JP2004526721A - Ｉｐアンタゴニストとしてのアルコキシカルボニルアミノヘテロアリールカルボン酸誘導体 - Google Patents

Ｉｐアンタゴニストとしてのアルコキシカルボニルアミノヘテロアリールカルボン酸誘導体 Download PDF

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Publication number
JP2004526721A
JP2004526721A JP2002569834A JP2002569834A JP2004526721A JP 2004526721 A JP2004526721 A JP 2004526721A JP 2002569834 A JP2002569834 A JP 2002569834A JP 2002569834 A JP2002569834 A JP 2002569834A JP 2004526721 A JP2004526721 A JP 2004526721A
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JP
Japan
Prior art keywords
group
formula
compound
phenyl
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP2002569834A
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English (en)
Japanese (ja)
Other versions
JP2004526721A5 (https=
Inventor
ロペス−タピア，フランシスコ・ハビエル
ニッツァン，ドヴ
オヤング，カウンド
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JP2004526721A publication Critical patent/JP2004526721A/ja
Publication of JP2004526721A5 publication Critical patent/JP2004526721A5/ja
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2002569834A 2001-03-02 2002-02-25 Ｉｐアンタゴニストとしてのアルコキシカルボニルアミノヘテロアリールカルボン酸誘導体 Ceased JP2004526721A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27284901P 2001-03-02 2001-03-02
PCT/EP2002/001942 WO2002070514A1 (en) 2001-03-02 2002-02-25 Alkoxycarbonylamino heteroaryl carboxylic acid derivatives as ip antagonists

Publications (2)

Publication Number Publication Date
JP2004526721A true JP2004526721A (ja) 2004-09-02
JP2004526721A5 JP2004526721A5 (https=) 2005-06-30

Family

ID=23041569

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002569834A Ceased JP2004526721A (ja) 2001-03-02 2002-02-25 Ｉｐアンタゴニストとしてのアルコキシカルボニルアミノヘテロアリールカルボン酸誘導体

Country Status (14)

Country Link
US (1) US6569860B2 (https=)
EP (1) EP1368345B1 (https=)
JP (1) JP2004526721A (https=)
KR (1) KR100589990B1 (https=)
CN (1) CN1280289C (https=)
AR (1) AR033429A1 (https=)
AT (1) ATE321041T1 (https=)
BR (1) BR0207730A (https=)
CA (1) CA2438813C (https=)
DE (1) DE60210058T2 (https=)
ES (1) ES2260425T3 (https=)
MX (1) MXPA03007864A (https=)
WO (1) WO2002070514A1 (https=)
ZA (1) ZA200306283B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011506424A (ja) * 2007-12-14 2011-03-03 アクテリオン ファーマシューティカルズ リミテッド アミノピラゾール誘導体

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040054008A1 (en) 2002-09-13 2004-03-18 Tohru Araki Medicament for treatment of nocturia
JP2006517576A (ja) * 2003-02-14 2006-07-27 メディカル リサーチ カウンシル 病理的子宮症状の治療のためのｉｐレセプターアンタゴニスト
WO2007046646A1 (en) * 2005-10-20 2007-04-26 Lg Chem, Ltd. Novel organic silane compound
KR100840114B1 (ko) * 2005-10-20 2008-06-19 주식회사 엘지화학 점착제 조성물
US9321745B2 (en) * 2013-03-12 2016-04-26 Allergan, Inc. Inhibition of neovascularization by inhibition of prostanoid IP receptors
WO2014143591A1 (en) 2013-03-12 2014-09-18 Allergan, Inc. Inhibition of neovascularization by simultaneous inhibition of prostanoid ip and ep4 receptors
BR112020018094A2 (pt) 2018-03-08 2020-12-22 Incyte Corporation Compostos de aminopirazina diol como inibidores de pi3k-¿
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors
EP4119138A1 (en) * 2021-07-12 2023-01-18 Universität Hamburg Dhodh inhibitors and their use as antiviral agents

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999026925A1 (en) * 1997-11-26 1999-06-03 Yoshitomi Pharmaceutical Industries, Ltd. Tryptase inhibitors comprising heterocyclic amide compounds
WO2000020391A1 (en) * 1998-10-06 2000-04-13 Dainippon Pharmaceutical Co., Ltd. 2,3-disubstituted pyridine derivatives, process for the preparation thereof, drug compositions containing the same and intermediates for the preparation
JP2000191523A (ja) * 1998-12-23 2000-07-11 F Hoffmann La Roche Ag アリ―ルカルボン酸及びテトラゾ―ル誘導体類
JP2003507329A (ja) * 1999-08-12 2003-02-25 フアルマシア・イタリア・エツセ・ピー・アー ３（５）−アミノ−ピラゾール誘導体、それらの製造方法および抗腫瘍薬としてのそれらの使用
JP2003527368A (ja) * 2000-03-16 2003-09-16 エフ．ホフマン−ラ ロシュ アーゲー Ｉｐアンタゴニストとしてのカルボン酸誘導体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5908842A (en) 1995-12-08 1999-06-01 Merck & Co., Inc. Substituted 2-acylamino-pyridines as inhibitors of nitric oxide synthase
US6184242B1 (en) 1997-09-04 2001-02-06 Syntex Usa (Llc) 2-(substituted-phenyl)amino-imidazoline derivatives

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999026925A1 (en) * 1997-11-26 1999-06-03 Yoshitomi Pharmaceutical Industries, Ltd. Tryptase inhibitors comprising heterocyclic amide compounds
WO2000020391A1 (en) * 1998-10-06 2000-04-13 Dainippon Pharmaceutical Co., Ltd. 2,3-disubstituted pyridine derivatives, process for the preparation thereof, drug compositions containing the same and intermediates for the preparation
JP2000191523A (ja) * 1998-12-23 2000-07-11 F Hoffmann La Roche Ag アリ―ルカルボン酸及びテトラゾ―ル誘導体類
JP2003507329A (ja) * 1999-08-12 2003-02-25 フアルマシア・イタリア・エツセ・ピー・アー ３（５）−アミノ−ピラゾール誘導体、それらの製造方法および抗腫瘍薬としてのそれらの使用
JP2003527368A (ja) * 2000-03-16 2003-09-16 エフ．ホフマン−ラ ロシュ アーゲー Ｉｐアンタゴニストとしてのカルボン酸誘導体

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011506424A (ja) * 2007-12-14 2011-03-03 アクテリオン ファーマシューティカルズ リミテッド アミノピラゾール誘導体

Also Published As

Publication number Publication date
CN1494544A (zh) 2004-05-05
CA2438813C (en) 2008-07-29
AR033429A1 (es) 2003-12-17
KR20030078962A (ko) 2003-10-08
DE60210058T2 (de) 2006-11-09
CA2438813A1 (en) 2002-09-12
DE60210058D1 (de) 2006-05-11
BR0207730A (pt) 2004-03-23
US6569860B2 (en) 2003-05-27
MXPA03007864A (es) 2003-12-04
KR100589990B1 (ko) 2006-06-15
CN1280289C (zh) 2006-10-18
ES2260425T3 (es) 2006-11-01
ATE321041T1 (de) 2006-04-15
EP1368345A1 (en) 2003-12-10
US20020169171A1 (en) 2002-11-14
EP1368345B1 (en) 2006-03-22
ZA200306283B (en) 2004-11-15
WO2002070514A1 (en) 2002-09-12

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