ES2436020T3 - Derivados de sulfonamida sustituidos - Google Patents
Derivados de sulfonamida sustituidos Download PDFInfo
- Publication number
- ES2436020T3 ES2436020T3 ES07818500T ES07818500T ES2436020T3 ES 2436020 T3 ES2436020 T3 ES 2436020T3 ES 07818500 T ES07818500 T ES 07818500T ES 07818500 T ES07818500 T ES 07818500T ES 2436020 T3 ES2436020 T3 ES 2436020T3
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- substituted
- group
- aryl
- sulfonamide derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 229940124530 sulfonamide Drugs 0.000 title abstract 2
- 150000003456 sulfonamides Chemical class 0.000 title abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 8
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000005842 heteroatom Chemical group 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Child & Adolescent Psychology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Hydrogenated Pyridines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102006046743 | 2006-09-29 | ||
| DE102006046743 | 2006-09-29 | ||
| PCT/EP2007/008417 WO2008040492A1 (de) | 2006-09-29 | 2007-09-27 | Substituierte sulfonamid-derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2436020T3 true ES2436020T3 (es) | 2013-12-26 |
Family
ID=38740241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07818500T Active ES2436020T3 (es) | 2006-09-29 | 2007-09-27 | Derivados de sulfonamida sustituidos |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US20080153843A1 (enExample) |
| EP (2) | EP2383267A1 (enExample) |
| JP (1) | JP5405303B2 (enExample) |
| KR (1) | KR20090079914A (enExample) |
| CN (1) | CN101553481A (enExample) |
| AU (1) | AU2007304475B2 (enExample) |
| BR (1) | BRPI0714764A2 (enExample) |
| CA (1) | CA2664810A1 (enExample) |
| CO (1) | CO6170358A2 (enExample) |
| CY (1) | CY1114669T1 (enExample) |
| DK (1) | DK2066659T3 (enExample) |
| ES (1) | ES2436020T3 (enExample) |
| HR (1) | HRP20130958T1 (enExample) |
| IL (1) | IL197814A0 (enExample) |
| MX (1) | MX2009003382A (enExample) |
| NO (1) | NO20091299L (enExample) |
| NZ (1) | NZ575566A (enExample) |
| PL (1) | PL2066659T3 (enExample) |
| PT (1) | PT2066659E (enExample) |
| RU (1) | RU2462464C2 (enExample) |
| SI (1) | SI2066659T1 (enExample) |
| WO (1) | WO2008040492A1 (enExample) |
| ZA (1) | ZA200902915B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102007020493A1 (de) * | 2007-04-30 | 2008-11-06 | Grünenthal GmbH | Substituierte Amid-Derivate |
| CA2712266A1 (en) | 2008-01-17 | 2009-07-23 | Gruenenthal Gmbh | Substituted sulfonamide derivatives |
| US8318769B2 (en) * | 2008-04-08 | 2012-11-27 | Gruenethal Gmbh | Substituted sulfonamide compounds |
| TW201022267A (en) | 2008-10-23 | 2010-06-16 | Gruenenthal Gmbh | Substituierte pyrimidin-und triazin-derivate |
| JP2012506883A (ja) | 2008-10-29 | 2012-03-22 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 置換されたスピロアミン |
| TW201020247A (en) | 2008-11-06 | 2010-06-01 | Gruenenthal Gmbh | Substituierte disulfonamide |
| TW201031665A (en) | 2009-02-04 | 2010-09-01 | Gruenenthal Gmbh | Substituted indole-compound |
| TW201030007A (en) | 2009-02-06 | 2010-08-16 | Gruenenthal Gmbh | Substituted spiro-amides as b1r modulators |
| TW201035102A (en) * | 2009-03-04 | 2010-10-01 | Gruenethal Gmbh | Sulfonylated tetrahydroazolopyrazines and their use as medicinal products |
| TW201038572A (en) | 2009-03-25 | 2010-11-01 | Gruenenthal Gmbh | Substituted spiro-amide compounds |
| CA2764622A1 (en) | 2009-06-08 | 2010-12-16 | Stefan Schunk | Substituted benzimidazoles, benzothiazoles and benzoxazoles |
| IN2012CN09242A (enExample) | 2010-04-05 | 2015-08-21 | Shionogi & Co | |
| MX2013002446A (es) | 2010-09-03 | 2013-04-08 | Gruenenthal Gmbh | Derivados de tetrahidropirrolopirazina sustituidos. |
| TW201217312A (en) | 2010-09-22 | 2012-05-01 | Gruenenthal Gmbh | Substituted benzamide compounds |
| CN106748627A (zh) * | 2016-11-14 | 2017-05-31 | 苏州市罗森助剂有限公司 | 一种一锅法制备3,5‑二甲基溴苯的方法 |
| CA2965062A1 (en) * | 2017-04-25 | 2018-10-25 | Nova Chemicals Corporation | Complex comprising odh unit with integrated oxygen separation module |
| KR101798840B1 (ko) | 2017-05-17 | 2017-11-17 | 주식회사 레고켐 바이오사이언스 | 신규 오토탁신 저해 화합물 및 이를 함유하는 약제학적 조성물 |
| CN109810031B (zh) * | 2017-11-21 | 2023-10-17 | 乳源瑶族自治县东阳光生物科技有限公司 | 非罗考昔中间体的制备方法 |
| WO2023028056A1 (en) | 2021-08-24 | 2023-03-02 | Genentech, Inc. | 3-amino piperidyl sodium channel inhibitors |
| CN116253667B (zh) * | 2022-12-27 | 2024-08-30 | 煤炭科学研究总院有限公司 | 一种聚集诱导发光材料及其制备方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0835659T3 (da) * | 1996-10-14 | 2005-04-18 | Aventis Pharma Gmbh | Anvendelse af ikke-peptidiske antagonister for bradykinin til fremstilling af lægemidler til behandling og forebyggelse af Alzheimer's sygdom |
| FR2790260B1 (fr) * | 1999-02-26 | 2001-05-04 | Fournier Ind & Sante | Nouveaux composes de n-(benzenesulfonamide), procede de preparation et utilisation en therapeutique |
| US6589978B2 (en) * | 2000-06-30 | 2003-07-08 | Hoffman-La Roche Inc. | 1-sulfonyl pyrrolidine derivatives |
| US20040171614A1 (en) * | 2002-02-06 | 2004-09-02 | Schering-Plough Corporation | Novel gamma secretase inhibitors |
| TW200302717A (en) * | 2002-02-06 | 2003-08-16 | Schering Corp | Novel gamma secretase inhibitors |
| US7256186B2 (en) * | 2002-02-06 | 2007-08-14 | Schering Corporation | Gamma secretase inhibitors |
| JP2006522835A (ja) * | 2003-04-10 | 2006-10-05 | アムジェン インコーポレイテッド | 環状アミン誘導体およびブラジキニンによって媒介される炎症関連障害の処置におけるそれらの使用 |
| WO2005068448A1 (en) * | 2003-08-29 | 2005-07-28 | Ionix Pharmaceuticals Limited | Sulfonamides antagonising n-type calcium channels |
| CN1674594A (zh) * | 2004-03-23 | 2005-09-28 | 松下电器产业株式会社 | 器械控制装置、电器械、器械设置地点的设定系统、设定方法及程序 |
| CA2567343A1 (en) * | 2004-05-20 | 2005-12-01 | Elan Pharmaceuticals, Inc. | N-cyclic sulfonamido inhibitors of gamma secretase |
| EP1769092A4 (en) | 2004-06-29 | 2008-08-06 | Europ Nickel Plc | IMPROVED LIXIVIATION OF BASE METALS |
| DE102005013967A1 (de) * | 2004-11-05 | 2006-10-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Bradykinin-B1-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
| US20060217362A1 (en) * | 2004-12-29 | 2006-09-28 | Tung Jay S | Novel compounds useful for bradykinin B1 receptor antagonism |
| MX2007016203A (es) | 2005-06-29 | 2008-03-10 | Compumedics Ltd | Ensamble de sensor con puente conductivo. |
| WO2007101007A2 (en) * | 2006-02-23 | 2007-09-07 | Neurogen Corporation | Aryl sulfonyl heterocycles |
| TW200801513A (en) * | 2006-06-29 | 2008-01-01 | Fermiscan Australia Pty Ltd | Improved process |
| WO2008024692A1 (en) * | 2006-08-23 | 2008-02-28 | Neurogen Corporation | N-oxide aryl sulfones and sulfoxides |
| DE102007020493A1 (de) * | 2007-04-30 | 2008-11-06 | Grünenthal GmbH | Substituierte Amid-Derivate |
| CA2712266A1 (en) * | 2008-01-17 | 2009-07-23 | Gruenenthal Gmbh | Substituted sulfonamide derivatives |
| TW200940528A (en) * | 2008-03-05 | 2009-10-01 | Gruenenthal Gmbh | Substituted sulfonamide derivatives |
| CA2720735A1 (en) * | 2008-04-08 | 2009-10-15 | Gruenenthal Gmbh | Substituted sulfonamide derivatives |
| US8318769B2 (en) * | 2008-04-08 | 2012-11-27 | Gruenethal Gmbh | Substituted sulfonamide compounds |
| TW200944530A (en) * | 2008-04-09 | 2009-11-01 | Gruenenthal Chemie | Substituted sulfonamide derivatives |
-
2007
- 2007-09-27 PT PT78185006T patent/PT2066659E/pt unknown
- 2007-09-27 SI SI200731301T patent/SI2066659T1/sl unknown
- 2007-09-27 JP JP2009529606A patent/JP5405303B2/ja not_active Expired - Fee Related
- 2007-09-27 EP EP11006169A patent/EP2383267A1/de not_active Withdrawn
- 2007-09-27 KR KR1020097008960A patent/KR20090079914A/ko not_active Ceased
- 2007-09-27 NZ NZ575566A patent/NZ575566A/en not_active IP Right Cessation
- 2007-09-27 WO PCT/EP2007/008417 patent/WO2008040492A1/de not_active Ceased
- 2007-09-27 MX MX2009003382A patent/MX2009003382A/es active IP Right Grant
- 2007-09-27 AU AU2007304475A patent/AU2007304475B2/en not_active Ceased
- 2007-09-27 EP EP07818500.6A patent/EP2066659B1/de active Active
- 2007-09-27 ES ES07818500T patent/ES2436020T3/es active Active
- 2007-09-27 CN CNA2007800436108A patent/CN101553481A/zh active Pending
- 2007-09-27 HR HRP20130958TT patent/HRP20130958T1/hr unknown
- 2007-09-27 CA CA002664810A patent/CA2664810A1/en not_active Abandoned
- 2007-09-27 PL PL07818500T patent/PL2066659T3/pl unknown
- 2007-09-27 DK DK07818500.6T patent/DK2066659T3/da active
- 2007-09-27 RU RU2009115960/04A patent/RU2462464C2/ru not_active IP Right Cessation
- 2007-09-27 BR BRPI0714764-3A2A patent/BRPI0714764A2/pt not_active IP Right Cessation
- 2007-09-28 US US11/905,381 patent/US20080153843A1/en not_active Abandoned
-
2009
- 2009-03-26 IL IL197814A patent/IL197814A0/en unknown
- 2009-03-30 CO CO09032332A patent/CO6170358A2/es active IP Right Grant
- 2009-03-30 NO NO20091299A patent/NO20091299L/no not_active Application Discontinuation
- 2009-04-28 ZA ZA2009/02915A patent/ZA200902915B/en unknown
-
2010
- 2010-08-24 US US12/862,297 patent/US8435978B2/en not_active Expired - Fee Related
- 2010-08-24 US US12/862,271 patent/US20100324009A1/en not_active Abandoned
-
2013
- 2013-11-21 CY CY20131101046T patent/CY1114669T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101553481A (zh) | 2009-10-07 |
| US20100317644A1 (en) | 2010-12-16 |
| NO20091299L (no) | 2009-04-29 |
| EP2066659B1 (de) | 2013-08-28 |
| ZA200902915B (en) | 2010-02-24 |
| BRPI0714764A2 (pt) | 2014-12-30 |
| JP2010504930A (ja) | 2010-02-18 |
| PL2066659T3 (pl) | 2014-01-31 |
| DK2066659T3 (da) | 2013-12-09 |
| NZ575566A (en) | 2011-05-27 |
| JP5405303B2 (ja) | 2014-02-05 |
| IL197814A0 (en) | 2009-12-24 |
| EP2066659A1 (de) | 2009-06-10 |
| WO2008040492A1 (de) | 2008-04-10 |
| HRP20130958T1 (hr) | 2013-11-22 |
| PT2066659E (pt) | 2013-11-07 |
| CY1114669T1 (el) | 2016-10-05 |
| AU2007304475A1 (en) | 2008-04-10 |
| US20100324009A1 (en) | 2010-12-23 |
| RU2009115960A (ru) | 2010-11-10 |
| CO6170358A2 (es) | 2010-06-18 |
| SI2066659T1 (sl) | 2013-10-30 |
| CA2664810A1 (en) | 2008-04-10 |
| US20080153843A1 (en) | 2008-06-26 |
| HK1132266A1 (en) | 2010-02-19 |
| AU2007304475B2 (en) | 2012-07-26 |
| MX2009003382A (es) | 2009-04-08 |
| US8435978B2 (en) | 2013-05-07 |
| EP2383267A1 (de) | 2011-11-02 |
| RU2462464C2 (ru) | 2012-09-27 |
| KR20090079914A (ko) | 2009-07-22 |
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