ES2401855T3 - Compuestos heterocíclicos, activos como inhibidores de beta-lactamasas - Google Patents

Compuestos heterocíclicos, activos como inhibidores de beta-lactamasas Download PDF

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Publication number
ES2401855T3
ES2401855T3 ES10177533T ES10177533T ES2401855T3 ES 2401855 T3 ES2401855 T3 ES 2401855T3 ES 10177533 T ES10177533 T ES 10177533T ES 10177533 T ES10177533 T ES 10177533T ES 2401855 T3 ES2401855 T3 ES 2401855T3
Authority
ES
Spain
Prior art keywords
oxo
trans
diazabicyclo
octane
sulfooxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES10177533T
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English (en)
Spanish (es)
Inventor
Jozsef Aszodi
Claude Fromentin
Maxime Lampilas
David Alun Rowlands
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Novexel SA
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Novexel SA
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Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27619669&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2401855(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novexel SA filed Critical Novexel SA
Application granted granted Critical
Publication of ES2401855T3 publication Critical patent/ES2401855T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES10177533T 2002-01-28 2003-01-27 Compuestos heterocíclicos, activos como inhibidores de beta-lactamasas Expired - Lifetime ES2401855T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0200951A FR2835186B1 (fr) 2002-01-28 2002-01-28 Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases
FR0200951 2002-01-28

Publications (1)

Publication Number Publication Date
ES2401855T3 true ES2401855T3 (es) 2013-04-25

Family

ID=27619669

Family Applications (2)

Application Number Title Priority Date Filing Date
ES10177533T Expired - Lifetime ES2401855T3 (es) 2002-01-28 2003-01-27 Compuestos heterocíclicos, activos como inhibidores de beta-lactamasas
ES03709903T Expired - Lifetime ES2356813T3 (es) 2002-01-28 2003-01-27 Nuevos compuestos heterocíclicos, activos como inhibidores de beta-lactamasas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES03709903T Expired - Lifetime ES2356813T3 (es) 2002-01-28 2003-01-27 Nuevos compuestos heterocíclicos, activos como inhibidores de beta-lactamasas.

Country Status (44)

Country Link
US (4) US7612087B2 (OSRAM)
EP (2) EP1480644B1 (OSRAM)
JP (1) JP4472346B2 (OSRAM)
KR (1) KR100979079B1 (OSRAM)
CN (3) CN100482225C (OSRAM)
AR (2) AR038234A1 (OSRAM)
AT (1) ATE484281T1 (OSRAM)
AU (1) AU2003214335B2 (OSRAM)
BE (1) BE2016C069I2 (OSRAM)
BR (1) BRPI0307267B8 (OSRAM)
CA (1) CA2474043C (OSRAM)
CL (1) CL2011000009A1 (OSRAM)
CO (1) CO5601014A2 (OSRAM)
CR (2) CR7387A (OSRAM)
CY (3) CY1111061T1 (OSRAM)
DE (1) DE60334527D1 (OSRAM)
DK (2) DK2279737T3 (OSRAM)
EA (1) EA007220B1 (OSRAM)
EC (1) ECSP045193A (OSRAM)
ES (2) ES2401855T3 (OSRAM)
FR (2) FR2835186B1 (OSRAM)
HR (1) HRP20040686B1 (OSRAM)
HU (1) HUS1600055I1 (OSRAM)
IL (1) IL163167A (OSRAM)
JO (1) JO2646B1 (OSRAM)
LT (1) LTC1480644I2 (OSRAM)
MA (1) MA26351A1 (OSRAM)
MX (1) MXPA04006621A (OSRAM)
MY (1) MY140638A (OSRAM)
NL (1) NL300847I2 (OSRAM)
NO (3) NO335195B1 (OSRAM)
NZ (1) NZ533936A (OSRAM)
OA (1) OA12761A (OSRAM)
PE (1) PE20030969A1 (OSRAM)
PL (1) PL220725B1 (OSRAM)
PT (2) PT1480644E (OSRAM)
RS (1) RS52137B (OSRAM)
SI (2) SI2279737T1 (OSRAM)
TN (1) TNSN04137A1 (OSRAM)
TW (1) TWI293071B (OSRAM)
UA (1) UA80271C2 (OSRAM)
UY (1) UY27626A1 (OSRAM)
WO (1) WO2003063864A2 (OSRAM)
ZA (1) ZA200405607B (OSRAM)

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FR2844273B1 (fr) 2002-09-05 2008-04-04 Aventis Pharma Sa Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
US7439253B2 (en) * 2002-12-06 2008-10-21 Novexel Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
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