JP2000515760A - 基質トラッププロテインチロシンホスファターゼ - Google Patents
基質トラッププロテインチロシンホスファターゼInfo
- Publication number
- JP2000515760A JP2000515760A JP10508989A JP50898998A JP2000515760A JP 2000515760 A JP2000515760 A JP 2000515760A JP 10508989 A JP10508989 A JP 10508989A JP 50898998 A JP50898998 A JP 50898998A JP 2000515760 A JP2000515760 A JP 2000515760A
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- Prior art keywords
- protein
- ptp
- cas
- tyrosine
- pest
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Alcoholic Beverages (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/685,992 US5912138A (en) | 1996-07-25 | 1996-07-25 | Substrate trapping protein tyrosine phosphatases |
| US08/685,992 | 1996-07-25 | ||
| PCT/US1997/013016 WO1998004712A2 (en) | 1996-07-25 | 1997-07-24 | Substrate trapping protein tyrosine phosphatases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2000515760A true JP2000515760A (ja) | 2000-11-28 |
| JP2000515760A5 JP2000515760A5 (enExample) | 2005-04-07 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10508989A Pending JP2000515760A (ja) | 1996-07-25 | 1997-07-24 | 基質トラッププロテインチロシンホスファターゼ |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5912138A (enExample) |
| EP (1) | EP0918867B1 (enExample) |
| JP (1) | JP2000515760A (enExample) |
| AT (1) | ATE352625T1 (enExample) |
| AU (1) | AU728405B2 (enExample) |
| CA (1) | CA2262440A1 (enExample) |
| DE (1) | DE69737290T2 (enExample) |
| ES (1) | ES2281915T3 (enExample) |
| WO (1) | WO1998004712A2 (enExample) |
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| US6528271B1 (en) | 1997-06-05 | 2003-03-04 | Duke University | Inhibition of βarrestin mediated effects prolongs and potentiates opioid receptor-mediated analgesia |
| US7541151B2 (en) | 1997-06-05 | 2009-06-02 | Duke University | Single-cell biosensor for the measurement of GPCR ligands in a test sample |
| US5891646A (en) * | 1997-06-05 | 1999-04-06 | Duke University | Methods of assaying receptor activity and constructs useful in such methods |
| AU3922999A (en) * | 1998-05-21 | 1999-12-13 | Mcgill University | Agents interfering with the binding of protein tyrosine phosphatase pest to domains of signalling proteins as inhibitors of cell migration and/or of focal adhesion |
| US6156551A (en) * | 1998-06-05 | 2000-12-05 | Beth Israel Deaconess Medical Center | Activated mutants of SH2-domain-containing protein tyrosine phosphatases and methods of use thereof |
| US6248327B1 (en) | 1998-09-11 | 2001-06-19 | Vanderbilt University | Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis |
| US7176289B1 (en) | 1998-09-11 | 2007-02-13 | Vanderbilt University | Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis |
| US6355786B1 (en) | 1998-10-30 | 2002-03-12 | Vanderbilt University | Purified and isolated protein zero related (PZR) and therapeutic and screening methods using same |
| CA2366101A1 (en) * | 1999-03-08 | 2000-09-14 | Merck Frosst Canada & Co. | Intact cell assay for protein tyrosine phosphatases |
| US6852520B1 (en) | 1999-03-24 | 2005-02-08 | Ceptyr, Inc. | DSP-2 dual-specificity phosphatase |
| US6492157B1 (en) | 1999-04-07 | 2002-12-10 | Ceptyr, Inc. | DSP-9 dual-specificity phosphatase |
| US6841369B1 (en) | 1999-04-07 | 2005-01-11 | Ceptyr, Inc. | DSP-4 dual specificity phosphatase |
| US6551810B1 (en) | 1999-04-23 | 2003-04-22 | Ceptyr, Inc. | DSP-10 dual-specificity phosphatase |
| US6645753B1 (en) | 1999-04-27 | 2003-11-11 | Ceptyr, Inc. | DSP-5 dual-specificity phosphatase |
| CA2375145A1 (en) * | 1999-06-03 | 2000-12-14 | Cold Spring Harbor Laboratory | Substrate trapping protein tyrosine phosphatases |
| US7078210B2 (en) | 1999-07-02 | 2006-07-18 | Ceptyr, Inc. | DSP-3 dual-specificity phosphatase |
| EP1200602A1 (en) | 1999-07-20 | 2002-05-02 | Ceptyr, Inc. | Dsp-11 dual-specificity map kinase phophatase |
| WO2001057221A2 (en) | 2000-02-02 | 2001-08-09 | Ceptyr, Inc. | Dsp-12 and dsp-13 dual-specificity phosphatases |
| CA2435507A1 (en) * | 2000-02-14 | 2001-08-23 | Ceptyr, Inc. | Improved assay for protein tyrosine phosphatases |
| US6825021B2 (en) | 2000-09-19 | 2004-11-30 | Ceptyr, Inc. | DSP-15 dual-specificity phosphatase |
| US8071348B2 (en) * | 2002-01-14 | 2011-12-06 | Albert Einstein College Of Medicine Of Yeshiva University | Protein tyrosine phosphatase substrate-trapping double mutant and uses thereof |
| US20030215899A1 (en) * | 2002-02-13 | 2003-11-20 | Ceptyr, Inc. | Reversible oxidation of protein tyrosine phosphatases |
| US20030182669A1 (en) * | 2002-03-19 | 2003-09-25 | Rockman Howard A. | Phosphoinositide 3-kinase mediated inhibition of GPCRs |
| WO2003099227A2 (en) * | 2002-05-23 | 2003-12-04 | Ceptyr, Inc. | Modulation of ptp1b signal transduction by rna interference |
| US7290215B2 (en) * | 2002-06-03 | 2007-10-30 | Microsoft Corporation | Dynamic wizard interface system and method |
| EP1576139A4 (en) * | 2002-11-26 | 2007-06-20 | Cold Spring Harbor Lab | INTERACTIVE PROTEINS AND ASSOCIATED METHODS OF DEP-1 RECEPTOR PROTEIN-TYROSINE PHOSPHATASE |
| US20070238129A1 (en) * | 2006-03-29 | 2007-10-11 | Moyer Susanne C | Catalytically inactive enzymes for affinity binding |
| WO2011060076A1 (en) * | 2009-11-10 | 2011-05-19 | Amgen Inc. | Anti-c-mpl antibodies |
| CN113899902B (zh) * | 2020-06-22 | 2024-10-29 | 上海科技大学 | 一种酪氨酸磷酸酶底物鉴定方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2054602C (en) * | 1991-10-31 | 2003-04-22 | Anthony Pawson | Method for assaying for a substance that affects an sh2-phosphorylated ligand regulatory system |
| US5589375A (en) * | 1992-10-06 | 1996-12-31 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E. V. | PTP 1D: a novel protein tyrosine phosphatase |
| US5585233A (en) * | 1993-03-23 | 1996-12-17 | Max-Planck Gesellschaft Zur Forderung Der Wissenschaften E.V. | PTP-S31: A novel protein tyrosine phosphatase |
| WO1995006735A2 (en) * | 1993-09-01 | 1995-03-09 | The Ludwig Institute For Cancer Research | Nucleotide sequences for novel protein tyrosine phosphatases |
| US5744313A (en) * | 1994-12-09 | 1998-04-28 | The Regents Of The University Of California | Assay employing novel protein domain which binds tyrosine phosphorylated proteins |
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1996
- 1996-07-25 US US08/685,992 patent/US5912138A/en not_active Expired - Fee Related
-
1997
- 1997-07-24 ES ES97937017T patent/ES2281915T3/es not_active Expired - Lifetime
- 1997-07-24 AT AT97937017T patent/ATE352625T1/de not_active IP Right Cessation
- 1997-07-24 AU AU59395/98A patent/AU728405B2/en not_active Ceased
- 1997-07-24 WO PCT/US1997/013016 patent/WO1998004712A2/en not_active Ceased
- 1997-07-24 CA CA002262440A patent/CA2262440A1/en not_active Abandoned
- 1997-07-24 DE DE69737290T patent/DE69737290T2/de not_active Expired - Fee Related
- 1997-07-24 EP EP97937017A patent/EP0918867B1/en not_active Expired - Lifetime
- 1997-07-24 JP JP10508989A patent/JP2000515760A/ja active Pending
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1998
- 1998-09-01 US US09/144,925 patent/US5951979A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5951979A (en) | 1999-09-14 |
| ES2281915T3 (es) | 2007-10-01 |
| US5912138A (en) | 1999-06-15 |
| WO1998004712A2 (en) | 1998-02-05 |
| EP0918867B1 (en) | 2007-01-24 |
| EP0918867A2 (en) | 1999-06-02 |
| WO1998004712A3 (en) | 1998-03-12 |
| AU728405B2 (en) | 2001-01-11 |
| DE69737290T2 (de) | 2007-11-08 |
| AU5939598A (en) | 1999-02-16 |
| ATE352625T1 (de) | 2007-02-15 |
| DE69737290D1 (en) | 2007-03-15 |
| CA2262440A1 (en) | 1998-02-05 |
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