CA2376876C - Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent - Google Patents
Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent Download PDFInfo
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- CA2376876C CA2376876C CA002376876A CA2376876A CA2376876C CA 2376876 C CA2376876 C CA 2376876C CA 002376876 A CA002376876 A CA 002376876A CA 2376876 A CA2376876 A CA 2376876A CA 2376876 C CA2376876 C CA 2376876C
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- hydroxy
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- 150000001875 compounds Chemical class 0.000 title claims abstract description 47
- 238000004519 manufacturing process Methods 0.000 title claims description 4
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- 238000011282 treatment Methods 0.000 claims abstract description 14
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- 125000004423 acyloxy group Chemical group 0.000 claims abstract description 9
- 125000005199 aryl carbonyloxy group Chemical group 0.000 claims abstract description 9
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- 125000003710 aryl alkyl group Chemical group 0.000 claims abstract description 3
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- IRPIYZBBHNVOHO-UHFFFAOYSA-N 2-hydroxy-8,9-dimethoxyisoindolo[2,3-a]indol-6-one Chemical compound OC1=CC=C2N3C(=O)C(C=C(C(=C4)OC)OC)=C4C3=CC2=C1 IRPIYZBBHNVOHO-UHFFFAOYSA-N 0.000 claims description 2
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- BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical compound NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 description 1
- CRNIEXJWYHGTGR-UHFFFAOYSA-N 3-bromo-5,6-dimethoxy-3h-2-benzofuran-1-one Chemical compound C1=C(OC)C(OC)=CC2=C1C(=O)OC2Br CRNIEXJWYHGTGR-UHFFFAOYSA-N 0.000 description 1
- KGXOQXGHUJDCCU-UHFFFAOYSA-N 4,6-dimethyl-3-oxo-1h-2-benzofuran-5-carboxylic acid Chemical compound CC1=C(C(O)=O)C(C)=CC2=C1C(=O)OC2 KGXOQXGHUJDCCU-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0103293A FR2821843B1 (fr) | 2001-03-12 | 2001-03-12 | Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR01.03293 | 2001-03-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2376876A1 CA2376876A1 (fr) | 2002-09-12 |
| CA2376876C true CA2376876C (fr) | 2006-07-11 |
Family
ID=8860976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002376876A Expired - Fee Related CA2376876C (fr) | 2001-03-12 | 2002-03-11 | Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6465660B1 (enExample) |
| EP (1) | EP1241169B1 (enExample) |
| JP (1) | JP3842151B2 (enExample) |
| KR (1) | KR100450313B1 (enExample) |
| CN (1) | CN1159316C (enExample) |
| AR (1) | AR034583A1 (enExample) |
| AT (1) | ATE248171T1 (enExample) |
| AU (1) | AU779702B2 (enExample) |
| BR (1) | BR0200721A (enExample) |
| CA (1) | CA2376876C (enExample) |
| DE (1) | DE60200023T2 (enExample) |
| DK (1) | DK1241169T3 (enExample) |
| EA (1) | EA004035B1 (enExample) |
| ES (1) | ES2206438T3 (enExample) |
| FR (1) | FR2821843B1 (enExample) |
| HK (1) | HK1049000B (enExample) |
| HU (1) | HUP0200913A3 (enExample) |
| MX (1) | MXPA02002601A (enExample) |
| NO (1) | NO20021198L (enExample) |
| NZ (1) | NZ517742A (enExample) |
| PL (1) | PL352750A1 (enExample) |
| PT (1) | PT1241169E (enExample) |
| SI (1) | SI1241169T1 (enExample) |
| ZA (1) | ZA200202030B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2826009B1 (fr) * | 2001-06-13 | 2003-08-15 | Servier Lab | Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| EP1537113B9 (en) * | 2002-06-21 | 2010-05-26 | Suven Life Sciences Limited | Arylalkyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them |
| CA2490002C (en) * | 2002-06-21 | 2009-07-07 | Suven Life Sciences Limited | Novel tetracyclic arylcarbonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them |
| ES2425143T3 (es) * | 2002-11-28 | 2013-10-11 | Suven Life Sciences Limited | N-Arilsulfonil-3-aminoalcoxiindoles |
| KR100739987B1 (ko) * | 2002-12-18 | 2007-07-16 | 수벤 라이프 사이언시스 리미티드 | 세로토닌 수용체 친화력을 가지는 테트라사이클릭 3-치환인돌 |
| RU2387655C2 (ru) * | 2004-08-09 | 2010-04-27 | Бристол-Маерс Сквибб Компани | Ингибиторы репликации вируса гепатита с |
| ES2580702B1 (es) | 2015-02-25 | 2017-06-08 | Palobiofarma, S.L. | Derivados de 2-aminopiridina como antagonistas del receptor A2b de adenosina y ligandos del receptor MT3 de melatonina |
| JP2025530666A (ja) | 2022-09-02 | 2025-09-17 | デックスコム・インコーポレーテッド | 連続分析物センサデバイス及び方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5377098A (en) * | 1976-12-16 | 1978-07-08 | Sumitomo Chem Co Ltd | Preparation of indoloisoquinoline derivative |
| US4452808A (en) * | 1982-12-07 | 1984-06-05 | Smithkline Beckman Corporation | 4-Aminoalkyl-2(3H)-indolones |
| US5441955A (en) * | 1993-11-19 | 1995-08-15 | Pathogenesis Corporation | Indolo[2,1-biquinazoline-6,12-dione antibacterial compounds and methods of use thereof |
| FR2743365A1 (fr) * | 1996-01-10 | 1997-07-11 | Rhone Poulenc Rorer Sa | Derives de 5h,10h-imidazo(1,2-a)indolo(3,2-e)pyrazine-4-one, leur preparation et les medicaments les contenant |
| US20020040018A1 (en) * | 2000-06-23 | 2002-04-04 | Jones Robert M. | Subtype selective melatonergics |
-
2001
- 2001-03-12 FR FR0103293A patent/FR2821843B1/fr not_active Expired - Fee Related
-
2002
- 2002-02-26 US US10/083,074 patent/US6465660B1/en not_active Expired - Fee Related
- 2002-03-09 KR KR10-2002-0012699A patent/KR100450313B1/ko not_active Expired - Fee Related
- 2002-03-11 CA CA002376876A patent/CA2376876C/fr not_active Expired - Fee Related
- 2002-03-11 PT PT02290598T patent/PT1241169E/pt unknown
- 2002-03-11 NZ NZ517742A patent/NZ517742A/xx unknown
- 2002-03-11 ES ES02290598T patent/ES2206438T3/es not_active Expired - Lifetime
- 2002-03-11 NO NO20021198A patent/NO20021198L/no not_active Application Discontinuation
- 2002-03-11 EA EA200200241A patent/EA004035B1/ru unknown
- 2002-03-11 JP JP2002065233A patent/JP3842151B2/ja not_active Expired - Fee Related
- 2002-03-11 AR ARP020100863A patent/AR034583A1/es active IP Right Grant
- 2002-03-11 SI SI200230002T patent/SI1241169T1/xx unknown
- 2002-03-11 AT AT02290598T patent/ATE248171T1/de not_active IP Right Cessation
- 2002-03-11 MX MXPA02002601A patent/MXPA02002601A/es active IP Right Grant
- 2002-03-11 HU HU0200913A patent/HUP0200913A3/hu unknown
- 2002-03-11 DE DE60200023T patent/DE60200023T2/de not_active Expired - Fee Related
- 2002-03-11 BR BR0200721-5A patent/BR0200721A/pt not_active IP Right Cessation
- 2002-03-11 DK DK02290598T patent/DK1241169T3/da active
- 2002-03-11 EP EP02290598A patent/EP1241169B1/fr not_active Expired - Lifetime
- 2002-03-12 CN CNB021070547A patent/CN1159316C/zh not_active Expired - Fee Related
- 2002-03-12 AU AU23242/02A patent/AU779702B2/en not_active Ceased
- 2002-03-12 PL PL02352750A patent/PL352750A1/xx not_active Application Discontinuation
- 2002-03-12 ZA ZA200202030A patent/ZA200202030B/xx unknown
-
2003
- 2003-02-18 HK HK03101182.3A patent/HK1049000B/zh not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |