ES2346216T3 - Derivados de quelidonina cuaternaria y de alcaloides, procedimiento para su preparacion y su uso en la preparacion de medicamentos. - Google Patents
Derivados de quelidonina cuaternaria y de alcaloides, procedimiento para su preparacion y su uso en la preparacion de medicamentos. Download PDFInfo
- Publication number
- ES2346216T3 ES2346216T3 ES04719983T ES04719983T ES2346216T3 ES 2346216 T3 ES2346216 T3 ES 2346216T3 ES 04719983 T ES04719983 T ES 04719983T ES 04719983 T ES04719983 T ES 04719983T ES 2346216 T3 ES2346216 T3 ES 2346216T3
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- Prior art keywords
- alkaloid
- derivative
- reaction
- krs
- alkaloids
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- Expired - Lifetime
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- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
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- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
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- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/564—Three-membered rings
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- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
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- Medicinal Chemistry (AREA)
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- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03006015 | 2003-03-18 | ||
| EP03006015A EP1459753A1 (en) | 2003-03-18 | 2003-03-18 | Quaternary chelidonine and alkaloid derivatives, process for their preparation and their use in the manufacture of medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2346216T3 true ES2346216T3 (es) | 2010-10-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES04719983T Expired - Lifetime ES2346216T3 (es) | 2003-03-18 | 2004-03-12 | Derivados de quelidonina cuaternaria y de alcaloides, procedimiento para su preparacion y su uso en la preparacion de medicamentos. |
Country Status (36)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20080284A1 (it) * | 2008-02-22 | 2009-08-23 | Indena Spa | Agenti antitumorali a struttura benzofenantridinica e formulazioni che li contengono |
| US8835506B2 (en) | 2008-06-05 | 2014-09-16 | Stc.Unm | Methods and related compositions for the treatment of cancer |
| CN102552264A (zh) * | 2012-02-28 | 2012-07-11 | 苏州大学 | 血根碱在制备电离辐射防护剂中的应用 |
| US20240139162A1 (en) * | 2019-10-17 | 2024-05-02 | Chengdu Anticancer Bioscience, Ltd. | Benzophenanthridine Alkaloids and Their Methods of Use |
| CN113372355B (zh) * | 2021-05-13 | 2023-02-17 | 山东大学 | 六氢苯并菲啶类生物碱及其制备方法和应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU368254A1 (ru) | 1969-06-16 | 1973-01-26 | А. И. Потопальский , В. М. Новицкий Львовский государственный медицинский институт | Способ получения соединений тиофосфамида с алкалоидами чистотела большого |
| US3865830A (en) * | 1969-06-16 | 1975-02-11 | Nikolai Mikhailovich Turkevich | Thiophosphamide derivatives of isoquinoline alkaloids, method of producing and application thereof |
| AT354644B (de) | 1975-12-19 | 1980-01-25 | Nowicky Wassili | Verfahren zur herstellung von neuen salzen von alkaloidderivaten von thiophosphorsaeure |
| AT377988B (de) * | 1976-06-28 | 1985-05-28 | Nowicky Wassili | Verfahren zur herstellung von neuen phosphorderivaten von alkaloiden |
| DE3128018A1 (de) | 1981-07-13 | 1983-04-07 | Wassyl 1060 Wien Nowicky | "verfahren zum diagnostizieren und fuer die therapeutische behandlung von tumoren und/oder infektioesen krankheiten verschiedenster art unter praeparativem einsatz von alkaloid-verbindungen bzw. deren salze" |
| US4970212A (en) | 1982-05-18 | 1990-11-13 | Nowicky Wassili | Method of treating human illnesses which compromise the ability to mount an effective immunological response |
| AT407833B (de) * | 1995-06-01 | 2001-06-25 | Nowicky Wassyl Dr | Mittel zur behandlung von strahlenschäden |
| AT408719B (de) | 2000-03-22 | 2002-02-25 | Nowicky Wassili | Mittel zur behandlung von hepatitis c |
| CH695417A5 (de) | 2001-11-15 | 2006-05-15 | Ddr Wassyl Nowicky Dipl Ing | Verfahren zur Umsetzung von Alkaloiden. |
-
2003
- 2003-03-18 EP EP03006015A patent/EP1459753A1/en not_active Withdrawn
- 2003-06-19 CN CNA031373550A patent/CN1532198A/zh active Pending
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2004
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- 2004-03-12 HR HRP20050987AA patent/HRP20050987B1/hr not_active IP Right Cessation
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- 2004-03-12 JP JP2006504683A patent/JP5303719B2/ja not_active Expired - Fee Related
- 2004-03-12 KR KR1020057017086A patent/KR101020680B1/ko not_active Expired - Fee Related
- 2004-03-12 BR BRPI0408386-5A patent/BRPI0408386A/pt not_active IP Right Cessation
- 2004-03-12 ES ES04719983T patent/ES2346216T3/es not_active Expired - Lifetime
- 2004-03-12 PT PT04719983T patent/PT1644012E/pt unknown
- 2004-03-12 AU AU2004222661A patent/AU2004222661B2/en not_active Ceased
- 2004-03-12 WO PCT/EP2004/002637 patent/WO2004082698A1/en not_active Ceased
- 2004-03-12 SG SG200706589-9A patent/SG158748A1/en unknown
- 2004-03-12 MX MXPA05009919A patent/MXPA05009919A/es active IP Right Grant
- 2004-03-12 US US10/549,433 patent/US7795434B2/en not_active Expired - Fee Related
- 2004-03-12 PL PL04719983T patent/PL1644012T3/pl unknown
- 2004-03-12 DE DE602004027496T patent/DE602004027496D1/de not_active Expired - Lifetime
- 2004-03-12 DK DK04719983.1T patent/DK1644012T3/da active
- 2004-03-12 EP EP04719983A patent/EP1644012B1/en not_active Expired - Lifetime
- 2004-03-12 SI SI200431489T patent/SI1644012T1/sl unknown
- 2004-03-12 AT AT04719983T patent/ATE469651T1/de active
- 2004-03-12 ZA ZA200507020A patent/ZA200507020B/en unknown
- 2004-03-12 GE GEAP20048963A patent/GEP20084501B/en unknown
- 2004-03-12 EA EA200501473A patent/EA009049B1/ru not_active IP Right Cessation
- 2004-03-16 MY MYPI20040919A patent/MY141779A/en unknown
- 2004-03-17 PE PE2004000281A patent/PE20050351A1/es not_active Application Discontinuation
- 2004-03-17 CL CL200400552A patent/CL2004000552A1/es unknown
- 2004-03-17 AR ARP040100877A patent/AR043629A1/es not_active Application Discontinuation
- 2004-03-18 TW TW093107196A patent/TWI347939B/zh not_active IP Right Cessation
- 2004-03-18 PA PA20048598201A patent/PA8598201A1/es unknown
- 2004-03-18 GT GT200400046A patent/GT200400046A/es unknown
- 2004-12-03 UA UAA200509763A patent/UA89353C2/uk unknown
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2005
- 2005-08-25 IL IL170505A patent/IL170505A/en not_active IP Right Cessation
- 2005-09-06 NO NO20054130A patent/NO333672B1/no not_active IP Right Cessation
- 2005-09-16 TN TNP2005000230A patent/TNSN05230A1/en unknown
- 2005-10-17 MA MA28556A patent/MA27833A1/fr unknown
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2008
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2010
- 2010-08-20 CY CY20101100773T patent/CY1112598T1/el unknown
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