ZA200202030B - Isoindoloindolone compounds, a process for their preparation and pharmaceutical compositions containing them. - Google Patents

Isoindoloindolone compounds, a process for their preparation and pharmaceutical compositions containing them.

Info

Publication number
ZA200202030B
ZA200202030B ZA200202030A ZA200202030A ZA200202030B ZA 200202030 B ZA200202030 B ZA 200202030B ZA 200202030 A ZA200202030 A ZA 200202030A ZA 200202030 A ZA200202030 A ZA 200202030A ZA 200202030 B ZA200202030 B ZA 200202030B
Authority
ZA
South Africa
Prior art keywords
isoindoloindolone
compounds
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
ZA200202030A
Other languages
English (en)
Inventor
Michel Wierzbicki
Marie-Francoise Boussard
Anne Rousseau
Jean Albert Boutin
Philippe Delagrange
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of ZA200202030B publication Critical patent/ZA200202030B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA200202030A 2001-03-12 2002-03-12 Isoindoloindolone compounds, a process for their preparation and pharmaceutical compositions containing them. ZA200202030B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0103293A FR2821843B1 (fr) 2001-03-12 2001-03-12 Nouveaux derives d'isoindoloindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA200202030B true ZA200202030B (en) 2002-10-03

Family

ID=8860976

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200202030A ZA200202030B (en) 2001-03-12 2002-03-12 Isoindoloindolone compounds, a process for their preparation and pharmaceutical compositions containing them.

Country Status (24)

Country Link
US (1) US6465660B1 (enExample)
EP (1) EP1241169B1 (enExample)
JP (1) JP3842151B2 (enExample)
KR (1) KR100450313B1 (enExample)
CN (1) CN1159316C (enExample)
AR (1) AR034583A1 (enExample)
AT (1) ATE248171T1 (enExample)
AU (1) AU779702B2 (enExample)
BR (1) BR0200721A (enExample)
CA (1) CA2376876C (enExample)
DE (1) DE60200023T2 (enExample)
DK (1) DK1241169T3 (enExample)
EA (1) EA004035B1 (enExample)
ES (1) ES2206438T3 (enExample)
FR (1) FR2821843B1 (enExample)
HK (1) HK1049000B (enExample)
HU (1) HUP0200913A3 (enExample)
MX (1) MXPA02002601A (enExample)
NO (1) NO20021198L (enExample)
NZ (1) NZ517742A (enExample)
PL (1) PL352750A1 (enExample)
PT (1) PT1241169E (enExample)
SI (1) SI1241169T1 (enExample)
ZA (1) ZA200202030B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2826009B1 (fr) * 2001-06-13 2003-08-15 Servier Lab Nouveaux derives d'indenoindolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
SI1517909T1 (sl) * 2002-06-21 2007-06-30 Suven Life Sciences Ltd Novi tetraciklični arilkarbonil indoli, ki imajo afiniteto za serotoninski receptor, uporabni kot terapevtska sredstva, postopek za njihovo pripravo in farmacevtski sestavki, ki jih vsebujejo
BR0312175A (pt) * 2002-06-21 2005-04-05 Suven Life Sciences Ltd Composto, composição farmacêutica, uso de um composto, método para o tratamento e método para reduzir a morbidez e a mortalidade associadas com o excesso de peso
US7507835B2 (en) * 2002-11-28 2009-03-24 Suven Life Sciences Ltd. N-arylsulfonyl-3-aminoalkoxyindoles
JP4571507B2 (ja) * 2002-12-18 2010-10-27 スベン ライフ サイエンシズ リミティド セロトニン受容体親和性を有する四環系3−置換インドール
RU2387655C2 (ru) * 2004-08-09 2010-04-27 Бристол-Маерс Сквибб Компани Ингибиторы репликации вируса гепатита с
ES2580702B1 (es) 2015-02-25 2017-06-08 Palobiofarma, S.L. Derivados de 2-aminopiridina como antagonistas del receptor A2b de adenosina y ligandos del receptor MT3 de melatonina
AU2023333524A1 (en) 2022-09-02 2025-04-03 Dexcom, Inc. Continuous analyte sensor devices and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5377098A (en) * 1976-12-16 1978-07-08 Sumitomo Chem Co Ltd Preparation of indoloisoquinoline derivative
US4452808A (en) * 1982-12-07 1984-06-05 Smithkline Beckman Corporation 4-Aminoalkyl-2(3H)-indolones
US5441955A (en) * 1993-11-19 1995-08-15 Pathogenesis Corporation Indolo[2,1-biquinazoline-6,12-dione antibacterial compounds and methods of use thereof
FR2743365A1 (fr) * 1996-01-10 1997-07-11 Rhone Poulenc Rorer Sa Derives de 5h,10h-imidazo(1,2-a)indolo(3,2-e)pyrazine-4-one, leur preparation et les medicaments les contenant
US20020040018A1 (en) * 2000-06-23 2002-04-04 Jones Robert M. Subtype selective melatonergics

Also Published As

Publication number Publication date
US6465660B1 (en) 2002-10-15
CN1375494A (zh) 2002-10-23
DK1241169T3 (da) 2003-11-24
EP1241169A1 (fr) 2002-09-18
NZ517742A (en) 2003-02-28
MXPA02002601A (es) 2004-11-12
KR100450313B1 (ko) 2004-09-30
AR034583A1 (es) 2004-03-03
CA2376876C (fr) 2006-07-11
SI1241169T1 (en) 2003-12-31
BR0200721A (pt) 2002-12-03
FR2821843B1 (fr) 2003-05-09
NO20021198L (no) 2002-09-13
JP2002265469A (ja) 2002-09-18
PL352750A1 (en) 2002-09-23
HK1049000B (zh) 2005-01-07
EA004035B1 (ru) 2003-12-25
AU2324202A (en) 2002-09-19
HU0200913D0 (enExample) 2002-05-29
FR2821843A1 (fr) 2002-09-13
AU779702B2 (en) 2005-02-10
HUP0200913A2 (hu) 2002-11-28
CN1159316C (zh) 2004-07-28
EP1241169B1 (fr) 2003-08-27
EA200200241A1 (ru) 2002-10-31
HUP0200913A3 (en) 2004-11-29
HK1049000A1 (en) 2003-04-25
CA2376876A1 (fr) 2002-09-12
KR20020072782A (ko) 2002-09-18
DE60200023D1 (de) 2003-10-02
NO20021198D0 (no) 2002-03-11
ES2206438T3 (es) 2004-05-16
ATE248171T1 (de) 2003-09-15
JP3842151B2 (ja) 2006-11-08
DE60200023T2 (de) 2004-06-03
PT1241169E (pt) 2003-11-28

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