ES2071334T3 - Analogos de anillos fusionados de nitrogeno conteniendo heterociclos no aromaticos. - Google Patents
Analogos de anillos fusionados de nitrogeno conteniendo heterociclos no aromaticos.Info
- Publication number
- ES2071334T3 ES2071334T3 ES91918058T ES91918058T ES2071334T3 ES 2071334 T3 ES2071334 T3 ES 2071334T3 ES 91918058 T ES91918058 T ES 91918058T ES 91918058 T ES91918058 T ES 91918058T ES 2071334 T3 ES2071334 T3 ES 2071334T3
- Authority
- ES
- Spain
- Prior art keywords
- analogs
- containing non
- rings containing
- aromatic hetero
- fused nitrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Eye Examination Apparatus (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Electroluminescent Light Sources (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59042390A | 1990-09-28 | 1990-09-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2071334T3 true ES2071334T3 (es) | 1995-06-16 |
Family
ID=24362216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91918058T Expired - Lifetime ES2071334T3 (es) | 1990-09-28 | 1991-08-20 | Analogos de anillos fusionados de nitrogeno conteniendo heterociclos no aromaticos. |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0550635B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JPH0772175B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN1060285A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE121389T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU651145B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR9106905A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2089736A1 (cg-RX-API-DMAC7.html) |
| CZ (1) | CZ387492A3 (cg-RX-API-DMAC7.html) |
| DE (1) | DE69109125T2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK0550635T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2071334T3 (cg-RX-API-DMAC7.html) |
| FI (1) | FI931370A7 (cg-RX-API-DMAC7.html) |
| HU (1) | HUT68667A (cg-RX-API-DMAC7.html) |
| IE (1) | IE66042B1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL99525A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX9101274A (cg-RX-API-DMAC7.html) |
| NO (1) | NO931151D0 (cg-RX-API-DMAC7.html) |
| PT (1) | PT99064A (cg-RX-API-DMAC7.html) |
| TW (1) | TW199144B (cg-RX-API-DMAC7.html) |
| WO (1) | WO1992006079A1 (cg-RX-API-DMAC7.html) |
| YU (1) | YU159291A (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA917744B (cg-RX-API-DMAC7.html) |
Families Citing this family (85)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5716965A (en) * | 1991-05-22 | 1998-02-10 | Pfizer Inc. | Substituted 3-aminoquinuclidines |
| AU657967B2 (en) * | 1991-06-20 | 1995-03-30 | Pfizer Inc. | Fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles |
| TW202432B (cg-RX-API-DMAC7.html) * | 1991-06-21 | 1993-03-21 | Pfizer | |
| MY110227A (en) * | 1991-08-12 | 1998-03-31 | Ciba Geigy Ag | 1-acylpiperindine compounds. |
| EP0919245A3 (en) * | 1991-09-20 | 2000-11-15 | Glaxo Group Limited | NK-1 receptor antagonist and a systemic antiinflammatory corticosteroid for the treatment of emesis |
| DK0613458T3 (da) * | 1991-11-12 | 1998-02-09 | Pfizer | Acykliske ethylendiaminderivater som substans P receptorantagonister |
| EP0641328B1 (en) * | 1992-05-18 | 2001-11-21 | Pfizer Inc. | Bridged aza-bicyclic derivatives as substance p antagonists |
| US5637699A (en) * | 1992-06-29 | 1997-06-10 | Merck & Co., Inc. | Process for preparing morpholine tachykinin receptor antagonists |
| US6048859A (en) | 1992-06-29 | 2000-04-11 | Merck & Co., Inc. | Morpholine and thiomorpholine tachykinin receptor antagonists |
| US5719147A (en) * | 1992-06-29 | 1998-02-17 | Merck & Co., Inc. | Morpholine and thiomorpholine tachykinin receptor antagonists |
| AU4396193A (en) * | 1992-08-04 | 1994-03-03 | Pfizer Inc. | 3-benzylamino-2-phenyl-piperidine derivatives as substance p receptor antagonists |
| GB9216911D0 (en) * | 1992-08-10 | 1992-09-23 | Merck Sharp & Dohme | Therapeutic agents |
| JP2909214B2 (ja) * | 1992-08-19 | 1999-06-23 | フアイザー・インコーポレイテツド | 置換ベンジルアミノ窒素含有非芳香族複素環化合物 |
| US5387595A (en) * | 1992-08-26 | 1995-02-07 | Merck & Co., Inc. | Alicyclic compounds as tachykinin receptor antagonists |
| US5344830A (en) * | 1992-12-10 | 1994-09-06 | Merck & Co., Inc. | N,N-diacylpiperazine tachykinin antagonists |
| JP2722279B2 (ja) * | 1992-12-10 | 1998-03-04 | ファイザー・インク. | アミノメチレンで置換した非芳香族複素環式化合物及びサブスタンスpのアンタゴニストとしての使用 |
| US5830854A (en) * | 1992-12-14 | 1998-11-03 | Merck Sharp & Dohme, Limited | Method of treating cystic fibrosis using a tachykinin receptor antagonist |
| US5340826A (en) * | 1993-02-04 | 1994-08-23 | Pfizer Inc. | Pharmaceutical agents for treatment of urinary incontinence |
| US5393762A (en) * | 1993-06-04 | 1995-02-28 | Pfizer Inc. | Pharmaceutical agents for treatment of emesis |
| US5854262A (en) * | 1993-10-07 | 1998-12-29 | Pfizer Inc. | Aminomethylene substituted non-aromatic heterocycles and use as substance P antagonists |
| US5610165A (en) * | 1994-02-17 | 1997-03-11 | Merck & Co., Inc. | N-acylpiperidine tachykinin antagonists |
| IL112778A0 (en) * | 1994-03-04 | 1995-05-26 | Merck & Co Inc | Substituted heterocycles, their preparation and pharmaceutical compositions containing them |
| TW397825B (en) * | 1994-10-14 | 2000-07-11 | Novartis Ag | Aroyl-piperidine derivatives |
| FR2725900B1 (fr) * | 1994-10-21 | 1997-07-18 | Sanofi Sa | Utilisation d'antagonistes des recepteurs nk1 pour la preparation de medicaments a action cardioregulatrice |
| TW458774B (en) | 1995-10-20 | 2001-10-11 | Pfizer | Antiemetic pharmaceutical compositions |
| CA2251368A1 (en) * | 1997-02-14 | 1998-08-20 | Bayer Corporation | Amide derivatives as selective neuropeptide y receptor antagonists |
| US6245817B1 (en) | 1997-02-14 | 2001-06-12 | Bayer Corporation | NPY5 receptor antagonists and methods for using same |
| US6048900A (en) * | 1998-02-13 | 2000-04-11 | Bayer Corporation | Amide derivatives and methods for using the same as selective neuropeptide Y receptor antagonists |
| CA2251580A1 (en) * | 1997-02-14 | 1998-08-20 | Bayer Corporation | Amides as npy5 receptor antagonists |
| CN1414953A (zh) | 1999-11-03 | 2003-04-30 | 阿尔巴尼分子研究公司 | 芳基和杂芳基取代的四氢异喹啉及其阻断去甲肾上腺素、多巴胺和5-羟色胺重摄取的用途 |
| US7163949B1 (en) | 1999-11-03 | 2007-01-16 | Amr Technology, Inc. | 4-phenyl substituted tetrahydroisoquinolines and use thereof |
| US7119207B2 (en) | 2000-04-10 | 2006-10-10 | Pfizer Inc | Benzoamide piperidine containing compounds and related compounds |
| JP4001486B2 (ja) * | 2000-04-10 | 2007-10-31 | ファイザー・プロダクツ・インク | ベンゾアミドピペリジン含有化合物及び関連化合物 |
| CA2415532C (en) | 2000-07-11 | 2010-05-11 | Albany Molecular Research, Inc. | Novel 4-phenyl substituted tetrahydroisoquinolines therapeutic use thereof |
| AU2002211621A1 (en) * | 2000-10-10 | 2002-04-22 | Calyx Therapeutics, Inc. | Tricyclic compounds and uses thereof |
| CN101119969B (zh) | 2004-07-15 | 2014-04-09 | 阿尔巴尼分子研究公司 | 芳基和杂芳基取代的四氢异喹啉及其阻断去甲肾上腺素、多巴胺和血清素的重摄取的应用 |
| ATE550019T1 (de) | 2005-05-17 | 2012-04-15 | Merck Sharp & Dohme | Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs |
| DE102005027168A1 (de) * | 2005-06-13 | 2006-12-14 | Merck Patent Gmbh | Tetrahydrochinoline |
| US7956050B2 (en) | 2005-07-15 | 2011-06-07 | Albany Molecular Research, Inc. | Aryl- and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
| AU2006297443B2 (en) | 2005-09-29 | 2010-08-12 | Merck Sharp & Dohme Corp. | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators |
| GB0603041D0 (en) | 2006-02-15 | 2006-03-29 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
| GB0617867D0 (en) * | 2006-09-11 | 2006-10-18 | Glaxo Group Ltd | Chemical compounds |
| CA2770486C (en) | 2006-09-22 | 2014-07-15 | Merck Sharp & Dohme Corp. | Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer |
| US20110218176A1 (en) | 2006-11-01 | 2011-09-08 | Barbara Brooke Jennings-Spring | Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development |
| PL2805945T3 (pl) | 2007-01-10 | 2019-09-30 | Msd Italia S.R.L. | Indazole podstawione grupą amidową jako inhibitory polimerazy poli(adp-rybozy) - (parp) |
| CN101641099A (zh) | 2007-01-24 | 2010-02-03 | 葛兰素集团有限公司 | 包含3,5-二氨基-6-(2,3-二氯苯基)-1,2,4-三嗪或r(-)-2,4-二氨基-5-(2,3-二氯苯基)-6-氟甲基嘧啶和nk1的药物组合物 |
| JP5319518B2 (ja) | 2007-04-02 | 2013-10-16 | Msd株式会社 | インドールジオン誘導体 |
| WO2009002495A1 (en) | 2007-06-27 | 2008-12-31 | Merck & Co., Inc. | 4-carboxybenzylamino derivatives as histone deacetylase inhibitors |
| GB0716573D0 (en) * | 2007-08-24 | 2007-10-03 | Glaxo Group Ltd | Chemical compounds |
| KR20100126467A (ko) | 2008-03-03 | 2010-12-01 | 타이거 파마테크 | 티로신 키나아제 억제제 |
| GB0804326D0 (en) * | 2008-03-07 | 2008-04-16 | Glaxo Group Ltd | Novel compounds |
| US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
| AR071997A1 (es) | 2008-06-04 | 2010-07-28 | Bristol Myers Squibb Co | Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina |
| UA105182C2 (ru) | 2008-07-03 | 2014-04-25 | Ньюрексон, Інк. | Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность |
| EP2413932A4 (en) | 2009-04-01 | 2012-09-19 | Merck Sharp & Dohme | HAMMER OF ACT ACTIVITY |
| JP2012526823A (ja) | 2009-05-12 | 2012-11-01 | アルバニー モレキュラー リサーチ, インコーポレイテッド | アリール、ヘテロアリール、および複素環置換テトラヒドロイソキノリンならびにそれらの使用 |
| JP5764553B2 (ja) | 2009-05-12 | 2015-08-19 | アルバニー モレキュラー リサーチ, インコーポレイテッド | 7−([1,2,4]トリアゾロ[1,5−a]ピリジン−6−イル)−4−(3,4−ジクロロフェニル)−1,2,3,4−テトラヒドロイソキノリンおよびその使用 |
| JP5739415B2 (ja) | 2009-05-12 | 2015-06-24 | ブリストル−マイヤーズ スクウィブ カンパニー | (S)−7−([1,2,4]トリアゾロ[1,5−a]ピリジン−6−イル)−4−(3,4−ジクロロフェニル)−1,2,3,4−テトラヒドロイソキノリンの結晶形態およびその使用 |
| EP2488028B1 (en) | 2009-10-14 | 2020-08-19 | Merck Sharp & Dohme Corp. | Substituted piperidines that increase p53 activity and the uses thereof |
| EP2584903B1 (en) | 2010-06-24 | 2018-10-24 | Merck Sharp & Dohme Corp. | Novel heterocyclic compounds as erk inhibitors |
| WO2012018754A2 (en) | 2010-08-02 | 2012-02-09 | Merck Sharp & Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF CATENIN (CADHERIN-ASSOCIATED PROTEIN), BETA 1 (CTNNB1) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
| HUE044815T2 (hu) | 2010-08-17 | 2019-11-28 | Sirna Therapeutics Inc | Hepatitisz B vírus (HBV) génexpressziójának RNS-interferencia közvetített gátlása, rövid interferáló nukleinsav (SINS) alkalmazásával |
| US8883801B2 (en) | 2010-08-23 | 2014-11-11 | Merck Sharp & Dohme Corp. | Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors |
| US8946216B2 (en) | 2010-09-01 | 2015-02-03 | Merck Sharp & Dohme Corp. | Indazole derivatives useful as ERK inhibitors |
| US9242981B2 (en) | 2010-09-16 | 2016-01-26 | Merck Sharp & Dohme Corp. | Fused pyrazole derivatives as novel ERK inhibitors |
| US9260471B2 (en) | 2010-10-29 | 2016-02-16 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA) |
| EP2654748B1 (en) | 2010-12-21 | 2016-07-27 | Merck Sharp & Dohme Corp. | Indazole derivatives useful as erk inhibitors |
| EP2699568A1 (en) | 2011-04-21 | 2014-02-26 | Piramal Enterprises Limited | A crystalline form of a salt of a morpholino sulfonyl indole derivative and a process for its preparation |
| EP2770987B1 (en) | 2011-10-27 | 2018-04-04 | Merck Sharp & Dohme Corp. | Novel compounds that are erk inhibitors |
| WO2013165816A2 (en) | 2012-05-02 | 2013-11-07 | Merck Sharp & Dohme Corp. | SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS |
| RU2660429C2 (ru) | 2012-09-28 | 2018-07-06 | Мерк Шарп И Доум Корп. | Новые соединения, которые являются ингибиторами erk |
| US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| PL2925888T3 (pl) | 2012-11-28 | 2018-03-30 | Merck Sharp & Dohme Corp. | Kompozycje i sposoby do stosowania w leczeniu nowotworów |
| RU2690663C2 (ru) | 2012-12-20 | 2019-06-05 | Мерк Шарп И Доум Корп. | Замещенные имидазопиридины в качестве ингибиторов hdm2 |
| US9540377B2 (en) | 2013-01-30 | 2017-01-10 | Merck Sharp & Dohme Corp. | 2,6,7,8 substituted purines as HDM2 inhibitors |
| EP3041938A1 (en) | 2013-09-03 | 2016-07-13 | Moderna Therapeutics, Inc. | Circular polynucleotides |
| CN104610146A (zh) * | 2015-01-23 | 2015-05-13 | 常州大学 | 一种3-氮杂二环[5,1,0]-7-醛及合成方法 |
| CN105330588B (zh) * | 2015-10-16 | 2017-09-26 | 辽宁中医药大学 | 马齿苋中生物碱Oleracone及其提取分离方法 |
| WO2018071283A1 (en) | 2016-10-12 | 2018-04-19 | Merck Sharp & Dohme Corp. | Kdm5 inhibitors |
| WO2019094312A1 (en) | 2017-11-08 | 2019-05-16 | Merck Sharp & Dohme Corp. | Prmt5 inhibitors |
| US10947234B2 (en) | 2017-11-08 | 2021-03-16 | Merck Sharp & Dohme Corp. | PRMT5 inhibitors |
| AU2019317549A1 (en) | 2018-08-07 | 2021-02-25 | Msd International Gmbh | PRMT5 inhibitors |
| WO2020033282A1 (en) | 2018-08-07 | 2020-02-13 | Merck Sharp & Dohme Corp. | Prmt5 inhibitors |
| EP3833667B1 (en) | 2018-08-07 | 2024-03-13 | Merck Sharp & Dohme LLC | Prmt5 inhibitors |
| CN113121427B (zh) * | 2021-03-19 | 2022-04-01 | 广东工业大学 | 一种喹啉类衍生物及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3452026A (en) * | 1966-03-15 | 1969-06-24 | Bristol Myers Co | Substituted 1,2,3,4-tetrahydroquinolines |
| FR1555552A (cg-RX-API-DMAC7.html) * | 1967-07-05 | 1969-01-31 | ||
| US4198415A (en) * | 1979-01-22 | 1980-04-15 | Eli Lilly And Company | Prolactin inhibiting octahydro pyrazolo[3,4-g]quinolines |
| MX18467A (es) * | 1988-11-23 | 1993-07-01 | Pfizer | Agentes terapeuticos de quinuclidinas |
-
1991
- 1991-08-20 BR BR919106905A patent/BR9106905A/pt not_active Application Discontinuation
- 1991-08-20 EP EP91918058A patent/EP0550635B1/en not_active Expired - Lifetime
- 1991-08-20 WO PCT/US1991/005776 patent/WO1992006079A1/en not_active Ceased
- 1991-08-20 FI FI931370A patent/FI931370A7/fi not_active Application Discontinuation
- 1991-08-20 AU AU87463/91A patent/AU651145B2/en not_active Expired - Fee Related
- 1991-08-20 DE DE69109125T patent/DE69109125T2/de not_active Expired - Fee Related
- 1991-08-20 CA CA002089736A patent/CA2089736A1/en not_active Abandoned
- 1991-08-20 AT AT91918058T patent/ATE121389T1/de not_active IP Right Cessation
- 1991-08-20 DK DK91918058.8T patent/DK0550635T3/da active
- 1991-08-20 JP JP3517076A patent/JPH0772175B2/ja not_active Expired - Fee Related
- 1991-08-20 ES ES91918058T patent/ES2071334T3/es not_active Expired - Lifetime
- 1991-08-20 HU HU9300898A patent/HUT68667A/hu unknown
- 1991-08-20 CZ CS923874A patent/CZ387492A3/cs unknown
- 1991-08-23 TW TW080106710A patent/TW199144B/zh active
- 1991-09-19 IL IL99525A patent/IL99525A0/xx unknown
- 1991-09-26 MX MX9101274A patent/MX9101274A/es unknown
- 1991-09-26 PT PT99064A patent/PT99064A/pt not_active Application Discontinuation
- 1991-09-27 CN CN91109446A patent/CN1060285A/zh active Pending
- 1991-09-27 ZA ZA917744A patent/ZA917744B/xx unknown
- 1991-09-27 IE IE339691A patent/IE66042B1/en not_active IP Right Cessation
- 1991-09-27 YU YU159291A patent/YU159291A/sh unknown
-
1993
- 1993-03-26 NO NO931151A patent/NO931151D0/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0550635A1 (en) | 1993-07-14 |
| IL99525A0 (en) | 1992-08-18 |
| DE69109125D1 (de) | 1995-05-24 |
| CN1060285A (zh) | 1992-04-15 |
| MX9101274A (es) | 1992-05-04 |
| JPH06501267A (ja) | 1994-02-10 |
| IE66042B1 (en) | 1995-12-13 |
| YU159291A (sh) | 1994-01-20 |
| BR9106905A (pt) | 1993-08-17 |
| JPH0772175B2 (ja) | 1995-08-02 |
| FI931370L (fi) | 1993-03-26 |
| EP0550635B1 (en) | 1995-04-19 |
| HU9300898D0 (en) | 1993-06-28 |
| ZA917744B (en) | 1993-03-29 |
| FI931370A0 (fi) | 1993-03-26 |
| NO931151L (no) | 1993-03-26 |
| PT99064A (pt) | 1992-08-31 |
| CA2089736A1 (en) | 1992-03-29 |
| IE913396A1 (en) | 1992-04-08 |
| NO931151D0 (no) | 1993-03-26 |
| FI931370A7 (fi) | 1993-03-26 |
| DK0550635T3 (da) | 1995-09-04 |
| WO1992006079A1 (en) | 1992-04-16 |
| HUT68667A (en) | 1995-07-28 |
| AU651145B2 (en) | 1994-07-14 |
| DE69109125T2 (de) | 1995-09-28 |
| TW199144B (cg-RX-API-DMAC7.html) | 1993-02-01 |
| CZ387492A3 (en) | 1994-02-16 |
| AU8746391A (en) | 1992-04-28 |
| ATE121389T1 (de) | 1995-05-15 |
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