 | 2010-06-02 | 爱科来株式会社 | 糖基化血红蛋白的选择性测定方法 |
| JP4231668B2 (ja) * | 2001-09-04 | 2009-03-04 | キッコーマン株式会社 | 新規なフルクトシルペプチドオキシダーゼ |
| AU2003235973A1 (en) | 2002-06-07 | 2003-12-22 | Arkray, Inc. | Method of assay by oxidation-reduction reaction with formazan |
| DE10305050A1 (de) * | 2003-02-07 | 2004-08-19 | Roche Diagnostics Gmbh | Analytisches Testelement und Verfahren für Blutuntersuchungen |
| JP4227820B2 (ja) * | 2003-03-12 | 2009-02-18 | 旭化成ファーマ株式会社 | 新規な酵素 |
| WO2004104203A1 (ja) | 2003-05-21 | 2004-12-02 | Asahi Kasei Pharma Corporation | ヘモグロビンA1c測定法およびそれに用いる酵素とその製造法 |
| JP2007524816A (ja) | 2003-06-20 | 2007-08-30 | エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト | 細い均一な試薬ストリップの製造方法およびその試薬 |
| JP2005110657A (ja) | 2003-09-18 | 2005-04-28 | Kikkoman Corp | α−糖化ジペプチドの製造法及びα−糖化ジペプチドの測定法 |
| EP1726660A4 (en) * | 2004-03-17 | 2009-08-05 | Daiichi Pure Chemicals Co Ltd | METHOD OF MEASURING GLYCOPROTEIN |
| JP2005261383A (ja) * | 2004-03-22 | 2005-09-29 | Asahi Kasei Pharma Kk | キャリブレーション方法 |
| JP4373260B2 (ja) | 2004-03-29 | 2009-11-25 | 一則 片岡 | 高分子複合体 |
| DE102004023662A1 (de) * | 2004-05-06 | 2005-12-01 | Senslab-Gesellschaft Zur Entwicklung Und Herstellung Bioelektrochemischer Sensoren Mbh | Voltammetrischer Mikrofluidiksensor und Verfahren zum Nachweis von glykiertem Hämoglobin |
| JP4631028B2 (ja) * | 2005-04-04 | 2011-02-16 | 独立行政法人産業技術総合研究所 | バイオセンサー検出部 |
| US20070026523A1 (en) | 2005-07-27 | 2007-02-01 | Daiichi Pure Chemicals Co., Ltd. | Method for stabilizing leuco dye |
| WO2007072941A1 (ja) * | 2005-12-22 | 2007-06-28 | Kyowa Medex Co., Ltd. | 糖化タンパク質の測定方法 |
| JPWO2007094354A1 (ja) * | 2006-02-14 | 2009-07-09 | 独立行政法人産業技術総合研究所 | ヘモグロビンA1cセンサ |
| JP5074386B2 (ja) * | 2006-04-25 | 2012-11-14 | キッコーマン株式会社 | 熱安定性に優れた真核型アマドリアーゼ、その遺伝子及び組換え体dna、並びに熱安定性に優れた真核型アマドリアーゼの製造法 |
| DE102006021401A1 (de) * | 2006-05-08 | 2007-12-13 | Henkel Kgaa | Amadoriasen in Wasch- und Reinigungsmitteln |
| JP4854651B2 (ja) * | 2007-12-19 | 2012-01-18 | 積水化学工業株式会社 | ヘモグロビン類の測定装置及びヘモグロビン類の測定方法 |
| EP2105735B1 (en) | 2006-12-26 | 2014-11-26 | Sekisui Chemical Co., Ltd. | STABLE HEMOGLOBIN A1c MEASUREMENT METHOD AND ELECTROPHORESIS APPARATUS |
| JP2008268197A (ja) * | 2007-03-29 | 2008-11-06 | Cci Corp | タンパク質固定化膜、タンパク質の固定化方法およびバイオセンサ |
| CN101622532B (zh) | 2007-04-27 | 2013-08-14 | 爱科来株式会社 | 分析芯片以及分析装置 |
| JP5181576B2 (ja) * | 2007-08-17 | 2013-04-10 | ソニー株式会社 | 燃料電池の製造方法、燃料電池および電子機器 |
| CN102171338B (zh) * | 2008-10-10 | 2014-08-13 | 东洋纺织株式会社 | 具有果糖基缬氨酰基组氨酸氧化酶活性的蛋白质及其修饰产物以及其应用 |
| JP5476021B2 (ja) * | 2008-10-17 | 2014-04-23 | 東洋紡株式会社 | フルクトシルアミノ酸オキシダーゼ改変体およびその利用 |
| JP5465415B2 (ja) | 2008-10-29 | 2014-04-09 | 東洋紡株式会社 | フルクトシルアミノ酸測定用酵素、およびその利用法 |
-
2009
- 2009-08-03 EP EP09009968A patent/EP2281900A1/en not_active Withdrawn
-
2010
- 2010-08-02 ES ES10751788.0T patent/ES2524723T3/es active Active
- 2010-08-02 WO PCT/EP2010/004707 patent/WO2011015325A1/en not_active Ceased
- 2010-08-02 JP JP2012523235A patent/JP5870027B2/ja active Active
- 2010-08-02 CN CN201080033796.0A patent/CN102575278B/zh active Active
- 2010-08-02 EP EP10751788.0A patent/EP2462239B1/en active Active
-
2012
- 2012-02-03 US US13/365,384 patent/US8721853B2/en active Active
-
2014
- 2014-03-27 US US14/227,693 patent/US8962271B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20120202235A1 (en) | 2012-08-09 |
| CN102575278A (zh) | 2012-07-11 |
| CN102575278B (zh) | 2014-02-19 |
| JP5870027B2 (ja) | 2016-02-24 |
| US8721853B2 (en) | 2014-05-13 |
| US8962271B2 (en) | 2015-02-24 |
| EP2281900A1 (en) | 2011-02-09 |
| HK1172930A1 (en) | 2013-05-03 |
| WO2011015325A1 (en) | 2011-02-10 |
| EP2462239A1 (en) | 2012-06-13 |
| US20140227728A1 (en) | 2014-08-14 |
| JP2013500728A (ja) | 2013-01-10 |
| EP2462239B1 (en) | 2014-09-17 |
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