FR2603588A1 - Thiazolo (4,5-c) quinoleines, procede de preparation et medicaments les contenant - Google Patents

Thiazolo (4,5-c) quinoleines, procede de preparation et medicaments les contenant

Info

Publication number
FR2603588A1
FR2603588A1 FR8615655A FR8615655A FR2603588A1 FR 2603588 A1 FR2603588 A1 FR 2603588A1 FR 8615655 A FR8615655 A FR 8615655A FR 8615655 A FR8615655 A FR 8615655A FR 2603588 A1 FR2603588 A1 FR 2603588A1
Authority
FR
France
Prior art keywords
thiazolo
group
quinoleines
preparation
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR8615655A
Other languages
English (en)
Inventor
Jozsef Knoll
Edit Berenyli
Katalin Budai
Berta Knoll
Zsuzsa Furts
Julia Timar
Gabriella Zsila
Ildiko Niklya
Lujza Petocz
Attila Mandi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of FR2603588A1 publication Critical patent/FR2603588A1/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRESENTE INVENTION EST RELATIVE A DES DERIVES DE THIAZOLO 4,5-C QUINOLEINE DE FORMULE I : (CF DESSIN DANS BOPI) DANS LAQUELLE : R EST UN ATOME D'HYDROGENE; UN GROUPE ALCOYLE A CHAINE LINEAIRE OU RAMIFIEE AYANT 2 A 5 ATOMES DE CARBONE EVENTUELLEMENT SUBSTITUE PAR UN OU PLUSIEURS ATOMES D'HALOGENE; UN GROUPE PHENYLE OU PHENYLALCOYLE INFERIEUR DONT LE CYCLE PHENYLE PORTE EVENTUELLEMENT UN OU PLUSIEURS SUBSTITUANTS; R ET R SONT IDENTIQUES OU DIFFERENTS ET REPRESENTENT UN ATOME D'HYDROGENE, D'HALOGENE OU UN GROUPE ALCOYLE INFERIEUR, ET LEURS SELS D'ADDITION ACIDES. UTILISATION EN TANT QUE MEDICAMENTS AYANT UN EFFET DEPRESSEUR SUR LE SYSTEME NERVEUX CENTRAL.
FR8615655A 1985-11-12 1986-11-12 Thiazolo (4,5-c) quinoleines, procede de preparation et medicaments les contenant Pending FR2603588A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU854304A HU197019B (en) 1985-11-12 1985-11-12 Process for producing thiqzolo (4,5-c) quinoline derivatives and pharmaceuticals comprising same

Publications (1)

Publication Number Publication Date
FR2603588A1 true FR2603588A1 (fr) 1988-03-11

Family

ID=10967593

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8615655A Pending FR2603588A1 (fr) 1985-11-12 1986-11-12 Thiazolo (4,5-c) quinoleines, procede de preparation et medicaments les contenant

Country Status (24)

Country Link
US (1) US4904669A (fr)
JP (1) JPS62161792A (fr)
CN (1) CN86107754A (fr)
AU (1) AU592384B2 (fr)
BE (1) BE905719A (fr)
BG (1) BG46156A3 (fr)
CH (1) CH670829A5 (fr)
DD (1) DD254202A5 (fr)
DE (1) DE3638563A1 (fr)
DK (1) DK539786A (fr)
ES (1) ES2002543A6 (fr)
FI (1) FI864611A (fr)
FR (1) FR2603588A1 (fr)
GB (1) GB2184117B (fr)
HU (1) HU197019B (fr)
IL (1) IL80611A0 (fr)
IT (1) IT1213379B (fr)
NL (1) NL8602878A (fr)
NO (1) NO864518L (fr)
PL (1) PL148186B1 (fr)
SE (1) SE8604839L (fr)
SU (1) SU1544190A3 (fr)
YU (1) YU192186A (fr)
ZA (1) ZA868583B (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU199423B (en) * 1987-04-24 1990-02-28 Egyt Gyogyszervegyeszeti Gyar Process for producing 3-amino-4-/ethylthio/-quinoline and pharmaceutical compositions comprising such compounds
US6110929A (en) 1998-07-28 2000-08-29 3M Innovative Properties Company Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof
US6677347B2 (en) * 2000-12-08 2004-01-13 3M Innovative Properties Company Sulfonamido ether substituted imidazoquinolines
US20040214851A1 (en) * 2003-04-28 2004-10-28 3M Innovative Properties Company Compositions and methods for induction of opioid receptors
US7648997B2 (en) * 2003-08-12 2010-01-19 Coley Pharmaceutical Group, Inc. Hydroxylamine substituted imidazoquinolines
NZ545412A (en) * 2003-08-27 2008-12-24 Coley Pharm Group Inc Aryloxy and arylalkyleneoxy substituted imidazoquinolines
US20050054665A1 (en) * 2003-09-05 2005-03-10 3M Innovative Properties Company Treatment for CD5+ B cell lymphoma
US20090075980A1 (en) * 2003-10-03 2009-03-19 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and Analogs Thereof
BRPI0414856A (pt) * 2003-10-03 2006-11-21 3M Innovative Properties Co imidazoquinolinas alcóxi-substituìdas
US7544697B2 (en) * 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
CN1906192A (zh) * 2003-11-14 2007-01-31 3M创新有限公司 羟胺取代的咪唑环化合物
US7897767B2 (en) 2003-11-14 2011-03-01 3M Innovative Properties Company Oxime substituted imidazoquinolines
KR101130928B1 (ko) * 2003-11-25 2012-04-12 쓰리엠 이노베이티브 프로퍼티즈 컴파니 치환된 이미다조 고리 시스템 및 방법
EP1701955A1 (fr) * 2003-12-29 2006-09-20 3M Innovative Properties Company Imidazoquinolines a substitution arylalcenyle et arylalkynyle
WO2005066169A2 (fr) * 2003-12-30 2005-07-21 3M Innovative Properties Company Sulfonamides d'imidazoquinolinyle, d'imidazopyridinyle et d'imidazonaphtyridinyle
US8697873B2 (en) * 2004-03-24 2014-04-15 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
US8017779B2 (en) * 2004-06-15 2011-09-13 3M Innovative Properties Company Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
WO2006038923A2 (fr) * 2004-06-18 2006-04-13 3M Innovative Properties Company Imidazonaphthyridines substituees par aryle
WO2006065280A2 (fr) * 2004-06-18 2006-06-22 3M Innovative Properties Company Composes a noyau imidazo a substitutif d'isoxazole, de dihydroisoxazole et d'oxadiazole
US8026366B2 (en) * 2004-06-18 2011-09-27 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
WO2006009832A1 (fr) * 2004-06-18 2006-01-26 3M Innovative Properties Company Systemes cycliques imidazo substitues, et procedes correspondants
WO2006026760A2 (fr) * 2004-09-02 2006-03-09 3M Innovative Properties Company Composes renfermant un 1-amino imidazo et procedes
JP2008523076A (ja) * 2004-12-08 2008-07-03 スリーエム イノベイティブ プロパティズ カンパニー 免疫調節性の組成物、合剤、および方法
ES2392648T3 (es) 2004-12-30 2012-12-12 3M Innovative Properties Company Compuestos quirales sustituidos que contienen un núcleo 1,2-imidazo-4,5-c condensado
JP5543068B2 (ja) * 2004-12-30 2014-07-09 スリーエム イノベイティブ プロパティズ カンパニー キラル縮合［１，２］イミダゾ［４，５−ｃ］環状化合物
JP2008530022A (ja) 2005-02-04 2008-08-07 コーリー ファーマシューティカル グループ，インコーポレイテッド 免疫反応調節物質を含む水性ゲル処方物
AU2006338521A1 (en) * 2005-02-09 2007-10-11 Coley Pharmaceutical Group, Inc. Oxime and hydroxylamine substituted thiazolo(4,5-c) ring compounds and methods
WO2006086634A2 (fr) 2005-02-11 2006-08-17 Coley Pharmaceutical Group, Inc. Composes cycliques imidazo[4,5-c] substitues par oxime et hydroxylamine et procedes associes
JP2008538550A (ja) 2005-04-01 2008-10-30 コーリー ファーマシューティカル グループ，インコーポレイテッド ウイルス感染および腫瘍性疾患を処置するためのサイトカイン生合成の調節因子としての１−置換ピラゾロ（３，４−ｃ）環状化合物
EP1869043A2 (fr) 2005-04-01 2007-12-26 Coley Pharmaceutical Group, Inc. Pyrazolopyridine-1,4-diamines et analogues associes
WO2008008432A2 (fr) * 2006-07-12 2008-01-17 Coley Pharmaceutical Group, Inc. Composés à cycle [1,2] imidazo [4,5-c] fusionné chiral substitué et procédés correspondants
US20210347777A1 (en) 2018-10-23 2021-11-11 Basf Se Tricyclic pesticidal compounds
MX2022012852A (es) 2020-04-14 2022-11-07 Basf Se Compuestos plaguicidas triciclicos.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2024207A (en) * 1978-05-26 1980-01-09 Lepetit Spa New tricyclic ortho-fused heterocyclic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196308B (en) * 1985-11-12 1988-11-28 Egyt Gyogyszervegyeszeti Gyar Process for producing pharmaceutical compositions containing 2-methyl-thiazolo/4,5-c/quinoline as active component

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2024207A (en) * 1978-05-26 1980-01-09 Lepetit Spa New tricyclic ortho-fused heterocyclic compounds

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ARZNEIMITTEL-FORSCHUNG (DRUG RESEARCH) *
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY *

Also Published As

Publication number Publication date
FI864611A0 (fi) 1986-11-12
NO864518D0 (no) 1986-11-12
DK539786D0 (da) 1986-11-12
PL262346A1 (en) 1988-03-03
BG46156A3 (en) 1989-10-16
SE8604839L (sv) 1987-05-13
SE8604839D0 (sv) 1986-11-12
HUT44260A (en) 1988-02-29
GB2184117B (en) 1989-10-11
NL8602878A (nl) 1987-06-01
DD254202A5 (de) 1988-02-17
CH670829A5 (fr) 1989-07-14
CN86107754A (zh) 1987-08-05
NO864518L (no) 1987-05-13
ZA868583B (en) 1987-08-26
HU197019B (en) 1989-02-28
IL80611A0 (en) 1987-02-27
IT1213379B (it) 1989-12-20
AU592384B2 (en) 1990-01-11
AU6508986A (en) 1987-05-14
BE905719A (fr) 1987-05-07
ES2002543A6 (es) 1988-08-16
JPS62161792A (ja) 1987-07-17
GB8627043D0 (en) 1986-12-10
PL148186B1 (en) 1989-09-30
DK539786A (da) 1987-05-13
SU1544190A3 (ru) 1990-02-15
US4904669A (en) 1990-02-27
IT8622312A0 (it) 1986-11-12
DE3638563A1 (de) 1987-06-25
FI864611A (fi) 1987-05-13
GB2184117A (en) 1987-06-17
YU192186A (en) 1988-10-31

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