ES2002543A6 - Procedimiento de preparacion de nuevos derivados tiazol (4,5-c) quinoleinas y de sus sales de adicion acidas - Google Patents

Procedimiento de preparacion de nuevos derivados tiazol (4,5-c) quinoleinas y de sus sales de adicion acidas

Info

Publication number
ES2002543A6
ES2002543A6 ES8603003A ES8603003A ES2002543A6 ES 2002543 A6 ES2002543 A6 ES 2002543A6 ES 8603003 A ES8603003 A ES 8603003A ES 8603003 A ES8603003 A ES 8603003A ES 2002543 A6 ES2002543 A6 ES 2002543A6
Authority
ES
Spain
Prior art keywords
general formula
phenyl
thiazolo
hydrogen
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8603003A
Other languages
English (en)
Inventor
Jozsef Knoll
Edit Berenyi
Katalin Budai
Berta Knoll
Zsusa Furts
Julia Timssr
Gabriella Zsila
Ildiko Niklya
Lujza Petocz
Attila Mandi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ES2002543A6 publication Critical patent/ES2002543A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO DE PREPARACION DE NUEVOS DERIVADOS TIAZOL-4,5-C-QUINOLEINOS Y SUS SALES DE ADICION ACIDAS. LA INVENCION SE RELACIONA CON UN PROCEDIMIENTO DE PREPARACION DE NUEVOS DERIVADOS DE TIAZOL-4,5-C-QUINOLEINAS DE FORMULA GENERAL I, EN LA QUE R REPRESENTA HIDROGENO, ALQUILO INFERIOR LINEAL O RAMIFICADO, OPTATIVAMENTE SUSTITUIDO POR HALOGENO, FENILO O ALQUILFENILO, SUSTITUIDO O NO; R1 Y R2, IDENTICOS O DIFERENTES, REPRESENTAN HIDROGENO, HALOGENO O ALCOXILO INFERIOR; CARACTERIZADO PORQUE SE HACE REACCIONAR UN DERIVADO 3-AMINO-4-MERCAPT-QUINOLEINA CON UN DERIVADO DE ACIDO CARBOXILICO O DE ALDEHILO, SEGUIDO DE LA CICLACION DEL PRODUCTO ASI OBTENIDO. LOS COMPUESTOS ASI OBTENIDOS POSEEN VALIOSAS PROPIEDADES DEPRESORAS DEL SISTEMA NERVIOSO CENTRAL.
ES8603003A 1985-11-12 1986-11-12 Procedimiento de preparacion de nuevos derivados tiazol (4,5-c) quinoleinas y de sus sales de adicion acidas Expired ES2002543A6 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU854304A HU197019B (en) 1985-11-12 1985-11-12 Process for producing thiqzolo (4,5-c) quinoline derivatives and pharmaceuticals comprising same

Publications (1)

Publication Number Publication Date
ES2002543A6 true ES2002543A6 (es) 1988-08-16

Family

ID=10967593

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8603003A Expired ES2002543A6 (es) 1985-11-12 1986-11-12 Procedimiento de preparacion de nuevos derivados tiazol (4,5-c) quinoleinas y de sus sales de adicion acidas

Country Status (24)

Country Link
US (1) US4904669A (es)
JP (1) JPS62161792A (es)
CN (1) CN86107754A (es)
AU (1) AU592384B2 (es)
BE (1) BE905719A (es)
BG (1) BG46156A3 (es)
CH (1) CH670829A5 (es)
DD (1) DD254202A5 (es)
DE (1) DE3638563A1 (es)
DK (1) DK539786A (es)
ES (1) ES2002543A6 (es)
FI (1) FI864611A (es)
FR (1) FR2603588A1 (es)
GB (1) GB2184117B (es)
HU (1) HU197019B (es)
IL (1) IL80611A0 (es)
IT (1) IT1213379B (es)
NL (1) NL8602878A (es)
NO (1) NO864518L (es)
PL (1) PL148186B1 (es)
SE (1) SE8604839L (es)
SU (1) SU1544190A3 (es)
YU (1) YU192186A (es)
ZA (1) ZA868583B (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU199423B (en) * 1987-04-24 1990-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing 3-amino-4-/ethylthio/-quinoline and pharmaceutical compositions comprising such compounds
US6110929A (en) 1998-07-28 2000-08-29 3M Innovative Properties Company Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof
US6677347B2 (en) * 2000-12-08 2004-01-13 3M Innovative Properties Company Sulfonamido ether substituted imidazoquinolines
WO2004096144A2 (en) * 2003-04-28 2004-11-11 3M Innovative Properties Company Compositions and methods for induction of opioid receptors
AU2004266658A1 (en) * 2003-08-12 2005-03-03 3M Innovative Properties Company Hydroxylamine substituted imidazo-containing compounds
KR101106812B1 (ko) * 2003-08-27 2012-01-19 쓰리엠 이노베이티브 프로퍼티즈 컴파니 아릴옥시 및 아릴알킬렌옥시 치환된 이미다조퀴놀린
EP1660026A4 (en) * 2003-09-05 2008-07-16 3M Innovative Properties Co TREATMENT FOR CD5 + B CELL LYMPHOMA
US7544697B2 (en) * 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
JP5043435B2 (ja) * 2003-10-03 2012-10-10 スリーエム イノベイティブ プロパティズ カンパニー アルコキシ置換イミダゾキノリン
US20090075980A1 (en) * 2003-10-03 2009-03-19 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and Analogs Thereof
JP2007511535A (ja) * 2003-11-14 2007-05-10 スリーエム イノベイティブ プロパティズ カンパニー ヒドロキシルアミン置換イミダゾ環化合物
EP1685129A4 (en) 2003-11-14 2008-10-22 3M Innovative Properties Co OXIMSUBSTITUTED IMIDAZORING CONNECTIONS
WO2005051317A2 (en) * 2003-11-25 2005-06-09 3M Innovative Properties Company Substituted imidazo ring systems and methods
US8802853B2 (en) * 2003-12-29 2014-08-12 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
JP2007517044A (ja) * 2003-12-30 2007-06-28 スリーエム イノベイティブ プロパティズ カンパニー イミダゾキノリニル、イミダゾピリジニル、およびイミダゾナフチリジニルスルホンアミド
WO2005094531A2 (en) * 2004-03-24 2005-10-13 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
US8017779B2 (en) * 2004-06-15 2011-09-13 3M Innovative Properties Company Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
US7897609B2 (en) * 2004-06-18 2011-03-01 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
WO2006065280A2 (en) * 2004-06-18 2006-06-22 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
US8026366B2 (en) * 2004-06-18 2011-09-27 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
US20070259881A1 (en) * 2004-06-18 2007-11-08 Dellaria Joseph F Jr Substituted Imidazo Ring Systems and Methods
US20090270443A1 (en) * 2004-09-02 2009-10-29 Doris Stoermer 1-amino imidazo-containing compounds and methods
EP1819364A4 (en) * 2004-12-08 2010-12-29 3M Innovative Properties Co COMPOSITIONS, IMMUNOMODULATORY COMBINATIONS AND ASSOCIATED METHODS
WO2006083440A2 (en) 2004-12-30 2006-08-10 3M Innovative Properties Company Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
US7943609B2 (en) * 2004-12-30 2011-05-17 3M Innovative Proprerties Company Chiral fused [1,2]imidazo[4,5-C] ring compounds
CA2597092A1 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune reponse modifiers
JP2008530252A (ja) * 2005-02-09 2008-08-07 コーリー ファーマシューティカル グループ，インコーポレイテッド オキシムおよびヒドロキシルアミンで置換されたチアゾロ［４，５−ｃ］環化合物ならびに方法
EP1846405A2 (en) 2005-02-11 2007-10-24 3M Innovative Properties Company Oxime and hydroxylamine substituted imidazo 4,5-c ring compounds and methods
JP2008535832A (ja) 2005-04-01 2008-09-04 コーリー ファーマシューティカル グループ，インコーポレイテッド ピラゾロピリジン−１，４−ジアミン、およびそのアナログ
CA2602590A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
US7906506B2 (en) * 2006-07-12 2011-03-15 3M Innovative Properties Company Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
AU2019363569A1 (en) 2018-10-23 2021-04-29 Basf Se Tricyclic pesticidal compounds
CN115427408A (zh) 2020-04-14 2022-12-02 巴斯夫欧洲公司 杀害虫的三环化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2024207A (en) * 1978-05-26 1980-01-09 Lepetit Spa New tricyclic ortho-fused heterocyclic compounds
HU196308B (en) * 1985-11-12 1988-11-28 Egyt Gyogyszervegyeszeti Gyar Process for producing pharmaceutical compositions containing 2-methyl-thiazolo/4,5-c/quinoline as active component

Also Published As

Publication number Publication date
PL262346A1 (en) 1988-03-03
FI864611A0 (fi) 1986-11-12
CH670829A5 (es) 1989-07-14
YU192186A (en) 1988-10-31
SE8604839L (sv) 1987-05-13
IT8622312A0 (it) 1986-11-12
DK539786D0 (da) 1986-11-12
SE8604839D0 (sv) 1986-11-12
NO864518L (no) 1987-05-13
HU197019B (en) 1989-02-28
DD254202A5 (de) 1988-02-17
NL8602878A (nl) 1987-06-01
HUT44260A (en) 1988-02-29
GB8627043D0 (en) 1986-12-10
DE3638563A1 (de) 1987-06-25
DK539786A (da) 1987-05-13
AU6508986A (en) 1987-05-14
JPS62161792A (ja) 1987-07-17
GB2184117B (en) 1989-10-11
CN86107754A (zh) 1987-08-05
IT1213379B (it) 1989-12-20
PL148186B1 (en) 1989-09-30
IL80611A0 (en) 1987-02-27
BG46156A3 (en) 1989-10-16
NO864518D0 (no) 1986-11-12
FR2603588A1 (fr) 1988-03-11
US4904669A (en) 1990-02-27
AU592384B2 (en) 1990-01-11
SU1544190A3 (ru) 1990-02-15
BE905719A (fr) 1987-05-07
ZA868583B (en) 1987-08-26
GB2184117A (en) 1987-06-17
FI864611A (fi) 1987-05-13

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20100623