RU2462464C2 - Замещенные сульфамидные производные - Google Patents

Замещенные сульфамидные производные Download PDF

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Publication number
RU2462464C2
RU2462464C2 RU2009115960/04A RU2009115960A RU2462464C2 RU 2462464 C2 RU2462464 C2 RU 2462464C2 RU 2009115960/04 A RU2009115960/04 A RU 2009115960/04A RU 2009115960 A RU2009115960 A RU 2009115960A RU 2462464 C2 RU2462464 C2 RU 2462464C2
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RU
Russia
Prior art keywords
methoxy
piperidin
ethanone
dimethylphenylsulfonyl
piperazin
Prior art date
Application number
RU2009115960/04A
Other languages
English (en)
Russian (ru)
Other versions
RU2009115960A (ru
Inventor
Штефан ОБЕРБЁРШ (DE)
Штефан ОБЕРБЁРШ
Штефан ШУНК (DE)
Штефан ШУНК
Мелани РАЙХ (DE)
Мелани РАЙХ
Забине ХЕЕС (DE)
Забине ХЕЕС
Рут ЙОШТОК (DE)
Рут ЙОШТОК
Михаэль ЭНГЕЛЬС (BE)
Михаэль ЭНГЕЛЬС
Ахим КЛЕСС (DE)
Ахим КЛЕСС
Томас КРИСТОФ (DE)
Томас КРИСТОФ
Клаус ШИНЕ (DE)
Клаус ШИНЕ
Тино ГЕРМАНН (DE)
Тино ГЕРМАНН
Эдвард БЕЙСТЕРВЕЛД (NL)
Эдвард БЕЙСТЕРВЕЛД
Original Assignee
Грюненталь Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of RU2009115960A publication Critical patent/RU2009115960A/ru
Application granted granted Critical
Publication of RU2462464C2 publication Critical patent/RU2462464C2/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Indole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
RU2009115960/04A 2006-09-29 2007-09-27 Замещенные сульфамидные производные RU2462464C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102006046743.4 2006-09-29
DE102006046743 2006-09-29

Publications (2)

Publication Number Publication Date
RU2009115960A RU2009115960A (ru) 2010-11-10
RU2462464C2 true RU2462464C2 (ru) 2012-09-27

Family

ID=38740241

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2009115960/04A RU2462464C2 (ru) 2006-09-29 2007-09-27 Замещенные сульфамидные производные

Country Status (23)

Country Link
US (3) US20080153843A1 (enExample)
EP (2) EP2383267A1 (enExample)
JP (1) JP5405303B2 (enExample)
KR (1) KR20090079914A (enExample)
CN (1) CN101553481A (enExample)
AU (1) AU2007304475B2 (enExample)
BR (1) BRPI0714764A2 (enExample)
CA (1) CA2664810A1 (enExample)
CO (1) CO6170358A2 (enExample)
CY (1) CY1114669T1 (enExample)
DK (1) DK2066659T3 (enExample)
ES (1) ES2436020T3 (enExample)
HR (1) HRP20130958T1 (enExample)
IL (1) IL197814A0 (enExample)
MX (1) MX2009003382A (enExample)
NO (1) NO20091299L (enExample)
NZ (1) NZ575566A (enExample)
PL (1) PL2066659T3 (enExample)
PT (1) PT2066659E (enExample)
RU (1) RU2462464C2 (enExample)
SI (1) SI2066659T1 (enExample)
WO (1) WO2008040492A1 (enExample)
ZA (1) ZA200902915B (enExample)

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DE102007020493A1 (de) * 2007-04-30 2008-11-06 Grünenthal GmbH Substituierte Amid-Derivate
JP2011509962A (ja) * 2008-01-17 2011-03-31 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 置換スルホンアミド誘導体
RU2503674C2 (ru) * 2008-04-08 2014-01-10 Грюненталь Гмбх Замещенные производные сульфонамида
TW201022267A (en) 2008-10-23 2010-06-16 Gruenenthal Gmbh Substituierte pyrimidin-und triazin-derivate
AU2009309988A1 (en) 2008-10-29 2010-05-06 Grunenthal Gmbh Substituted spiroamines
TW201020247A (en) 2008-11-06 2010-06-01 Gruenenthal Gmbh Substituierte disulfonamide
TW201031665A (en) 2009-02-04 2010-09-01 Gruenenthal Gmbh Substituted indole-compound
TW201030007A (en) 2009-02-06 2010-08-16 Gruenenthal Gmbh Substituted spiro-amides as b1r modulators
TW201035102A (en) 2009-03-04 2010-10-01 Gruenethal Gmbh Sulfonylated tetrahydroazolopyrazines and their use as medicinal products
TW201038572A (en) 2009-03-25 2010-11-01 Gruenenthal Gmbh Substituted spiro-amide compounds
EP2440542B1 (en) 2009-06-08 2013-12-18 Grünenthal GmbH Substituted benzimidazoles, benzonthiazoles and benzoxazoles
AU2011236933A1 (en) 2010-04-05 2013-05-02 Shionogi & Co., Ltd. Cephem compound having catechol group
WO2012028331A1 (en) 2010-09-03 2012-03-08 Grünenthal GmbH Substituted tetrahydropyrrolopyrazine derivatives
TW201217312A (en) 2010-09-22 2012-05-01 Gruenenthal Gmbh Substituted benzamide compounds
CN106748627A (zh) * 2016-11-14 2017-05-31 苏州市罗森助剂有限公司 一种一锅法制备3,5‑二甲基溴苯的方法
CA2965062A1 (en) * 2017-04-25 2018-10-25 Nova Chemicals Corporation Complex comprising odh unit with integrated oxygen separation module
KR101798840B1 (ko) 2017-05-17 2017-11-17 주식회사 레고켐 바이오사이언스 신규 오토탁신 저해 화합물 및 이를 함유하는 약제학적 조성물
CN109810031B (zh) * 2017-11-21 2023-10-17 乳源瑶族自治县东阳光生物科技有限公司 非罗考昔中间体的制备方法
WO2023028056A1 (en) 2021-08-24 2023-03-02 Genentech, Inc. 3-amino piperidyl sodium channel inhibitors
CN116253667B (zh) * 2022-12-27 2024-08-30 煤炭科学研究总院有限公司 一种聚集诱导发光材料及其制备方法

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RU2272026C2 (ru) * 2000-06-30 2006-03-20 Ф.Хоффманн-Ля Рош Аг Производные сульфонилпирролидина
WO2006071775A2 (en) * 2004-12-29 2006-07-06 Elan Pharmaceuticals, Inc. Novel compounds useful for bradykinin b1 receptor antagonism

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DE59712118D1 (de) * 1996-10-14 2005-01-20 Aventis Pharma Gmbh Verwendung von nicht-peptidischen Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung und Prävention der Alzheimerischen Krankheit
FR2790260B1 (fr) * 1999-02-26 2001-05-04 Fournier Ind & Sante Nouveaux composes de n-(benzenesulfonamide), procede de preparation et utilisation en therapeutique
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RU2503674C2 (ru) * 2008-04-08 2014-01-10 Грюненталь Гмбх Замещенные производные сульфонамида
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Publication number Priority date Publication date Assignee Title
RU2272026C2 (ru) * 2000-06-30 2006-03-20 Ф.Хоффманн-Ля Рош Аг Производные сульфонилпирролидина
WO2006071775A2 (en) * 2004-12-29 2006-07-06 Elan Pharmaceuticals, Inc. Novel compounds useful for bradykinin b1 receptor antagonism

Also Published As

Publication number Publication date
RU2009115960A (ru) 2010-11-10
HK1132266A1 (en) 2010-02-19
AU2007304475A1 (en) 2008-04-10
US8435978B2 (en) 2013-05-07
CN101553481A (zh) 2009-10-07
EP2066659B1 (de) 2013-08-28
US20100317644A1 (en) 2010-12-16
HRP20130958T1 (hr) 2013-11-22
CA2664810A1 (en) 2008-04-10
MX2009003382A (es) 2009-04-08
SI2066659T1 (sl) 2013-10-30
ES2436020T3 (es) 2013-12-26
PL2066659T3 (pl) 2014-01-31
WO2008040492A1 (de) 2008-04-10
EP2383267A1 (de) 2011-11-02
EP2066659A1 (de) 2009-06-10
NO20091299L (no) 2009-04-29
JP2010504930A (ja) 2010-02-18
KR20090079914A (ko) 2009-07-22
PT2066659E (pt) 2013-11-07
CO6170358A2 (es) 2010-06-18
US20100324009A1 (en) 2010-12-23
AU2007304475B2 (en) 2012-07-26
US20080153843A1 (en) 2008-06-26
NZ575566A (en) 2011-05-27
JP5405303B2 (ja) 2014-02-05
DK2066659T3 (da) 2013-12-09
BRPI0714764A2 (pt) 2014-12-30
CY1114669T1 (el) 2016-10-05
ZA200902915B (en) 2010-02-24
IL197814A0 (en) 2009-12-24

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Effective date: 20140928