ES2260425T3 - Derivados de acido alcoxicarbonilamino-heteroaril-carboxilico como antagonistas ip. - Google Patents

Derivados de acido alcoxicarbonilamino-heteroaril-carboxilico como antagonistas ip.

Info

Publication number
ES2260425T3
ES2260425T3 ES02722126T ES02722126T ES2260425T3 ES 2260425 T3 ES2260425 T3 ES 2260425T3 ES 02722126 T ES02722126 T ES 02722126T ES 02722126 T ES02722126 T ES 02722126T ES 2260425 T3 ES2260425 T3 ES 2260425T3
Authority
ES
Spain
Prior art keywords
compound
phenyl
acid
group
accordance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES02722126T
Other languages
English (en)
Spanish (es)
Inventor
Francisco Javier Lopez-Tapia
Dov Nitzan
Counde O'yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2260425T3 publication Critical patent/ES2260425T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES02722126T 2001-03-02 2002-02-25 Derivados de acido alcoxicarbonilamino-heteroaril-carboxilico como antagonistas ip. Expired - Lifetime ES2260425T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27284901P 2001-03-02 2001-03-02
US272849P 2001-03-02

Publications (1)

Publication Number Publication Date
ES2260425T3 true ES2260425T3 (es) 2006-11-01

Family

ID=23041569

Family Applications (1)

Application Number Title Priority Date Filing Date
ES02722126T Expired - Lifetime ES2260425T3 (es) 2001-03-02 2002-02-25 Derivados de acido alcoxicarbonilamino-heteroaril-carboxilico como antagonistas ip.

Country Status (14)

Country Link
US (1) US6569860B2 (https=)
EP (1) EP1368345B1 (https=)
JP (1) JP2004526721A (https=)
KR (1) KR100589990B1 (https=)
CN (1) CN1280289C (https=)
AR (1) AR033429A1 (https=)
AT (1) ATE321041T1 (https=)
BR (1) BR0207730A (https=)
CA (1) CA2438813C (https=)
DE (1) DE60210058T2 (https=)
ES (1) ES2260425T3 (https=)
MX (1) MXPA03007864A (https=)
WO (1) WO2002070514A1 (https=)
ZA (1) ZA200306283B (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040054008A1 (en) 2002-09-13 2004-03-18 Tohru Araki Medicament for treatment of nocturia
JP2006517576A (ja) * 2003-02-14 2006-07-27 メディカル リサーチ カウンシル 病理的子宮症状の治療のためのｉｐレセプターアンタゴニスト
WO2007046646A1 (en) * 2005-10-20 2007-04-26 Lg Chem, Ltd. Novel organic silane compound
KR100840114B1 (ko) * 2005-10-20 2008-06-19 주식회사 엘지화학 점착제 조성물
AR069650A1 (es) * 2007-12-14 2010-02-10 Actelion Pharmaceuticals Ltd Derivados de aminopirazol como agonistas no peptidicos del receptor alx humano
US9321745B2 (en) * 2013-03-12 2016-04-26 Allergan, Inc. Inhibition of neovascularization by inhibition of prostanoid IP receptors
WO2014143591A1 (en) 2013-03-12 2014-09-18 Allergan, Inc. Inhibition of neovascularization by simultaneous inhibition of prostanoid ip and ep4 receptors
BR112020018094A2 (pt) 2018-03-08 2020-12-22 Incyte Corporation Compostos de aminopirazina diol como inibidores de pi3k-¿
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors
EP4119138A1 (en) * 2021-07-12 2023-01-18 Universität Hamburg Dhodh inhibitors and their use as antiviral agents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5908842A (en) 1995-12-08 1999-06-01 Merck & Co., Inc. Substituted 2-acylamino-pyridines as inhibitors of nitric oxide synthase
US6184242B1 (en) 1997-09-04 2001-02-06 Syntex Usa (Llc) 2-(substituted-phenyl)amino-imidazoline derivatives
WO1999026925A1 (en) * 1997-11-26 1999-06-03 Yoshitomi Pharmaceutical Industries, Ltd. Tryptase inhibitors comprising heterocyclic amide compounds
AU754253B2 (en) * 1998-10-06 2002-11-07 Dainippon Pharmaceutical Co. Ltd. 2,3-disubstituted pyridine derivatives, processes for the preparation thereof, pharmaceutical compositions containing the same and intermediates therefor
US6335459B1 (en) * 1998-12-23 2002-01-01 Syntex (U.S.A.) Llc Aryl carboxylic acid and aryl tetrazole derivatives as IP receptor modulators
KR20020060160A (ko) * 1999-08-12 2002-07-16 파마시아 이탈리아 에스.피.에이. 3(5)-아미노-피라졸 유도체, 이의 제조 방법 및항종양제로서의 이의 용도
YU68102A (sh) * 2000-03-16 2006-01-16 F. Hoffmann-La Roche Ag. Derivati karboksilne kiseline kao ip antagonisti

Also Published As

Publication number Publication date
CN1494544A (zh) 2004-05-05
JP2004526721A (ja) 2004-09-02
CA2438813C (en) 2008-07-29
AR033429A1 (es) 2003-12-17
KR20030078962A (ko) 2003-10-08
DE60210058T2 (de) 2006-11-09
CA2438813A1 (en) 2002-09-12
DE60210058D1 (de) 2006-05-11
BR0207730A (pt) 2004-03-23
US6569860B2 (en) 2003-05-27
MXPA03007864A (es) 2003-12-04
KR100589990B1 (ko) 2006-06-15
CN1280289C (zh) 2006-10-18
ATE321041T1 (de) 2006-04-15
EP1368345A1 (en) 2003-12-10
US20020169171A1 (en) 2002-11-14
EP1368345B1 (en) 2006-03-22
ZA200306283B (en) 2004-11-15
WO2002070514A1 (en) 2002-09-12

Similar Documents

Publication Publication Date Title
ES2248413T3 (es) Derivados de 2-fenilaminoimidazolin fenil cetona sustituido como antagonistas de ip.
ES2271551T3 (es) Indoles sustituidos com agonistas alfa-1.
ES2230310T3 (es) 1-aminoalquil-lactamas sustituidas y su empleo como antagonista de receptor muscarinico.
ES2250130T3 (es) Uso de antagonistas selectivos del receptor adrenergico alfa1b para el tratamiento de la disfuncion sexual.
ES2341127T3 (es) Compuestos de bencisoxazol-piperazina y procedimiento de uso.
RU2241702C2 (ru) Замещенные 1-аминоалкиллактамы, фармацевтическая композиция на их основе и способ их получения
KR20080094962A (ko) 아미드 유도체 또는 그의 염
ES2251512T3 (es) Derivados de quinazolina como antagonista adrenergicos alfa-1.
ES2260425T3 (es) Derivados de acido alcoxicarbonilamino-heteroaril-carboxilico como antagonistas ip.
ES2252443T3 (es) Derivados de acido alcoxicarbonilamino benzoico o alcoxicarbonilamino tetrazolil fenilo como antagonistas de ip.
AU2002253061A1 (en) Alkoxycarbonylamino benzoic acid or alkoxycarbonylamino tetrazolyl phenyl derivatives as IP antagonists
US6417186B1 (en) Substituted-phenyl ketone derivatives as IP antagonists
ES2313019T3 (es) Metil-indoles y metil-pirrolopiridinas como angonistas adrenergicos de alfa-1.
JP2009513521A (ja) プロスタグランジンｉ２アンタゴニストとしてのチオフェニルアミノイミダゾリン類
KR100777876B1 (ko) 프로스타글란딘 ｉ2(ｉｐ) 길항제로서 이미다졸린-2-일아미노페닐 아마이드
AU2002253060A1 (en) Alkoxycarbonylamino heteroaryl carboxylic acid derivatives as IP antagonists