EP1947027B1 - Blisterpackung und Verfahren zur vorübergehenden Lagerung von Produkten - Google Patents

Blisterpackung und Verfahren zur vorübergehenden Lagerung von Produkten Download PDF

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Publication number
EP1947027B1
EP1947027B1 EP07100898A EP07100898A EP1947027B1 EP 1947027 B1 EP1947027 B1 EP 1947027B1 EP 07100898 A EP07100898 A EP 07100898A EP 07100898 A EP07100898 A EP 07100898A EP 1947027 B1 EP1947027 B1 EP 1947027B1
Authority
EP
European Patent Office
Prior art keywords
film
layer
blister packaging
blister
receiving compartments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP07100898A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1947027A1 (de
Inventor
Edwin Kohl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AT07100898T priority Critical patent/ATE461876T1/de
Application filed by Individual filed Critical Individual
Priority to ES07100898T priority patent/ES2340958T3/es
Priority to EP07100898A priority patent/EP1947027B1/de
Priority to DE502007003215T priority patent/DE502007003215D1/de
Priority to US12/523,985 priority patent/US20100072104A1/en
Priority to JP2009546717A priority patent/JP2010516572A/ja
Priority to PCT/EP2008/050505 priority patent/WO2008090079A1/de
Publication of EP1947027A1 publication Critical patent/EP1947027A1/de
Application granted granted Critical
Publication of EP1947027B1 publication Critical patent/EP1947027B1/de
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/36—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed
    • B65D75/367—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed and forming several compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B61/00—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
    • B65B61/02—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for perforating, scoring, slitting, or applying code or date marks on material prior to packaging
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2575/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D2575/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by association or interconnecting two or more sheets or blanks
    • B65D2575/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D2575/36—One sheet or blank being recessed and the other formed or relatively stiff flat sheet material, e.g. blister packages
    • B65D2575/361—Details
    • B65D2575/362—Details with special means for gaining access to the contents
    • B65D2575/367—Details with special means for gaining access to the contents through a preformed opening in the flat sheet, e.g. the opening being defined by weakened lines

Definitions

  • the invention relates to a blister pack for the temporary storage of products, in particular medicines, and an associated method for the temporary storage of such products in a blister pack.
  • a blister pack for the weekly drug needs of a patient known to take the medication in a order by date, day of the week and time of day (morning, noon and evening and / or night) order.
  • the receiving compartments of the blister pack for receiving the respective medicaments are arranged in matrix form and with seven daily columns, each with at least three time of day compartments, which are closed overall by a continuous blister foil.
  • Affixed to the blister pack is a carton-shaped lid, on which the patient-specific the composition of the individual time of day subjects as well as prescription information concerning the respective medicaments is contained.
  • Such packaging units are for patients who need to take several different medications regularly, a help not only to forget the intake of important drugs and on the other hand to keep a reliable overview of what medications are already taken to avoid a potentially harmful over-medication ,
  • the Strip Blister must therefore have a good seal of the receiving space for the drug especially against water vapor.
  • Such a seal can be achieved for example by an aluminum foil with a minimum thickness of 0.002 mm.
  • this has the disadvantage that when a mechanical force is applied to the medicament unit by the plunger, it does not rupture reliably at the correct location or does not completely rupture, so that errors may arise during the assembly of the weekly blister.
  • the packaging system should be able to process drugs of various sizes and shapes. Since the wrong filling of a compartment of the weekly blister necessarily requires the sorting out of the entire weekly blister, errors in the "repackaging" of the medication from the blister strip in the weekly blister associated with great effort and expense.
  • the US 7,093,716 describes a child-safe blister pack for medicaments with a plurality of receiving compartments, each closed by a foil, which foil has three film layers.
  • the outermost film layer is formed of paperboard material and has tearing sections formed by perforation lines which are difficult to open by small children.
  • the first film layer preferably consisting of an air and water vapor impermeable material such as aluminum or plastic allows a secure seal of the drugs even with longer periods.
  • the second film layer preferably consisting of a mechanically rigid material such as paper or cardboard prevents unintentional tearing of the first film layer, so that it can be made comparatively thin.
  • the perforation sections of the second film layer facilitate the preferably mechanical removal of the medicaments from the strip blister. For example, by the plunger of the drug delivery station on the product (drug) a mechanical force on the Product unit applied to the film, so the film tears defined along the Perforationsabterrorisms and allows a reliable transition of the drug unit from the temporary packaging in the delivery package, such as the weekly blister.
  • First and second film layer are glued together, so that a tearing of the aluminum foil during ejection and thus the possibility of falling of film residues is avoided in the weekly blister.
  • the first film layer preferably consisting of an air and water vapor impermeable material such as aluminum or plastic closes, for example, the receiving compartments and the second film layer is formed on the first film layer.
  • the perforation is adapted to the shape and / or size of the product unit received in the receptacle.
  • the first film layer may have, for example, a thickness of 0.002 mm to 0.05 mm and the second film layer may have a thickness of 0.05 mm to 0.5 mm.
  • the depth of the perforation preferably corresponds to the thickness of the second film layer.
  • the second film layer may have on its outside a machine-readable identifier for product identification.
  • the outside of the second film layer is preferably provided with a dark surface. This dark surface also facilitates the attachment of the perforation of the second film layer by means of a controlled laser beam which removes the second film layer (for example consisting of paper material) by thermal action, while the (for example consisting of aluminum) first film layer is not damaged by the laser beam.
  • the blister pack is designed as an endless strip blister.
  • the invention also proposes a method according to claim 14.
  • the method step of forming the perforation sections in the second film layer is preferably carried out by means of a laser beam.
  • the method step of the machine removal of the products from the receiving compartments can advantageously be carried out by means of each of the receiving compartments associated, clock-controlled rams.
  • the method step of forming the perforation sections in the second film layer can be carried out, for example, before the method step of mechanically filling the receiving compartments with the products in order to allow the most efficient possible process flow.
  • the production of the perforation sections by means of a laser beam can be flexibly adjusted to different drug sizes and shapes, so that in the method according to the invention several different medicaments can be successively packed into respective endless strip blisters for temporary storage.
  • FIG. 1 shows a schematic side view of a strip blister.
  • FIG. 2 shows an enlarged schematic side view of an embodiment of the blister pack according to the invention.
  • FIG. 3 shows a plan view of the film side of a first embodiment of the blister pack according to the invention.
  • FIG. 4 shows a plan view of the film side of a second embodiment of the blister pack according to the invention.
  • FIG. 5 is a flowchart for explaining the method steps of an embodiment of the method according to the invention.
  • FIG. 1 shows a schematic side view of a strip blister for the temporary storage of products, in particular drugs.
  • the product units are preferably individually filled by machine into the blister pack formed as endless strip blister 20.
  • One filled strip blister per medication type is made available to the weekly blister placement system as a product supply. Since the drugs processed by the assembly system are consumed in very different amounts, comparatively long storage times can occur in the strip blisters.
  • an individually assigned dispensing station is provided for each drug, which conveys the respective medicaments from the endless strip blister into the corresponding receiving compartments of the packaging unit, for example by means of the spatulas of the strip blister.
  • patient-specific weekly blister packs can be filled automatically and safely with a selection of several hundred drugs.
  • the critical step is the "repackaging" of the product units from the strip blister into the weekly blister.
  • the blister pack 20 has a closure film 25 consisting of a first film layer 24 and a second film layer 26, wherein the second film layer 26 is provided with perforation sections 28 which remove the product units from the temporary packaging Facilitate blister strips and prevent tearing of the aluminum foil during ejection
  • a first embodiment of the blister pack according to the invention is in FIG. 2 shown.
  • the first film layer 24 preferably consisting of an air and water vapor impermeable material such as aluminum or plastic closes the respective receiving compartments 21 for the product units 30 (shown in phantom) and allows a secure sealing of the drugs even with longer storage times.
  • the second film layer 26 preferably consisting of a mechanically rigid material such as paper or cardboard prevents unintentional tearing of the first film layer in mechanical deformations such as winding and unwinding of the strip blister on the associated supply roll, so that the first film layer 24 itself are formed comparatively thin which helps the product removal process.
  • the perforation section 28 assigned to the respective receiving compartments in the second film layer 26 facilitates the preferably mechanical removal of the medicament units.
  • the second film layer prevents a tearing off of the abraided flap formed from the first film layer.
  • the first and second film layers are glued together, so that the aluminum foil does not tear when ejected and no film residues fall into the weekly blister.
  • the perforation section 28 is preferably adapted to the shape and / or size of the product unit received in the receptacle.
  • Two embodiments of different forms of the perforation 28 are in the FIGS. 3 and 4 shown.
  • the perforation section 28 can be as in Fig. 3 shown consist of a single continuous U-shaped line or as in Fig. 4 shown consist of two separate, complementary Perforationsabêten. Depending on the form of medication, different perforation arrangements are conceivable within the scope of the present invention.
  • the first film layer may have, for example, a thickness of 0.002 mm to 0.05 mm and the second film layer may have a thickness of 0.05 mm to 0.5 mm.
  • the depth of the perforation preferably corresponds to the thickness of the second film layer, but may also have a smaller depth, so that the second film layer 26 is not completely severed.
  • the second film layer 26 may have on its outside a machine-readable identifier 32 for product identification.
  • the perforation 28 is applied to the outer film layer 26, preferably by means of a controlled laser beam, which passes through the second, outer film layer 26 (for example consisting of paper material) thermal exposure removed, while the (for example made of aluminum) first film layer 24 is not damaged by the laser beam.
  • a controlled laser beam which passes through the second, outer film layer 26 (for example consisting of paper material) thermal exposure removed, while the (for example made of aluminum) first film layer 24 is not damaged by the laser beam.
  • this preferably has a dark surface.
  • step S4 the receiving compartments 21 of the strip blister 20 are preferably filled with the product units 30 in a manner known per se.
  • the blister compartments 21 are closed in a manner which is also known per se by applying, for example welding or sealing, the blister foil 25 and thus sealed impermeable to air and water vapor.
  • step S8 a force is exerted on the closure film 25 by the product units 30 themselves by means of the above-described plungers so that they tear open along the perforation sections 28 of the upper film layer 26 and thus reliably and without delay extend the product units 30 from the receptacles 21 be removed and in the weekly blister or the like can be repackaged.
  • the formation of the perforation sections by means of a laser beam is flexibly adjustable to different drug sizes and shapes, so that the invention allows the intermediate storage of several different drugs in strip blisters in successive steps on the same system.
  • the invention thus enables the secure temporary storage of products, in particular medicines, even over long periods of time and a reliable, preferably mechanical removal and repackaging of the products in another packaging unit such as a weekly blister.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Composite Materials (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
EP07100898A 2007-01-22 2007-01-22 Blisterpackung und Verfahren zur vorübergehenden Lagerung von Produkten Not-in-force EP1947027B1 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ES07100898T ES2340958T3 (es) 2007-01-22 2007-01-22 Envase de blisteres y procedimiento para el almacenamiento provisional de productos.
EP07100898A EP1947027B1 (de) 2007-01-22 2007-01-22 Blisterpackung und Verfahren zur vorübergehenden Lagerung von Produkten
DE502007003215T DE502007003215D1 (de) 2007-01-22 2007-01-22 Blisterpackung und Verfahren zur vorübergehenden Lagerung von Produkten
AT07100898T ATE461876T1 (de) 2007-01-22 2007-01-22 Blisterpackung und verfahren zur vorübergehenden lagerung von produkten
US12/523,985 US20100072104A1 (en) 2007-01-22 2008-01-17 Blister packaging and method for the temporary storage of products
JP2009546717A JP2010516572A (ja) 2007-01-22 2008-01-17 製品の一時貯蔵のためのブリスタパッケージング及び方法
PCT/EP2008/050505 WO2008090079A1 (de) 2007-01-22 2008-01-17 Blisterpackung und verfahren zur vorübergehenden lagerung von produkten

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP07100898A EP1947027B1 (de) 2007-01-22 2007-01-22 Blisterpackung und Verfahren zur vorübergehenden Lagerung von Produkten

Publications (2)

Publication Number Publication Date
EP1947027A1 EP1947027A1 (de) 2008-07-23
EP1947027B1 true EP1947027B1 (de) 2010-03-24

Family

ID=38171333

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07100898A Not-in-force EP1947027B1 (de) 2007-01-22 2007-01-22 Blisterpackung und Verfahren zur vorübergehenden Lagerung von Produkten

Country Status (7)

Country Link
US (1) US20100072104A1 (es)
EP (1) EP1947027B1 (es)
JP (1) JP2010516572A (es)
AT (1) ATE461876T1 (es)
DE (1) DE502007003215D1 (es)
ES (1) ES2340958T3 (es)
WO (1) WO2008090079A1 (es)

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CN104395493B (zh) 2012-06-23 2017-08-25 福瑞托-雷北美有限公司 超薄无机氧化物涂层在包装上的沉积
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Also Published As

Publication number Publication date
DE502007003215D1 (de) 2010-05-06
ATE461876T1 (de) 2010-04-15
WO2008090079A1 (de) 2008-07-31
US20100072104A1 (en) 2010-03-25
JP2010516572A (ja) 2010-05-20
EP1947027A1 (de) 2008-07-23
ES2340958T3 (es) 2010-06-11

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