ES2076279T3 - Medicamentos que, como principio activo, contienen acidos carboxilicos con contenido en azufre, asi como su empleo para combatir retrovirus. - Google Patents

Medicamentos que, como principio activo, contienen acidos carboxilicos con contenido en azufre, asi como su empleo para combatir retrovirus.

Info

Publication number
ES2076279T3
ES2076279T3 ES90121339T ES90121339T ES2076279T3 ES 2076279 T3 ES2076279 T3 ES 2076279T3 ES 90121339 T ES90121339 T ES 90121339T ES 90121339 T ES90121339 T ES 90121339T ES 2076279 T3 ES2076279 T3 ES 2076279T3
Authority
ES
Spain
Prior art keywords
active substance
retroviruses
combat
drugs
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90121339T
Other languages
English (en)
Inventor
Joachim Prof Dr Kalden
Bernhard Prof Dr Fleckenstein
Andreas Dr Baur
Thomas Dr Harrer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asta Medica GmbH
Original Assignee
Asta Medica GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica GmbH filed Critical Asta Medica GmbH
Application granted granted Critical
Publication of ES2076279T3 publication Critical patent/ES2076279T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

MEDICAMENTO QUE CONTIENE, AL MENOS, UN COMPUESTO DE LA FORMULA I, SIENDO X UN ATOMO DE HIDROGENO O AMBAS X UN ENLACE SIMPLE ENTRE LOS DOS ATOMOS DE AZUFRE; Y ES HIDROGENO O ALQUILO C SUB 1 APEUTICAMENTE UTILIZABLES, EXCEPTUANDO ACIDO ALFALIPOMICO Y ACIDO DIHIDROLIPOMICO. EL MEDICAMENTO SE CARACTERIZA POR QUE LA UNIDAD DE DOSIFICACION PARA PREPARADOS SOLIDOS Y/O SEMISOLIDOS CONTIENE DE 20 MG A 6G, ESPECIALMENTE DE 50 MG A 2G, PREFERENTEMENTE DE 100 MG A 1 G, DE LA SUSTANCIA ACTIVA I, O POR QUE SE TRATA DE SOLUCIONES, SUSPENSIONES Y/O EMULSIONES QUE CONTIENEN DE 0,2 MG A 800 MG POR ML, PREFERENTEMENTE DE 10 MG A 500 MG, ESPECIALMENTE DE 40 MG A 200 MG POR ML, DE SUSTANCIA ACTIVA O DE UNA DE SUS SALES FARMACEUTICAMENTE UTILIZABLES. PROCEDIMIENTO PARA SU FABRICACION.
ES90121339T 1989-11-09 1990-11-08 Medicamentos que, como principio activo, contienen acidos carboxilicos con contenido en azufre, asi como su empleo para combatir retrovirus. Expired - Lifetime ES2076279T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3937325 1989-11-09
DE4015728 1990-05-16

Publications (1)

Publication Number Publication Date
ES2076279T3 true ES2076279T3 (es) 1995-11-01

Family

ID=25886910

Family Applications (2)

Application Number Title Priority Date Filing Date
ES90121339T Expired - Lifetime ES2076279T3 (es) 1989-11-09 1990-11-08 Medicamentos que, como principio activo, contienen acidos carboxilicos con contenido en azufre, asi como su empleo para combatir retrovirus.
ES9002846A Expired - Lifetime ES2029769A6 (es) 1989-11-09 1990-11-08 Procedimiento para preparar medicamentos a base de acidos carboxilicos que contienen azufre como sustancia activa.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES9002846A Expired - Lifetime ES2029769A6 (es) 1989-11-09 1990-11-08 Procedimiento para preparar medicamentos a base de acidos carboxilicos que contienen azufre como sustancia activa.

Country Status (19)

Country Link
US (1) US5334612A (es)
EP (1) EP0427246B1 (es)
JP (1) JPH03188021A (es)
AT (2) AT500684B8 (es)
BE (2) BE1003834A5 (es)
CA (1) CA2029599C (es)
CH (1) CH684054A5 (es)
DE (3) DE4035456A1 (es)
DK (3) DK173585B1 (es)
ES (2) ES2076279T3 (es)
FR (1) FR2653997B1 (es)
GB (1) GB2239797B (es)
GR (3) GR1000918B (es)
IE (1) IE67874B1 (es)
IT (1) IT1246328B (es)
LU (1) LU87834A1 (es)
NL (1) NL9002438A (es)
PT (1) PT95827B (es)
SE (1) SE508601C2 (es)

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DE4320117A1 (de) * 1992-01-18 1994-12-22 Margarethe Rabien Kombinatinspräparate
DE4201196C2 (de) * 1992-01-18 1997-05-15 Rabien Margarethe Arzneimittel zur Behandlung der Polyneuropathie
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DE9213914U1 (de) * 1992-10-15 1992-12-03 Asta Medica AG, 6000 Frankfurt Ampulle und Infusionslösung von Thioctsäure in Form der wasserlöslichen Salze der Thioctsäure
WO1994022438A1 (en) * 1993-03-26 1994-10-13 Constantin Romulus Dinu Pharmaceutical composition for the treatment of certain viruses and autoimmune diseases and the procedure of its preparation
DE4345199C2 (de) * 1993-05-22 1995-10-12 Asta Medica Ag Verwendung von Dihydroliponsäure zur Unterdrückung von Unverträglichkeitsreaktionen im Grenzbereich von Implantaten mit lebendem Körpergewebe
DE4317173C2 (de) * 1993-05-22 1995-06-14 Asta Medica Ag Verwendung von Dihydroliponsäure als Ophthalmologicum
DE4338508A1 (de) * 1993-11-11 1995-05-18 Asta Medica Ag Arzneimittelzubereitungen enthaltend Thioctsäure oder Dihydroliponsäure in Form von Einschlußverbindungen mit Cyclodextrinen oder Cyclodextrinderivaten und in Form von Granulaten, Kau- oder Brausetabletten
US5463093A (en) * 1993-11-26 1995-10-31 Garnett; Merrill Palladium complexes and methods for using same in the treatment of tumors or Psoriasis
DE4433764A1 (de) * 1994-09-22 1996-03-28 Asta Medica Ag Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit
DE4439480C1 (de) * 1994-11-08 1996-06-05 Asta Medica Ag Verwendung von D,L- alpha-Liponsäure und/oder ihren Enantiomeren, und/oder ihren Derivaten als Zusatz bei Erythrozyten-Flüssigkonserven für homologe und autologe Erythrozyten-Konzentrate und als Zusatz bei Erythrozyten-Kryokonserven für homologe und autologe Erythrozytenkonzentrate
DE69734734D1 (de) * 1996-07-05 2005-12-29 Us Gov Health & Human Serv Gesättigte 1,2-dithiaheterocyclische verbindungen enthaltende antivirale pharmazeutische zubereitungen
WO1998023606A1 (fr) * 1996-11-27 1998-06-04 Fuji Kagaku Kogyo Kabushiki Kaisha Derives dithio cycliques, remedes contre des maladies renales diabetiques, agents hypoglycemiques, agents hypolipidemiques et agents lenitifs contre les troubles digestifs
US6090842A (en) 1998-03-10 2000-07-18 The Regents Of The University Of California Lipoic acid analogs
US6905707B2 (en) * 1998-05-28 2005-06-14 Medical Research Institute Controlled release arginine alpha ketoglutarate
US6197340B1 (en) * 1998-05-28 2001-03-06 Medical Research Institute Controlled release lipoic acid
US6191162B1 (en) 1998-05-28 2001-02-20 Medical Research Institute Method of reducing serum glucose levels
US20050085498A1 (en) * 1998-05-28 2005-04-21 Byrd Edward A. Oral formulation of lipid soluble thiamine, lipoic acid, creatine derivative, and L-arginine alpha-ketoglutarate
US20040259895A1 (en) * 1998-05-28 2004-12-23 Medical Research Institute Oral formulation of lipid soluble thiamine and lipoic acid
US6136339A (en) * 1998-08-21 2000-10-24 Gardiner; Paul T. Food supplements and methods comprising lipoic acid and creatine
AU775388B2 (en) * 1998-11-25 2004-07-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Scavenger compounds
US6573299B1 (en) 1999-09-20 2003-06-03 Advanced Medical Instruments Method and compositions for treatment of the aging eye
CN1232252C (zh) * 1999-10-01 2005-12-21 Skw特罗斯特贝格股份公司 包含α－硫辛酸(衍生物)的延时释放剂型
DE10045904B4 (de) * 1999-10-01 2007-07-12 Degussa Gmbh alpha-Liponsäure(-Derivate) enthaltende Retardform
US6664287B2 (en) * 2000-03-15 2003-12-16 Bethesda Pharmaceuticals, Inc. Antioxidants
ES2259034T3 (es) * 2000-06-06 2006-09-16 Basf Aktiengesellschaft Uso de un enantiomero del acido lipoico en cosmeticos y dermatologicos.
DE10027968A1 (de) * 2000-06-08 2001-12-13 Asta Medica Ag Mittel zur Therapie von Demenzen
US6683110B1 (en) 2001-05-23 2004-01-27 University Of Central Florida Methyl esters of substituted 4-oxo-2-butenoic acid for treatment of tuberculosis
US6649610B1 (en) 2001-05-23 2003-11-18 University Of Central Florida 2-oxo-1, 4-benzoxazine compounds for treatment of tuberculosis
US6852876B1 (en) 2001-06-08 2005-02-08 University Of Central Florida Treatment of colon cancer
US6602907B1 (en) 2001-06-08 2003-08-05 University Of Central Florida Treatment of breast cancer
US6686496B1 (en) 2001-06-08 2004-02-03 University Of Central Florida Treatment of myeloma
EP1476440A4 (en) * 2002-02-22 2005-06-01 Albany College Of Pharmacy METHODS AND COMPOUNDS USEFUL IN INHIBITION BY RADICAL AND / OR OXIDIZING AGGRESSION AND IN THE TREATMENT AND PREVENTION OF DISEASE
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US20040133938A1 (en) * 2002-11-19 2004-07-08 Yinghui Dan Use of lipoic acid in plant culture media
DE10318045A1 (de) * 2003-04-17 2004-11-04 Basf Ag Stabile Ammoniumsalze der alpha-Liponsäure, ihre Herstellung und Verwendung
JP4716666B2 (ja) * 2003-05-21 2011-07-06 有限会社オガ リサーチ α−リポ酸含有水性製剤
CN100422134C (zh) * 2004-03-12 2008-10-01 北京天衡药物研究院 新的2-（α-正戊酮基）苯甲酸盐及其制法和用途
US20060213815A1 (en) * 2005-01-28 2006-09-28 Wille John J Hydrocarbon fume suppression by higher vapor pressure temperature oils
WO2006134609A2 (en) * 2005-06-16 2006-12-21 Mmi Corporation Novel anticancer agent, methods for obtaining the same and pharmaceutical compositions thereof
JP2009525289A (ja) * 2006-01-31 2009-07-09 パルスロース カンパニー 免疫調節特性を有する薬草抽出物
US7282225B1 (en) 2006-09-27 2007-10-16 Occular Technologies, Inc. Composition and methods for improving retinal health
EA200901011A1 (ru) * 2009-06-08 2010-12-30 Общество С Ограниченной Ответственностью "Научно-Производственный Центр Белагроген" Препарат на основе интерферона
ES2883956T3 (es) * 2015-05-21 2021-12-09 Ophtalmis Composición oftálmica que comprende ácido lipoico y ácido hialurónico

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JPH10203336A (ja) * 1997-01-17 1998-08-04 Aisin Seiki Co Ltd アンチスキッド制御装置

Also Published As

Publication number Publication date
DK0427246T3 (da) 1995-11-27
EP0427246B1 (de) 1995-08-09
IE904035A1 (en) 1991-05-22
CA2029599C (en) 1998-08-11
CH684054A5 (de) 1994-07-15
IE67874B1 (en) 1996-05-01
AT500684A1 (de) 2006-02-15
SE9003564D0 (sv) 1990-11-08
IT9048456A0 (it) 1990-11-08
LU87834A1 (de) 1991-05-07
GB2239797A (en) 1991-07-17
DK200001239A (da) 2000-08-22
SE508601C2 (sv) 1998-10-19
GR3017695T3 (en) 1996-01-31
EP0427246A3 (en) 1992-06-03
PT95827B (pt) 1997-11-28
DE59009497D1 (de) 1995-09-14
DE9017987U1 (de) 1993-12-09
DE4035456A1 (de) 1991-05-16
DK267790D0 (da) 1990-11-08
AT500684B8 (de) 2006-11-15
DK173752B1 (da) 2001-09-10
PT95827A (pt) 1991-09-13
IT9048456A1 (it) 1992-05-08
GB9024252D0 (en) 1990-12-19
FR2653997B1 (fr) 1995-01-20
JPH03188021A (ja) 1991-08-16
GR1001503B (el) 1994-02-28
CA2029599A1 (en) 1991-05-10
IT1246328B (it) 1994-11-17
GR900100796A (en) 1992-04-17
GB2239797B (en) 1994-06-15
AT500684B1 (de) 2006-10-15
FR2653997A1 (fr) 1991-05-10
GR1000918B (el) 1993-03-16
US5334612A (en) 1994-08-02
DK173585B1 (da) 2001-04-02
SE9003564L (sv) 1991-06-07
ATE126053T1 (de) 1995-08-15
BE1003834A5 (fr) 1992-06-23
DK267790A (da) 1991-05-10
NL9002438A (nl) 1991-06-03
ES2029769A6 (es) 1992-09-01
BE1005018A3 (fr) 1993-03-23
EP0427246A2 (de) 1991-05-15

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