ES2213228T3 - Nuevas imidazo- y oxazolo-piridinas como agentes inhibidores de fosfodiesterasas. - Google Patents

Nuevas imidazo- y oxazolo-piridinas como agentes inhibidores de fosfodiesterasas.

Info

Publication number
ES2213228T3
ES2213228T3 ES97950116T ES97950116T ES2213228T3 ES 2213228 T3 ES2213228 T3 ES 2213228T3 ES 97950116 T ES97950116 T ES 97950116T ES 97950116 T ES97950116 T ES 97950116T ES 2213228 T3 ES2213228 T3 ES 2213228T3
Authority
ES
Spain
Prior art keywords
alkyl
compounds
alkoxy
formula
methoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97950116T
Other languages
English (en)
Spanish (es)
Inventor
Hermann Amschler
Thomas Martin
Dieter Flockerzi
Beate Schmidt
Ulrich Thibaut
Armin Hatzelmann
Hildegard Boss
Dietrich Hafner
Hans-Peter Kley
Rolf Beume
Thomas Bar
Wolf-Rudiger Ulrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Altana Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma AG filed Critical Altana Pharma AG
Application granted granted Critical
Publication of ES2213228T3 publication Critical patent/ES2213228T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES97950116T 1996-11-11 1997-11-05 Nuevas imidazo- y oxazolo-piridinas como agentes inhibidores de fosfodiesterasas. Expired - Lifetime ES2213228T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19646460 1996-11-11
DE19646460 1996-11-11
EP96118187 1996-11-13
EP96118187 1996-11-13

Publications (1)

Publication Number Publication Date
ES2213228T3 true ES2213228T3 (es) 2004-08-16

Family

ID=26031166

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97950116T Expired - Lifetime ES2213228T3 (es) 1996-11-11 1997-11-05 Nuevas imidazo- y oxazolo-piridinas como agentes inhibidores de fosfodiesterasas.

Country Status (12)

Country Link
US (2) US6172074B1 (de)
EP (1) EP0937075B1 (de)
JP (1) JP2001503443A (de)
AT (1) ATE256683T1 (de)
AU (1) AU5318698A (de)
CY (1) CY2582B2 (de)
DE (1) DE59711147D1 (de)
DK (1) DK0937075T3 (de)
ES (1) ES2213228T3 (de)
PT (1) PT937075E (de)
SI (1) SI0937075T1 (de)
WO (1) WO1998021209A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1075476T1 (en) 1998-05-05 2003-10-31 Altana Pharma Ag Novel benzimidazoles and benzoxazoles
GB9828340D0 (en) * 1998-12-22 1999-02-17 Novartis Ag Organic compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR208500A1 (es) * 1972-06-14 1977-02-15 Merck & Co Inc Procedimiento para la preparacion de derivados de oxazolo(4,5-b)-piridinas
US4038396A (en) * 1975-02-24 1977-07-26 Merck & Co., Inc. Anti-inflammatory oxazole[4,5-b]pyridines
DE2527321A1 (de) * 1975-06-19 1976-12-23 Merck & Co Inc Oxazol eckige klammer auf 4,5-b eckige klammer zu pyridine
US4011326A (en) * 1975-07-29 1977-03-08 Merck & Co., Inc. 2-Substituted oxazolo[4,5-b]pyridine anti-inflammatory agents
DE2619547A1 (de) * 1976-05-04 1977-11-24 Dynamit Nobel Ag Verfahren zur herstellung von 2-aryl- benzoxazolen und 2-aryl-benzthiazolen
ES517193A0 (es) * 1981-11-10 1983-12-01 Wellcome Found Un procedimiento para la preparacion de nuevos derivados de imidazo (4,5-c)piridina.
ES2192192T3 (es) * 1992-12-02 2003-10-01 Pfizer Dieteres de catecol como inhibidores selectivos de pde iv.
PT730587E (pt) * 1993-11-26 2000-05-31 Pfizer 3-aril-2-isoxazolinas como agentes anti-inflamatorios
GB9412383D0 (en) * 1994-06-21 1994-08-10 Celltech Ltd Chemical compound
PL319605A1 (en) * 1994-10-12 1997-08-18 Euro Celtique Sa Novel benzoxazoles
ATE178776T1 (de) * 1994-10-20 1999-04-15 Procter & Gamble Verfahren zum verbinden von absorbierenden artikeln durch löten

Also Published As

Publication number Publication date
JP2001503443A (ja) 2001-03-13
AU5318698A (en) 1998-06-03
DK0937075T3 (da) 2004-04-13
EP0937075B1 (de) 2003-12-17
ATE256683T1 (de) 2004-01-15
EP0937075A1 (de) 1999-08-25
WO1998021209A1 (de) 1998-05-22
SI0937075T1 (en) 2004-06-30
CY2582B2 (en) 2009-11-04
US6306867B1 (en) 2001-10-23
US6172074B1 (en) 2001-01-09
DE59711147D1 (de) 2004-01-29
PT937075E (pt) 2004-05-31

Similar Documents

Publication Publication Date Title
ES2286491T3 (es) Piperidina-ftalazonas sustituidas con pirrolidinadiona, como agentes inhibidores de la pde4.
ES2188983T4 (es) Nuevas benzofuran-4-carboxamidas.
RU2137754C1 (ru) Фторалкоксизамещенные бензамиды, способ их получения и фармацевтическая композиция на их основе
ES2274913T3 (es) Aza y poliaza-naftalenil carboxamidas utiles como inhibidores de vih integrada.
ES2217575T3 (es) Nuevos derivados de tetrazol.
ES2208950T3 (es) Nuevos derivados de tiazol con un efecto inhibidor de fosfodiesterasas.
US5902824A (en) Phenyldihydrobenzofuranes
JP4223075B2 (ja) 気管支治療薬としてのベンゾナフチリジン
ES2224745T3 (es) N-oxidos de benzonaftiridina con actividad inhibidora de pde3 y pde4.
EP1699781A1 (de) Für die behandlung von atemwegserkrankungen geeignete 1-essigsäure-indol-, -indazol- und -benzimidazolderivate
CA2330738A1 (en) Novel n-oxides of benzonaphthyridines
CA2674647A1 (en) Chemical compounds 637
ES2206909T3 (es) Derivados de tetrazol.
ES2205833T3 (es) Benzamidas con sustituyentes tetrahidrofuraniloxi con inhibidores de la fosfodiesterasa 4.
ES2242594T3 (es) N-oxidos de fenantridinas con una acitvidad inhidora de pde-iv.
ES2241571T3 (es) N-oxidos de fenantrinida con actividad inhividora de pde-iv.
ES2216349T3 (es) Dihidrobenzofuranos.
US6043263A (en) (2,3-dihydrobenzofuranyl)-thiazoles as phosphodiesterase inhibitors
ES2255483T3 (es) 6-arilfenantridinas con actividad inhibidora de pde-iv.
ES2219031T3 (es) Nuevos benzoxazoles con actividad inhibidora de pde.
ES2236288T3 (es) 6-heteroarilfenantridinas.
ES2236504T3 (es) 6-fenilbenzonaftiridinas.
JP2001510826A (ja) 置換６−アルキルフェナントリジン
AU781503B2 (en) Phthalazinone derivatives as PDE 4 inhibitors
ES2213228T3 (es) Nuevas imidazo- y oxazolo-piridinas como agentes inhibidores de fosfodiesterasas.