PT1105392E - Processo para a preparacao de intermediarios de imidazodiazepina - Google Patents

Processo para a preparacao de intermediarios de imidazodiazepina

Info

Publication number
PT1105392E
PT1105392E PT00944685T PT00944685T PT1105392E PT 1105392 E PT1105392 E PT 1105392E PT 00944685 T PT00944685 T PT 00944685T PT 00944685 T PT00944685 T PT 00944685T PT 1105392 E PT1105392 E PT 1105392E
Authority
PT
Portugal
Prior art keywords
imidazodiazepine
intermediaries
preparation
compound
formula
Prior art date
Application number
PT00944685T
Other languages
English (en)
Inventor
Madhup K Dhaon
Parvis Labib
Deborah A Davis
Grant L Esser
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of PT1105392E publication Critical patent/PT1105392E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
PT00944685T 1999-06-30 2000-06-15 Processo para a preparacao de intermediarios de imidazodiazepina PT1105392E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/343,317 US20010014738A1 (en) 1999-06-30 1999-06-30 Process for the preparation of imidazodiazepine intermediates

Publications (1)

Publication Number Publication Date
PT1105392E true PT1105392E (pt) 2002-12-31

Family

ID=23345595

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00944685T PT1105392E (pt) 1999-06-30 2000-06-15 Processo para a preparacao de intermediarios de imidazodiazepina

Country Status (15)

Country Link
US (1) US20010014738A1 (pt)
EP (2) EP1105392B1 (pt)
JP (1) JP2003503410A (pt)
KR (1) KR20010079706A (pt)
CN (1) CN1315953A (pt)
AT (1) ATE223414T1 (pt)
AU (1) AU5874600A (pt)
CA (1) CA2341524A1 (pt)
DE (1) DE60000402T2 (pt)
DK (1) DK1105392T3 (pt)
ES (1) ES2185599T3 (pt)
HK (1) HK1037617A1 (pt)
IL (1) IL141394A0 (pt)
PT (1) PT1105392E (pt)
WO (1) WO2001000625A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0211350D0 (en) 2002-05-16 2002-06-26 Rolls Royce Plc A gas turbine engine
IL156606A (en) 2003-06-23 2011-07-31 Aviad Kipnis Digital certificates
IT1399764B1 (it) * 2010-05-04 2013-05-03 F S I Fabbrica Italiana Sint Procedimento per la sintesi di 4h-imidazo [1,5-a][1,4]benzodiazepine, in particolare di midazolam.
CN103086986B (zh) * 2011-11-01 2015-11-04 上海医药工业研究院 1,4-苯二氮卓-n-亚硝胺类中间体的制备方法及其应用
CN103319486B (zh) * 2012-03-22 2017-10-10 徐州市心血管病研究所 合成4H‑咪唑并[1,5‑a][1,4]苯二氮卓,特别是咪达唑仑的方法
CN106032381A (zh) * 2015-03-16 2016-10-19 王志训 一种咪达唑仑衍生物的工业制造方法
CN106032380A (zh) * 2015-03-16 2016-10-19 王志训 一种咪达唑仑的工业制造方法
AU2017313753B2 (en) 2016-08-16 2022-01-27 The Trustees Of Columbia University In The City Of New York GABA(A) receptor modulators and methods to control airway hyperresponsiveness and inflammation in asthma

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307237A (en) * 1974-09-11 1981-12-22 Hoffmann-La Roche Inc. Imidazoles
US4440685A (en) * 1974-09-11 1984-04-03 Hoffmann-La Roche Inc. Imidazodiazepines and processes therefor
US4335042A (en) * 1980-04-21 1982-06-15 Hoffmann-La Roche Inc. Process to produce imidazobenzodiazepine intermediates

Also Published As

Publication number Publication date
CA2341524A1 (en) 2001-01-04
WO2001000625A1 (en) 2001-01-04
EP1199308A3 (en) 2002-05-02
EP1199308A2 (en) 2002-04-24
IL141394A0 (en) 2002-03-10
EP1105392A1 (en) 2001-06-13
HK1037617A1 (en) 2002-02-15
DK1105392T3 (da) 2002-12-30
US20010014738A1 (en) 2001-08-16
EP1105392B1 (en) 2002-09-04
JP2003503410A (ja) 2003-01-28
AU5874600A (en) 2001-01-31
CN1315953A (zh) 2001-10-03
ES2185599T3 (es) 2003-05-01
DE60000402D1 (de) 2002-10-10
KR20010079706A (ko) 2001-08-22
ATE223414T1 (de) 2002-09-15
DE60000402T2 (de) 2003-05-22

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