ES2195876T3 - Procedimiento para la produccion de paroxetina. - Google Patents

Procedimiento para la produccion de paroxetina.

Info

Publication number
ES2195876T3
ES2195876T3 ES00909228T ES00909228T ES2195876T3 ES 2195876 T3 ES2195876 T3 ES 2195876T3 ES 00909228 T ES00909228 T ES 00909228T ES 00909228 T ES00909228 T ES 00909228T ES 2195876 T3 ES2195876 T3 ES 2195876T3
Authority
ES
Spain
Prior art keywords
formula
compound
paroxetine
enantiomer
hydrogenation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00909228T
Other languages
English (en)
Spanish (es)
Inventor
Renzo Rossi
Stefano Turchetta
Maria Donnarumma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Recordati SA
Original Assignee
Recordati SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati SA filed Critical Recordati SA
Application granted granted Critical
Publication of ES2195876T3 publication Critical patent/ES2195876T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES00909228T 1999-02-23 2000-02-22 Procedimiento para la produccion de paroxetina. Expired - Lifetime ES2195876T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI000364A IT1308629B1 (it) 1999-02-23 1999-02-23 Processo per la produzione di paroxetina.

Publications (1)

Publication Number Publication Date
ES2195876T3 true ES2195876T3 (es) 2003-12-16

Family

ID=11382007

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00909228T Expired - Lifetime ES2195876T3 (es) 1999-02-23 2000-02-22 Procedimiento para la produccion de paroxetina.

Country Status (28)

Country Link
US (1) US6583287B1 (https=)
EP (1) EP1153023B1 (https=)
JP (1) JP2002537394A (https=)
KR (1) KR20010102366A (https=)
CN (1) CN1161353C (https=)
AT (1) ATE238295T1 (https=)
AU (1) AU759441B2 (https=)
BR (1) BR0008220A (https=)
CA (1) CA2361758A1 (https=)
CZ (1) CZ20012997A3 (https=)
DE (1) DE60002303T2 (https=)
DK (1) DK1153023T3 (https=)
ES (1) ES2195876T3 (https=)
HK (1) HK1040516B (https=)
HR (1) HRP20010608A2 (https=)
HU (1) HUP0105482A3 (https=)
IL (1) IL144883A (https=)
IT (1) IT1308629B1 (https=)
MX (1) MXPA01008502A (https=)
NO (1) NO319724B1 (https=)
PL (1) PL349358A1 (https=)
PT (1) PT1153023E (https=)
RU (1) RU2242473C2 (https=)
SK (1) SK12042001A3 (https=)
TR (1) TR200102441T2 (https=)
TW (1) TWI221473B (https=)
WO (1) WO2000050422A1 (https=)
YU (1) YU60801A (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602005001873T2 (de) * 2004-03-03 2008-04-24 Chemi S.P.A., Cinisello Balsamo Amorphe 3-Pyridyl-1-Hydroxyethyliden-1,1-Bisphosphonsäure Mononatriumsalz und Verfahren zu deren Herstellung
US9138430B2 (en) * 2007-12-27 2015-09-22 Mylan Specialty L.P. Formulation and method for the release of paroxetine in the large intestine
ES2576082T3 (es) * 2012-01-31 2016-07-05 Eisai R&D Management Co., Ltd. Derivado de paroxetina
CN106831736A (zh) * 2017-02-15 2017-06-13 浙江华海药业股份有限公司 一种制备帕罗西汀杂质的方法
CN112521377A (zh) * 2020-11-26 2021-03-19 北京福元医药股份有限公司 一种盐酸帕罗西汀的连续化制备方法
CN115260153B (zh) * 2022-07-21 2023-10-27 威尚（上海）生物医药有限公司 一种6取代手性纯二氟哌啶喹唑啉衍生物及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0757758B2 (ja) 1988-10-24 1995-06-21 高砂香料工業株式会社 ルテニウム―ホスフィン錯体
DK715988D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Etherifikation og dealkylering af piperidin-derivater samt intermediater
US5233084A (en) 1989-06-22 1993-08-03 Monsanto Company Method for preparing α-arylpropionic acids
FR2651152B1 (fr) * 1989-08-23 1991-11-29 Elf Aquitaine Perfectionnement a la preparation de catalyseurs chiraux a base de complexes du ruthenium et du phosphore.
GB9209687D0 (en) 1992-05-06 1992-06-17 Smithkline Beecham Plc Novel process
DE4422672A1 (de) * 1994-06-30 1996-01-04 Hoechst Ag Halogenierte Biphenyl-2,2'-diyl-bis-diphenylphosphine, ihre Herstellung und ihre Verwendung
SK283608B6 (sk) * 1995-02-06 2003-10-07 Smithkline Beecham Plc Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie
HUP9900318A3 (en) * 1995-05-17 2001-09-28 Novo Nordisk As Process for preparing 4-aryl-piperidine derivatives
HU221921B1 (hu) * 1996-07-08 2003-02-28 Richter Gedeon Vegyészeti Gyár Rt. N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására
IL132170A0 (en) * 1997-05-06 2001-03-19 Novo Nordisk As Novel heterocyclic compounds
DE69820205T2 (de) * 1997-05-20 2004-09-30 Firmenich S.A. Ruthenium-katalysatoren und ihre verwendung zur asymmetrischen hydrierung von substraten mit schwacher koordination

Also Published As

Publication number Publication date
NO319724B1 (no) 2005-09-05
CZ20012997A3 (cs) 2001-11-14
WO2000050422A1 (en) 2000-08-31
YU60801A (sh) 2005-07-19
CN1161353C (zh) 2004-08-11
IL144883A0 (en) 2002-06-30
TWI221473B (en) 2004-10-01
RU2242473C2 (ru) 2004-12-20
HUP0105482A3 (en) 2002-11-28
ITMI990364A1 (it) 2000-08-23
CA2361758A1 (en) 2000-08-31
NO20014078L (no) 2001-10-18
US6583287B1 (en) 2003-06-24
TR200102441T2 (tr) 2002-01-21
HUP0105482A2 (en) 2002-08-28
PL349358A1 (en) 2002-07-15
HK1040516A1 (en) 2002-06-14
CN1341113A (zh) 2002-03-20
AU3158300A (en) 2000-09-14
KR20010102366A (ko) 2001-11-15
DE60002303T2 (de) 2004-04-01
BR0008220A (pt) 2001-11-06
SK12042001A3 (sk) 2001-12-03
EP1153023A1 (en) 2001-11-14
AU759441B2 (en) 2003-04-17
IL144883A (en) 2004-12-15
MXPA01008502A (es) 2003-06-06
EP1153023B1 (en) 2003-04-23
HRP20010608A2 (en) 2002-08-31
ATE238295T1 (de) 2003-05-15
NO20014078D0 (no) 2001-08-22
DK1153023T3 (da) 2003-08-11
IT1308629B1 (it) 2002-01-09
JP2002537394A (ja) 2002-11-05
HK1040516B (en) 2003-10-31
DE60002303D1 (de) 2003-05-28
PT1153023E (pt) 2003-09-30

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