ES2099022A1 - Composiciones farmaceuticas que contienen las sales de acido s(+)-2-(4-isobutilfenil) propionico con aminoacidos basicos. - Google Patents

Composiciones farmaceuticas que contienen las sales de acido s(+)-2-(4-isobutilfenil) propionico con aminoacidos basicos.

Info

Publication number
ES2099022A1
ES2099022A1 ES09401336A ES9401336A ES2099022A1 ES 2099022 A1 ES2099022 A1 ES 2099022A1 ES 09401336 A ES09401336 A ES 09401336A ES 9401336 A ES9401336 A ES 9401336A ES 2099022 A1 ES2099022 A1 ES 2099022A1
Authority
ES
Spain
Prior art keywords
isobutylphenyl
propionic acid
salts
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09401336A
Other languages
English (en)
Other versions
ES2099022B1 (es
Inventor
Federico Stroppolo
Daniele Bonadeo
Gian Franco Fornasini
Annibale Gazzaniga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon Group SpA
Zambon SpA
Original Assignee
Zambon Group SpA
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group SpA, Zambon SpA filed Critical Zambon Group SpA
Publication of ES2099022A1 publication Critical patent/ES2099022A1/es
Application granted granted Critical
Publication of ES2099022B1 publication Critical patent/ES2099022B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

COMPOSICIONES FARMACEUTICAS QUE CONTIENEN SALES DE ACIDO S(+)-2-(4-ISOBUTILFENIL) PROPIONICO CON AMINOACIDOS BASICOS. LAS COMPOSICIONES FARMACEUTICAS CONTIENEN UNA SAL DE S(+)-IBUPROFEN CON UN AMINOACIDO ELEGIDO ENTRE L-ARGININA Y L-LISINA, EN UNA CANTIDAD, EXPRESADA COMO S(+)-IBUPROFEN, SUPERIOR A 200 MG. ESTAS COMPOSICIONES FARMACEUTICAS SE USAN PARA TRATAMIENTO DE PATOLOGIAS QUE COMBINAN DOLOR MODERADO O SEVERO CON CONDICIONES INFLAMATORIAS.
ES09401336A 1993-06-21 1994-06-20 Composiciones farmaceuticas que contienen las sales de acido s(+)-2-(4-isobutilfenil) propionico con aminoacidos basicos. Expired - Fee Related ES2099022B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001324A IT1264855B1 (it) 1993-06-21 1993-06-21 Composizioni farmaceutiche contenenti sali dell'acido s(+)-2-(4-isobutilfenil) propionico con amminoacidi basici

Publications (2)

Publication Number Publication Date
ES2099022A1 true ES2099022A1 (es) 1997-05-01
ES2099022B1 ES2099022B1 (es) 1998-01-16

Family

ID=11366435

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09401336A Expired - Fee Related ES2099022B1 (es) 1993-06-21 1994-06-20 Composiciones farmaceuticas que contienen las sales de acido s(+)-2-(4-isobutilfenil) propionico con aminoacidos basicos.

Country Status (12)

Country Link
US (1) US5510385A (es)
JP (1) JPH0710749A (es)
BE (1) BE1007193A5 (es)
CA (1) CA2125644C (es)
CH (1) CH686866A5 (es)
DE (1) DE4420858A1 (es)
ES (1) ES2099022B1 (es)
FR (1) FR2706891B1 (es)
GB (1) GB2279251A (es)
IT (1) IT1264855B1 (es)
NL (1) NL9401006A (es)
SE (1) SE9402156L (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1146149A (zh) * 1994-02-24 1997-03-26 株式会社大塚制药工场 增强止痛效果的制剂
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
US6251426B1 (en) 1999-09-02 2001-06-26 Banner Pharmacaps, Inc. Ibuprofen-containing softgels
US6342530B1 (en) 2000-11-14 2002-01-29 Farmacon-Il, Llc Composition and method for parenteral administration of ibuprofen d,l- or l-lysine salt
US6344479B1 (en) 2001-03-20 2002-02-05 Farmacon-Il, Llc Method of preventing retinopathy of prematurity in a neonate
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
BR0212951A (pt) * 2001-09-28 2004-10-26 Mcneil Ppc Inc Formas de dosagens compósitas
US20040253312A1 (en) * 2001-09-28 2004-12-16 Sowden Harry S. Immediate release dosage form comprising shell having openings therein
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US6727286B2 (en) 2001-11-02 2004-04-27 Cumberland Pharmaceuticals Inc. Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
CA2519772C (en) 2003-03-21 2016-05-31 Mcneil-Ppc, Inc. Use of acetaminophen for providing a sustained therapeutic effect
US20040186180A1 (en) * 2003-03-21 2004-09-23 Gelotte Cathy K. Non-steroidal anti-inflammatory drug dosing regimen
US20050095300A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US20050095299A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US8067029B2 (en) 2004-01-13 2011-11-29 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US7879354B2 (en) 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
GB2429916A (en) * 2004-06-07 2007-03-14 Strides Arcolab Ltd Pharmaceutical composition containing a stable and clear solution of anti-inflammatory drug in soft gelatin capsule and process for producing the same
US20050281876A1 (en) 2004-06-18 2005-12-22 Shun-Por Li Solid dosage form for acid-labile active ingredient
US8673352B2 (en) * 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
CA2656540A1 (en) * 2006-06-30 2008-01-10 Mcneil-Ppc, Inc. Ibuprofen-containing liquid filled hard capsules
CN101534795B (zh) 2006-11-21 2013-04-03 麦克内尔-Ppc股份有限公司 改进释放的镇痛悬浮液
US9833510B2 (en) * 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms
KR101458774B1 (ko) 2007-08-15 2014-11-07 맥네일-피피씨, 인코포레이티드 즉시 방출 및 지속 방출 이부프로펜 투약 계획
US8143314B1 (en) * 2007-09-13 2012-03-27 Robert Carl Stover Methods and formulations for treating ineffective or decreased esophageal motility
CN101390844B (zh) * 2007-09-23 2011-11-09 天津医科大学 精氨酸布洛芬片剂及其制备方法
CN101265178A (zh) * 2008-04-25 2008-09-17 北京阜康仁生物制药科技有限公司 一种右旋布洛芬的氨基酸盐及其药用组合物
BRPI0922263B1 (pt) * 2008-12-04 2021-08-31 Chongxi Yu Composição de alta penetração de um fármaco principal, e seus usos
TW201038296A (en) * 2009-04-27 2010-11-01 Aplicaciones Farmacodinamicas S A Lab De Ibuprofen lysinate oral suspension
CN101978955A (zh) * 2010-11-05 2011-02-23 航天中心医院 右旋布洛芬氨基酸盐片剂及其制备方法
ES2519592T3 (es) * 2011-11-17 2014-11-07 Zambon S.P.A. Composiciones sólidas farmacéuticas que contienen sales de ibuprofeno
WO2013119466A1 (en) 2012-02-07 2013-08-15 Mcneil-Ppc, Inc. Rapidly disintegrating coated tablets
RU2015114433A (ru) 2012-09-18 2016-11-10 МакНЕЙЛ-ППС, ИНК. Пероральные дозированные формы с замедленным высвобождением, содержащие частицы легкоплавкого производного пропионовой кислоты
CN104640537A (zh) 2012-09-18 2015-05-20 麦克内尔-Ppc股份有限公司 用于口服剂型的低熔点丙酸衍生物粒子
CA3242369A1 (en) 2016-07-19 2018-01-25 Johnson & Johnson Consumer Inc. (A Delaware Corporation) Tablets having discontinuous coated regions
US10583089B2 (en) 2016-07-19 2020-03-10 Johnson & Johnson Consumer Inc. Tablets having discontinuous coated regions
CN109937034B (zh) 2016-11-21 2022-09-16 济世-伊沃泰克生物制品有限公司 阿柏西普制剂及其用途
CN111356471A (zh) 2017-11-20 2020-06-30 济世发展生物药业有限公司 包含赖氨酸盐作为张力调节剂的阿柏西普制剂及其用途
EP3743042A1 (en) 2018-01-22 2020-12-02 Johnson & Johnson Consumer Inc. Perforated capsules
US20210378968A1 (en) 2020-05-28 2021-12-09 Johnson & Johnson Consumer Inc. Multi-cavity customizable dosage forms

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994604A (en) * 1990-01-10 1991-02-19 Merck & Co., Inc. Formation and resolution of ibuprofen lysinate
EP0424028A2 (en) * 1989-10-17 1991-04-24 Merck & Co. Inc. S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset hastened enhanced analgesics
EP0505180A1 (en) * 1991-03-22 1992-09-23 Merck & Co. Inc. High-content ibuprofen lysinate pharmaceutical formulation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1209667B (it) * 1985-11-12 1989-08-30 Zambon Spa Composizione effeverscente adattivita' analgesica.
IT1197038B (it) * 1986-08-01 1988-11-25 Zambon Spa Composizione farmaceutica ad attivita' analgesica
US5200558A (en) * 1989-10-17 1993-04-06 Merck & Co., Inc. S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset-hastened enhanced analgesics
US5009895A (en) * 1990-02-02 1991-04-23 Merck & Co., Inc. Sustained release with high and low viscosity HPMC
HUT59656A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing s/+/-phenyl-alkanoic acids and alpha-amino-acids containing complexes and pharmaceutical compositions containing them as active components
US5260337A (en) * 1992-07-29 1993-11-09 Merck & Co., Inc. Ibuprofen-muscle relaxant combinations

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0424028A2 (en) * 1989-10-17 1991-04-24 Merck & Co. Inc. S(+)-ibuprofen-L-amino acid and S(+)-ibuprofen-D-amino acid as onset hastened enhanced analgesics
US4994604A (en) * 1990-01-10 1991-02-19 Merck & Co., Inc. Formation and resolution of ibuprofen lysinate
EP0505180A1 (en) * 1991-03-22 1992-09-23 Merck & Co. Inc. High-content ibuprofen lysinate pharmaceutical formulation

Also Published As

Publication number Publication date
FR2706891A1 (es) 1994-12-30
ITMI931324A1 (it) 1994-12-21
GB9410987D0 (en) 1994-07-20
CH686866A5 (it) 1996-07-31
ES2099022B1 (es) 1998-01-16
SE9402156D0 (sv) 1994-06-20
ITMI931324A0 (it) 1993-06-18
SE9402156L (sv) 1994-12-22
IT1264855B1 (it) 1996-10-17
FR2706891B1 (es) 1995-10-20
JPH0710749A (ja) 1995-01-13
GB2279251A (en) 1995-01-04
US5510385A (en) 1996-04-23
CA2125644C (en) 2007-06-05
NL9401006A (nl) 1995-01-16
BE1007193A5 (fr) 1995-04-18
DE4420858A1 (de) 1994-12-22
CA2125644A1 (en) 1994-12-22

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