ES2054614T3 - Biocatalizadores inmovilizados nuevos, su preparacion y aplicacion. - Google Patents

Biocatalizadores inmovilizados nuevos, su preparacion y aplicacion.

Info

Publication number
ES2054614T3
ES2054614T3 ES86202031T ES86202031T ES2054614T3 ES 2054614 T3 ES2054614 T3 ES 2054614T3 ES 86202031 T ES86202031 T ES 86202031T ES 86202031 T ES86202031 T ES 86202031T ES 2054614 T3 ES2054614 T3 ES 2054614T3
Authority
ES
Spain
Prior art keywords
gelling agent
immobilized
living cells
particles
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES86202031T
Other languages
English (en)
Inventor
Abraham Harder
Haan Ben Rudolf De
Der Plaat Johannes Bertus Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gist Brocades NV
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Application granted granted Critical
Publication of ES2054614T3 publication Critical patent/ES2054614T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/18—Multi-enzyme systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/94—Saccharomyces
    • Y10S435/942—Saccharomyces cerevisiae

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Mycology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

BIOCATALIZADORES INMOVILIZADOS INSOLUBLES EN AGUA EN FORMA DE PARTICULAS CONSTITUIDOS POR CELULAS VIVAS, PARTICULARMENTE LEVADURAS, DISPERSADAS EN UN AGENTE GELIFICANTE RETICULADO. UNA ENZIMA, PARTICULARMENTE LA AMILOGLUCOSIDASA, PUEDE ESTAR CO-INMOVLIZADA EN LAS PARTICULAS. ESTAS PARTICULAS SE PRERARAN SUSPENDIENDO LAS CELULAS VIVAS EN UNA DISOLUCION ACUOSA DE UN AGENTE GELIFICANTE, DISPERSANDO ESTA SUSPENSION EN UN LIQUIDO ORGANICO INMISCIBLE EN AGUA PARA FORMAR UNA SUSPENSION EN EL LIQUIDO DE LAS PARTICULAS ACUOSAS CONSTITUIDAS POR LAS CELULAS VIVAS Y EL AGENTE GELIFICANTE, GELIFICANDO EL GEL Y RETICULANDO EL AGENTE GELIFICANTE. SE ENCUENTRA QUE CUANDO CELULAS VIVAS TALES COMO CELULAS MICROBIANAS Y ESPECIALMENTE LEVADURAS SE INMOVILIZAN DE ESTA MANERA, SORPRENDENTEMENTE, NO SOLAMENTE RETIENEN SU VIABILIDAD, SINO QUE LA CAPACIDAD DE LAS CALULAS DE LEVADURA PARA PRODUCIR ETANOL EN CONDICIONES DE FERMENTACION CONTINUA MEJORAN SIGNIFICATIVAMENTE. SE DESCRIBEN CEPAS ESPECIFICAS DE "SACCHAROMYCES CEREVISIAE", ADECUADAS PARA INMOVILIZACION POR ESTE METODO.
ES86202031T 1985-11-15 1986-11-17 Biocatalizadores inmovilizados nuevos, su preparacion y aplicacion. Expired - Lifetime ES2054614T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP85201883 1985-11-15
EP86304578 1986-06-13

Publications (1)

Publication Number Publication Date
ES2054614T3 true ES2054614T3 (es) 1994-08-16

Family

ID=26097976

Family Applications (1)

Application Number Title Priority Date Filing Date
ES86202031T Expired - Lifetime ES2054614T3 (es) 1985-11-15 1986-11-17 Biocatalizadores inmovilizados nuevos, su preparacion y aplicacion.

Country Status (15)

Country Link
US (1) US5137818A (es)
EP (1) EP0222462B1 (es)
JP (1) JP2575678B2 (es)
KR (1) KR950012803B1 (es)
CN (1) CN1029987C (es)
AT (1) ATE86299T1 (es)
CA (1) CA1337282C (es)
DE (1) DE3687882T2 (es)
DK (1) DK366087A (es)
ES (1) ES2054614T3 (es)
FI (1) FI95044C (es)
GR (1) GR3007372T3 (es)
IE (1) IE59798B1 (es)
PT (1) PT83746B (es)
WO (1) WO1987003005A1 (es)

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ATE230436T1 (de) * 1992-04-29 2003-01-15 Genencor Int Enzym, das in einem träger aus aktivkohle und vernetzter gelatine immobilisiert ist
US5436003A (en) * 1994-02-10 1995-07-25 Triarco Industries, Inc. Method of alleviating gastrointestinal distress with a composition containing beta-fructofuransidase, cellulase and hemi-cellulase
US6099844A (en) * 1994-08-22 2000-08-08 Triarco Industries, Inc. Increasing yield of extractable substances from botanicals with an enzyme composition
EP0839192B1 (en) * 1995-07-18 2008-12-10 DSM IP Assets B.V. An improved immobilized penicillin g acylase
US6060268A (en) * 1995-07-18 2000-05-09 Gist-Brocades B.V. Penicillin G acylase immobilized with a crosslinked mixture of gelled gelatin and amino polymer
WO1998002567A2 (en) 1996-07-16 1998-01-22 Gist-Brocades B.V. PROCESS FOR THE PREPARATION OF CEPHALOSPORINS USING $i(ACREMONIUM CHRYSOGENUM)
DE19714219A1 (de) * 1997-04-07 1998-10-08 Cornelius Prof Dr Friedrich Verfahren und Vorrichtung zur Aktivitätsbestimmung immobilisierter Mikroorganismen
EP0912754B1 (en) 1997-04-22 2004-09-29 DSM IP Assets B.V. Process for the fermentative production of deacylated cephalosporins
ES2191313T3 (es) 1997-04-22 2003-09-01 Dsm Nv Procedimiento para la produccion fermentativa de cefalosporinas desaciladas.
KR100219918B1 (ko) * 1997-07-03 1999-09-01 김윤 대장선택적 약물전달용 조성물
AU4144999A (en) 1998-05-19 1999-12-06 Dsm N.V. Improved (in vivo) production of cephalosporins
NL1009814C2 (nl) * 1998-08-06 2000-02-08 Dsm Nv Werkwijze voor de bereiding van een N-geacyleerd aminonitril.
US6899889B1 (en) * 1998-11-06 2005-05-31 Neomend, Inc. Biocompatible material composition adaptable to diverse therapeutic indications
US6830756B2 (en) * 1998-11-06 2004-12-14 Neomend, Inc. Systems, methods, and compositions for achieving closure of vascular puncture sites
US7074603B2 (en) * 1999-03-11 2006-07-11 Zeachem, Inc. Process for producing ethanol from corn dry milling
ES2400285T3 (es) 1999-03-11 2013-04-08 Zeachem, Inc. Proceso para producir etanol
MX306561B (es) * 2004-01-29 2013-01-09 Zeachem Inc Recuperacion de acidos organicos.
JP4603273B2 (ja) * 2004-02-12 2010-12-22 株式会社ヤクルト本社 固定化微生物担体または固定化酵素担体の製造方法
US20060257492A1 (en) * 2005-05-13 2006-11-16 Depuy Products, Inc. Suspension of calcium phosphate particulates for local delivery of therapeutic agents
AU2008212826A1 (en) * 2007-02-09 2008-08-14 Zeachem Inc. Energy efficient methods to produce products
JP2009131168A (ja) * 2007-11-29 2009-06-18 National Institute Of Advanced Industrial & Technology 廃棄玉ネギの処理方法
EP2252697A4 (en) * 2008-02-07 2012-05-30 Zeachem Inc INDIRECT PRODUCTION OF BUTANOL AND HEXANOL
MX302494B (es) * 2008-05-07 2012-08-17 Zeachem Inc Recuperacion de acidos organicos.
SI2367940T1 (en) 2008-12-23 2018-04-30 Dsm Sinochem Pharmaceuticals Netherlands B.V. Mutated penicillin G acylase
CN102656274B (zh) 2009-12-14 2014-10-15 中化帝斯曼制药有限公司荷兰公司 生产头孢拉定的方法
WO2011113486A1 (en) 2010-03-17 2011-09-22 Deretil, S.A. Process for the synthesis of hydroxyphenylglycine esters
CN103108879B (zh) 2010-09-07 2016-08-17 中化帝斯曼制药有限公司荷兰公司 用于生产头孢菌素类的方法
EP2637711B1 (en) * 2010-11-10 2024-03-27 ProKidney Injectable formulations for organ augmentation
CN102199502B (zh) * 2011-04-25 2012-10-17 吴新芳 一种显著增加白藜芦醇含量的干红葡萄酒的制备方法
EP2723881A2 (en) 2011-06-23 2014-04-30 DSM Sinochem Pharmaceuticals Netherlands B.V. Novel crystalline cefoperazone intermediate
ES2729707T3 (es) 2011-06-23 2019-11-05 Centrient Pharmaceuticals Netherlands B V Proceso de preparación de cefalosporinas 3'-tiosustituidas empleando una penicilina G acilasa
WO2013057197A1 (en) 2011-10-20 2013-04-25 Dsm Sinochem Pharmaceuticals Netherlands B.V. Process for the formylation of cefamandole
WO2013057196A1 (en) 2011-10-20 2013-04-25 Dsm Sinochem Pharmaceuticals Netherlands B.V. Process for the preparation of cefamandole nafate
NZ703529A (en) 2012-06-15 2017-10-27 Microvi Biotech Inc Novel biocatalyst compositions and processes for use
US9752164B2 (en) 2012-06-15 2017-09-05 Microvi Biotech, Inc. Enhanced efficiency ethanol and sugar conversion processes
US9334507B2 (en) 2012-06-15 2016-05-10 Microvi Biotech, Inc. Bioprocesses for making butanol
US9255281B2 (en) 2012-06-15 2016-02-09 Microvi Biotech Inc. Bioconversion processes using water-insoluble liquids
BR102016014767B1 (pt) * 2016-06-14 2021-11-23 Fundação Universidade Federal Do Tocantins Processo para produção de monossacarídeos fermentescíveis a partir de quitina e/ou quitosana
CN109943559B (zh) * 2019-02-25 2021-04-27 车团结 一种固定化发酵剂体系及其制备和应用
GR20200100194A (el) * 2020-04-15 2021-11-11 Πανεπιστημιο Πατρων, Παραγωγη κυτταρικου εργοστασιου sacchaomyces cerevisiae χωρις γενετικη τροποποιηση για ζυμωση κελλοβιοζης και κυτταρινης σε μια παρτιδα
CN113773977B (zh) * 2021-10-16 2023-09-15 贵州医科大学 一种低产乙醇高产香的酵母菌株及其应用

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Also Published As

Publication number Publication date
KR880700854A (ko) 1988-04-12
EP0222462B1 (en) 1993-03-03
EP0222462A1 (en) 1987-05-20
FI873084A (fi) 1987-07-13
GR3007372T3 (es) 1993-07-30
PT83746A (en) 1986-12-01
FI95044B (fi) 1995-08-31
IE863027L (en) 1987-05-15
DK366087D0 (da) 1987-07-14
PT83746B (pt) 1988-08-17
FI95044C (fi) 1995-12-11
JPS63501334A (ja) 1988-05-26
CA1337282C (en) 1995-10-10
CN1029987C (zh) 1995-10-11
DK366087A (da) 1987-07-14
CN86108306A (zh) 1987-10-28
FI873084A0 (fi) 1987-07-13
WO1987003005A1 (en) 1987-05-21
IE59798B1 (en) 1994-04-06
JP2575678B2 (ja) 1997-01-29
DE3687882D1 (de) 1993-04-08
US5137818A (en) 1992-08-11
ATE86299T1 (de) 1993-03-15
KR950012803B1 (ko) 1995-10-21
DE3687882T2 (de) 1993-06-17

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