ES2281915T3 - Proteina tirosina fosfatasas de captura de sustrato. - Google Patents

Proteina tirosina fosfatasas de captura de sustrato. Download PDF

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Publication number
ES2281915T3
ES2281915T3 ES97937017T ES97937017T ES2281915T3 ES 2281915 T3 ES2281915 T3 ES 2281915T3 ES 97937017 T ES97937017 T ES 97937017T ES 97937017 T ES97937017 T ES 97937017T ES 2281915 T3 ES2281915 T3 ES 2281915T3
Authority
ES
Spain
Prior art keywords
protein
tyrosine
ptp
baselineskip
phosphorylated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97937017T
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English (en)
Spanish (es)
Inventor
Nicholas Tonks
Andrew J. Flint
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cold Spring Harbor Laboratory
Original Assignee
Cold Spring Harbor Laboratory
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Filing date
Publication date
Application filed by Cold Spring Harbor Laboratory filed Critical Cold Spring Harbor Laboratory
Application granted granted Critical
Publication of ES2281915T3 publication Critical patent/ES2281915T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Alcoholic Beverages (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ES97937017T 1996-07-25 1997-07-24 Proteina tirosina fosfatasas de captura de sustrato. Expired - Lifetime ES2281915T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US685992 1996-07-25
US08/685,992 US5912138A (en) 1996-07-25 1996-07-25 Substrate trapping protein tyrosine phosphatases

Publications (1)

Publication Number Publication Date
ES2281915T3 true ES2281915T3 (es) 2007-10-01

Family

ID=24754471

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97937017T Expired - Lifetime ES2281915T3 (es) 1996-07-25 1997-07-24 Proteina tirosina fosfatasas de captura de sustrato.

Country Status (9)

Country Link
US (2) US5912138A (enExample)
EP (1) EP0918867B1 (enExample)
JP (1) JP2000515760A (enExample)
AT (1) ATE352625T1 (enExample)
AU (1) AU728405B2 (enExample)
CA (1) CA2262440A1 (enExample)
DE (1) DE69737290T2 (enExample)
ES (1) ES2281915T3 (enExample)
WO (1) WO1998004712A2 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891646A (en) * 1997-06-05 1999-04-06 Duke University Methods of assaying receptor activity and constructs useful in such methods
US7541151B2 (en) 1997-06-05 2009-06-02 Duke University Single-cell biosensor for the measurement of GPCR ligands in a test sample
US6528271B1 (en) * 1997-06-05 2003-03-04 Duke University Inhibition of βarrestin mediated effects prolongs and potentiates opioid receptor-mediated analgesia
EP1077997A2 (en) * 1998-05-21 2001-02-28 THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING (McGILL UNIVERSITY) Inhibition of the binding of protein tyrosine phosphatase pest to domains of signalling proteins
US6156551A (en) * 1998-06-05 2000-12-05 Beth Israel Deaconess Medical Center Activated mutants of SH2-domain-containing protein tyrosine phosphatases and methods of use thereof
US6248327B1 (en) 1998-09-11 2001-06-19 Vanderbilt University Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
US7176289B1 (en) 1998-09-11 2007-02-13 Vanderbilt University Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
US6355786B1 (en) 1998-10-30 2002-03-12 Vanderbilt University Purified and isolated protein zero related (PZR) and therapeutic and screening methods using same
JP2002537854A (ja) 1999-03-08 2002-11-12 メルク フロスト カナダ アンド カンパニー タンパク質チロシンホスファターゼの無傷細胞アッセイ
US6852520B1 (en) 1999-03-24 2005-02-08 Ceptyr, Inc. DSP-2 dual-specificity phosphatase
US6841369B1 (en) 1999-04-07 2005-01-11 Ceptyr, Inc. DSP-4 dual specificity phosphatase
US6492157B1 (en) 1999-04-07 2002-12-10 Ceptyr, Inc. DSP-9 dual-specificity phosphatase
EP1173587A1 (en) 1999-04-23 2002-01-23 Ceptyr, Inc. Dsp-10 dual-specificity map kinase phosphatase
US6645753B1 (en) 1999-04-27 2003-11-11 Ceptyr, Inc. DSP-5 dual-specificity phosphatase
AU5284200A (en) * 1999-06-03 2000-12-28 Cold Spring Harbor Laboratory Substrate trapping protein tyrosine phosphatases
US7078210B2 (en) 1999-07-02 2006-07-18 Ceptyr, Inc. DSP-3 dual-specificity phosphatase
WO2001005983A1 (en) 1999-07-20 2001-01-25 Ceptyr, Inc. Dsp-11 dual-specificity map kinase phosphatase
WO2001057221A2 (en) 2000-02-02 2001-08-09 Ceptyr, Inc. Dsp-12 and dsp-13 dual-specificity phosphatases
CA2435507A1 (en) * 2000-02-14 2001-08-23 Ceptyr, Inc. Improved assay for protein tyrosine phosphatases
US6825021B2 (en) 2000-09-19 2004-11-30 Ceptyr, Inc. DSP-15 dual-specificity phosphatase
US8071348B2 (en) * 2002-01-14 2011-12-06 Albert Einstein College Of Medicine Of Yeshiva University Protein tyrosine phosphatase substrate-trapping double mutant and uses thereof
US20030215899A1 (en) * 2002-02-13 2003-11-20 Ceptyr, Inc. Reversible oxidation of protein tyrosine phosphatases
US20030182669A1 (en) * 2002-03-19 2003-09-25 Rockman Howard A. Phosphoinositide 3-kinase mediated inhibition of GPCRs
AU2003283951A1 (en) * 2002-05-23 2004-03-03 Ceptyr, Inc. Modulation of biological signal transduction by rna interference
US7290215B2 (en) * 2002-06-03 2007-10-30 Microsoft Corporation Dynamic wizard interface system and method
WO2004048549A2 (en) * 2002-11-26 2004-06-10 Cold Spring Harbor Laboratory Dep-1 receptor protein tyrosine phosphatase interacting proteins and related methods
US20070238129A1 (en) * 2006-03-29 2007-10-11 Moyer Susanne C Catalytically inactive enzymes for affinity binding
CA2779683A1 (en) * 2009-11-10 2011-05-19 Amgen Inc. Anti-c-mpl antibodies
CN113899902B (zh) * 2020-06-22 2024-10-29 上海科技大学 一种酪氨酸磷酸酶底物鉴定方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352660A (en) * 1991-10-31 1994-10-04 Mount Sinai Hospital Corporation Method for assaying for a substance that affects a SH2-phosphorylated ligand regulatory system
US5589375A (en) * 1992-10-06 1996-12-31 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E. V. PTP 1D: a novel protein tyrosine phosphatase
US5585233A (en) * 1993-03-23 1996-12-17 Max-Planck Gesellschaft Zur Forderung Der Wissenschaften E.V. PTP-S31: A novel protein tyrosine phosphatase
JPH09510861A (ja) * 1993-09-01 1997-11-04 ザ・ルドウィッグ・インスティチュート・フォー・キャンサー・リサーチ 新規な蛋白質チロシンホスファターゼに対するヌクレオチド配列の一次構造および機能性発現
US5744313A (en) * 1994-12-09 1998-04-28 The Regents Of The University Of California Assay employing novel protein domain which binds tyrosine phosphorylated proteins

Also Published As

Publication number Publication date
ATE352625T1 (de) 2007-02-15
US5912138A (en) 1999-06-15
EP0918867B1 (en) 2007-01-24
DE69737290T2 (de) 2007-11-08
JP2000515760A (ja) 2000-11-28
AU5939598A (en) 1999-02-16
WO1998004712A3 (en) 1998-03-12
AU728405B2 (en) 2001-01-11
DE69737290D1 (en) 2007-03-15
CA2262440A1 (en) 1998-02-05
EP0918867A2 (en) 1999-06-02
US5951979A (en) 1999-09-14
WO1998004712A2 (en) 1998-02-05

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