ES2099022A1 - Composiciones farmaceuticas que contienen las sales de acido s(+)-2-(4-isobutilfenil) propionico con aminoacidos basicos. - Google Patents
Composiciones farmaceuticas que contienen las sales de acido s(+)-2-(4-isobutilfenil) propionico con aminoacidos basicos.Info
- Publication number
- ES2099022A1 ES2099022A1 ES09401336A ES9401336A ES2099022A1 ES 2099022 A1 ES2099022 A1 ES 2099022A1 ES 09401336 A ES09401336 A ES 09401336A ES 9401336 A ES9401336 A ES 9401336A ES 2099022 A1 ES2099022 A1 ES 2099022A1
- Authority
- ES
- Spain
- Prior art keywords
- isobutylphenyl
- propionic acid
- salts
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
COMPOSICIONES FARMACEUTICAS QUE CONTIENEN SALES DE ACIDO S(+)-2-(4-ISOBUTILFENIL) PROPIONICO CON AMINOACIDOS BASICOS. LAS COMPOSICIONES FARMACEUTICAS CONTIENEN UNA SAL DE S(+)-IBUPROFEN CON UN AMINOACIDO ELEGIDO ENTRE L-ARGININA Y L-LISINA, EN UNA CANTIDAD, EXPRESADA COMO S(+)-IBUPROFEN, SUPERIOR A 200 MG. ESTAS COMPOSICIONES FARMACEUTICAS SE USAN PARA TRATAMIENTO DE PATOLOGIAS QUE COMBINAN DOLOR MODERADO O SEVERO CON CONDICIONES INFLAMATORIAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT93MI001324A IT1264855B1 (it) | 1993-06-21 | 1993-06-21 | Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2099022A1 true ES2099022A1 (es) | 1997-05-01 |
ES2099022B1 ES2099022B1 (es) | 1998-01-16 |
Family
ID=11366435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES09401336A Expired - Fee Related ES2099022B1 (es) | 1993-06-21 | 1994-06-20 | Composiciones farmaceuticas que contienen las sales de acido s(+)-2-(4-isobutilfenil) propionico con aminoacidos basicos. |
Country Status (12)
Country | Link |
---|---|
US (1) | US5510385A (es) |
JP (1) | JPH0710749A (es) |
BE (1) | BE1007193A5 (es) |
CA (1) | CA2125644C (es) |
CH (1) | CH686866A5 (es) |
DE (1) | DE4420858A1 (es) |
ES (1) | ES2099022B1 (es) |
FR (1) | FR2706891B1 (es) |
GB (1) | GB2279251A (es) |
IT (1) | IT1264855B1 (es) |
NL (1) | NL9401006A (es) |
SE (1) | SE9402156L (es) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1146149A (zh) * | 1994-02-24 | 1997-03-26 | 株式会社大塚制药工场 | 增强止痛效果的制剂 |
NZ333474A (en) * | 1998-01-02 | 1999-06-29 | Mcneil Ppc Inc | A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat |
IT1301966B1 (it) | 1998-07-30 | 2000-07-20 | Zambon Spa | Composizioni farmaceutiche ad attivita' analgesica |
US6251426B1 (en) | 1999-09-02 | 2001-06-26 | Banner Pharmacaps, Inc. | Ibuprofen-containing softgels |
US6342530B1 (en) | 2000-11-14 | 2002-01-29 | Farmacon-Il, Llc | Composition and method for parenteral administration of ibuprofen d,l- or l-lysine salt |
US6344479B1 (en) | 2001-03-20 | 2002-02-05 | Farmacon-Il, Llc | Method of preventing retinopathy of prematurity in a neonate |
US7122143B2 (en) | 2001-09-28 | 2006-10-17 | Mcneil-Ppc, Inc. | Methods for manufacturing dosage forms |
BR0212951A (pt) * | 2001-09-28 | 2004-10-26 | Mcneil Ppc Inc | Formas de dosagens compósitas |
US20040253312A1 (en) * | 2001-09-28 | 2004-12-16 | Sowden Harry S. | Immediate release dosage form comprising shell having openings therein |
US7838026B2 (en) | 2001-09-28 | 2010-11-23 | Mcneil-Ppc, Inc. | Burst-release polymer composition and dosage forms comprising the same |
US6727286B2 (en) | 2001-11-02 | 2004-04-27 | Cumberland Pharmaceuticals Inc. | Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid |
CA2519772C (en) | 2003-03-21 | 2016-05-31 | Mcneil-Ppc, Inc. | Use of acetaminophen for providing a sustained therapeutic effect |
US20040186180A1 (en) * | 2003-03-21 | 2004-09-23 | Gelotte Cathy K. | Non-steroidal anti-inflammatory drug dosing regimen |
US20050095300A1 (en) * | 2003-10-30 | 2005-05-05 | Wynn David W. | Controlled release analgesic suspensions |
US20050095299A1 (en) * | 2003-10-30 | 2005-05-05 | Wynn David W. | Controlled release analgesic suspensions |
US8067029B2 (en) | 2004-01-13 | 2011-11-29 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
US7879354B2 (en) | 2004-01-13 | 2011-02-01 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
GB2429916A (en) * | 2004-06-07 | 2007-03-14 | Strides Arcolab Ltd | Pharmaceutical composition containing a stable and clear solution of anti-inflammatory drug in soft gelatin capsule and process for producing the same |
US20050281876A1 (en) | 2004-06-18 | 2005-12-22 | Shun-Por Li | Solid dosage form for acid-labile active ingredient |
US8673352B2 (en) * | 2005-04-15 | 2014-03-18 | Mcneil-Ppc, Inc. | Modified release dosage form |
CA2656540A1 (en) * | 2006-06-30 | 2008-01-10 | Mcneil-Ppc, Inc. | Ibuprofen-containing liquid filled hard capsules |
CN101534795B (zh) | 2006-11-21 | 2013-04-03 | 麦克内尔-Ppc股份有限公司 | 改进释放的镇痛悬浮液 |
US9833510B2 (en) * | 2007-06-12 | 2017-12-05 | Johnson & Johnson Consumer Inc. | Modified release solid or semi-solid dosage forms |
KR101458774B1 (ko) | 2007-08-15 | 2014-11-07 | 맥네일-피피씨, 인코포레이티드 | 즉시 방출 및 지속 방출 이부프로펜 투약 계획 |
US8143314B1 (en) * | 2007-09-13 | 2012-03-27 | Robert Carl Stover | Methods and formulations for treating ineffective or decreased esophageal motility |
CN101390844B (zh) * | 2007-09-23 | 2011-11-09 | 天津医科大学 | 精氨酸布洛芬片剂及其制备方法 |
CN101265178A (zh) * | 2008-04-25 | 2008-09-17 | 北京阜康仁生物制药科技有限公司 | 一种右旋布洛芬的氨基酸盐及其药用组合物 |
BRPI0922263B1 (pt) * | 2008-12-04 | 2021-08-31 | Chongxi Yu | Composição de alta penetração de um fármaco principal, e seus usos |
TW201038296A (en) * | 2009-04-27 | 2010-11-01 | Aplicaciones Farmacodinamicas S A Lab De | Ibuprofen lysinate oral suspension |
CN101978955A (zh) * | 2010-11-05 | 2011-02-23 | 航天中心医院 | 右旋布洛芬氨基酸盐片剂及其制备方法 |
ES2519592T3 (es) * | 2011-11-17 | 2014-11-07 | Zambon S.P.A. | Composiciones sólidas farmacéuticas que contienen sales de ibuprofeno |
WO2013119466A1 (en) | 2012-02-07 | 2013-08-15 | Mcneil-Ppc, Inc. | Rapidly disintegrating coated tablets |
RU2015114433A (ru) | 2012-09-18 | 2016-11-10 | МакНЕЙЛ-ППС, ИНК. | Пероральные дозированные формы с замедленным высвобождением, содержащие частицы легкоплавкого производного пропионовой кислоты |
CN104640537A (zh) | 2012-09-18 | 2015-05-20 | 麦克内尔-Ppc股份有限公司 | 用于口服剂型的低熔点丙酸衍生物粒子 |
CA3242369A1 (en) | 2016-07-19 | 2018-01-25 | Johnson & Johnson Consumer Inc. (A Delaware Corporation) | Tablets having discontinuous coated regions |
US10583089B2 (en) | 2016-07-19 | 2020-03-10 | Johnson & Johnson Consumer Inc. | Tablets having discontinuous coated regions |
CN109937034B (zh) | 2016-11-21 | 2022-09-16 | 济世-伊沃泰克生物制品有限公司 | 阿柏西普制剂及其用途 |
CN111356471A (zh) | 2017-11-20 | 2020-06-30 | 济世发展生物药业有限公司 | 包含赖氨酸盐作为张力调节剂的阿柏西普制剂及其用途 |
EP3743042A1 (en) | 2018-01-22 | 2020-12-02 | Johnson & Johnson Consumer Inc. | Perforated capsules |
US20210378968A1 (en) | 2020-05-28 | 2021-12-09 | Johnson & Johnson Consumer Inc. | Multi-cavity customizable dosage forms |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4994604A (en) * | 1990-01-10 | 1991-02-19 | Merck & Co., Inc. | Formation and resolution of ibuprofen lysinate |
EP0424028A2 (en) * | 1989-10-17 | 1991-04-24 | Merck & Co. Inc. | S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset hastened enhanced analgesics |
EP0505180A1 (en) * | 1991-03-22 | 1992-09-23 | Merck & Co. Inc. | High-content ibuprofen lysinate pharmaceutical formulation |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1209667B (it) * | 1985-11-12 | 1989-08-30 | Zambon Spa | Composizione effeverscente adattivita' analgesica. |
IT1197038B (it) * | 1986-08-01 | 1988-11-25 | Zambon Spa | Composizione farmaceutica ad attivita' analgesica |
US5200558A (en) * | 1989-10-17 | 1993-04-06 | Merck & Co., Inc. | S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset-hastened enhanced analgesics |
US5009895A (en) * | 1990-02-02 | 1991-04-23 | Merck & Co., Inc. | Sustained release with high and low viscosity HPMC |
HUT59656A (en) * | 1990-11-15 | 1992-06-29 | Puetter Medice Chem Pharm | Process for producing s/+/-phenyl-alkanoic acids and alpha-amino-acids containing complexes and pharmaceutical compositions containing them as active components |
US5260337A (en) * | 1992-07-29 | 1993-11-09 | Merck & Co., Inc. | Ibuprofen-muscle relaxant combinations |
-
1993
- 1993-06-21 IT IT93MI001324A patent/IT1264855B1/it active IP Right Grant
-
1994
- 1994-05-20 BE BE9400519A patent/BE1007193A5/fr not_active IP Right Cessation
- 1994-05-30 CH CH01672/94A patent/CH686866A5/it not_active IP Right Cessation
- 1994-05-31 GB GB9410987A patent/GB2279251A/en not_active Withdrawn
- 1994-06-03 FR FR9406817A patent/FR2706891B1/fr not_active Expired - Lifetime
- 1994-06-07 US US08/255,945 patent/US5510385A/en not_active Expired - Lifetime
- 1994-06-10 CA CA002125644A patent/CA2125644C/en not_active Expired - Lifetime
- 1994-06-15 DE DE4420858A patent/DE4420858A1/de not_active Ceased
- 1994-06-20 ES ES09401336A patent/ES2099022B1/es not_active Expired - Fee Related
- 1994-06-20 NL NL9401006A patent/NL9401006A/nl active Search and Examination
- 1994-06-20 SE SE9402156A patent/SE9402156L/xx unknown
- 1994-06-20 JP JP6136833A patent/JPH0710749A/ja active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0424028A2 (en) * | 1989-10-17 | 1991-04-24 | Merck & Co. Inc. | S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset hastened enhanced analgesics |
US4994604A (en) * | 1990-01-10 | 1991-02-19 | Merck & Co., Inc. | Formation and resolution of ibuprofen lysinate |
EP0505180A1 (en) * | 1991-03-22 | 1992-09-23 | Merck & Co. Inc. | High-content ibuprofen lysinate pharmaceutical formulation |
Also Published As
Publication number | Publication date |
---|---|
FR2706891A1 (es) | 1994-12-30 |
ITMI931324A1 (it) | 1994-12-21 |
GB9410987D0 (en) | 1994-07-20 |
CH686866A5 (it) | 1996-07-31 |
ES2099022B1 (es) | 1998-01-16 |
SE9402156D0 (sv) | 1994-06-20 |
ITMI931324A0 (it) | 1993-06-18 |
SE9402156L (sv) | 1994-12-22 |
IT1264855B1 (it) | 1996-10-17 |
FR2706891B1 (es) | 1995-10-20 |
JPH0710749A (ja) | 1995-01-13 |
GB2279251A (en) | 1995-01-04 |
US5510385A (en) | 1996-04-23 |
CA2125644C (en) | 2007-06-05 |
NL9401006A (nl) | 1995-01-16 |
BE1007193A5 (fr) | 1995-04-18 |
DE4420858A1 (de) | 1994-12-22 |
CA2125644A1 (en) | 1994-12-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 19970501 Kind code of ref document: A1 Effective date: 19970501 |
|
FD2A | Announcement of lapse in spain |
Effective date: 20141120 |