ES2010439A6 - Procedimiento para la preparacion de nuevas sales antivirales y estimuladoras del sistema inmunologico. - Google Patents
Procedimiento para la preparacion de nuevas sales antivirales y estimuladoras del sistema inmunologico.Info
- Publication number
- ES2010439A6 ES2010439A6 ES8900861A ES8900861A ES2010439A6 ES 2010439 A6 ES2010439 A6 ES 2010439A6 ES 8900861 A ES8900861 A ES 8900861A ES 8900861 A ES8900861 A ES 8900861A ES 2010439 A6 ES2010439 A6 ES 2010439A6
- Authority
- ES
- Spain
- Prior art keywords
- carboxylic acids
- unsaturated carboxylic
- long chain
- chain unsaturated
- salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/24—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/03—Monocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE NUEVAS SALES ANTIVIRALES Y ESTIMULADORAS DEL SISTEMA INMUNOLOGICO. NUEVAS SALES ANTIVIRALES E INMUNOESTIMULADORAS DE LA FORMULA GENERAL (I) R-COO-AH+, EN LA QUE R ES UN GRUPO ALQUILO C18-24 QUE CONTIENE POR LO MENOS DOS ENLACES DOBLES; Y <A> REPRESENTA UN AMINOACIDO QUE SE ENCUENTRA EN LOS ORGANISMOS VIVOS Y/O UN DERIVADO DEL MISMO QUE CONTIENE UN GRUPO CARBOXILO SUSTITUIDO POR UN GRUPO ALQUILO C1-4, POR UN GRUPO AMINO O POR UN CATION DE METAL ALCALINO; QUE CONSISTE EN HACER REACCIONAR UN AMINOACIDO <A> CON UN ACIDO DE LA FORMULA GENERAL (II) R-COOH EN UN DISOLVENTE POLAR. APLICACION EN COMPOSICIONES FARMACEUTICAS DE ACTIVIDAD ANTIVIRAL E INMUNOESTIMULADORA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU881131A HU199775B (en) | 1988-03-09 | 1988-03-09 | Process for production of formed by fatty acids salts of amin acids and medical compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2010439A6 true ES2010439A6 (es) | 1989-11-01 |
Family
ID=10952971
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8900861A Expired ES2010439A6 (es) | 1988-03-09 | 1989-03-09 | Procedimiento para la preparacion de nuevas sales antivirales y estimuladoras del sistema inmunologico. |
Country Status (16)
Country | Link |
---|---|
JP (1) | JP2751068B2 (es) |
KR (1) | KR0140993B1 (es) |
AT (1) | AT398073B (es) |
BE (1) | BE1003663A3 (es) |
CA (1) | CA1339147C (es) |
CH (1) | CH678851A5 (es) |
DE (1) | DE3907688C2 (es) |
ES (1) | ES2010439A6 (es) |
FI (1) | FI93949C (es) |
FR (1) | FR2628419B1 (es) |
GB (1) | GB2216522B (es) |
HU (1) | HU199775B (es) |
IT (1) | IT1229563B (es) |
LU (1) | LU87470A1 (es) |
NL (1) | NL8900573A (es) |
SE (1) | SE508603C2 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04279523A (ja) * | 1991-01-11 | 1992-10-05 | Nisshin Flour Milling Co Ltd | 免疫賦活油脂加工品 |
WO1993000084A1 (en) * | 1991-06-24 | 1993-01-07 | Adelaide Children's Hospital | Methods and compositions for treating malaria and other diseases |
US5767156A (en) * | 1993-10-06 | 1998-06-16 | Peptide Technology Limited | Polyunsaturated fatty acids and uses thereof |
NL9401743A (nl) * | 1994-10-20 | 1996-06-03 | Prospa Bv | Zouten van aminoalcoholen en farmaceutische formuleringen die deze bevatten. |
AUPM906594A0 (en) * | 1994-10-26 | 1994-11-17 | Peptide Technology Limited | Synthetic polyunsaturated fatty acid analogues |
US5639858A (en) * | 1995-03-22 | 1997-06-17 | Tularik, Inc. | Human signal transducer and binding assays |
HU227588B1 (hu) | 2004-12-03 | 2011-09-28 | Sinnex Mueszaki Fejlesztoe Es Tanacsado Kft | Többszörösen telítetlen zsírsavak észtereit tartalmazó vírusellenes és immunstimuláns gyógyászati készítmény |
CN101431989B (zh) | 2005-12-30 | 2011-11-23 | 雷文斯治疗公司 | 局部给药的精氨酸杂聚体 |
HUE048494T2 (hu) * | 2014-12-23 | 2020-07-28 | Evonik Operations Gmbh | Eljárás többszörösen telítetlen omega-3 zsírsavakat tartalmazó készítmény stabilitásának növelésére |
EP3248467A1 (de) | 2016-05-25 | 2017-11-29 | Evonik Technochemie GmbH | Verfahren zur herstellung einer zusammensetzung enthaltend omega-3-fettsäure-l-lysin-salze |
US11622952B2 (en) | 2017-08-15 | 2023-04-11 | Evonik Operations Gmbh | Tablets with high active ingredient content of omega-3 fatty acid amino acid salts |
EP4097202A4 (en) * | 2020-01-30 | 2024-01-03 | Silicycle Inc | METHOD FOR PRODUCING SOLID NEUTRAL AMINO ACID SALTS OF POLYUNSATURATED FATTY ACIDS |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2305553A1 (de) * | 1972-02-04 | 1973-08-09 | Univ Minnesota | Arzneimittel zur behandlung von virusinfektionen |
US4513008A (en) * | 1982-07-30 | 1985-04-23 | The Vinoxen Company, Inc. | Virucidal compositions and therapy |
GB8327911D0 (en) * | 1983-10-19 | 1983-11-23 | Ciba Geigy Ag | Salts as corrosion inhibitors |
US4537772A (en) * | 1984-05-02 | 1985-08-27 | Merck & Co., Inc. | Enhancing absorption of drugs from gastrointestinal tract using acylcarnitines |
FR2587900B1 (fr) * | 1985-10-01 | 1988-10-07 | Morelle Jean | Associations acides gras-acides amines basiques, douees de proprietes emollientes, emulsifiantes et antioxydantes, destinees a la cosmetique, la dermatologie et l'alimentation |
JPS63230632A (ja) * | 1987-03-20 | 1988-09-27 | Nippon Oil & Fats Co Ltd | リポキシゲナ−ゼ代謝刺激剤 |
DE3726299A1 (de) * | 1987-06-26 | 1989-02-23 | Dietl Hans | Fettemulsion zur intravenoesen anwendung |
-
1988
- 1988-03-09 HU HU881131A patent/HU199775B/hu not_active IP Right Cessation
-
1989
- 1989-03-06 CH CH820/89A patent/CH678851A5/de not_active IP Right Cessation
- 1989-03-07 AT AT0050989A patent/AT398073B/de not_active IP Right Cessation
- 1989-03-09 DE DE3907688A patent/DE3907688C2/de not_active Expired - Fee Related
- 1989-03-09 SE SE8900827A patent/SE508603C2/sv not_active IP Right Cessation
- 1989-03-09 JP JP1055241A patent/JP2751068B2/ja not_active Expired - Lifetime
- 1989-03-09 GB GB8905384A patent/GB2216522B/en not_active Expired - Fee Related
- 1989-03-09 KR KR1019890002919A patent/KR0140993B1/ko not_active IP Right Cessation
- 1989-03-09 CA CA000593269A patent/CA1339147C/en not_active Expired - Fee Related
- 1989-03-09 LU LU87470A patent/LU87470A1/fr unknown
- 1989-03-09 BE BE8900253A patent/BE1003663A3/fr not_active IP Right Cessation
- 1989-03-09 IT IT8919705A patent/IT1229563B/it active
- 1989-03-09 ES ES8900861A patent/ES2010439A6/es not_active Expired
- 1989-03-09 NL NL8900573A patent/NL8900573A/nl not_active Application Discontinuation
- 1989-03-09 FI FI891144A patent/FI93949C/fi not_active IP Right Cessation
- 1989-03-09 FR FR898903084A patent/FR2628419B1/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE3907688A1 (de) | 1989-09-21 |
FI93949B (fi) | 1995-03-15 |
KR890014451A (ko) | 1989-10-23 |
BE1003663A3 (fr) | 1992-05-19 |
DE3907688C2 (de) | 1996-09-05 |
FI891144A (fi) | 1989-09-10 |
FR2628419A1 (fr) | 1989-09-15 |
SE8900827L (sv) | 1989-09-10 |
KR0140993B1 (ko) | 1998-07-01 |
FR2628419B1 (fr) | 1992-02-14 |
FI891144A0 (fi) | 1989-03-09 |
HU199775B (en) | 1990-03-28 |
SE508603C2 (sv) | 1998-10-19 |
IT1229563B (it) | 1991-09-04 |
GB2216522B (en) | 1992-01-02 |
GB8905384D0 (en) | 1989-04-19 |
CH678851A5 (es) | 1991-11-15 |
ATA50989A (de) | 1994-01-15 |
GB2216522A (en) | 1989-10-11 |
LU87470A1 (fr) | 1990-10-02 |
IT8919705A0 (it) | 1989-03-09 |
CA1339147C (en) | 1997-07-29 |
NL8900573A (nl) | 1989-10-02 |
FI93949C (fi) | 1995-06-26 |
AT398073B (de) | 1994-09-26 |
HUT49564A (en) | 1989-10-30 |
JP2751068B2 (ja) | 1998-05-18 |
JPH024746A (ja) | 1990-01-09 |
SE8900827D0 (sv) | 1989-03-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20020506 |