JP2002537394A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2002537394A5 JP2002537394A5 JP2000601002A JP2000601002A JP2002537394A5 JP 2002537394 A5 JP2002537394 A5 JP 2002537394A5 JP 2000601002 A JP2000601002 A JP 2000601002A JP 2000601002 A JP2000601002 A JP 2000601002A JP 2002537394 A5 JP2002537394 A5 JP 2002537394A5
- Authority
- JP
- Japan
- Prior art keywords
- binap
- trans
- compound
- mixture
- cis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 OCC(C*CC1)[C@@]1c(cc1)ccc1F Chemical compound OCC(C*CC1)[C@@]1c(cc1)ccc1F 0.000 description 1
- ZSYVGBLSRONTAI-UHFFFAOYSA-N OCC1C(c(cc2)ccc2F)=CCNC1 Chemical compound OCC1C(c(cc2)ccc2F)=CCNC1 ZSYVGBLSRONTAI-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT1999MI000364A IT1308629B1 (it) | 1999-02-23 | 1999-02-23 | Processo per la produzione di paroxetina. |
| IT99A0000364 | 1999-02-23 | ||
| PCT/EP2000/001430 WO2000050422A1 (en) | 1999-02-23 | 2000-02-22 | Process for the production of paroxetine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002537394A JP2002537394A (ja) | 2002-11-05 |
| JP2002537394A5 true JP2002537394A5 (https=) | 2007-04-12 |
Family
ID=11382007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000601002A Pending JP2002537394A (ja) | 1999-02-23 | 2000-02-22 | パロキセチンの製造方法 |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6583287B1 (https=) |
| EP (1) | EP1153023B1 (https=) |
| JP (1) | JP2002537394A (https=) |
| KR (1) | KR20010102366A (https=) |
| CN (1) | CN1161353C (https=) |
| AT (1) | ATE238295T1 (https=) |
| AU (1) | AU759441B2 (https=) |
| BR (1) | BR0008220A (https=) |
| CA (1) | CA2361758A1 (https=) |
| CZ (1) | CZ20012997A3 (https=) |
| DE (1) | DE60002303T2 (https=) |
| DK (1) | DK1153023T3 (https=) |
| ES (1) | ES2195876T3 (https=) |
| HK (1) | HK1040516B (https=) |
| HR (1) | HRP20010608A2 (https=) |
| HU (1) | HUP0105482A3 (https=) |
| IL (1) | IL144883A (https=) |
| IT (1) | IT1308629B1 (https=) |
| MX (1) | MXPA01008502A (https=) |
| NO (1) | NO319724B1 (https=) |
| PL (1) | PL349358A1 (https=) |
| PT (1) | PT1153023E (https=) |
| RU (1) | RU2242473C2 (https=) |
| SK (1) | SK12042001A3 (https=) |
| TR (1) | TR200102441T2 (https=) |
| TW (1) | TWI221473B (https=) |
| WO (1) | WO2000050422A1 (https=) |
| YU (1) | YU60801A (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602005001873T2 (de) * | 2004-03-03 | 2008-04-24 | Chemi S.P.A., Cinisello Balsamo | Amorphe 3-Pyridyl-1-Hydroxyethyliden-1,1-Bisphosphonsäure Mononatriumsalz und Verfahren zu deren Herstellung |
| US9138430B2 (en) * | 2007-12-27 | 2015-09-22 | Mylan Specialty L.P. | Formulation and method for the release of paroxetine in the large intestine |
| ES2576082T3 (es) * | 2012-01-31 | 2016-07-05 | Eisai R&D Management Co., Ltd. | Derivado de paroxetina |
| CN106831736A (zh) * | 2017-02-15 | 2017-06-13 | 浙江华海药业股份有限公司 | 一种制备帕罗西汀杂质的方法 |
| CN112521377A (zh) * | 2020-11-26 | 2021-03-19 | 北京福元医药股份有限公司 | 一种盐酸帕罗西汀的连续化制备方法 |
| CN115260153B (zh) * | 2022-07-21 | 2023-10-27 | 威尚（上海）生物医药有限公司 | 一种6取代手性纯二氟哌啶喹唑啉衍生物及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0757758B2 (ja) | 1988-10-24 | 1995-06-21 | 高砂香料工業株式会社 | ルテニウム―ホスフィン錯体 |
| DK715988D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Etherifikation og dealkylering af piperidin-derivater samt intermediater |
| US5233084A (en) | 1989-06-22 | 1993-08-03 | Monsanto Company | Method for preparing α-arylpropionic acids |
| FR2651152B1 (fr) * | 1989-08-23 | 1991-11-29 | Elf Aquitaine | Perfectionnement a la preparation de catalyseurs chiraux a base de complexes du ruthenium et du phosphore. |
| GB9209687D0 (en) | 1992-05-06 | 1992-06-17 | Smithkline Beecham Plc | Novel process |
| DE4422672A1 (de) * | 1994-06-30 | 1996-01-04 | Hoechst Ag | Halogenierte Biphenyl-2,2'-diyl-bis-diphenylphosphine, ihre Herstellung und ihre Verwendung |
| SK283608B6 (sk) * | 1995-02-06 | 2003-10-07 | Smithkline Beecham Plc | Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie |
| HUP9900318A3 (en) * | 1995-05-17 | 2001-09-28 | Novo Nordisk As | Process for preparing 4-aryl-piperidine derivatives |
| HU221921B1 (hu) * | 1996-07-08 | 2003-02-28 | Richter Gedeon Vegyészeti Gyár Rt. | N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására |
| IL132170A0 (en) * | 1997-05-06 | 2001-03-19 | Novo Nordisk As | Novel heterocyclic compounds |
| DE69820205T2 (de) * | 1997-05-20 | 2004-09-30 | Firmenich S.A. | Ruthenium-katalysatoren und ihre verwendung zur asymmetrischen hydrierung von substraten mit schwacher koordination |
-
1999
- 1999-02-23 IT IT1999MI000364A patent/IT1308629B1/it active
-
2000
- 2000-02-18 TW TW089102997A patent/TWI221473B/zh not_active IP Right Cessation
- 2000-02-22 EP EP00909228A patent/EP1153023B1/en not_active Expired - Lifetime
- 2000-02-22 US US09/890,414 patent/US6583287B1/en not_active Expired - Fee Related
- 2000-02-22 JP JP2000601002A patent/JP2002537394A/ja active Pending
- 2000-02-22 AT AT00909228T patent/ATE238295T1/de not_active IP Right Cessation
- 2000-02-22 CZ CZ20012997A patent/CZ20012997A3/cs unknown
- 2000-02-22 CN CNB008041873A patent/CN1161353C/zh not_active Expired - Fee Related
- 2000-02-22 BR BR0008220-1A patent/BR0008220A/pt not_active IP Right Cessation
- 2000-02-22 PT PT00909228T patent/PT1153023E/pt unknown
- 2000-02-22 DK DK00909228T patent/DK1153023T3/da active
- 2000-02-22 IL IL14488300A patent/IL144883A/en not_active IP Right Cessation
- 2000-02-22 HK HK02101971.9A patent/HK1040516B/en not_active IP Right Cessation
- 2000-02-22 PL PL00349358A patent/PL349358A1/xx not_active IP Right Cessation
- 2000-02-22 DE DE60002303T patent/DE60002303T2/de not_active Expired - Fee Related
- 2000-02-22 MX MXPA01008502A patent/MXPA01008502A/es active IP Right Grant
- 2000-02-22 WO PCT/EP2000/001430 patent/WO2000050422A1/en not_active Ceased
- 2000-02-22 SK SK1204-2001A patent/SK12042001A3/sk unknown
- 2000-02-22 TR TR2001/02441T patent/TR200102441T2/xx unknown
- 2000-02-22 AU AU31583/00A patent/AU759441B2/en not_active Ceased
- 2000-02-22 HU HU0105482A patent/HUP0105482A3/hu unknown
- 2000-02-22 HR HR20010608A patent/HRP20010608A2/hr not_active Application Discontinuation
- 2000-02-22 RU RU2001125933/04A patent/RU2242473C2/ru not_active IP Right Cessation
- 2000-02-22 CA CA002361758A patent/CA2361758A1/en not_active Abandoned
- 2000-02-22 ES ES00909228T patent/ES2195876T3/es not_active Expired - Lifetime
- 2000-02-22 KR KR1020017010760A patent/KR20010102366A/ko not_active Ceased
- 2000-02-22 YU YU60801A patent/YU60801A/sh unknown
-
2001
- 2001-08-22 NO NO20014078A patent/NO319724B1/no unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RS60801B1 (sr) | Tečni farmaceutski sastav | |
| EP0759904B1 (en) | Process and diastereomeric salts useful for the optical resolution of racemic 4-[4-[-4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-alpha,alpha-dimethylbenzene acetic acid. | |
| JP6917949B2 (ja) | トファシチニブの調製のための有用な中間体であるキラル３−アミノ−ピペリジンの調製のための改良された方法 | |
| US5965734A (en) | Processes and intermediates for preparing 2-substituted piperidine stereoisomers | |
| JP2002537394A5 (https=) | ||
| US6583287B1 (en) | Process for the production of paroxetine | |
| US6444822B1 (en) | Process for the preparation of 3-substituted 4-phenyl-piperidine derivative | |
| JPH0421662B2 (https=) | ||
| JP2008506746A (ja) | ジアステレオマーに富んだ化合物の調製方法 | |
| US20010053862A1 (en) | Process for preparing arylpiperidine carbinol intermediates and derivatives | |
| JPS63503384A (ja) | １‐置換（ｓ）‐および（ｒ）‐２‐アミノメチルピロリジン類の有効な立体保存的合成およびその中間体 | |
| JPH10279552A (ja) | ７−（ｎ−置換アミノ）−２−フェニルヘプタン酸 エステル誘導体及び該誘導体の製造方法 | |
| US5300660A (en) | Efficient stereoconservative synthesis of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines and intermediates thereto | |
| KR20040050942A (ko) | 파록세틴의 제조방법 | |
| KR20100022272A (ko) | 신규한 ｓ-(-)-암로디핀 제조방법 | |
| EP1140832A1 (en) | Process for preparing arylpiperidine carbinol intermediates and derivatives | |
| JPH07133258A (ja) | ２，５−ピロリジンジオン誘導体 |