JP2002537394A - パロキセチンの製造方法 - Google Patents

パロキセチンの製造方法

Info

Publication number
JP2002537394A
JP2002537394A JP2000601002A JP2000601002A JP2002537394A JP 2002537394 A JP2002537394 A JP 2002537394A JP 2000601002 A JP2000601002 A JP 2000601002A JP 2000601002 A JP2000601002 A JP 2000601002A JP 2002537394 A JP2002537394 A JP 2002537394A
Authority
JP
Japan
Prior art keywords
compound
binap
formula
complex
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000601002A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002537394A5 (https=
Inventor
ロッシ・レンゾ
チェルチェッタ・ステファノ
ドッナルッマ・マリア
Original Assignee
レコーダチ エス．エイ．ケミカル アンド ファルマチェウティカル カンパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by レコーダチ エス．エイ．ケミカル アンド ファルマチェウティカル カンパニー filed Critical レコーダチ エス．エイ．ケミカル アンド ファルマチェウティカル カンパニー
Publication of JP2002537394A publication Critical patent/JP2002537394A/ja
Publication of JP2002537394A5 publication Critical patent/JP2002537394A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2000601002A 1999-02-23 2000-02-22 パロキセチンの製造方法 Pending JP2002537394A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT1999MI000364A IT1308629B1 (it) 1999-02-23 1999-02-23 Processo per la produzione di paroxetina.
IT99A0000364 1999-02-23
PCT/EP2000/001430 WO2000050422A1 (en) 1999-02-23 2000-02-22 Process for the production of paroxetine

Publications (2)

Publication Number Publication Date
JP2002537394A true JP2002537394A (ja) 2002-11-05
JP2002537394A5 JP2002537394A5 (https=) 2007-04-12

Family

ID=11382007

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000601002A Pending JP2002537394A (ja) 1999-02-23 2000-02-22 パロキセチンの製造方法

Country Status (28)

Country Link
US (1) US6583287B1 (https=)
EP (1) EP1153023B1 (https=)
JP (1) JP2002537394A (https=)
KR (1) KR20010102366A (https=)
CN (1) CN1161353C (https=)
AT (1) ATE238295T1 (https=)
AU (1) AU759441B2 (https=)
BR (1) BR0008220A (https=)
CA (1) CA2361758A1 (https=)
CZ (1) CZ20012997A3 (https=)
DE (1) DE60002303T2 (https=)
DK (1) DK1153023T3 (https=)
ES (1) ES2195876T3 (https=)
HK (1) HK1040516B (https=)
HR (1) HRP20010608A2 (https=)
HU (1) HUP0105482A3 (https=)
IL (1) IL144883A (https=)
IT (1) IT1308629B1 (https=)
MX (1) MXPA01008502A (https=)
NO (1) NO319724B1 (https=)
PL (1) PL349358A1 (https=)
PT (1) PT1153023E (https=)
RU (1) RU2242473C2 (https=)
SK (1) SK12042001A3 (https=)
TR (1) TR200102441T2 (https=)
TW (1) TWI221473B (https=)
WO (1) WO2000050422A1 (https=)
YU (1) YU60801A (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602005001873T2 (de) * 2004-03-03 2008-04-24 Chemi S.P.A., Cinisello Balsamo Amorphe 3-Pyridyl-1-Hydroxyethyliden-1,1-Bisphosphonsäure Mononatriumsalz und Verfahren zu deren Herstellung
US9138430B2 (en) * 2007-12-27 2015-09-22 Mylan Specialty L.P. Formulation and method for the release of paroxetine in the large intestine
ES2576082T3 (es) * 2012-01-31 2016-07-05 Eisai R&D Management Co., Ltd. Derivado de paroxetina
CN106831736A (zh) * 2017-02-15 2017-06-13 浙江华海药业股份有限公司 一种制备帕罗西汀杂质的方法
CN112521377A (zh) * 2020-11-26 2021-03-19 北京福元医药股份有限公司 一种盐酸帕罗西汀的连续化制备方法
CN115260153B (zh) * 2022-07-21 2023-10-27 威尚（上海）生物医药有限公司 一种6取代手性纯二氟哌啶喹唑啉衍生物及其制备方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02225464A (ja) * 1988-12-22 1990-09-07 Ferrosan:As ピペリジン誘導体のエーテル化及び脱アルキル化及び中間体
JPH05500023A (ja) * 1989-08-23 1993-01-14 ソシエテ・ナショナール・エルフ・アキテーヌ ルテニウムおよびリン錯体にもとづくキラル触媒の製造方法の改良
JPH0853480A (ja) * 1994-06-30 1996-02-27 Hoechst Ag ハロゲン化ビフェニル−２，２′−ジイルビスジフェニルホスフィンおよびそれらの製法
WO1996036636A1 (en) * 1995-05-17 1996-11-21 Novo Nordisk A/S Process for preparing 4-aryl-piperidine derivatives
WO1998001424A1 (en) * 1996-07-08 1998-01-15 Richter Gedeon Vegyészeti Gyár Rt. N-benzylpiperidine and tetrahydropyridine derivatives
WO1998050359A1 (en) * 1997-05-06 1998-11-12 Novo Nordisk A/S Novel heterocyclic compounds
WO1998052687A1 (en) * 1997-05-20 1998-11-26 Firmenich S.A. Ruthenium catalysts and their use in the asymmetric hydrogenation of weakly coordinating substrates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0757758B2 (ja) 1988-10-24 1995-06-21 高砂香料工業株式会社 ルテニウム―ホスフィン錯体
US5233084A (en) 1989-06-22 1993-08-03 Monsanto Company Method for preparing α-arylpropionic acids
GB9209687D0 (en) 1992-05-06 1992-06-17 Smithkline Beecham Plc Novel process
SK283608B6 (sk) * 1995-02-06 2003-10-07 Smithkline Beecham Plc Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02225464A (ja) * 1988-12-22 1990-09-07 Ferrosan:As ピペリジン誘導体のエーテル化及び脱アルキル化及び中間体
JPH05500023A (ja) * 1989-08-23 1993-01-14 ソシエテ・ナショナール・エルフ・アキテーヌ ルテニウムおよびリン錯体にもとづくキラル触媒の製造方法の改良
JPH0853480A (ja) * 1994-06-30 1996-02-27 Hoechst Ag ハロゲン化ビフェニル−２，２′−ジイルビスジフェニルホスフィンおよびそれらの製法
WO1996036636A1 (en) * 1995-05-17 1996-11-21 Novo Nordisk A/S Process for preparing 4-aryl-piperidine derivatives
WO1998001424A1 (en) * 1996-07-08 1998-01-15 Richter Gedeon Vegyészeti Gyár Rt. N-benzylpiperidine and tetrahydropyridine derivatives
WO1998050359A1 (en) * 1997-05-06 1998-11-12 Novo Nordisk A/S Novel heterocyclic compounds
WO1998052687A1 (en) * 1997-05-20 1998-11-26 Firmenich S.A. Ruthenium catalysts and their use in the asymmetric hydrogenation of weakly coordinating substrates

Also Published As

Publication number Publication date
NO319724B1 (no) 2005-09-05
CZ20012997A3 (cs) 2001-11-14
WO2000050422A1 (en) 2000-08-31
YU60801A (sh) 2005-07-19
CN1161353C (zh) 2004-08-11
IL144883A0 (en) 2002-06-30
TWI221473B (en) 2004-10-01
RU2242473C2 (ru) 2004-12-20
HUP0105482A3 (en) 2002-11-28
ITMI990364A1 (it) 2000-08-23
CA2361758A1 (en) 2000-08-31
NO20014078L (no) 2001-10-18
US6583287B1 (en) 2003-06-24
TR200102441T2 (tr) 2002-01-21
HUP0105482A2 (en) 2002-08-28
PL349358A1 (en) 2002-07-15
HK1040516A1 (en) 2002-06-14
CN1341113A (zh) 2002-03-20
AU3158300A (en) 2000-09-14
KR20010102366A (ko) 2001-11-15
DE60002303T2 (de) 2004-04-01
BR0008220A (pt) 2001-11-06
SK12042001A3 (sk) 2001-12-03
EP1153023A1 (en) 2001-11-14
ES2195876T3 (es) 2003-12-16
AU759441B2 (en) 2003-04-17
IL144883A (en) 2004-12-15
MXPA01008502A (es) 2003-06-06
EP1153023B1 (en) 2003-04-23
HRP20010608A2 (en) 2002-08-31
ATE238295T1 (de) 2003-05-15
NO20014078D0 (no) 2001-08-22
DK1153023T3 (da) 2003-08-11
IT1308629B1 (it) 2002-01-09
HK1040516B (en) 2003-10-31
DE60002303D1 (de) 2003-05-28
PT1153023E (pt) 2003-09-30

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