EP3066190A4 - Dispositifs microfluidiques et procédés de fabrication et d'utilisation de ces dispositifs - Google Patents

Dispositifs microfluidiques et procédés de fabrication et d'utilisation de ces dispositifs Download PDF

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Publication number
EP3066190A4
EP3066190A4 EP14859826.1A EP14859826A EP3066190A4 EP 3066190 A4 EP3066190 A4 EP 3066190A4 EP 14859826 A EP14859826 A EP 14859826A EP 3066190 A4 EP3066190 A4 EP 3066190A4
Authority
EP
European Patent Office
Prior art keywords
making
methods
same
microfluidic devices
microfluidic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP14859826.1A
Other languages
German (de)
English (en)
Other versions
EP3066190B1 (fr
EP3066190A1 (fr
Inventor
Scott Joseph Bornheimer
Jeffrey Sugarman
Wei Huang
Edward Michael Goldberg
Ming Tan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of EP3066190A1 publication Critical patent/EP3066190A1/fr
Publication of EP3066190A4 publication Critical patent/EP3066190A4/fr
Application granted granted Critical
Publication of EP3066190B1 publication Critical patent/EP3066190B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/45—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads
    • B01F25/452—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces
    • B01F25/4522—Mixers in which the materials to be mixed are pressed together through orifices or interstitial spaces, e.g. between beads characterised by elements provided with orifices or interstitial spaces the components being pressed through porous bodies, e.g. flat plates, blocks or cylinders, which obstruct the whole diameter of the tube
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2215/00—Auxiliary or complementary information in relation with mixing
    • B01F2215/04—Technical information in relation with mixing
    • B01F2215/0413—Numerical information
    • B01F2215/0418—Geometrical information
    • B01F2215/0431—Numerical size values, e.g. diameter of a hole or conduit, area, volume, length, width, or ratios thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
EP14859826.1A 2013-11-06 2014-11-05 Dispositifs microfluidiques et procédés d'utilisation de ces dispositifs Active EP3066190B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361900590P 2013-11-06 2013-11-06
PCT/US2014/064159 WO2015069789A1 (fr) 2013-11-06 2014-11-05 Dispositifs microfluidiques et procédés de fabrication et d'utilisation de ces dispositifs

Publications (3)

Publication Number Publication Date
EP3066190A1 EP3066190A1 (fr) 2016-09-14
EP3066190A4 true EP3066190A4 (fr) 2017-07-05
EP3066190B1 EP3066190B1 (fr) 2020-12-30

Family

ID=53007309

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14859826.1A Active EP3066190B1 (fr) 2013-11-06 2014-11-05 Dispositifs microfluidiques et procédés d'utilisation de ces dispositifs

Country Status (9)

Country Link
US (2) US9797899B2 (fr)
EP (1) EP3066190B1 (fr)
JP (1) JP6632525B2 (fr)
CN (2) CN113477149B (fr)
AU (1) AU2014346787B2 (fr)
BR (1) BR112016009958B1 (fr)
ES (1) ES2856191T3 (fr)
WO (1) WO2015069789A1 (fr)
ZA (1) ZA201602792B (fr)

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US10018640B2 (en) 2013-11-13 2018-07-10 Becton, Dickinson And Company Optical imaging system and methods for using the same
BR122020024283B1 (pt) 2014-10-14 2023-02-23 Becton, Dickinson And Company Dispositivo de transferência de sangue adaptado para receber uma amostra de sangue
PL3094252T3 (pl) 2014-10-14 2022-02-21 Becton, Dickinson And Company Zarządzanie próbką krwi z zastosowaniem pianki otwartokomórkowej
US10111610B2 (en) 2014-11-04 2018-10-30 Wainamics, Inc. Microscale plasma separator
AU2016229837B2 (en) 2015-03-10 2018-05-24 Becton, Dickinson And Company Biological fluid micro-sample management device
JP2018536142A (ja) 2015-09-01 2018-12-06 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ 試料の相を分離するためのデプスフィルトレーションデバイス
WO2017044887A1 (fr) 2015-09-09 2017-03-16 Drawbridge Health, Inc. Systèmes, procédés et dispositifs pour le prélèvement, la stabilisation et la conservation d'échantillons
FR3041547B1 (fr) * 2015-09-29 2019-09-20 Francois Parmentier Procede de chromatographie sur un garnissage poreux fabrique par etirage
CA3018266A1 (fr) 2016-04-22 2017-10-26 Becton, Dickinson And Company Dispositifs a colorants polymeres multiplex et leurs methodes d'utilisation
JP6635897B2 (ja) * 2016-08-30 2020-01-29 シスメックス株式会社 試料分析用カートリッジ及びその製造方法、並びにその利用
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CN210383905U (zh) 2017-01-10 2020-04-24 集联健康有限公司 一种用于从受试者收集流体样品的装置以及运输套筒
CA3052595A1 (fr) 2017-02-08 2018-08-16 Becton, Dickinson And Company Dispositifs reactifs pour du colorant seche et leurs procedes de fabrication et d'utilisation
US11266988B2 (en) * 2017-03-20 2022-03-08 Wainamics, Inc. Small volume self-metered blood separation device
WO2019157532A1 (fr) * 2018-02-12 2019-08-15 Athelas, Inc. Dispositif d'analyse à chargement capillaire pour échantillons de fluide biologique
US20210039096A1 (en) * 2018-04-06 2021-02-11 Redbud Labs, Inc. Magnetic-based actuation mechanisms for and methods of actuating magnetically responsive microposts in a reaction chamber
CN113196056B (zh) * 2018-09-19 2024-10-29 卢米瑞德思英国有限公司 分析
CN113396006A (zh) 2018-11-13 2021-09-14 贝克顿·迪金森公司 干燥试剂滤网及其制造和使用方法
CN110218776A (zh) * 2019-06-14 2019-09-10 苏州叠代生物科技有限公司 Pcr油相组合物及其制备方法
CN110538680B (zh) * 2019-08-19 2024-08-06 昆山汇先医药技术有限公司 一种微流控样品处理设备
WO2021188435A1 (fr) 2020-03-17 2021-09-23 Becton, Dickinson And Company Amplificateurs adaptés en gain pour détection de lumière
FR3109585A1 (fr) * 2020-04-28 2021-10-29 Withings Plaquette de test et système de test biologique automatisé
CN115917315A (zh) 2020-05-05 2023-04-04 贝克顿·迪金森公司 用于确定流式细胞仪中检测器增益的方法
US11904314B2 (en) 2020-07-30 2024-02-20 Wainamics, Inc. System and self-metering cartridges for point of care bioassays
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JP7567276B2 (ja) 2020-08-20 2024-10-16 大日本印刷株式会社 試薬担持基材、試薬入りマイクロ流路構造体、及び試薬入りマイクロ流路デバイス
CN116057365A (zh) * 2020-09-11 2023-05-02 贝克顿·迪金森公司 用于测试环境样品的装置
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US20180011090A1 (en) 2018-01-11
US9797899B2 (en) 2017-10-24
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