ES2206438T3 - Derivados de isoindolo-indolona, su procedimiento de preparaacion y las composiciones farmaceuticas que los contienen. - Google Patents

Derivados de isoindolo-indolona, su procedimiento de preparaacion y las composiciones farmaceuticas que los contienen.

Info

Publication number
ES2206438T3
ES2206438T3 ES02290598T ES02290598T ES2206438T3 ES 2206438 T3 ES2206438 T3 ES 2206438T3 ES 02290598 T ES02290598 T ES 02290598T ES 02290598 T ES02290598 T ES 02290598T ES 2206438 T3 ES2206438 T3 ES 2206438T3
Authority
ES
Spain
Prior art keywords
branched
linear
formula
compound
oxyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES02290598T
Other languages
English (en)
Spanish (es)
Inventor
Michel Wierzbicki
Marie-Francoise Boussard
Anne Rousseau
Jean-Albert Boutin
Philippe Delagrange
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Les Laboratoires Servier SAS
Original Assignee
Les Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Les Laboratoires Servier SAS filed Critical Les Laboratoires Servier SAS
Application granted granted Critical
Publication of ES2206438T3 publication Critical patent/ES2206438T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES02290598T 2001-03-12 2002-03-11 Derivados de isoindolo-indolona, su procedimiento de preparaacion y las composiciones farmaceuticas que los contienen. Expired - Lifetime ES2206438T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0103293 2001-03-12
FR0103293A FR2821843B1 (fr) 2001-03-12 2001-03-12 Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ES2206438T3 true ES2206438T3 (es) 2004-05-16

Family

ID=8860976

Family Applications (1)

Application Number Title Priority Date Filing Date
ES02290598T Expired - Lifetime ES2206438T3 (es) 2001-03-12 2002-03-11 Derivados de isoindolo-indolona, su procedimiento de preparaacion y las composiciones farmaceuticas que los contienen.

Country Status (24)

Country Link
US (1) US6465660B1 (enExample)
EP (1) EP1241169B1 (enExample)
JP (1) JP3842151B2 (enExample)
KR (1) KR100450313B1 (enExample)
CN (1) CN1159316C (enExample)
AR (1) AR034583A1 (enExample)
AT (1) ATE248171T1 (enExample)
AU (1) AU779702B2 (enExample)
BR (1) BR0200721A (enExample)
CA (1) CA2376876C (enExample)
DE (1) DE60200023T2 (enExample)
DK (1) DK1241169T3 (enExample)
EA (1) EA004035B1 (enExample)
ES (1) ES2206438T3 (enExample)
FR (1) FR2821843B1 (enExample)
HK (1) HK1049000B (enExample)
HU (1) HUP0200913A3 (enExample)
MX (1) MXPA02002601A (enExample)
NO (1) NO20021198L (enExample)
NZ (1) NZ517742A (enExample)
PL (1) PL352750A1 (enExample)
PT (1) PT1241169E (enExample)
SI (1) SI1241169T1 (enExample)
ZA (1) ZA200202030B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2826009B1 (fr) * 2001-06-13 2003-08-15 Servier Lab Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
RU2320663C2 (ru) * 2002-06-21 2008-03-27 Сувен Лайф Сайенсиз Лимитед Новые арилалкилиндолы с аффинностью к серотониновым рецепторам, пригодные в качестве лекарственных средств, способ их получения и содержащие их фармацевтические композиции
JP4460446B2 (ja) * 2002-06-21 2010-05-12 スベン ライフ サイエンシズ リミティド 治療薬剤として有用なセロトニン受容体親和性を有する新規の四環系アリールカルボニル・インドール、その製造方法、並びにそれらを含む医薬組成物
PT1567492E (pt) * 2002-11-28 2013-07-22 Suven Life Sciences Ltd N-arilsulfonil-3-aminoalcoxi-indóis
SI1581538T1 (sl) * 2002-12-18 2007-08-31 Suven Life Sciences Ltd Tetraciklični 3-substituirani indoli z afiniteto za receptor serotonina
RU2387655C2 (ru) * 2004-08-09 2010-04-27 Бристол-Маерс Сквибб Компани Ингибиторы репликации вируса гепатита с
ES2580702B1 (es) 2015-02-25 2017-06-08 Palobiofarma, S.L. Derivados de 2-aminopiridina como antagonistas del receptor A2b de adenosina y ligandos del receptor MT3 de melatonina
WO2024050126A2 (en) 2022-09-02 2024-03-07 Dexcom, Inc. Continuous analyte sensor devices and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5377098A (en) * 1976-12-16 1978-07-08 Sumitomo Chem Co Ltd Preparation of indoloisoquinoline derivative
US4452808A (en) * 1982-12-07 1984-06-05 Smithkline Beckman Corporation 4-Aminoalkyl-2(3H)-indolones
US5441955A (en) * 1993-11-19 1995-08-15 Pathogenesis Corporation Indolo[2,1-biquinazoline-6,12-dione antibacterial compounds and methods of use thereof
FR2743365A1 (fr) * 1996-01-10 1997-07-11 Rhone Poulenc Rorer Sa Derives de 5h,10h-imidazo(1,2-a)indolo(3,2-e)pyrazine-4-one, leur preparation et les medicaments les contenant
WO2002000215A1 (en) * 2000-06-23 2002-01-03 Cognetix, Inc. Subtype selective melatonergics

Also Published As

Publication number Publication date
JP3842151B2 (ja) 2006-11-08
AR034583A1 (es) 2004-03-03
SI1241169T1 (en) 2003-12-31
NZ517742A (en) 2003-02-28
ZA200202030B (en) 2002-10-03
NO20021198L (no) 2002-09-13
BR0200721A (pt) 2002-12-03
EP1241169A1 (fr) 2002-09-18
EA200200241A1 (ru) 2002-10-31
MXPA02002601A (es) 2004-11-12
EA004035B1 (ru) 2003-12-25
HUP0200913A3 (en) 2004-11-29
HK1049000A1 (en) 2003-04-25
AU2324202A (en) 2002-09-19
PL352750A1 (en) 2002-09-23
FR2821843B1 (fr) 2003-05-09
PT1241169E (pt) 2003-11-28
DE60200023D1 (de) 2003-10-02
US6465660B1 (en) 2002-10-15
CA2376876A1 (fr) 2002-09-12
HUP0200913A2 (hu) 2002-11-28
AU779702B2 (en) 2005-02-10
HK1049000B (zh) 2005-01-07
EP1241169B1 (fr) 2003-08-27
FR2821843A1 (fr) 2002-09-13
CN1159316C (zh) 2004-07-28
NO20021198D0 (no) 2002-03-11
CA2376876C (fr) 2006-07-11
CN1375494A (zh) 2002-10-23
HU0200913D0 (enExample) 2002-05-29
JP2002265469A (ja) 2002-09-18
ATE248171T1 (de) 2003-09-15
DK1241169T3 (da) 2003-11-24
KR100450313B1 (ko) 2004-09-30
KR20020072782A (ko) 2002-09-18
DE60200023T2 (de) 2004-06-03

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