ES2524723T3 - Fructosil peptidil oxidasa y un sensor para analizar una proteína glucosilada - Google Patents

Fructosil peptidil oxidasa y un sensor para analizar una proteína glucosilada Download PDF

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Publication number
ES2524723T3
ES2524723T3 ES10751788.0T ES10751788T ES2524723T3 ES 2524723 T3 ES2524723 T3 ES 2524723T3 ES 10751788 T ES10751788 T ES 10751788T ES 2524723 T3 ES2524723 T3 ES 2524723T3
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Spain
Prior art keywords
glycosylated protein
nitrosoaniline
analyze
sensor
fructosyl
Prior art date
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Active
Application number
ES10751788.0T
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English (en)
Spanish (es)
Inventor
Koji Sode
Kazunori Ikebukuro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Ultizyme International Ltd
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F Hoffmann La Roche AG
Ultizyme International Ltd
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/004Enzyme electrodes mediator-assisted
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • G01N33/723Glycosylated haemoglobin

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
ES10751788.0T 2009-08-03 2010-08-02 Fructosil peptidil oxidasa y un sensor para analizar una proteína glucosilada Active ES2524723T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09009968A EP2281900A1 (en) 2009-08-03 2009-08-03 Fructosyl peptidyl oxidase and sensor for assaying a glycated protein
EP09009968 2009-08-03
PCT/EP2010/004707 WO2011015325A1 (en) 2009-08-03 2010-08-02 Fructosyl peptidyl oxidase and sensor for assaying a glycated protein

Publications (1)

Publication Number Publication Date
ES2524723T3 true ES2524723T3 (es) 2014-12-11

Family

ID=41448516

Family Applications (1)

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ES10751788.0T Active ES2524723T3 (es) 2009-08-03 2010-08-02 Fructosil peptidil oxidasa y un sensor para analizar una proteína glucosilada

Country Status (6)

Country Link
US (2) US8721853B2 (https=)
EP (2) EP2281900A1 (https=)
JP (1) JP5870027B2 (https=)
CN (1) CN102575278B (https=)
ES (1) ES2524723T3 (https=)
WO (1) WO2011015325A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102171338B (zh) 2008-10-10 2014-08-13 东洋纺织株式会社 具有果糖基缬氨酰基组氨酸氧化酶活性的蛋白质及其修饰产物以及其应用
WO2012018094A1 (ja) * 2010-08-06 2012-02-09 キッコーマン株式会社 基質特異性が改変されたアマドリアーゼ
US9708586B2 (en) 2010-08-06 2017-07-18 Kikkoman Corporation Amadoriase having altered substrate specificity
EP2808386B1 (en) 2011-12-28 2018-11-28 Kikkoman Corporation Amadoriase having improved thermal stability, gene and recombinant dna of same, and method for producing amadoriase having improved thermal stability
WO2013162035A1 (ja) 2012-04-27 2013-10-31 キッコーマン株式会社 フルクトシルヘキサペプチドに作用する改変型アマドリアーゼ
JP2014102144A (ja) * 2012-11-20 2014-06-05 Nipro Corp 糖化ヘモグロビン測定キットおよび糖化ヘモグロビン測定方法
US10619183B2 (en) 2013-08-09 2020-04-14 Kikkoman Corporation Modified amadoriase and method for producing the same, agent for improving surfactant resistance of amadoriase and composition for measuring HbA1c using the same
EP3061829B1 (en) * 2013-10-25 2021-09-22 Kikkoman Corporation METHOD FOR MEASUREMENT OF HbA1c USING AMADORIASE THAT REACTS WITH GLYCATED PEPTIDE
JP6542671B2 (ja) * 2013-10-25 2019-07-10 キッコーマン株式会社 ヘモグロビンA1cの測定方法および測定キット
CN107148475A (zh) 2014-10-24 2017-09-08 龟甲万株式会社 脱氢酶活性提高的阿马多里酶
US11198852B2 (en) 2014-11-07 2021-12-14 Kikkoman Corporation Amadoriase having enhanced anionic surfactant tolerance
US10934530B2 (en) 2015-04-03 2021-03-02 Kikkoman Corporation Amadoriase having improved specific activity
JP7471772B2 (ja) 2016-04-22 2024-04-22 キッコーマン株式会社 HbA1cデヒドロゲナーゼ
WO2018012607A1 (ja) 2016-07-13 2018-01-18 キッコーマン株式会社 反応促進剤
US10533160B2 (en) 2016-12-13 2020-01-14 Industrial Technology Research Institute Recombinant protein, and preparation method and application thereof
WO2019045052A1 (ja) 2017-08-31 2019-03-07 キッコーマン株式会社 糖化ヘモグロビンオキシダーゼ改変体及び測定方法
US11693016B2 (en) * 2018-11-29 2023-07-04 Polymer Technology Systems, Inc. Systems and methods for electrochemical point-of-care detection of hemoglobin
CN113075143B (zh) * 2021-03-31 2023-01-03 奥研生物科技(南京)有限公司 一种糖化血红蛋白检测试剂及其检测方法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3826922A1 (de) 1988-08-09 1990-02-22 Boehringer Mannheim Gmbh Verfahren zur kolorimetrischen bestimmung eines analyten mittels enzymatischer oxidation
DE4003194A1 (de) * 1990-02-03 1991-08-08 Boehringer Mannheim Gmbh Verfahren und sensorelektrodensystem zur elektrochemischen bestimmung eines analyts oder einer oxidoreduktase sowie verwendung hierfuer geeigneter verbindungen
US5286362A (en) * 1990-02-03 1994-02-15 Boehringer Mannheim Gmbh Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor
DE19521019A1 (de) 1995-06-13 1996-12-19 Boehringer Mannheim Gmbh Verfahren und Mittel zur gleichzeitigen kolorimetrischen und elektrochemischen Messung eines Analyten
DE19629656A1 (de) 1996-07-23 1998-01-29 Boehringer Mannheim Gmbh Diagnostischer Testträger mit mehrschichtigem Testfeld und Verfahren zur Bestimmung von Analyt mit dessen Hilfe
JP3842391B2 (ja) * 1997-08-05 2006-11-08 アークレイ株式会社 フルクトシルアミノ酸オキシダーゼをコードするdna
DE19753847A1 (de) 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Analytisches Testelement mit Kapillarkanal
US5997817A (en) 1997-12-05 1999-12-07 Roche Diagnostics Corporation Electrochemical biosensor test strip
JP3971702B2 (ja) 2000-07-14 2007-09-05 アークレイ株式会社 糖化ヘモグロビンの選択的測定方法
JP4231668B2 (ja) * 2001-09-04 2009-03-04 キッコーマン株式会社 新規なフルクトシルペプチドオキシダーゼ
AU2003235973A1 (en) 2002-06-07 2003-12-22 Arkray, Inc. Method of assay by oxidation-reduction reaction with formazan
DE10305050A1 (de) * 2003-02-07 2004-08-19 Roche Diagnostics Gmbh Analytisches Testelement und Verfahren für Blutuntersuchungen
JP4227820B2 (ja) * 2003-03-12 2009-02-18 旭化成ファーマ株式会社 新規な酵素
DE602004030328D1 (de) * 2003-05-21 2011-01-13 Asahi Kasei Pharma Corp Verfahren zur messung von glykoliertem hämoglobin a1c, dafür zu verwendendes enzym und verfahren zur herstellung davon
TR201810169T4 (tr) * 2003-06-20 2018-08-27 Hoffmann La Roche Dar, homojen belirteç şeritlerinin üretilmesi için yöntem ve belirteç.
JP2005110657A (ja) 2003-09-18 2005-04-28 Kikkoman Corp α−糖化ジペプチドの製造法及びα−糖化ジペプチドの測定法
CN1957090A (zh) * 2004-03-17 2007-05-02 第一化学药品株式会社 糖蛋白的测定方法
JP2005261383A (ja) * 2004-03-22 2005-09-29 Asahi Kasei Pharma Kk キャリブレーション方法
JP4373260B2 (ja) 2004-03-29 2009-11-25 一則 片岡 高分子複合体
DE102004023662A1 (de) * 2004-05-06 2005-12-01 Senslab-Gesellschaft Zur Entwicklung Und Herstellung Bioelektrochemischer Sensoren Mbh Voltammetrischer Mikrofluidiksensor und Verfahren zum Nachweis von glykiertem Hämoglobin
JP4631028B2 (ja) * 2005-04-04 2011-02-16 独立行政法人産業技術総合研究所 バイオセンサー検出部
JP4889396B2 (ja) * 2005-07-27 2012-03-07 積水メディカル株式会社 ロイコ色素の安定化方法
WO2007072941A1 (ja) * 2005-12-22 2007-06-28 Kyowa Medex Co., Ltd. 糖化タンパク質の測定方法
WO2007094354A1 (ja) * 2006-02-14 2007-08-23 National Institute Of Advanced Industrial Science And Technology ヘモグロビンA1cセンサ
JP5074386B2 (ja) * 2006-04-25 2012-11-14 キッコーマン株式会社 熱安定性に優れた真核型アマドリアーゼ、その遺伝子及び組換え体dna、並びに熱安定性に優れた真核型アマドリアーゼの製造法
DE102006021401A1 (de) * 2006-05-08 2007-12-13 Henkel Kgaa Amadoriasen in Wasch- und Reinigungsmitteln
US9017536B2 (en) 2006-12-26 2015-04-28 Sekisui Chemical Co., Ltd. Hemoglobin measurement method and electrophoresis apparatus
JP4854651B2 (ja) * 2007-12-19 2012-01-18 積水化学工業株式会社 ヘモグロビン類の測定装置及びヘモグロビン類の測定方法
JP2008268197A (ja) * 2007-03-29 2008-11-06 Cci Corp タンパク質固定化膜、タンパク質の固定化方法およびバイオセンサ
CN101622532B (zh) 2007-04-27 2013-08-14 爱科来株式会社 分析芯片以及分析装置
JP5181576B2 (ja) * 2007-08-17 2013-04-10 ソニー株式会社 燃料電池の製造方法、燃料電池および電子機器
CN102171338B (zh) * 2008-10-10 2014-08-13 东洋纺织株式会社 具有果糖基缬氨酰基组氨酸氧化酶活性的蛋白质及其修饰产物以及其应用
JP5476021B2 (ja) * 2008-10-17 2014-04-23 東洋紡株式会社 フルクトシルアミノ酸オキシダーゼ改変体およびその利用
JP5465415B2 (ja) 2008-10-29 2014-04-09 東洋紡株式会社 フルクトシルアミノ酸測定用酵素、およびその利用法

Also Published As

Publication number Publication date
JP2013500728A (ja) 2013-01-10
CN102575278B (zh) 2014-02-19
US20120202235A1 (en) 2012-08-09
JP5870027B2 (ja) 2016-02-24
US8962271B2 (en) 2015-02-24
HK1172930A1 (en) 2013-05-03
WO2011015325A1 (en) 2011-02-10
US8721853B2 (en) 2014-05-13
EP2462239B1 (en) 2014-09-17
EP2462239A1 (en) 2012-06-13
EP2281900A1 (en) 2011-02-09
CN102575278A (zh) 2012-07-11
US20140227728A1 (en) 2014-08-14

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