ES2115589T3 - Medicamento que contiene acido r-alfa-liponico o acido s-alfa-liponico como sustancia activa. - Google Patents

Medicamento que contiene acido r-alfa-liponico o acido s-alfa-liponico como sustancia activa.

Info

Publication number
ES2115589T3
ES2115589T3 ES90121340T ES90121340T ES2115589T3 ES 2115589 T3 ES2115589 T3 ES 2115589T3 ES 90121340 T ES90121340 T ES 90121340T ES 90121340 T ES90121340 T ES 90121340T ES 2115589 T3 ES2115589 T3 ES 2115589T3
Authority
ES
Spain
Prior art keywords
alpha
liponic acid
active substance
medication containing
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90121340T
Other languages
English (en)
Inventor
Heinz Dr Ulrich
Carl-Heinrich Dr Weischer
Jurgen Dr Engel
Helmut Dr Hettche
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asta Medica GmbH
Original Assignee
Asta Medica GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica GmbH filed Critical Asta Medica GmbH
Application granted granted Critical
Publication of ES2115589T3 publication Critical patent/ES2115589T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

MEDICAMENTO Y PROCEDIMIENTO PARA SU FABRICACION QUE CONTIENE ACIDO R-ALFA-LIPOMICO O ACIDO S-ALFA-LIPOMICO O SUS SALES FARMACEUTICAMENTE UTILIZABLES. LOS MEDICAMENTOS POSEEN UN EFECTO CITOPROTECTOR Y SON APTOS PARA SU USO COMO ANALGESICOS Y ANTIINFLAMATORIOS.
ES90121340T 1989-11-09 1990-11-08 Medicamento que contiene acido r-alfa-liponico o acido s-alfa-liponico como sustancia activa. Expired - Lifetime ES2115589T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3937323 1989-11-09

Publications (1)

Publication Number Publication Date
ES2115589T3 true ES2115589T3 (es) 1998-07-01

Family

ID=6393200

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90121340T Expired - Lifetime ES2115589T3 (es) 1989-11-09 1990-11-08 Medicamento que contiene acido r-alfa-liponico o acido s-alfa-liponico como sustancia activa.

Country Status (10)

Country Link
US (2) US5728735A (es)
EP (2) EP0812590A3 (es)
JP (1) JPH03169813A (es)
AT (1) ATE163849T1 (es)
CA (1) CA2029596C (es)
DE (2) DE4035442B4 (es)
DK (1) DK0427247T3 (es)
ES (1) ES2115589T3 (es)
IE (1) IE904034A1 (es)
PT (1) PT95826B (es)

Families Citing this family (96)

* Cited by examiner, † Cited by third party
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DE9213914U1 (de) * 1992-10-15 1992-12-03 Asta Medica AG, 6000 Frankfurt Ampulle und Infusionslösung von Thioctsäure in Form der wasserlöslichen Salze der Thioctsäure
DE4235912C2 (de) * 1992-10-23 2002-12-05 Viatris Gmbh Verfahren zur Herstellung kristalliner Thioctsäure und deren Verwendung
DE4317646A1 (de) * 1993-05-27 1994-12-01 Asta Medica Ag Tabletten mit Thioctsäure und mindestens einer basischen Komponente
DE4327462A1 (de) * 1993-08-16 1995-02-23 Carl Heinrich Dr Weischer Neue N-Acetyl-p-Aminophenol-Derivate zur Bekämpfung von Schmerzzuständen
DE4338508A1 (de) * 1993-11-11 1995-05-18 Asta Medica Ag Arzneimittelzubereitungen enthaltend Thioctsäure oder Dihydroliponsäure in Form von Einschlußverbindungen mit Cyclodextrinen oder Cyclodextrinderivaten und in Form von Granulaten, Kau- oder Brausetabletten
DE4427079C2 (de) * 1994-07-30 2002-12-19 Viatris Gmbh Verfahren zur Racemisierung von Enantiomeren der alpha-Liponsäure
DE4433764A1 (de) 1994-09-22 1996-03-28 Asta Medica Ag Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit
DE4439480C1 (de) * 1994-11-08 1996-06-05 Asta Medica Ag Verwendung von D,L- alpha-Liponsäure und/oder ihren Enantiomeren, und/oder ihren Derivaten als Zusatz bei Erythrozyten-Flüssigkonserven für homologe und autologe Erythrozyten-Konzentrate und als Zusatz bei Erythrozyten-Kryokonserven für homologe und autologe Erythrozytenkonzentrate
DE19510130C1 (de) * 1995-03-21 1996-11-21 Asta Medica Ag Verfahren zur Herstellung rieselfähiger R,S-Thioctsäure, R,S-Thioctsäure sowie deren Verwendung
DE19533882A1 (de) 1995-09-13 1997-03-20 Dresden Arzneimittel Herstellung und Verwendung der reinen Enantiomere der 8-Halogen-6-hydroxyoctansäuren, ihrer Alkylester und ihrer Salze mit reinen Enantiomeren des alpha-Methylbenzylamins
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US6365623B1 (en) 1997-11-17 2002-04-02 Nicholas V. Perricone Treatment of acne using lipoic acid
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US20050085498A1 (en) * 1998-05-28 2005-04-21 Byrd Edward A. Oral formulation of lipid soluble thiamine, lipoic acid, creatine derivative, and L-arginine alpha-ketoglutarate
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US6191162B1 (en) 1998-05-28 2001-02-20 Medical Research Institute Method of reducing serum glucose levels
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US6573299B1 (en) 1999-09-20 2003-06-03 Advanced Medical Instruments Method and compositions for treatment of the aging eye
US6479069B1 (en) * 1999-09-23 2002-11-12 Juvenon, Inc. Nutritional supplement for increased energy and stamina
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Also Published As

Publication number Publication date
PT95826A (pt) 1991-09-13
US6271254B1 (en) 2001-08-07
EP0427247A3 (en) 1992-01-02
ATE163849T1 (de) 1998-03-15
PT95826B (pt) 1997-11-28
CA2029596C (en) 2000-05-23
EP0427247A2 (de) 1991-05-15
DE4035442A1 (de) 1991-05-16
DE59010810D1 (de) 1998-04-16
US5728735A (en) 1998-03-17
CA2029596A1 (en) 1991-05-10
EP0427247B1 (de) 1998-03-11
IE904034A1 (en) 1991-05-22
EP0812590A3 (de) 1999-06-09
JPH03169813A (ja) 1991-07-23
DK0427247T3 (da) 1998-09-28
EP0812590A2 (de) 1997-12-17
DE4035442B4 (de) 2010-04-29

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