ES2361995T5 - Filtros para separar leucocitos de la sangre entera /o preparados de la sangre, procedimiento para la fabricación de estos filtros, dispositivo y utilización - Google Patents
Filtros para separar leucocitos de la sangre entera /o preparados de la sangre, procedimiento para la fabricación de estos filtros, dispositivo y utilización Download PDFInfo
- Publication number
- ES2361995T5 ES2361995T5 ES04704209.8T ES04704209T ES2361995T5 ES 2361995 T5 ES2361995 T5 ES 2361995T5 ES 04704209 T ES04704209 T ES 04704209T ES 2361995 T5 ES2361995 T5 ES 2361995T5
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- Spain
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- Expired - Lifetime
Links
- 210000004369 blood Anatomy 0.000 title claims abstract description 37
- 239000008280 blood Substances 0.000 title claims abstract description 37
- 210000000265 leukocyte Anatomy 0.000 title claims abstract description 28
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 11
- 238000000034 method Methods 0.000 title claims description 15
- 238000002360 preparation method Methods 0.000 title claims description 10
- 239000000463 material Substances 0.000 claims abstract description 66
- 239000011248 coating agent Substances 0.000 claims abstract description 44
- 238000000576 coating method Methods 0.000 claims abstract description 44
- 239000000178 monomer Substances 0.000 claims abstract description 39
- 230000002209 hydrophobic effect Effects 0.000 claims abstract description 25
- 239000000203 mixture Substances 0.000 claims abstract description 9
- 238000000926 separation method Methods 0.000 claims abstract description 7
- 238000009736 wetting Methods 0.000 claims abstract description 7
- 229920000642 polymer Polymers 0.000 claims description 29
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 26
- 239000000758 substrate Substances 0.000 claims description 23
- 239000000835 fiber Substances 0.000 claims description 14
- 239000002904 solvent Substances 0.000 claims description 8
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 claims description 7
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims description 6
- 229920000728 polyester Polymers 0.000 claims description 6
- 229920006301 statistical copolymer Polymers 0.000 claims description 6
- 238000001556 precipitation Methods 0.000 claims description 4
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims description 3
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 3
- 238000010526 radical polymerization reaction Methods 0.000 claims description 3
- 125000003010 ionic group Chemical group 0.000 claims description 2
- HLJDOURGTRAFHE-UHFFFAOYSA-N isocyanic acid;3,5,5-trimethylcyclohex-2-en-1-one Chemical compound N=C=O.N=C=O.CC1=CC(=O)CC(C)(C)C1 HLJDOURGTRAFHE-UHFFFAOYSA-N 0.000 claims description 2
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 claims 1
- 238000006116 polymerization reaction Methods 0.000 abstract 1
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 10
- 210000001772 blood platelet Anatomy 0.000 description 9
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 9
- 238000001914 filtration Methods 0.000 description 8
- 230000003647 oxidation Effects 0.000 description 8
- 238000007254 oxidation reaction Methods 0.000 description 8
- -1 polyethylene terephthalate Polymers 0.000 description 6
- 238000005227 gel permeation chromatography Methods 0.000 description 5
- 230000035699 permeability Effects 0.000 description 5
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 4
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 4
- KKEYFWRCBNTPAC-UHFFFAOYSA-N Terephthalic acid Chemical compound OC(=O)C1=CC=C(C(O)=O)C=C1 KKEYFWRCBNTPAC-UHFFFAOYSA-N 0.000 description 4
- 238000004132 cross linking Methods 0.000 description 4
- 229910052740 iodine Inorganic materials 0.000 description 4
- 239000011630 iodine Substances 0.000 description 4
- 229920001707 polybutylene terephthalate Polymers 0.000 description 4
- 229920000139 polyethylene terephthalate Polymers 0.000 description 4
- 239000005020 polyethylene terephthalate Substances 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 210000003743 erythrocyte Anatomy 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 239000012528 membrane Substances 0.000 description 3
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 description 3
- ZGEGCLOFRBLKSE-UHFFFAOYSA-N 1-Heptene Chemical compound CCCCCC=C ZGEGCLOFRBLKSE-UHFFFAOYSA-N 0.000 description 2
- OZAIFHULBGXAKX-UHFFFAOYSA-N 2-(2-cyanopropan-2-yldiazenyl)-2-methylpropanenitrile Chemical compound N#CC(C)(C)N=NC(C)(C)C#N OZAIFHULBGXAKX-UHFFFAOYSA-N 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 2
- BAPJBEWLBFYGME-UHFFFAOYSA-N Methyl acrylate Chemical compound COC(=O)C=C BAPJBEWLBFYGME-UHFFFAOYSA-N 0.000 description 2
- 239000000020 Nitrocellulose Substances 0.000 description 2
- 239000004952 Polyamide Substances 0.000 description 2
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 150000001336 alkenes Chemical class 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 239000012503 blood component Substances 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 229920001600 hydrophobic polymer Polymers 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 229920001220 nitrocellulos Polymers 0.000 description 2
- 239000012299 nitrogen atmosphere Substances 0.000 description 2
- 239000003960 organic solvent Substances 0.000 description 2
- 230000002572 peristaltic effect Effects 0.000 description 2
- 229920002647 polyamide Polymers 0.000 description 2
- 229920000515 polycarbonate Polymers 0.000 description 2
- 239000004417 polycarbonate Substances 0.000 description 2
- 238000006068 polycondensation reaction Methods 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 229920002215 polytrimethylene terephthalate Polymers 0.000 description 2
- 239000012286 potassium permanganate Substances 0.000 description 2
- 239000011541 reaction mixture Substances 0.000 description 2
- 238000010992 reflux Methods 0.000 description 2
- AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 2
- 235000019345 sodium thiosulphate Nutrition 0.000 description 2
- 239000003634 thrombocyte concentrate Substances 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 description 1
- WHNBDXQTMPYBAT-UHFFFAOYSA-N 2-butyloxirane Chemical compound CCCCC1CO1 WHNBDXQTMPYBAT-UHFFFAOYSA-N 0.000 description 1
- MUZDXNQOSGWMJJ-UHFFFAOYSA-N 2-methylprop-2-enoic acid;prop-2-enoic acid Chemical class OC(=O)C=C.CC(=C)C(O)=O MUZDXNQOSGWMJJ-UHFFFAOYSA-N 0.000 description 1
- YHQXBTXEYZIYOV-UHFFFAOYSA-N 3-methylbut-1-ene Chemical compound CC(C)C=C YHQXBTXEYZIYOV-UHFFFAOYSA-N 0.000 description 1
- WSSSPWUEQFSQQG-UHFFFAOYSA-N 4-methyl-1-pentene Chemical compound CC(C)CC=C WSSSPWUEQFSQQG-UHFFFAOYSA-N 0.000 description 1
- UNMYWSMUMWPJLR-UHFFFAOYSA-L Calcium iodide Chemical compound [Ca+2].[I-].[I-] UNMYWSMUMWPJLR-UHFFFAOYSA-L 0.000 description 1
- 230000005526 G1 to G0 transition Effects 0.000 description 1
- 239000005057 Hexamethylene diisocyanate Substances 0.000 description 1
- 206010053317 Hydrophobia Diseases 0.000 description 1
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 206010037742 Rabies Diseases 0.000 description 1
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 1
- 238000004833 X-ray photoelectron spectroscopy Methods 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 150000001335 aliphatic alkanes Chemical class 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 125000003368 amide group Chemical group 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 229940046413 calcium iodide Drugs 0.000 description 1
- 229910001640 calcium iodide Inorganic materials 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000000306 component Substances 0.000 description 1
- 239000003431 cross linking reagent Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- LDLDYFCCDKENPD-UHFFFAOYSA-N ethenylcyclohexane Chemical compound C=CC1CCCCC1 LDLDYFCCDKENPD-UHFFFAOYSA-N 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229920000578 graft copolymer Polymers 0.000 description 1
- ZRALSGWEFCBTJO-UHFFFAOYSA-N guanidine group Chemical group NC(=N)N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 description 1
- RRAMGCGOFNQTLD-UHFFFAOYSA-N hexamethylene diisocyanate Chemical compound O=C=NCCCCCCN=C=O RRAMGCGOFNQTLD-UHFFFAOYSA-N 0.000 description 1
- XXMIOPMDWAUFGU-UHFFFAOYSA-N hexane-1,6-diol Chemical compound OCCCCCCO XXMIOPMDWAUFGU-UHFFFAOYSA-N 0.000 description 1
- 150000002430 hydrocarbons Chemical group 0.000 description 1
- 229920001477 hydrophilic polymer Polymers 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 230000008105 immune reaction Effects 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 150000003951 lactams Chemical class 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000012476 oxidizable substance Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- UEZVMMHDMIWARA-UHFFFAOYSA-M phosphonate Chemical compound [O-]P(=O)=O UEZVMMHDMIWARA-UHFFFAOYSA-M 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- SBMSLRMNBSMKQC-UHFFFAOYSA-N pyrrolidin-1-amine Chemical compound NN1CCCC1 SBMSLRMNBSMKQC-UHFFFAOYSA-N 0.000 description 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 229920001567 vinyl ester resin Polymers 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D39/00—Filtering material for liquid or gaseous fluids
- B01D39/14—Other self-supporting filtering material ; Other filtering material
- B01D39/16—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres
- B01D39/1607—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being fibrous
- B01D39/1623—Other self-supporting filtering material ; Other filtering material of organic material, e.g. synthetic fibres the material being fibrous of synthetic origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
- A61M1/3633—Blood component filters, e.g. leukocyte filters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2239/00—Aspects relating to filtering material for liquid or gaseous fluids
- B01D2239/04—Additives and treatments of the filtering material
- B01D2239/0471—Surface coating material
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
- Filtering Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Reinforced Plastic Materials (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITTO03A0039 | 2003-01-24 | ||
| IT000039A ITTO20030039A1 (it) | 2003-01-24 | 2003-01-24 | Filtro per separare leucociti da sangue intero e/o da preparati derivati dal sangue, procedimento per la fabbricazione del filtro, dispositivo e utilizzazione. |
| ITTO20030039 | 2003-01-24 | ||
| PCT/EP2004/000489 WO2004064980A1 (de) | 2003-01-24 | 2004-01-22 | Filter zur abtrennung von leukozyten aus vollblut/oder blutpräparaten, verfahren zur herstellung dieser filter, vorrichtung und verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2361995T3 ES2361995T3 (es) | 2011-06-27 |
| ES2361995T5 true ES2361995T5 (es) | 2015-02-11 |
Family
ID=32750533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES04704209.8T Expired - Lifetime ES2361995T5 (es) | 2003-01-24 | 2004-01-22 | Filtros para separar leucocitos de la sangre entera /o preparados de la sangre, procedimiento para la fabricación de estos filtros, dispositivo y utilización |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7775376B2 (https=) |
| EP (1) | EP1590065B2 (https=) |
| JP (1) | JP4394676B2 (https=) |
| CN (1) | CN100475307C (https=) |
| AT (1) | ATE505250T1 (https=) |
| DE (1) | DE502004012398D1 (https=) |
| ES (1) | ES2361995T5 (https=) |
| IT (1) | ITTO20030039A1 (https=) |
| PT (1) | PT1590065E (https=) |
| WO (1) | WO2004064980A1 (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20050036848A (ko) * | 2001-10-16 | 2005-04-20 | 아사히 카세이 메디칼 가부시키가이샤 | 바이러스 및 백혈구의 선택적 제거 방법, 제거재 및 제거장치 |
| US8828226B2 (en) | 2003-03-01 | 2014-09-09 | The Trustees Of Boston University | System for assessing the efficacy of stored red blood cells using microvascular networks |
| EP1785431B1 (en) * | 2004-08-30 | 2016-01-20 | Toray Industries, Inc. | Fractionation apparatus |
| FR2892949B1 (fr) * | 2005-11-08 | 2008-05-16 | Maco Pharma Sa | Unite de filtration des leucocytes a adhesion des plaquettes reduites |
| FR2925352B1 (fr) | 2007-12-21 | 2010-02-26 | Maco Pharma Sa | Procede de greffage d'un element poreux pour la deleucocytation |
| US11284616B2 (en) | 2010-05-05 | 2022-03-29 | Hemanext Inc. | Irradiation of red blood cells and anaerobic storage |
| CN102905522A (zh) | 2009-10-12 | 2013-01-30 | 新健康科学股份有限公司 | 用于从红细胞中除去氧的氧消耗装置和方法 |
| US9199016B2 (en) | 2009-10-12 | 2015-12-01 | New Health Sciences, Inc. | System for extended storage of red blood cells and methods of use |
| US12089589B2 (en) | 2009-10-12 | 2024-09-17 | Hemanext Inc. | Irradiation of red blood cells and anaerobic storage |
| CA2781866C (en) | 2009-10-12 | 2019-12-03 | New Health Sciences, Inc. | Blood storage bag system and depletion devices with oxygen and carbon dioxide depletion capabilities |
| US9339025B2 (en) | 2010-08-25 | 2016-05-17 | New Health Sciences, Inc. | Method for enhancing red blood cell quality and survival during storage |
| PT2635114T (pt) | 2010-11-05 | 2020-06-16 | New Health Sciences Inc | Irradiação de glóbulos vermelhos e armazenamento anaeróbico |
| RU2465951C1 (ru) * | 2011-03-01 | 2012-11-10 | Закрытое Акционерное Общество "Аквафор Продакшн" (Зао "Аквафор Продакшн") | Композиционный материал для фильтрационной очистки жидкости |
| US9067004B2 (en) | 2011-03-28 | 2015-06-30 | New Health Sciences, Inc. | Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly |
| ES2984863T3 (es) | 2011-08-10 | 2024-10-31 | Hemanext Inc | Dispositivo integrado de filtrado de leucocitos, oxígeno y/o agotamiento de CO2, y separación de plasma |
| JP2014061502A (ja) * | 2012-09-24 | 2014-04-10 | Mitsubishi Paper Mills Ltd | フィルタ用不織布及びフィルタ用濾材 |
| ES2900298T3 (es) | 2013-02-28 | 2022-03-16 | Hemanext Inc | Dispositivo de agotamiento de gas para productos sanguíneos |
| FR3003764B1 (fr) | 2013-03-27 | 2015-05-01 | Maco Pharma Sa | Unite de filtration des leucocytes a adhesion des plaquettes reduite |
| US20140367324A1 (en) * | 2013-06-15 | 2014-12-18 | Fenwal, Inc. | Coatings for biological fluid filters |
| JP2015062870A (ja) * | 2013-09-25 | 2015-04-09 | 住友電気工業株式会社 | 濾過膜、濾過ユニット並びに濾過システム及び濾過方法 |
| US10376627B2 (en) | 2014-03-24 | 2019-08-13 | Fenwal, Inc. | Flexible biological fluid filters |
| US9968738B2 (en) | 2014-03-24 | 2018-05-15 | Fenwal, Inc. | Biological fluid filters with molded frame and methods for making such filters |
| US9782707B2 (en) | 2014-03-24 | 2017-10-10 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
| US10159778B2 (en) | 2014-03-24 | 2018-12-25 | Fenwal, Inc. | Biological fluid filters having flexible walls and methods for making such filters |
| US9796166B2 (en) | 2014-03-24 | 2017-10-24 | Fenwal, Inc. | Flexible biological fluid filters |
| EP3185926B1 (de) | 2014-08-26 | 2018-11-28 | 3M Innovative Properties Company | System zur entfernung von proinflammatorischen mediatoren sowie von granulozyten und monozyten aus blut |
| WO2016073415A2 (en) | 2014-11-04 | 2016-05-12 | Wainamics, Inc. | Microscale plasma separator |
| CN106178638A (zh) * | 2015-03-03 | 2016-12-07 | 张家港高力特医疗器械有限公司 | 过滤器 |
| PT3970731T (pt) | 2015-03-10 | 2026-02-24 | Hemanext Inc | Kits descartáveis de redução de oxigénio, dispositivos e métodos de utilização dos mesmos |
| WO2016172645A1 (en) | 2015-04-23 | 2016-10-27 | New Health Sciences, Inc. | Anaerobic blood storage containers |
| CA2985799A1 (en) | 2015-05-18 | 2016-11-24 | New Health Sciences, Inc. | Methods for the storage of whole blood, and compositions thereof |
| US10814051B2 (en) * | 2015-06-17 | 2020-10-27 | Asahi Kasei Medical Co., Ltd. | Filter element for blood processing filter and blood processing filter |
| US10722848B2 (en) * | 2015-10-23 | 2020-07-28 | 3M Innovative Properties Company | Filtration medium sequence for biomaterial purification |
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| JP7264368B2 (ja) * | 2019-01-29 | 2023-04-25 | 株式会社日本触媒 | 繊維強化材料、及び繊維強化材料の製造方法 |
| US11224858B1 (en) | 2020-10-01 | 2022-01-18 | Immunicom, Inc. | Reduced leaching of a ligand |
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| US5162102A (en) | 1987-09-21 | 1992-11-10 | Terumo Kabushiki Kaisha | Medical instrument and production thereof |
| IL88081A0 (en) * | 1987-10-20 | 1989-06-30 | Pall Corp | Device and method for depletion of the leucocyte content of blood and blood components |
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| US4880548A (en) | 1988-02-17 | 1989-11-14 | Pall Corporation | Device and method for separating leucocytes from platelet concentrate |
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| EP0869835B1 (en) | 1995-04-13 | 2005-06-08 | Travenol Laboratories (Israel) Ltd. | Leukocyte filtration method and apparatus |
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| US6437040B2 (en) * | 1999-09-01 | 2002-08-20 | Rhodia Chimie | Water-soluble block copolymers comprising a hydrophilic block and a hydrophobic block |
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-
2003
- 2003-01-24 IT IT000039A patent/ITTO20030039A1/it unknown
-
2004
- 2004-01-22 PT PT04704209T patent/PT1590065E/pt unknown
- 2004-01-22 DE DE502004012398T patent/DE502004012398D1/de not_active Expired - Lifetime
- 2004-01-22 CN CNB2004800026735A patent/CN100475307C/zh not_active Expired - Lifetime
- 2004-01-22 WO PCT/EP2004/000489 patent/WO2004064980A1/de not_active Ceased
- 2004-01-22 AT AT04704209T patent/ATE505250T1/de active
- 2004-01-22 US US10/543,444 patent/US7775376B2/en not_active Expired - Lifetime
- 2004-01-22 EP EP04704209.8A patent/EP1590065B2/de not_active Expired - Lifetime
- 2004-01-22 ES ES04704209.8T patent/ES2361995T5/es not_active Expired - Lifetime
- 2004-01-22 JP JP2006500005A patent/JP4394676B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP4394676B2 (ja) | 2010-01-06 |
| CN1741839A (zh) | 2006-03-01 |
| DE502004012398D1 (de) | 2011-05-26 |
| ATE505250T1 (de) | 2011-04-15 |
| WO2004064980A1 (de) | 2004-08-05 |
| ITTO20030039A1 (it) | 2004-07-25 |
| PT1590065E (pt) | 2011-05-26 |
| EP1590065B1 (de) | 2011-04-13 |
| US20060207937A1 (en) | 2006-09-21 |
| EP1590065A1 (de) | 2005-11-02 |
| US7775376B2 (en) | 2010-08-17 |
| EP1590065B2 (de) | 2014-10-29 |
| JP2006518420A (ja) | 2006-08-10 |
| ES2361995T3 (es) | 2011-06-27 |
| CN100475307C (zh) | 2009-04-08 |
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