ATE352625T1 - Substrat fangende protein tyrosin phosphatase - Google Patents

Substrat fangende protein tyrosin phosphatase

Info

Publication number
ATE352625T1
ATE352625T1 AT97937017T AT97937017T ATE352625T1 AT E352625 T1 ATE352625 T1 AT E352625T1 AT 97937017 T AT97937017 T AT 97937017T AT 97937017 T AT97937017 T AT 97937017T AT E352625 T1 ATE352625 T1 AT E352625T1
Authority
AT
Austria
Prior art keywords
protein tyrosine
tyrosine phosphatase
substrate
substrate catching
catching protein
Prior art date
Application number
AT97937017T
Other languages
German (de)
English (en)
Inventor
Nicholas Tonks
Andrew J Flint
Original Assignee
Cold Spring Harbor Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cold Spring Harbor Lab filed Critical Cold Spring Harbor Lab
Application granted granted Critical
Publication of ATE352625T1 publication Critical patent/ATE352625T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Alcoholic Beverages (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT97937017T 1996-07-25 1997-07-24 Substrat fangende protein tyrosin phosphatase ATE352625T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/685,992 US5912138A (en) 1996-07-25 1996-07-25 Substrate trapping protein tyrosine phosphatases

Publications (1)

Publication Number Publication Date
ATE352625T1 true ATE352625T1 (de) 2007-02-15

Family

ID=24754471

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97937017T ATE352625T1 (de) 1996-07-25 1997-07-24 Substrat fangende protein tyrosin phosphatase

Country Status (9)

Country Link
US (2) US5912138A (enExample)
EP (1) EP0918867B1 (enExample)
JP (1) JP2000515760A (enExample)
AT (1) ATE352625T1 (enExample)
AU (1) AU728405B2 (enExample)
CA (1) CA2262440A1 (enExample)
DE (1) DE69737290T2 (enExample)
ES (1) ES2281915T3 (enExample)
WO (1) WO1998004712A2 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891646A (en) * 1997-06-05 1999-04-06 Duke University Methods of assaying receptor activity and constructs useful in such methods
US7541151B2 (en) 1997-06-05 2009-06-02 Duke University Single-cell biosensor for the measurement of GPCR ligands in a test sample
US6528271B1 (en) * 1997-06-05 2003-03-04 Duke University Inhibition of βarrestin mediated effects prolongs and potentiates opioid receptor-mediated analgesia
EP1077997A2 (en) * 1998-05-21 2001-02-28 THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING (McGILL UNIVERSITY) Inhibition of the binding of protein tyrosine phosphatase pest to domains of signalling proteins
US6156551A (en) * 1998-06-05 2000-12-05 Beth Israel Deaconess Medical Center Activated mutants of SH2-domain-containing protein tyrosine phosphatases and methods of use thereof
US6248327B1 (en) 1998-09-11 2001-06-19 Vanderbilt University Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
US7176289B1 (en) 1998-09-11 2007-02-13 Vanderbilt University Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
US6355786B1 (en) 1998-10-30 2002-03-12 Vanderbilt University Purified and isolated protein zero related (PZR) and therapeutic and screening methods using same
JP2002537854A (ja) 1999-03-08 2002-11-12 メルク フロスト カナダ アンド カンパニー タンパク質チロシンホスファターゼの無傷細胞アッセイ
US6852520B1 (en) 1999-03-24 2005-02-08 Ceptyr, Inc. DSP-2 dual-specificity phosphatase
US6841369B1 (en) 1999-04-07 2005-01-11 Ceptyr, Inc. DSP-4 dual specificity phosphatase
US6492157B1 (en) 1999-04-07 2002-12-10 Ceptyr, Inc. DSP-9 dual-specificity phosphatase
EP1173587A1 (en) 1999-04-23 2002-01-23 Ceptyr, Inc. Dsp-10 dual-specificity map kinase phosphatase
US6645753B1 (en) 1999-04-27 2003-11-11 Ceptyr, Inc. DSP-5 dual-specificity phosphatase
AU5284200A (en) * 1999-06-03 2000-12-28 Cold Spring Harbor Laboratory Substrate trapping protein tyrosine phosphatases
US7078210B2 (en) 1999-07-02 2006-07-18 Ceptyr, Inc. DSP-3 dual-specificity phosphatase
WO2001005983A1 (en) 1999-07-20 2001-01-25 Ceptyr, Inc. Dsp-11 dual-specificity map kinase phosphatase
WO2001057221A2 (en) 2000-02-02 2001-08-09 Ceptyr, Inc. Dsp-12 and dsp-13 dual-specificity phosphatases
CA2435507A1 (en) * 2000-02-14 2001-08-23 Ceptyr, Inc. Improved assay for protein tyrosine phosphatases
US6825021B2 (en) 2000-09-19 2004-11-30 Ceptyr, Inc. DSP-15 dual-specificity phosphatase
US8071348B2 (en) * 2002-01-14 2011-12-06 Albert Einstein College Of Medicine Of Yeshiva University Protein tyrosine phosphatase substrate-trapping double mutant and uses thereof
US20030215899A1 (en) * 2002-02-13 2003-11-20 Ceptyr, Inc. Reversible oxidation of protein tyrosine phosphatases
US20030182669A1 (en) * 2002-03-19 2003-09-25 Rockman Howard A. Phosphoinositide 3-kinase mediated inhibition of GPCRs
AU2003283951A1 (en) * 2002-05-23 2004-03-03 Ceptyr, Inc. Modulation of biological signal transduction by rna interference
US7290215B2 (en) * 2002-06-03 2007-10-30 Microsoft Corporation Dynamic wizard interface system and method
WO2004048549A2 (en) * 2002-11-26 2004-06-10 Cold Spring Harbor Laboratory Dep-1 receptor protein tyrosine phosphatase interacting proteins and related methods
US20070238129A1 (en) * 2006-03-29 2007-10-11 Moyer Susanne C Catalytically inactive enzymes for affinity binding
CA2779683A1 (en) * 2009-11-10 2011-05-19 Amgen Inc. Anti-c-mpl antibodies
CN113899902B (zh) * 2020-06-22 2024-10-29 上海科技大学 一种酪氨酸磷酸酶底物鉴定方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352660A (en) * 1991-10-31 1994-10-04 Mount Sinai Hospital Corporation Method for assaying for a substance that affects a SH2-phosphorylated ligand regulatory system
US5589375A (en) * 1992-10-06 1996-12-31 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E. V. PTP 1D: a novel protein tyrosine phosphatase
US5585233A (en) * 1993-03-23 1996-12-17 Max-Planck Gesellschaft Zur Forderung Der Wissenschaften E.V. PTP-S31: A novel protein tyrosine phosphatase
JPH09510861A (ja) * 1993-09-01 1997-11-04 ザ・ルドウィッグ・インスティチュート・フォー・キャンサー・リサーチ 新規な蛋白質チロシンホスファターゼに対するヌクレオチド配列の一次構造および機能性発現
US5744313A (en) * 1994-12-09 1998-04-28 The Regents Of The University Of California Assay employing novel protein domain which binds tyrosine phosphorylated proteins

Also Published As

Publication number Publication date
ES2281915T3 (es) 2007-10-01
US5912138A (en) 1999-06-15
EP0918867B1 (en) 2007-01-24
DE69737290T2 (de) 2007-11-08
JP2000515760A (ja) 2000-11-28
AU5939598A (en) 1999-02-16
WO1998004712A3 (en) 1998-03-12
AU728405B2 (en) 2001-01-11
DE69737290D1 (en) 2007-03-15
CA2262440A1 (en) 1998-02-05
EP0918867A2 (en) 1999-06-02
US5951979A (en) 1999-09-14
WO1998004712A2 (en) 1998-02-05

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