ATE223414T1 - Prozess zur herstellung von zwischebprodukten für imidazodeazepinen - Google Patents

Prozess zur herstellung von zwischebprodukten für imidazodeazepinen

Info

Publication number
ATE223414T1
ATE223414T1 AT00944685T AT00944685T ATE223414T1 AT E223414 T1 ATE223414 T1 AT E223414T1 AT 00944685 T AT00944685 T AT 00944685T AT 00944685 T AT00944685 T AT 00944685T AT E223414 T1 ATE223414 T1 AT E223414T1
Authority
AT
Austria
Prior art keywords
imidazodeazepines
intermediate products
producing intermediate
producing
compound
Prior art date
Application number
AT00944685T
Other languages
English (en)
Inventor
Madhup K Dhaon
Parvis Labib
Deborah A Davis
Grant L Esser
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE223414T1 publication Critical patent/ATE223414T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT00944685T 1999-06-30 2000-06-15 Prozess zur herstellung von zwischebprodukten für imidazodeazepinen ATE223414T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/343,317 US20010014738A1 (en) 1999-06-30 1999-06-30 Process for the preparation of imidazodiazepine intermediates
PCT/US2000/016476 WO2001000625A1 (en) 1999-06-30 2000-06-15 Process for the preparation of imidazodiazepine intermediates

Publications (1)

Publication Number Publication Date
ATE223414T1 true ATE223414T1 (de) 2002-09-15

Family

ID=23345595

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00944685T ATE223414T1 (de) 1999-06-30 2000-06-15 Prozess zur herstellung von zwischebprodukten für imidazodeazepinen

Country Status (14)

Country Link
US (1) US20010014738A1 (de)
EP (2) EP1105392B1 (de)
JP (1) JP2003503410A (de)
KR (1) KR20010079706A (de)
CN (1) CN1315953A (de)
AT (1) ATE223414T1 (de)
AU (1) AU5874600A (de)
CA (1) CA2341524A1 (de)
DE (1) DE60000402T2 (de)
DK (1) DK1105392T3 (de)
ES (1) ES2185599T3 (de)
IL (1) IL141394A0 (de)
PT (1) PT1105392E (de)
WO (1) WO2001000625A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0211350D0 (en) 2002-05-16 2002-06-26 Rolls Royce Plc A gas turbine engine
IL156606A (en) 2003-06-23 2011-07-31 Aviad Kipnis Digital certificates
IT1399764B1 (it) * 2010-05-04 2013-05-03 F S I Fabbrica Italiana Sint Procedimento per la sintesi di 4h-imidazo [1,5-a][1,4]benzodiazepine, in particolare di midazolam.
CN103086986B (zh) * 2011-11-01 2015-11-04 上海医药工业研究院 1,4-苯二氮卓-n-亚硝胺类中间体的制备方法及其应用
CN103319486B (zh) * 2012-03-22 2017-10-10 徐州市心血管病研究所 合成4H‑咪唑并[1,5‑a][1,4]苯二氮卓,特别是咪达唑仑的方法
CN106032380A (zh) * 2015-03-16 2016-10-19 王志训 一种咪达唑仑的工业制造方法
CN106032381A (zh) * 2015-03-16 2016-10-19 王志训 一种咪达唑仑衍生物的工业制造方法
WO2018035246A1 (en) 2016-08-16 2018-02-22 Uwm Research Foundation, Inc. Gaba(a) receptor modulators and methods to control airway hyperresponsiveness and inflammation in asthma

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4440685A (en) * 1974-09-11 1984-04-03 Hoffmann-La Roche Inc. Imidazodiazepines and processes therefor
US4307237A (en) * 1974-09-11 1981-12-22 Hoffmann-La Roche Inc. Imidazoles
US4335042A (en) * 1980-04-21 1982-06-15 Hoffmann-La Roche Inc. Process to produce imidazobenzodiazepine intermediates

Also Published As

Publication number Publication date
IL141394A0 (en) 2002-03-10
JP2003503410A (ja) 2003-01-28
CA2341524A1 (en) 2001-01-04
HK1037617A1 (en) 2002-02-15
DK1105392T3 (da) 2002-12-30
EP1105392B1 (de) 2002-09-04
KR20010079706A (ko) 2001-08-22
CN1315953A (zh) 2001-10-03
ES2185599T3 (es) 2003-05-01
EP1199308A3 (de) 2002-05-02
DE60000402D1 (de) 2002-10-10
EP1105392A1 (de) 2001-06-13
EP1199308A2 (de) 2002-04-24
DE60000402T2 (de) 2003-05-22
PT1105392E (pt) 2002-12-31
AU5874600A (en) 2001-01-31
US20010014738A1 (en) 2001-08-16
WO2001000625A1 (en) 2001-01-04

Similar Documents

Publication Publication Date Title
ATE300528T1 (de) Synthese von cannabinoiden
ATE452882T1 (de) Herstellung von quetiapin
PT841344E (pt) 1-(2-desoxi-2-fluoro-4-tio-beta-d-arabinofuranosil) citosinas
ATE223414T1 (de) Prozess zur herstellung von zwischebprodukten für imidazodeazepinen
DE60235365D1 (de) Verfahren zur herstellung von 7-amino-syn-3,5-dihydroxyheptansäurederivaten und zwischenverbindungen diesesverfahrens und deren herestellung
PT829473E (pt) Processos para a preparacao de compostos ciclicos
PT1206452E (pt) Processo de preparacao de compostos benzoper-hidroisoindole
FI955954A0 (fi) Thiolyhdisteitä
DE60305003D1 (de) Verfahren zur herstellung von synergistischen stabilisatorgemischen
DE60116201D1 (de) Verfahren zur Herstellung von Cephalosporin-Verbindungen und Zwischenprodukte für die Synthese dieser Verbindungen
BR0214445B1 (pt) processos para a produção de compostos.
ATE247641T1 (de) Pyridin-zwischenprodukte, verwendbar zur herstellung von beta-adrenergischen rezeptor- agonisten
ATE348815T1 (de) Synthese von zwischenprodukten zur herstellung von tricyclischen verbindungen
ATE244262T1 (de) Verfahren zur herstellung von peptidzwischenprodukten
ATE244228T1 (de) Verfahren zur herstellung von chloroacetylaminothiazoleaceticsäure derivate
DE50312447D1 (de) Verfahren zur herstellung von 4,6-dichlor-5-fluorpyrimidin
DE60127979D1 (de) Verfahren zur herstellung von 3,5-bisalkylphenolen
TW200420553A (en) Process for the synthesis of 3, 3a, 6, 6a-tetrahydro-2H-cyclopentan[b]furan-2-one
DE50204538D1 (de) Verfahren zur herstellung von biperiden iv
DE69816095D1 (de) Herstellung von beta-mehtylcarbapenem-zwischenprodukten

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1105392

Country of ref document: EP

REN Ceased due to non-payment of the annual fee