BR0008220A - Processo para produção de paroxetina - Google Patents

Processo para produção de paroxetina

Info

Publication number
BR0008220A
BR0008220A BR0008220-1A BR0008220A BR0008220A BR 0008220 A BR0008220 A BR 0008220A BR 0008220 A BR0008220 A BR 0008220A BR 0008220 A BR0008220 A BR 0008220A
Authority
BR
Brazil
Prior art keywords
paroxetine
production
sesamol
dealkylation
tetrahydropyridine
Prior art date
Application number
BR0008220-1A
Other languages
English (en)
Portuguese (pt)
Inventor
Renzo Rossi
Stefano Turchetta
Maria Donnarumma
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of BR0008220A publication Critical patent/BR0008220A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BR0008220-1A 1999-02-23 2000-02-22 Processo para produção de paroxetina BR0008220A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI000364A IT1308629B1 (it) 1999-02-23 1999-02-23 Processo per la produzione di paroxetina.
PCT/EP2000/001430 WO2000050422A1 (en) 1999-02-23 2000-02-22 Process for the production of paroxetine

Publications (1)

Publication Number Publication Date
BR0008220A true BR0008220A (pt) 2001-11-06

Family

ID=11382007

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008220-1A BR0008220A (pt) 1999-02-23 2000-02-22 Processo para produção de paroxetina

Country Status (28)

Country Link
US (1) US6583287B1 (https=)
EP (1) EP1153023B1 (https=)
JP (1) JP2002537394A (https=)
KR (1) KR20010102366A (https=)
CN (1) CN1161353C (https=)
AT (1) ATE238295T1 (https=)
AU (1) AU759441B2 (https=)
BR (1) BR0008220A (https=)
CA (1) CA2361758A1 (https=)
CZ (1) CZ20012997A3 (https=)
DE (1) DE60002303T2 (https=)
DK (1) DK1153023T3 (https=)
ES (1) ES2195876T3 (https=)
HK (1) HK1040516B (https=)
HR (1) HRP20010608A2 (https=)
HU (1) HUP0105482A3 (https=)
IL (1) IL144883A (https=)
IT (1) IT1308629B1 (https=)
MX (1) MXPA01008502A (https=)
NO (1) NO319724B1 (https=)
PL (1) PL349358A1 (https=)
PT (1) PT1153023E (https=)
RU (1) RU2242473C2 (https=)
SK (1) SK12042001A3 (https=)
TR (1) TR200102441T2 (https=)
TW (1) TWI221473B (https=)
WO (1) WO2000050422A1 (https=)
YU (1) YU60801A (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1571152B1 (en) * 2004-03-03 2007-08-08 CHEMI S.p.A. Amorphous 3-Pyridil-1-Hydroxyethyliden-1,1-Biphosphonic acid monosodium salt and process for the preparation thereof .
US9138430B2 (en) * 2007-12-27 2015-09-22 Mylan Specialty L.P. Formulation and method for the release of paroxetine in the large intestine
WO2013115163A1 (ja) * 2012-01-31 2013-08-08 エーザイ・アール・アンド・ディー・マネジメント株式会社 パロキセチン誘導体
CN106831736A (zh) * 2017-02-15 2017-06-13 浙江华海药业股份有限公司 一种制备帕罗西汀杂质的方法
CN112521377A (zh) * 2020-11-26 2021-03-19 北京福元医药股份有限公司 一种盐酸帕罗西汀的连续化制备方法
CN115260153B (zh) * 2022-07-21 2023-10-27 威尚（上海）生物医药有限公司 一种6取代手性纯二氟哌啶喹唑啉衍生物及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0757758B2 (ja) 1988-10-24 1995-06-21 高砂香料工業株式会社 ルテニウム―ホスフィン錯体
DK715988D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Etherifikation og dealkylering af piperidin-derivater samt intermediater
US5233084A (en) * 1989-06-22 1993-08-03 Monsanto Company Method for preparing α-arylpropionic acids
FR2651152B1 (fr) * 1989-08-23 1991-11-29 Elf Aquitaine Perfectionnement a la preparation de catalyseurs chiraux a base de complexes du ruthenium et du phosphore.
GB9209687D0 (en) * 1992-05-06 1992-06-17 Smithkline Beecham Plc Novel process
DE4422672A1 (de) * 1994-06-30 1996-01-04 Hoechst Ag Halogenierte Biphenyl-2,2'-diyl-bis-diphenylphosphine, ihre Herstellung und ihre Verwendung
AR001982A1 (es) * 1995-02-06 1998-01-07 Smithkline Beecham Plc Clorhidrato de paroxetina anhidratado, y procedimiento para su preparacion
CN1068597C (zh) 1995-05-17 2001-07-18 诺沃挪第克公司 制备4－芳基－哌啶衍生物的方法
HU221921B1 (hu) * 1996-07-08 2003-02-28 Richter Gedeon Vegyészeti Gyár Rt. N-benzil-piperidin- és tetrahidropiridinszármazékok és eljárás azok előállítására
WO1998050359A1 (en) * 1997-05-06 1998-11-12 Novo Nordisk A/S Novel heterocyclic compounds
ES2212287T3 (es) * 1997-05-20 2004-07-16 Firmenich Sa Catalizadores de rutenio y su uso en la hidrogenacion asimetrica de sustratos debilmente coordinantes.

Also Published As

Publication number Publication date
ATE238295T1 (de) 2003-05-15
CZ20012997A3 (cs) 2001-11-14
DK1153023T3 (da) 2003-08-11
HK1040516B (en) 2003-10-31
DE60002303T2 (de) 2004-04-01
HUP0105482A3 (en) 2002-11-28
SK12042001A3 (sk) 2001-12-03
MXPA01008502A (es) 2003-06-06
HK1040516A1 (en) 2002-06-14
EP1153023B1 (en) 2003-04-23
ITMI990364A1 (it) 2000-08-23
WO2000050422A1 (en) 2000-08-31
YU60801A (sh) 2005-07-19
NO20014078D0 (no) 2001-08-22
CN1341113A (zh) 2002-03-20
HRP20010608A2 (en) 2002-08-31
KR20010102366A (ko) 2001-11-15
AU3158300A (en) 2000-09-14
CA2361758A1 (en) 2000-08-31
NO319724B1 (no) 2005-09-05
HUP0105482A2 (en) 2002-08-28
TWI221473B (en) 2004-10-01
ES2195876T3 (es) 2003-12-16
IL144883A (en) 2004-12-15
DE60002303D1 (de) 2003-05-28
US6583287B1 (en) 2003-06-24
TR200102441T2 (tr) 2002-01-21
JP2002537394A (ja) 2002-11-05
RU2242473C2 (ru) 2004-12-20
PL349358A1 (en) 2002-07-15
IT1308629B1 (it) 2002-01-09
IL144883A0 (en) 2002-06-30
AU759441B2 (en) 2003-04-17
PT1153023E (pt) 2003-09-30
CN1161353C (zh) 2004-08-11
EP1153023A1 (en) 2001-11-14
NO20014078L (no) 2001-10-18

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A, 8A E 9A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 NA RPI2003 DE 26/05/2009.