ES2099021A1 - Composicion farmaceutica que tiene actividad analgesica. - Google Patents

Composicion farmaceutica que tiene actividad analgesica.

Info

Publication number
ES2099021A1
ES2099021A1 ES09401335A ES9401335A ES2099021A1 ES 2099021 A1 ES2099021 A1 ES 2099021A1 ES 09401335 A ES09401335 A ES 09401335A ES 9401335 A ES9401335 A ES 9401335A ES 2099021 A1 ES2099021 A1 ES 2099021A1
Authority
ES
Spain
Prior art keywords
pharmaceutical composition
analgesic activity
ibuprofen
arginine
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09401335A
Other languages
English (en)
Other versions
ES2099021B1 (es
Inventor
Federico Stroppolo
Daniele Bonadeo
Gian Franco Fornasini
Annibale Gazzaniga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon Group SpA
Zambon SpA
Original Assignee
Zambon Group SpA
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group SpA, Zambon SpA filed Critical Zambon Group SpA
Publication of ES2099021A1 publication Critical patent/ES2099021A1/es
Application granted granted Critical
Publication of ES2099021B1 publication Critical patent/ES2099021B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

COMPOSICION FARMACEUTICA QUE TIENE ACTIVIDAD ANALGESICA. ESTA COMPOSICION ESTA CONSTITUIDA ESENCIALMENTE POR UNA MEZCLA DE ARGININA Y (S)-IBUPROFEN, EN UNA RELACION MOLAR ENTRE 1,1 Y 1,9. ESTAS COMPOSICIONES FARMACEUTICAS SE PUEDEN FORMULAR PARA SU DOSIFICACION EN FORMA DE COMPRIMIDOS, GRANULADOS, POLVOS, JARABES O SOLUCIONES, MEZCLANDOLAS CON EXCIPIENTES FARMACEUTICAMENTE ACEPTABLES. ESTAS COMPOSICIONES FARMACEUTICAS SE USAN PARA LA FORMULACION DE PREPARACIONES FARMACEUTICAS QUE TIENEN UNA SIGNIFICATIVA ANTICIPACION DEL EFECTO ANALGESICO.
ES09401335A 1993-06-21 1994-06-20 Composicion farmaceutica que tiene actividad analgesica. Expired - Fee Related ES2099021B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001325A IT1264856B1 (it) 1993-06-21 1993-06-21 Composizione farmaceutica ad attivita' analgesica

Publications (2)

Publication Number Publication Date
ES2099021A1 true ES2099021A1 (es) 1997-05-01
ES2099021B1 ES2099021B1 (es) 1998-01-16

Family

ID=11366436

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09401335A Expired - Fee Related ES2099021B1 (es) 1993-06-21 1994-06-20 Composicion farmaceutica que tiene actividad analgesica.

Country Status (15)

Country Link
US (2) US5500226A (es)
JP (1) JPH07101855A (es)
BE (1) BE1007194A3 (es)
CA (1) CA2125643C (es)
CH (1) CH687850A5 (es)
DE (1) DE4420856A1 (es)
DK (1) DK174687B1 (es)
ES (1) ES2099021B1 (es)
FR (1) FR2706892B1 (es)
GB (1) GB2279250B (es)
HU (1) HU211669A9 (es)
IT (1) IT1264856B1 (es)
NL (1) NL193820C (es)
NO (1) NO310443B1 (es)
SE (1) SE9402157L (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1264856B1 (it) * 1993-06-21 1996-10-17 Zambon Spa Composizione farmaceutica ad attivita' analgesica
US5654334A (en) * 1995-06-23 1997-08-05 Oklahoma Medical Research Foundation Analgesic use of N-L-α-aspartyl-L-phenylalanine 1-methyl ester
US5707967A (en) * 1995-10-27 1998-01-13 Vanmoor; Arthur Pain relief compositions
CA2266098A1 (en) * 1996-09-26 1998-04-02 Oklahoma Medical Research Foundation Use of n-l-alpha-aspartyl-l-phenylalanine 1-methyl ester and its derivatives in disease regression
WO1999051252A1 (en) 1998-04-03 1999-10-14 The Daily Wellness Company Compositions comprising l-arginine, ginseng and gingko biloba for enhancing blood circulation
IT1301966B1 (it) * 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
KR100523242B1 (ko) * 2000-05-18 2005-10-24 한미약품 주식회사 이부프로펜을 함유하는 정제 조성물
WO2002083105A2 (en) * 2001-04-10 2002-10-24 Zagros Pharma Inc. Composition for enhanced absorption of nsaids
US6727286B2 (en) 2001-11-02 2004-04-27 Cumberland Pharmaceuticals Inc. Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
US20050137262A1 (en) * 2003-12-22 2005-06-23 Hu Patrick C. Highly concentrated pourable aqueous solutions of potassium ibuprofen, their preparation and their uses
KR100678837B1 (ko) * 2005-01-03 2007-02-05 한미약품 주식회사 활성 성분으로 덱시부프로펜을 함유하는 시럽제 조성물 및그의 제조 방법
KR100730393B1 (ko) 2005-06-10 2007-06-20 한국콜마 주식회사 이부프로펜 및 아르기닌을 함유하는 약학 조성물의제조방법
ES2303468B1 (es) * 2007-01-22 2009-06-08 Masterfarm, S.L "una composicion farmaceutica pulverulenta que comprende ibuprofeno".
MX2010004974A (es) * 2010-05-04 2011-11-23 Senosiain S A De C V Lab Combinacion de un aine y un aminoacido.
WO2015016256A1 (ja) * 2013-07-30 2015-02-05 ライオン株式会社 錠剤

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2189994A (en) * 1985-11-12 1987-11-11 Zambon Spa Pharmaceutical compositions containing ibuprofen
GB2193093A (en) * 1986-08-01 1988-02-03 Zambon Spa Ibuprofen compositions
EP0267321A1 (de) * 1986-11-14 1988-05-18 MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG Ibuprofen enthaltendes Arzneimittel
WO1989000421A1 (en) * 1987-07-10 1989-01-26 Abraham Sunshine A pharmaceutical composition containing s(+) ibuprofen substantially free of its r(-) antipode

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262179A (en) * 1989-09-13 1993-11-16 Nicholas Kiwi Pty Ltd. Non-effervescent ibuprofen compositions
ATE128452T1 (de) * 1989-10-17 1995-10-15 Merck & Co Inc S(+)-ibuprofen-l-aminosäure und s(+)-ibuprofen-d- aminosäure als analgetika mit grösserem pharmakologischem potential.
IT1264856B1 (it) * 1993-06-21 1996-10-17 Zambon Spa Composizione farmaceutica ad attivita' analgesica

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2189994A (en) * 1985-11-12 1987-11-11 Zambon Spa Pharmaceutical compositions containing ibuprofen
GB2193093A (en) * 1986-08-01 1988-02-03 Zambon Spa Ibuprofen compositions
EP0267321A1 (de) * 1986-11-14 1988-05-18 MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG Ibuprofen enthaltendes Arzneimittel
WO1989000421A1 (en) * 1987-07-10 1989-01-26 Abraham Sunshine A pharmaceutical composition containing s(+) ibuprofen substantially free of its r(-) antipode

Also Published As

Publication number Publication date
DK72594A (da) 1994-12-22
BE1007194A3 (fr) 1995-04-18
IT1264856B1 (it) 1996-10-17
CH687850A5 (it) 1997-03-14
NL193820B (nl) 2000-08-01
US5500226A (en) 1996-03-19
DK174687B1 (da) 2003-09-15
JPH07101855A (ja) 1995-04-18
CA2125643C (en) 2007-09-04
NO942343L (no) 1994-12-22
FR2706892A1 (es) 1994-12-30
CA2125643A1 (en) 1994-12-22
NO310443B1 (no) 2001-07-09
GB9410898D0 (en) 1994-07-20
ITMI931325A1 (it) 1994-12-21
SE9402157D0 (sv) 1994-06-20
HU211669A9 (en) 1995-12-28
NL193820C (nl) 2000-12-04
GB2279250A (en) 1995-01-04
NL9401005A (nl) 1995-01-16
NO942343D0 (es) 1994-06-20
DE4420856A1 (de) 1994-12-22
GB2279250B (en) 1998-02-25
US5645857A (en) 1997-07-08
SE9402157L (sv) 1994-12-22
ITMI931325A0 (it) 1993-06-21
ES2099021B1 (es) 1998-01-16
FR2706892B1 (es) 1995-10-20

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