BR0200721A - Compostos de isoindoloindolona, processo para a fabricação dos mesmos e composições farmacêuticas que contêm os mesmos - Google Patents
Compostos de isoindoloindolona, processo para a fabricação dos mesmos e composições farmacêuticas que contêm os mesmosInfo
- Publication number
- BR0200721A BR0200721A BR0200721-5A BR0200721A BR0200721A BR 0200721 A BR0200721 A BR 0200721A BR 0200721 A BR0200721 A BR 0200721A BR 0200721 A BR0200721 A BR 0200721A
- Authority
- BR
- Brazil
- Prior art keywords
- same
- isoindoloindolone
- compounds
- manufacture
- pharmaceutical compositions
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- UNRFFBAJODEDDJ-UHFFFAOYSA-N C1=CC2=C3NC=CC3=CC=C2C2=C1C(=O)N=C2 Chemical class C1=CC2=C3NC=CC3=CC=C2C2=C1C(=O)N=C2 UNRFFBAJODEDDJ-UHFFFAOYSA-N 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 125000002102 aryl alkyloxo group Chemical group 0.000 abstract 2
- 125000005199 aryl carbonyloxy group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 2
- OEJVZIVVOMBRNM-UHFFFAOYSA-N 1,3-dimethoxy-5H-isoindole Chemical compound COC1=NC(=C2C=CCC=C12)OC OEJVZIVVOMBRNM-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000005129 aryl carbonyl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Child & Adolescent Psychology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0103293A FR2821843B1 (fr) | 2001-03-12 | 2001-03-12 | Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0200721A true BR0200721A (pt) | 2002-12-03 |
Family
ID=8860976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0200721-5A BR0200721A (pt) | 2001-03-12 | 2002-03-11 | Compostos de isoindoloindolona, processo para a fabricação dos mesmos e composições farmacêuticas que contêm os mesmos |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6465660B1 (enExample) |
| EP (1) | EP1241169B1 (enExample) |
| JP (1) | JP3842151B2 (enExample) |
| KR (1) | KR100450313B1 (enExample) |
| CN (1) | CN1159316C (enExample) |
| AR (1) | AR034583A1 (enExample) |
| AT (1) | ATE248171T1 (enExample) |
| AU (1) | AU779702B2 (enExample) |
| BR (1) | BR0200721A (enExample) |
| CA (1) | CA2376876C (enExample) |
| DE (1) | DE60200023T2 (enExample) |
| DK (1) | DK1241169T3 (enExample) |
| EA (1) | EA004035B1 (enExample) |
| ES (1) | ES2206438T3 (enExample) |
| FR (1) | FR2821843B1 (enExample) |
| HK (1) | HK1049000B (enExample) |
| HU (1) | HUP0200913A3 (enExample) |
| MX (1) | MXPA02002601A (enExample) |
| NO (1) | NO20021198L (enExample) |
| NZ (1) | NZ517742A (enExample) |
| PL (1) | PL352750A1 (enExample) |
| PT (1) | PT1241169E (enExample) |
| SI (1) | SI1241169T1 (enExample) |
| ZA (1) | ZA200202030B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2826009B1 (fr) * | 2001-06-13 | 2003-08-15 | Servier Lab | Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| SI1517909T1 (sl) * | 2002-06-21 | 2007-06-30 | Suven Life Sciences Ltd | Novi tetraciklični arilkarbonil indoli, ki imajo afiniteto za serotoninski receptor, uporabni kot terapevtska sredstva, postopek za njihovo pripravo in farmacevtski sestavki, ki jih vsebujejo |
| BR0312175A (pt) * | 2002-06-21 | 2005-04-05 | Suven Life Sciences Ltd | Composto, composição farmacêutica, uso de um composto, método para o tratamento e método para reduzir a morbidez e a mortalidade associadas com o excesso de peso |
| US7507835B2 (en) * | 2002-11-28 | 2009-03-24 | Suven Life Sciences Ltd. | N-arylsulfonyl-3-aminoalkoxyindoles |
| JP4571507B2 (ja) * | 2002-12-18 | 2010-10-27 | スベン ライフ サイエンシズ リミティド | セロトニン受容体親和性を有する四環系３−置換インドール |
| RU2387655C2 (ru) * | 2004-08-09 | 2010-04-27 | Бристол-Маерс Сквибб Компани | Ингибиторы репликации вируса гепатита с |
| ES2580702B1 (es) | 2015-02-25 | 2017-06-08 | Palobiofarma, S.L. | Derivados de 2-aminopiridina como antagonistas del receptor A2b de adenosina y ligandos del receptor MT3 de melatonina |
| AU2023333524A1 (en) | 2022-09-02 | 2025-04-03 | Dexcom, Inc. | Continuous analyte sensor devices and methods |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5377098A (en) * | 1976-12-16 | 1978-07-08 | Sumitomo Chem Co Ltd | Preparation of indoloisoquinoline derivative |
| US4452808A (en) * | 1982-12-07 | 1984-06-05 | Smithkline Beckman Corporation | 4-Aminoalkyl-2(3H)-indolones |
| US5441955A (en) * | 1993-11-19 | 1995-08-15 | Pathogenesis Corporation | Indolo[2,1-biquinazoline-6,12-dione antibacterial compounds and methods of use thereof |
| FR2743365A1 (fr) * | 1996-01-10 | 1997-07-11 | Rhone Poulenc Rorer Sa | Derives de 5h,10h-imidazo(1,2-a)indolo(3,2-e)pyrazine-4-one, leur preparation et les medicaments les contenant |
| US20020040018A1 (en) * | 2000-06-23 | 2002-04-04 | Jones Robert M. | Subtype selective melatonergics |
-
2001
- 2001-03-12 FR FR0103293A patent/FR2821843B1/fr not_active Expired - Fee Related
-
2002
- 2002-02-26 US US10/083,074 patent/US6465660B1/en not_active Expired - Fee Related
- 2002-03-09 KR KR10-2002-0012699A patent/KR100450313B1/ko not_active Expired - Fee Related
- 2002-03-11 ES ES02290598T patent/ES2206438T3/es not_active Expired - Lifetime
- 2002-03-11 PT PT02290598T patent/PT1241169E/pt unknown
- 2002-03-11 NO NO20021198A patent/NO20021198L/no not_active Application Discontinuation
- 2002-03-11 BR BR0200721-5A patent/BR0200721A/pt not_active IP Right Cessation
- 2002-03-11 NZ NZ517742A patent/NZ517742A/xx unknown
- 2002-03-11 AT AT02290598T patent/ATE248171T1/de not_active IP Right Cessation
- 2002-03-11 CA CA002376876A patent/CA2376876C/fr not_active Expired - Fee Related
- 2002-03-11 EP EP02290598A patent/EP1241169B1/fr not_active Expired - Lifetime
- 2002-03-11 DE DE60200023T patent/DE60200023T2/de not_active Expired - Fee Related
- 2002-03-11 EA EA200200241A patent/EA004035B1/ru unknown
- 2002-03-11 AR ARP020100863A patent/AR034583A1/es active IP Right Grant
- 2002-03-11 JP JP2002065233A patent/JP3842151B2/ja not_active Expired - Fee Related
- 2002-03-11 SI SI200230002T patent/SI1241169T1/xx unknown
- 2002-03-11 MX MXPA02002601A patent/MXPA02002601A/es active IP Right Grant
- 2002-03-11 DK DK02290598T patent/DK1241169T3/da active
- 2002-03-11 HU HU0200913A patent/HUP0200913A3/hu unknown
- 2002-03-12 ZA ZA200202030A patent/ZA200202030B/xx unknown
- 2002-03-12 PL PL02352750A patent/PL352750A1/xx not_active Application Discontinuation
- 2002-03-12 AU AU23242/02A patent/AU779702B2/en not_active Ceased
- 2002-03-12 CN CNB021070547A patent/CN1159316C/zh not_active Expired - Fee Related
-
2003
- 2003-02-18 HK HK03101182.3A patent/HK1049000B/zh not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9915967A (pt) | Derivados de propanolamina substituìdos por arila, proceso para sua preparação, medicamentos contendo estes compostos e seu uso | |
| BR0214469A (pt) | 17alfa-alquil-17beta-óxi-estratrienos e produtos intermediários para sua preparação, aplicação dos 17alfa-alquil-17beta-óxi-estratrienos para a preparação de medicamentos bem como preparações farmacêuticas | |
| BRPI0112986B8 (pt) | compostos azabicíclicos, processo para a sua preparação, bem como composições farmacêuticas compreendendo os ditos compostos | |
| BR0003105A (pt) | Compostos de beta-carbolina, processo para sua preparação e composições farmacêuticas contendo os mesmos | |
| BRPI0110955B8 (pt) | derivados de tropano composição farmacêutica, uso dos mesmos na fabricação de um medicamento bem como processo para a preparação dos mesmos. | |
| BR9814018A (pt) | Derivados de tienopirimidina e tienopiridina úteis como agentes anticâncer | |
| ES2081187T3 (es) | Nuevas naftil-alquil-aminas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen. | |
| BR0011738A (pt) | Derivados de benzeno, processo para a preparação dos mesmos e composições farmacêuticas que os contêm | |
| BR9802804A (pt) | Compostos benzimidazol, benzoxazol e benzotiazol, processo para sua preparação e composições farmacéuticas contendo os mesmos. | |
| BR9911274A (pt) | Derivados da artemisinina, seus processos de preparação e as composições farmacêuticas que os contêm | |
| BR0016130A (pt) | Composto, formulação farmacêutica, e, uso de um composto | |
| BRPI0012475A (pt) | composto derivado de titânio, seu processo de preparação e utilização, bem como composição para uso oral compreendendo o mesmo. | |
| BR0100234A (pt) | Compostos de piperidina-4-sulfonamida, processo para a sua preparação e composições farmacêuticas contendo os mesmos | |
| BR0104471A (pt) | Compostos de ciclobutenodiona, um processo para a preparação dos mesmos e composições farmacêuticas que contêm os mesmos | |
| BR0106248A (pt) | Inibidores de metaloprotease, processo para a sua preparação e composições farmacêuticas contendo os mesmos | |
| BR9800763A (pt) | Novos compostos 2-amino indano, um processo para sua preparação e composições farmacêuticas contendo os mesmos. | |
| PT937043E (pt) | Novos derivados tetra-hidropiridinicos substituidos processo para a sua preparacao e as composicoes farmaceuticas que os contem | |
| BR0300698A (pt) | Compostos derivados de quinazolina, um processo para sua preparação e composições farmacêuticas contendo-os | |
| EA200200241A1 (ru) | Новые производные изоиндолоиндолона, способ их получения и содержащие их фармацевтические композиции | |
| BR9804485A (pt) | Compostos de indanol, processo para sua preparação e composições farmacêuticas contendo os mesmos. | |
| ES2077473T3 (es) | Nuevos compuestos tiocromanicos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. | |
| BR0215145A (pt) | Compostos de benzotiazina e de benzotiadiazina, um processo para a preparação dos mesmos e composições farmacêuticas que contêm os mesmos | |
| BR0008511A (pt) | Sistemas tiazol policìclicos e seu emprego como anoréticos contendo estes compostos | |
| EA200200263A2 (ru) | Новые производные инденоиндолона, способ их получения и содержащие их фармацевтические композиции | |
| BR9705448A (pt) | Compostos substituìdos de 7,12-dioxabenz [a] antraceno, processo para sua preparação e composições farmacêuticas que os contêm. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A ANUI DADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2103 DE 26/04/2011. |