ES2171749T3 - Composiciones farmaceuticas que contienen inhibidores de la agregacion de plaquetas. - Google Patents
Composiciones farmaceuticas que contienen inhibidores de la agregacion de plaquetas.Info
- Publication number
- ES2171749T3 ES2171749T3 ES96940256T ES96940256T ES2171749T3 ES 2171749 T3 ES2171749 T3 ES 2171749T3 ES 96940256 T ES96940256 T ES 96940256T ES 96940256 T ES96940256 T ES 96940256T ES 2171749 T3 ES2171749 T3 ES 2171749T3
- Authority
- ES
- Spain
- Prior art keywords
- aggregation
- plates
- pharmaceutical compositions
- compositions containing
- containing inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000002776 aggregation Effects 0.000 title 1
- 238000004220 aggregation Methods 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 1
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4465—Non condensed piperidines, e.g. piperocaine only substituted in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
LA INVENCION ES UN COMPUESTO FARMACEUTICO PARA ADMINISTRACION INTRAVENOSA QUE CONSTA DE: A) UNA CANTIDAD FARMACEUTICAMENTE EFICAZ DE UN COMPUESTO DE FORMULA (I), POR EJEMPLO, EL ACIDO 2 S - (N - BUTILSULFONILAMINO) - 3 - [4 - ( - (PIPERIDIN 4 IL)BUTILOXI)FENIL]PROPIONICO; B) UNA CANTIDAD FARMACEUTICAMENTE ACEPTABLE DE UN TAMPON DE CITRATO EFICAZ PARA PROPORCIONAR UN PH APROXIMADO DE ENTRE 5 Y 7, Y C) UNA CANTIDAD FARMACEUTICAMENTE ACEPTABLE DE UN AGENTE AJUSTADOR DE LA TONICIDAD EFICAZ PARA QUE LA FORMULACION SEA ESENCIALMENTE ISOTONICA CON LA PRESION OSMOTICA DEL SISTEMA BIOLOGICO DEL PACIENTE.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US590795P | 1995-10-27 | 1995-10-27 | |
GBGB9603721.3A GB9603721D0 (en) | 1996-02-22 | 1996-02-22 | Composition for inhibiting platelet aggregation |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2171749T3 true ES2171749T3 (es) | 2002-09-16 |
Family
ID=26308777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96940256T Expired - Lifetime ES2171749T3 (es) | 1995-10-27 | 1996-10-23 | Composiciones farmaceuticas que contienen inhibidores de la agregacion de plaquetas. |
Country Status (35)
Country | Link |
---|---|
EP (1) | EP0859634B1 (es) |
JP (1) | JP3452367B2 (es) |
KR (1) | KR100362799B1 (es) |
CN (1) | CN1158107C (es) |
AT (1) | ATE213648T1 (es) |
AU (1) | AU712755B2 (es) |
BG (1) | BG63623B1 (es) |
BR (1) | BR9610878A (es) |
CA (1) | CA2234364C (es) |
CO (1) | CO4770960A1 (es) |
CY (1) | CY2292B1 (es) |
CZ (1) | CZ290381B6 (es) |
DE (1) | DE69619540T2 (es) |
DK (1) | DK0859634T3 (es) |
DZ (1) | DZ2110A1 (es) |
EA (1) | EA000628B1 (es) |
EE (1) | EE03518B1 (es) |
ES (1) | ES2171749T3 (es) |
HK (1) | HK1017846A1 (es) |
HU (1) | HU228757B1 (es) |
IL (1) | IL123790A (es) |
IS (1) | IS1948B (es) |
MX (1) | MX9803275A (es) |
MY (1) | MY116837A (es) |
NO (1) | NO324415B1 (es) |
NZ (1) | NZ323134A (es) |
PL (1) | PL185744B1 (es) |
PT (1) | PT859634E (es) |
SA (1) | SA96170527B1 (es) |
SI (1) | SI0859634T1 (es) |
SK (1) | SK282353B6 (es) |
TR (1) | TR199800716T2 (es) |
TW (1) | TW385248B (es) |
UA (1) | UA45423C2 (es) |
WO (1) | WO1997015328A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPQ633900A0 (en) | 2000-03-20 | 2000-04-15 | Jurox Pty Ltd | Anaesthetic composition |
CN1322863C (zh) * | 2004-10-29 | 2007-06-27 | 武汉远大制药集团股份有限公司 | 一种抑制血小板凝聚的注射液及其制备方法 |
CN100386079C (zh) * | 2005-03-24 | 2008-05-07 | 武汉远大制药集团股份有限公司 | 一种抑制血小板凝聚的注射用粉针及其制备方法 |
CN100367961C (zh) * | 2005-09-30 | 2008-02-13 | 天津南开允公医药科技有限公司 | 盐酸替罗非班冻干粉针注射剂及其制备方法 |
CN102125519B (zh) * | 2011-02-28 | 2012-07-11 | 正大青春宝药业有限公司 | 稳定的盐酸替罗非班注射液及其制备方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4931441A (en) * | 1988-11-09 | 1990-06-05 | Luitpold Pharmaceuticals, Inc. | Stabilized aqueous leucovorin calcium compositions |
NZ239846A (en) * | 1990-09-27 | 1994-11-25 | Merck & Co Inc | Sulphonamide derivatives and pharmaceutical compositions thereof |
-
1996
- 1996-10-17 TW TW085112709A patent/TW385248B/zh not_active IP Right Cessation
- 1996-10-22 MY MYPI96004366A patent/MY116837A/en unknown
- 1996-10-23 JP JP51683897A patent/JP3452367B2/ja not_active Expired - Fee Related
- 1996-10-23 PL PL96326419A patent/PL185744B1/pl not_active IP Right Cessation
- 1996-10-23 DE DE69619540T patent/DE69619540T2/de not_active Expired - Lifetime
- 1996-10-23 CZ CZ19981278A patent/CZ290381B6/cs not_active IP Right Cessation
- 1996-10-23 AT AT96940256T patent/ATE213648T1/de active
- 1996-10-23 PT PT96940256T patent/PT859634E/pt unknown
- 1996-10-23 CN CNB961978775A patent/CN1158107C/zh not_active Expired - Lifetime
- 1996-10-23 SK SK512-98A patent/SK282353B6/sk not_active IP Right Cessation
- 1996-10-23 KR KR10-1998-0702957A patent/KR100362799B1/ko not_active IP Right Cessation
- 1996-10-23 EP EP96940256A patent/EP0859634B1/en not_active Expired - Lifetime
- 1996-10-23 EE EE9800134A patent/EE03518B1/xx not_active IP Right Cessation
- 1996-10-23 NZ NZ323134A patent/NZ323134A/xx not_active IP Right Cessation
- 1996-10-23 WO PCT/US1996/017193 patent/WO1997015328A1/en active IP Right Grant
- 1996-10-23 DK DK96940256T patent/DK0859634T3/da active
- 1996-10-23 TR TR1998/00716T patent/TR199800716T2/xx unknown
- 1996-10-23 IL IL12379096A patent/IL123790A/en not_active IP Right Cessation
- 1996-10-23 EA EA199800336A patent/EA000628B1/ru not_active IP Right Cessation
- 1996-10-23 UA UA98042034A patent/UA45423C2/uk unknown
- 1996-10-23 ES ES96940256T patent/ES2171749T3/es not_active Expired - Lifetime
- 1996-10-23 SI SI9630443T patent/SI0859634T1/xx unknown
- 1996-10-23 AU AU77189/96A patent/AU712755B2/en not_active Ceased
- 1996-10-23 CA CA002234364A patent/CA2234364C/en not_active Expired - Fee Related
- 1996-10-23 BR BR9610878A patent/BR9610878A/pt not_active IP Right Cessation
- 1996-10-23 HU HU9902521A patent/HU228757B1/hu unknown
- 1996-10-24 CO CO96056416A patent/CO4770960A1/es unknown
- 1996-10-26 DZ DZ960154A patent/DZ2110A1/fr active
- 1996-12-25 SA SA96170527A patent/SA96170527B1/ar unknown
-
1998
- 1998-03-24 IS IS4699A patent/IS1948B/is unknown
- 1998-04-24 NO NO19981869A patent/NO324415B1/no not_active IP Right Cessation
- 1998-04-24 MX MX9803275A patent/MX9803275A/es unknown
- 1998-04-24 BG BG102405A patent/BG63623B1/bg unknown
-
1999
- 1999-05-17 HK HK99102186A patent/HK1017846A1/xx not_active IP Right Cessation
-
2002
- 2002-08-23 CY CY0200051A patent/CY2292B1/xx unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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